English Safety Data Sheet Database 中文版 MSDS

4-Nitrophenetol

CAS No. 100-29-8 | PubChem CID 7495
Section 1. Identification
Chemical Name4-Nitrophenetol CAS No.100-29-8
Synonymsp-nitrophenetole;1-ethoxy-4-nitrobenzene; 4-nitrophenetole Chinese Name4-硝基苯乙醚
Molecular FormulaC8H9NO3 Molecular Weight167.18
UN No.3077 Data SourcePubChem (NIH/NLM)
GHS Hazard Classification
Signal Word WARNING
Pictograms GHS07 · Irritant
Hazard Statements H302H312H332
Precautionary Statements P261P264P270P271P280P301+P317P302+P352P304+P340P317P321P330P362+P364P501

Section 2. Hazards Identification

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]

H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]

P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P317, P321, P330, P362+P364, and P501 (click each P-code to see the statement)

The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Section 9. Physical and Chemical Properties

Solid; [Hawley] Deep brown crystals; [MSDSonline]

PRISMS FROM ALCOHOL, WATER OR ETHER

SLIGHTLY SOL IN WATER, ALCOHOL; SOL IN HOT PETROLEUM ETHER; VERY SOL IN HOT ALCOHOL, DIETHYL ETHER; SOL IN ALL PROPORTIONS IN ACETONE, BENZENE

1.1176 AT 100 °C/4 °C

0.00623 [mmHg]

Diamagnetic susceptibility

Magnetic susceptibility

Nitrogen Compounds -> Other Aromatics (Nitrogen)

Section 11. Toxicological Information

Neurotoxin - Other CNS neurotoxin

Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

Methemoglobinemia - The presence of increased methemoglobin in the blood; the compound is classified as secondary toxic effect

WHEN ADDED TO FOOD OF LARVAL & IMAGO DROSOPHILA, IT INCR INCIDENCE OF DOMINANT LETHAL MUTATIONS AMONG OFFSPRING & INCR PERCENTAGE OF UNFERTILIZED EGGS. ORAL ADMIN TO RATS INCR INCIDENCE OF CHROMOSOMAL FRAGMENTATION, BRIDGING & REARRANGEMENT IN LIVER CELLS.

PREVIOUSLY RECOMMENDED MAX PERMISSIBLE LIMITS IN DRINKING WATER APPARENTLY SHOULD BE REVISED DOWNWARD.

Section 12. Ecological Information

PREVIOUSLY RECOMMENDED MAX PERMISSIBLE LIMITS IN DRINKING WATER APPARENTLY SHOULD BE REVISED DOWNWARD.

Source: PubChem CID 7495 (NIH/NLM, public domain). Retrieved from PubChem, a public-domain chemistry database maintained by the U.S. National Library of Medicine. Last updated: 2026-08-02 09:24:24.
Disclaimer: This information is compiled for reference only and does not replace the manufacturer's official Safety Data Sheet. Always consult the supplier's SDS before handling any chemical.