Silicon tetrachloride

H315: Causes skin irritation [Warning Skin corrosion/irritation]

H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

This chemical does not meet GHS hazard criteria for 0.2% (1 of 440) of reports.

H301+H331 (32.3%): Toxic if swallowed or if inhaled [Danger Acute toxicity, oral; acute toxicity, inhalation]

H301 (61.8%): Toxic if swallowed [Danger Acute toxicity, oral]

H314 (30.2%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

H315 (69.5%): Causes skin irritation [Warning Skin corrosion/irritation]

H318 (15.5%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

H319 (69.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H331 (61.8%): Toxic if inhaled [Danger Acute toxicity, inhalation]

H335 (91.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P260, P261, P264, P264+P265, P270, P271, P280, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 440 reports by companies from 20 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria per 1 of 440 reports by companies.

There are 19 notifications provided by 439 of 440 reports by companies with hazard statement code(s).

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

H301: Toxic if swallowed [Danger Acute toxicity, oral]

H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]

H331: Toxic if inhaled [Danger Acute toxicity, inhalation]

H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]

P260, P261, P264, P264+P265, P270, P271, P280, P301+P316, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P308+P316, P316, P317, P321, P330, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure]

P260, P264, P264+P265, P270, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P308+P316, P316, P317, P321, P363, P405, and P501 (click each P-code to see the statement)

Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.

Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . Wear protective gloves when administering first aid.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Do NOT induce vomiting. Give nothing to drink. Refer for medical attention .

Get medical attention at once following any exposure to this compound.

INHALATION: remove victim from contaminated atmosphere; if breathing has ceased, start mouth-to-mouth resuscitation; oxygen should only be administered by an experienced person when authorized by a physician; keep patient warm and comfortable.

EYES: immediately flush with large quantities of running water for a minimum of 15 min.; continue irrigation for an additional 15 min. if physician is (USCG, 1999)

General First Aid:

· Call 911 or emergency medical service.

· Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.

· Move victim to fresh air if it can be done safely.

· Administer oxygen if breathing is difficult.

· If victim is not breathing:

-- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.

-- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).

-- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.

· Remove and isolate contaminated clothing and shoes.

· For minor skin contact, avoid spreading material on unaffected skin.

· In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.

· For severe burns, immediate medical attention is required.

· Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed.

· Keep victim calm and warm.

· Keep victim under observation.

· For further assistance, contact your local Poison Control Center.

· Note: Basic Life Support (BLS) and Advanced Life Support (ALS) should be done by trained professionals.

Specific First Aid:

· For corrosives, in case of contact, immediately flush skin or eyes with running water for at least 30 minutes. Additional flushing may be required.

· In case of skin contact with Hydrofluoric acid (UN1790), if calcium gluconate gel is available, rinse 5 minutes, then apply gel. Otherwise, continue rinsing until medical treatment is available.

In Canada, an Emergency Response Assistance Plan (ERAP) may be required for this product. Please consult the shipping paper and/or the "ERAP" section.

Excerpt from ERG Guide 157 [Substances - Toxic and/or Corrosive (Non-Combustible / Water-Sensitive)]:

Note: Some foams will react with the material and release corrosive/toxic gases.

SMALL FIRE: CO2 (except for Cyanides), dry chemical, dry sand, alcohol-resistant foam.

LARGE FIRE: Water spray, fog or alcohol-resistant foam. If it can be done safely, move undamaged containers away from the area around the fire. Avoid aiming straight or solid streams directly onto the product. Dike runoff from fire control for later disposal.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. (ERG, 2024)

NO water. In case of fire in the surroundings, use appropriate extinguishing media. In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water.

DO NOT USE WATER OR FOAM ON ADJACENT FIRES.

Materials and methods used for the field testing of foams on silicon tetrachloride are described. Two foams were tested incl a high water retention foam with stability over a wide pH range & an ammoniated foam that converts the chlorine portion of the foams to ammonium chloride rather than hydrogen chloride. Results show the application of foam significantly reduced the vapor hazard from spilled silicon tetrachloride.

