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Hydrazine hydrate (1:1)

CAS No. 10217-52-4 | PubChem CID 24654
Section 1. Identification
Chemical NameHydrazine hydrate (1:1) CAS No.10217-52-4
Synonymsdiamidehydrate; hydrazinehydrate (containing36% water) Chinese Name水合肼[含水36%]
Molecular FormulaH4N2·H2O Molecular Weight50.08
UN No.2030 Data SourcePubChem (NIH/NLM)
GHS Hazard Classification
Signal Word DANGER
Pictograms GHS02 · Flammable GHS05 · Corrosive GHS06 · Acute Toxic GHS07 · Irritant GHS08 · Health Hazard GHS09 · Environmental Hazard
Hazard Statements H226H301H311H314H317H318H330H331H350H400H410H300H227H341H351H370H372
Precautionary Statements P203P210P233P240P241P242P243P260P261P262P264P264+P265P270P271P272P273P280P284P301+P316P301+P330+P331P302+P352P302+P361+P354P303+P361+P353P304+P340P305+P354+P338P316P317P318P320P321P330P333+P317P361+P364P362+P364P363P370+P378P391P403+P233P403+P235P405P501P308+P316P319P403

Section 2. Hazards Identification

This chemical does not meet GHS hazard criteria for 0.5% (1 of 214) of reports.

H226 (95.3%): Flammable liquid and vapor [Warning Flammable liquids]

H301+H311 (40.7%): Toxic if swallowed or in contact with skin [Danger Acute toxicity, oral; acute toxicity, dermal]

H301 (97.2%): Toxic if swallowed [Danger Acute toxicity, oral]

H311 (98.6%): Toxic in contact with skin [Danger Acute toxicity, dermal]

H314 (99.5%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

H317 (99.5%): May cause an allergic skin reaction [Warning Sensitization, Skin]

H318 (43%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

H330 (44.4%): Fatal if inhaled [Danger Acute toxicity, inhalation]

H331 (54.7%): Toxic if inhaled [Danger Acute toxicity, inhalation]

H350 (99.1%): May cause cancer [Danger Carcinogenicity]

H400 (98.6%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

H410 (99.5%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P203, P210, P233, P240, P241, P242, P243, P260, P261, P262, P264, P264+P265, P270, P271, P272, P273, P280, P284, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P318, P320, P321, P330, P333+P317, P361+P364, P362+P364, P363, P370+P378, P391, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 214 reports by companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria per 1 of 214 reports by companies.

There are 13 notifications provided by 213 of 214 reports by companies with hazard statement code(s).

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

This chemical does not meet GHS hazard criteria for 11.1% (1 of 9) of reports.

H226 (44.4%): Flammable liquid and vapor [Warning Flammable liquids]

H300 (44.4%): Fatal if swallowed [Danger Acute toxicity, oral]

H301+H311+H331 (11.1%): Toxic if swallowed, in contact with skin or if inhaled [Danger Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]

H301 (33.3%): Toxic if swallowed [Danger Acute toxicity, oral]

H311 (77.8%): Toxic in contact with skin [Danger Acute toxicity, dermal]

H314 (77.8%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

H317 (77.8%): May cause an allergic skin reaction [Warning Sensitization, Skin]

H331 (33.3%): Toxic if inhaled [Danger Acute toxicity, inhalation]

H350 (88.9%): May cause cancer [Danger Carcinogenicity]

H400 (77.8%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

H410 (77.8%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P203, P210, P233, P240, P241, P242, P243, P260, P261, P262, P264, P270, P271, P272, P273, P280, P284, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P318, P320, P321, P330, P333+P317, P361+P364, P362+P364, P363, P370+P378, P391, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 9 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria per 1 of 9 reports by companies.

There are 4 notifications provided by 8 of 9 reports by companies with hazard statement code(s).

H350: May cause cancer [Danger Carcinogenicity]

P203, P280, P318, P405, and P501 (click each P-code to see the statement)

H227: Combustible liquid [Warning Flammable liquids]

H301: Toxic if swallowed [Danger Acute toxicity, oral]

H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

H317: May cause an allergic skin reaction [Warning Sensitization, Skin]

Section 8. Exposure Controls / Personal Protection

0.10 [ppm]

13 [ppm]

35 [ppm]

Section 9. Physical and Chemical Properties

Liquid; Other Solid; Liquid

A colorless fuming liquid with a faint ammonia-like odor; Corresponds to a 64% aqueous solution of hydrazine in water; [CAMEO]

119 °C @760 [mm Hg]

-51.7 °C

1.03 @ 21°C

Nitrogen Compounds -> Hydrazines

Corrosives

Flammable agents - 2nd degree

Reactive agents - 2nd degree

Section 11. Toxicological Information

Neurotoxin - Other CNS neurotoxin

Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

Methemoglobinemia - The presence of increased methemoglobin in the blood; the compound is classified as secondary toxic effect

Dermatotoxin - Skin burns.

Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.

Source: PubChem CID 24654 (NIH/NLM, public domain). Retrieved from PubChem, a public-domain chemistry database maintained by the U.S. National Library of Medicine. Last updated: 2026-08-02 09:21:01.
Disclaimer: This information is compiled for reference only and does not replace the manufacturer's official Safety Data Sheet. Always consult the supplier's SDS before handling any chemical.