Contact with water in foam applied to adjacent fires will produce irritating fumes of hydrogen chloride.

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Keep unauthorized personnel away.

· Stay upwind, uphill and/or upstream.

· Ventilate closed spaces before entering, but only if properly trained and equipped.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

· All equipment used when handling the product must be grounded.

· Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.

· Stop leak if you can do it without risk.

· A vapor-suppressing foam may be used to reduce vapors.

· DO NOT GET WATER INSIDE CONTAINERS.

· Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material.

· Prevent entry into waterways, sewers, basements or confined areas.

Small Spill

· Cover with DRY earth, DRY sand or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain.

· Use clean, non-sparking tools to collect material and place it into loosely covered plastic containers for later disposal.

HCl - when spill Silicon tetrachloride into water.

Excerpt from ERG Guide 157 [Substances - Toxic and/or Corrosive (Non-Combustible / Water-Sensitive)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: See ERG Table 1 - Initial Isolation and Protective Action Distances on the UN/NA 1818 datasheet.

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Immediate precautionary measure

· Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

· For highlighted materials: see Table 1 - Initial Isolation and Protective Action Distances.

· For non-highlighted materials: increase the immediate precautionary measure distance, in the downwind direction, as necessary.

· If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

When spilled in water

Small spill:

- ISOLATE in all directions: 30 m (100 ft)

Large spill:

- ISOLATE in all directions: 60 m (200 ft)

- PROTECT people from downwind during DAY time: 0.1 km (0.1 mi)

- PROTECT people from downwind during NIGHT time: 0.1 km (0.1 mi)

- PROTECT people from downwind during DAY time: 0.6 km (0.4 mi)

- PROTECT people from downwind during NIGHT time: 2.0 km (1.3 mi)

Personal protection: chemical protection suit including self-contained breathing apparatus. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in dry sand or inert absorbent. Then store and dispose of according to local regulations.

Spills can be rendered harmless by anhydrous soda.

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

/LABORATORY QUANTITIES/: Chemical treatment: Transfer into an evaporating dish containing sodium bicarbonate. Spray with ammonia (6m-NH4OH) /6 M-ammonium hydroxide/ while stirring and then spread with crushed ice. Continue spraying with ammonia until the smoke of ammonium chloride partly subsides and add iced water while stirring. Neutralize and slowly transfer the mixture into a drain with running water.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. Quality assurance to ascertain the completeness of the cleaning procedures should be implemented before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at end of shift, but should remain at employee's place of work for cleaning.

Excerpt from ERG Guide 157 [Substances - Toxic and/or Corrosive (Non-Combustible / Water-Sensitive)]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. A vapor-suppressing foam may be used to reduce vapors. DO NOT GET WATER INSIDE CONTAINERS. Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material. Prevent entry into waterways, sewers, basements or confined areas.

SMALL SPILL: Cover with DRY earth, DRY sand or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain. Use clean, non-sparking tools to collect material and place it into loosely covered plastic containers for later disposal. (ERG, 2024)

Keep under inert gas. Separated from food and feedstuffs and incompatible materials. See Chemical Dangers. Dry. Well closed. Keep in a well-ventilated room.

Storage temperature: ambient.

IN THE ABSENCE OF WATER IT HAS PRACTICALLY NO ACTION ON IRON, STEEL, OR THE COMMON METALS AND ALLOYS, AND CAN BE STORED AND HANDLED IN METAL EQUIPMENT WITHOUT DANGER.

ALL CONTAINERS, PIPES, APPARATUS, INSTALLATIONS & STRUCTURES USED FOR MFR, STORAGE, TRANSPORT OR USE OF THESE SUBSTANCES MUST BE OF MATERIAL RESISTANT TO CORROSIVE SUBSTANCES OR BE PROTECTED BY SUITABLE COATINGS... ALL CONTAINERS OR RECEPTACLES SHOULD BE CLEARLY LABELLED TO INDICATE THEIR CONTENTS & SHOULD BEAR DANGER SYMBOL FOR CORROSIVES. /CORROSIVE SUBSTANCES/

· Wear positive pressure self-contained breathing apparatus (SCBA).

· Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE.

· Structural firefighters' protective clothing provides thermal protection but only limited chemical protection.

TIH (Toxic Inhalation Hazard) - Term used to describe gases and volatile liquids that are toxic when inhaled. Some are TIH materials themselves, e.g., chlorine, and some release TIH gases when spilled in water, e.g., chlorosilanes. [ERG 2016].

AEGL 1: Notable discomfort, irritation, or certain asymptomatic non-sensory effects. However, the effects are not disabling and are transient and reversible upon cessation of exposure (Unit: ppm)

AEGL 2: Irreversible or other serious, long-lasting adverse health effects or an impaired ability to escape (Unit: ppm)

AEGL 3: Life-threatening health effects or death (Unit: ppm)

AEGLs Status: Final

0.45 [ppm]

5.5 [ppm]

25 [ppm]

· Note: Some foams will react with the material and release corrosive/toxic gases.

Small Fire

· CO2 (except for Cyanides), dry chemical, dry sand, alcohol-resistant foam.

Large Fire

· Water spray, fog or alcohol-resistant foam.

· If it can be done safely, move undamaged containers away from the area around the fire.

· Avoid aiming straight or solid streams directly onto the product.

· Dike runoff from fire control for later disposal.

Fire Involving Tanks, Rail Tank Cars or Highway Tanks

· Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.

· Do not get water inside containers.

· Cool containers with flooding quantities of water until well after fire is out.

· Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.

· ALWAYS stay away from tanks in direct contact with flames.

ERPG-1: 0.75 ppm - one hour exposure limit: 1 = mild transient health effects or objectionable odor [AIHA]

ERPG-2: 5 ppm - one hour exposure limit: 2 = impaired ability to take protective action [AIHA]

ERPG-3: 37 ppm - one hour exposure limit: 3 = life threatening health effects [AIHA]

Emergency Response Planning Guidelines (ERPG): ERPG(1) 0.75 ppm (no more than mild, transient effects) for up to 1 hr exposure; ERPG(2) 5 ppm (without serious, adverse effects) for up to 1 hr exposure; ERPG(3) 37 ppm (not life threatening) up to 1 hr exposure.

Workplace Environmental Exposure Level (WEEL): Short-term Exposure Limit (STEL) 1 ppm, ceiling.

No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.

The substance and the vapour are corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of the vapour may cause lung oedema. Inhalation of the vapour may cause asthma-like reactions. The effects may be delayed. Exposure could cause death. Medical observation is indicated.

Acid-canister-type gas mask or self-contained breathing apparatus; goggles or face shield; rubber gloves; other protective clothing to prevent contact with skin. (USCG, 1999)

ACID-CANISTER-TYPE /NIOSH CERTIFIED RESPIRATOR/ OR SELF-CONTAINED BREATHING APPARATUS; GOGGLES OR FACE SHIELD; RUBBER GLOVES; OTHER PROTECTIVE CLOTHING TO PROTECT SKIN.

...PREVENTIVE MEASURES SHOULD BE DIRECTED PRIMARILY AT PREVENTING OR MINIMIZING CONTACT BETWEEN CORROSIVE SUBSTANCES & SKIN, MUCOUS MEMBRANES & EYES. /CORROSIVE SUBSTANCES/

.../PROTECTIVE/ EQUIPMENT SHOULD.../INCL/ CORROSION-RESISTANT & IMPERVIOUS SUITS...FOOT...HAND & ARM...HEAD...& EYE & FACE PROTECTION; WHERE CORROSIVE GASES MAY BE EXPECTED...RESP PROTECTIVE EQUIPMENT IS REQUIRED... /CORROSIVE SUBSTANCES/

...NATURAL RUBBERS, SYNTHETIC RUBBERS, POLYVINYL CHLORIDE, POLYPROPYLENE OR POLYETHYLENE EITHER IN SHEET FORM OR WITH FABRIC BACKING ARE SUITABLE /FOR PERSONAL PROTECTIVE EQUIPMENT/. /CORROSIVE SUBSTANCES/

STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR!

Use ventilation, local exhaust or breathing protection.

Protective gloves. Protective clothing.

Silicon tetrachloride is a colorless, fuming liquid with a pungent odor. It is decomposed by water to hydrochloric acid with evolution of heat. It is corrosive to metals and tissue in the presence of moisture. It is used in smoke screens, to make various silicon containing chemicals, and in chemical analysis.

Colorless fuming liquid with a suffocating odor; [HSDB]

COLOURLESS CLEAR FUMING LIQUID WITH PUNGENT ODOUR.

Colorless, clear, mobile, fuming liquid

Suffocating odor

135.7 °F at 760 mmHg (USCG, 1999)

135.7 °F

57.57 °C @760 [mm Hg]

-94 °F (USCG, 1999)

Miscible with benzene, ether, chloroform, petroleum ether

Miscible in all proportions with carbon tetrachloride, tin tetrachloride, titanium chloride, sulfur mono- & dichlorides

Solubility in water: reaction

1.48 at 68 °F (USCG, 1999) - Denser than water; will sink

1.52 @ 0 °C/4 °C

Density: 1.90 @ -97 °C; Liq: 1.483 @ 20 °C; Decomp in alcohol

Relative density (water = 1): 1.48

1.482 @25 °C

7.59 g/l

Relative vapor density (air = 1): 5.9

236.0 [mmHg]

236 mm Hg @ 25 °C /Calculated from experimentally derived coefficients/

Vapor pressure, kPa at 20 °C: 26

When heated to decomp, it emits toxic fumes of /hydrogen chloride./

Corrosive to most metals when water is present

29.7 kJ/mol at 25 °C

19.6 DYNES/CM= 0.0196 N/M AT 20 °C

Polymerizes easily

INDEX OF REFRACTION: 1.412 AT 20 °C/D

Decomp by water with much heat into silicic acid and hydrochloric acid.

29Si nuclear magnetic resonance spectrum

Gibbs energy

Schoenflies notation

Acentric factor

Boiling point

Chemical bond

Chemical shift

Critical point

Crystal structure

Enthalpy

Excess enthalpy

Fumes in air. Decomposed by water or moist air with much heat generated and forms silicic acid and hydrochloric acid [Merck 11th ed. 1989].

Silicon tetrachloride reacts vigorously with water to generate gaseous HCl. Based on a scenario where the chemical is spilled into an excess of water (at least 5 fold excess of water), half of the maximum theoretical yield of Hydrogen Chloride gas will be created in 0.38 minutes. Experimental details are in the following: "Development of the Table of Initial Isolation and Protective Distances for the 2008 Emergency Response Guidebook", ANL/DIS-09-2, D.F. Brown, H.M. Hartmann, W.A. Freeman, and W.D. Haney, Argonne National Laboratory, Argonne, Illinois, June 2009.

Chlorosilanes

Water-Reactive

Air-Reactive

CSL00126

Silicon tetrachloride + LITHIUM ALUMINUM HYDRIDE

LiAlH4 reduction of SiCl4 releases silane

Explosive,Flammable,Gas Emitter,Pyrophoric

Reduction

We would like to report a potential hazard for the synthetic procedure outlined in Physical Review B (1999, 60, 2704). This contribution is widely referenced and describes a procedure for preparing hydride surface-terminated silicon nanoparticles via lithium aluminum hydride reduction of SiCl4 in micellular tetrahydrofuran (THF) solutions. The authors incorrectly report that this reaction produces hydrogen gas that is presumably released into the "controlled-atmosphere glove box." There is no mention of pyrophoric by-products. We recently attempted to reproduce this reported procedure and performed all our steps on a double-vacuum manifold equipped with argon working gas and an oil bubbler. We used standard experimental techniques for handling air-sensitive compounds. With our experimental design, gas by-products are carried out of the reaction vessel by flowing working gas and are released from the oil bubbler into the ambient atmosphere of the fume hood. From the article cited, there is no reason to expect any adverse events from the procedural difference of interchanging a glove box for a double manifold. The release of hydrogen gas from the oil bubbler into the atmosphere should have been inconsequential. Furthermore, synthetic chemists well-versed in manipulating air-sensitive compounds often find a double manifold more effective than using a glove box. Upon addition of a THF LiAlH4 solution to a THF solution of SiCl4, we observed vigorous bubbling consistent with the literature report. To our surprise, a bright orange flame was released from our oil bubbler. It was impossible for the authors of the aforementioned contribution to make this observation because a gaseous reaction by-product was doubtless captured by the glove box circulation system and was never released into the atmosphere. Fortunately, no one was injured when this "controlled burn" occurred in our laboratory. Subsequent literature searches have revealed that the gas produced is incorrectly identified as hydrogen in the 1999 reference. In fact, the reaction LiAlH4 + SiCl4 t LiCl + AlCl3 + SiH4 occurs in ethereal solutions and has been known for some time to produce pyrophoric silane (J. Am. Chem. Soc. 1947, 69, 1199). While we did isolate some Si nanoparticles from the reaction mixture and confirmed that they were indeed hydride-terminated, we caution other researchers from carrying out this reaction without exercising extreme care.

http://pubs.acs.org/cen/safety/20051219.html

CSL00170

Silicon tetrachloride + Water

Hydrogen chloride gas was produced and accidentally released from the containment system

Gas Emitter

Not Available

User Reported

04/22/2022

04/21/2022

Chlorosilanes, such as SILICON TETRACHLORIDE, are compounds in which silicon is bonded to from one to four chlorine atoms with other bonds to hydrogen and/or alkyl groups. Chlorosilanes react with water, moist air, or steam to produce heat and toxic, corrosive fumes of hydrogen chloride. They may also produce flammable gaseous H2. They can serve as chlorination agents. Chlorosilanes react vigorously with both organic and inorganic acids and with bases to generate toxic or flammable gases. This material is incompatible with alkali metals and dimethyl sulfoxide.

Will react with water or steam to produce heat, toxic and corrosive fumes. /Silicon chloride/

Reacts with water to form hydrochloric acid. Violent reaction with sodium; potassium.

In the preparation of ethyl polysilicate by mixing tetrachlorosilane and industrial methylated spirit containing some water, failure of the agitator is thought to have led to layering of the alcohol over the dense chloride. Evolution of hydrogen chloride led to mixing of the layers, and a greatly increased rate of reaction and self-accelerating gas evolution which burst the reactor.

In absence of diluent or other effective control of reaction rate, /dimethyl/ sulfoxide reacts violently or explosively with tetrachlorosilane.

A MIXTURE OF POTASSIUM AND.../SILICON TETRACHLORIDE/ PRODUCES A STRONG EXPLOSION ON IMPACT.

The substance can be absorbed into the body by inhalation of its vapour and by ingestion.

Cough. Sore throat. Burning sensation. Laboured breathing. Shortness of breath. Symptoms may be delayed.

Redness. Pain. Blisters. Skin burns.

Redness. Pain. Severe deep burns.

Burning sensation. Abdominal pain. Shock or collapse.

Dermatotoxin - Skin burns.

Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.

LC50 (rat) = 8,000 ppm/4H

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patent can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Chlorine and related compounds/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in respiratory arrest. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W TKO /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's to support vital signs if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . Consider vasopressors to treat hypotension without signs of hypovolemia ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Chlorine and related compounds/

MAY BE IRRITATING TO EYES ...

A spill of silicon tetrachloride caused the evacuation of several thousand people from an industrial park; 28 persons sought medical attention. Five of the workers experienced recurrent headaches, and two complained of pedal dysesthesias after the accident. Although temporal relationship between the exposure and onset of these symptoms is notable, no definite etiologic relationship could be established.

.../CHLOROSILANES/ CONSIDERED NON-CORROSIVE IN THEIR NATURAL, DRY STATE MAY BECOME CORROSIVE WHEN IN CONTACT WITH WATER OR MOISTURE OF SKIN & MUCOUS MEMBRANES. ...DURING...HYDROLYSIS, CORROSIVE HALOGEN COMPOUNDS ARE RELEASED. /CORROSIVE SUBSTANCES/

THERE IS...NO EVIDENCE OF SILICOSIS-TYPE LESIONS IN PERSONS HANDLING CHLOROSILANES. /CORROSIVE SUBSTANCES/

For more Human Toxicity Excerpts (Complete) data for SILICON TETRACHLORIDE (7 total), please visit the HSDB record page.

VAPOR IS IRRITATING TO EYES & RESP TRACT, & A SMALL DROP OF ... /TETRACHLOROSILANE/ ON RABBIT EYES CAUSES SEVERE DAMAGE.

/WHEN INSTILLED/...INTO EYE OF RABBIT ALL THESE COMPD /METHYL & ETHYL CHLOROSILANES/, EVEN @ VERY LOW DOSES (0.05 ML), CAUSED SEVERE BURNS OF CORNEA & EYELIDS. .../WHEN APPLIED/ TO SKIN OF RABBIT THE REGION ATTACKED BY CHLOROSILANES BLANCHES & BLISTERS APPEAR; ACTION IS MORE MARKED THE DAMPER SURFACE OF SKIN. /CHLOROSILANES/

/VIA INHALATION/ THEY HAVE A CORROSIVE ACTION WHEN BROUGHT INTO CONTACT WITH MUCOUS MEMBRANES. /CHLOROSILANES/

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

/LABORATORY QUANTITIES/: Chemical treatment: Transfer into an evaporating dish containing sodium bicarbonate. Spray with ammonia (6m-NH4OH) /6 M-ammonium hydroxide/ while stirring and then spread with crushed ice. Continue spraying with ammonia until the smoke of ammonium chloride partly subsides and add iced water while stirring. Neutralize and slowly transfer the mixture into a drain with running water.

If ... THERE IS NO FIRE, go directly to the Table of Initial Isolation and Protective Action Distances /(see table below)/ ... to obtain initial isolation and protective action distances. IF THERE IS A FIRE, or IF A FIRE IS INVOLVED, go directly to the appropriate guide /(see guide(s) below)/ and use the evacuation information shown under PUBLIC SAFETY.

Table: Table of Isolation and Protective Action Distances for Silicon tetrachloride (when spilled in water) [Table#1977]

Table of Water-Reactive Materials Which Produce Toxic Gases

Table: Materials Which Produce Large Amounts of Toxic-by-Inhalation (TIH) Gas(es) When Spilled in Water [Table#1978]

/GUIDE 157: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE/WATER -SENSITIVE)/ Health: TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns, or death. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat which will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

/GUIDE 157: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE/WATER -SENSITIVE)/ Fire or Explosion: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Vapors may accumulate in confined areas (basement, tanks, hopper/tank cars etc.). Substance will react with water (some violently), releasing corrosive and/or toxic gases. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or contaminated with water.

For more DOT Emergency Guidelines (Complete) data for SILICON TETRACHLORIDE (10 total), please visit the HSDB record page.

UN 1818; SILICON TETRACHLORIDE

IMO 8.0; Silicon tetrachloride

49 323 70; Silicon chloride, silicon tetrachloride

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Corrosive

Do not transport with food and feedstuffs.

Symbol: Xi; R: 14-36/37/38; S: (2)-7/8-26

UN Hazard Class: 8; UN Pack Group: II