Diisopropyl peroxydicarbonate

H241 (60%): Heating may cause a fire or explosion [Danger Self-reactive substances and mixtures; Organic peroxides]

H242 (40%): Heating may cause a fire [Danger Self-reactive substances and mixtures; Organic peroxides]

H302 (30%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

H336 (10%): May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]

H373 (10%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

H400 (50%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

H410 (30%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

H411 (40%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P210, P234, P235, P240, P260, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P370+P378, P370+P380+P375[+P378], P391, P403, P403+P233, P405, P410, P411, P420, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 10 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

H241: Heating may cause a fire or explosion [Danger Self-reactive substances and mixtures; Organic peroxides]

H315: Causes skin irritation [Warning Skin corrosion/irritation]

H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]

P210, P234, P235, P240, P264, P264+P265, P280, P302+P352, P305+P354+P338, P317, P321, P332+P317, P362+P364, P370+P380+P375[+P378], P403, P410, P411, P420, and P501 (click each P-code to see the statement)

INHALATION: move to uncontaminated atmosphere; if breathing is difficult, give oxygen.

EYES: flush with copious amounts of water.

SKIN: wash off with isopropyl alcohol and water; call a physician. (USCG, 1999)

Fire Extinguishing Agents Not to Be Used: All extinguishing agents may be ineffective.

Fire Extinguishing Agents: Water (USCG, 1999)

FIGHT FIRES FROM EXPLOSION-RESISTANT LOCATION. IN ADVANCED OR MASSIVE FIRES, AREA SHOULD BE EVACUATED. ... IT IS ESSENTIAL TO MAINTAIN PROPER TEMP CONTROL OF REFRIGERATION SYSTEM AS MATERIAL WILL DECOMP @ 53 °F TO RELEASE FLAMMABLE PRODUCTS WHICH MUST BE PROPERLY VENTED. CLEAN-UP & SALVAGE OPERATIONS SHOULD NOT BE ATTEMPTED UNTIL DEEP-FREEZE UNIT HAS COOLED COMPLETELY. DUE CAUTION SHOULD BE EXERCISED BECAUSE OF POSSIBILITY OF ADVERSE CONTAMINATION AND CHEM CHANGE AFTER HEAT EXPOSURE.

Excerpt from ERG Guide 148 [Organic Peroxides (Heat and Contamination Sensitive / Temperature Controlled)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

LARGE SPILL: Consider initial evacuation for at least 250 meters (800 feet) in all directions.

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

Excerpt from ERG Guide 148 [Organic Peroxides (Heat and Contamination Sensitive / Temperature Controlled)]:

DO NOT allow the substance to warm up. Use a coolant agent such as dry ice or ice (wear thermal protective gloves). If this is not possible or none can be obtained, evacuate the area immediately. ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. Keep combustibles (wood, paper, oil, etc.) away from spilled material. Do not touch or walk through spilled material. Stop leak if you can do it without risk.

SMALL SPILL: Pick up with inert, damp, non-combustible material using clean, non-sparking tools and place into loosely covered plastic containers for later disposal.

LARGE SPILL: Dike far ahead of liquid spill for later disposal. Prevent entry into waterways, sewers, basements or confined areas. DO NOT CLEAN-UP OR DISPOSE OF, EXCEPT UNDER SUPERVISION OF A SPECIALIST. (ERG, 2024)

SHOULD BE STORED IN DEEP-FREEZE...UNIT IN WELL-VENTILATED, UNHEATED, WELL-DETACHED, NONCOMBUSTIBLE BUILDING...MUST BE STORED @ LOW TEMP (BELOW 0 °F). REFRIGERATED PRODUCT SHOULD BE PLACED IN DEEP-FREEZE BOX WITH FREE-OPENING COVER IN...BUILDING. REFRIGERATING UNIT & ALL ELECTRICAL EQUIP SHOULD BE OUTSIDE... ALARM SYSTEM.../NEEDED/ TO INDICATE ANY ABNORMAL TEMP...WITHIN DEEP-FREEZE BOX. PROTECT AGAINST PHYSICAL DAMAGE. DO NOT OPEN CONTAINERS IN STORAGE BUILDING.

6.4 [mg/m3]

71 [mg/m3]

420 [mg/m3]

Rubber gloves and shoes; hard hat; chemical splash goggles; plastic apron; respirator (depending on solvent used) (USCG, 1999)

Persons handling organic peroxides should use safety glasses with side shields, goggles or face shields for eye protection. Emergency eyewash facilities should be provided. Gloves, aprons & other protective clothing as necessary should be used to prevent skin contact. Clothing & equipment that generate static electricity should be avoided. /Organic peroxides/

Diisopropyl peroxydicarbonate appears as a white solid (shipped packed in Dry Ice to stabilize) with a sharp unpleasant odor. Insoluble in sater and sinks in water. Used as polymerization catalyst. (USCG, 1999)

Colorless solid; mp = 8-10 deg C; [Hawley]

Crystalline solid

Colorless

17.2 °C @760 [mm Hg]

50 °F (USCG, 1999)

36016 °C

Almost insol in water; miscible with aliphatic and aromatic hydrocarbons, esters, ethers and chlorinated hydrocarbons

1.08 at 59 °F (USCG, 1999) - Denser than water; will sink

1.080 @ 15.5 °C/4 °C

1.080 @ 15°C

Spontaneous decomposition at room temperature releases flammable and corrosive products.

When heated to decomposition it emits acrid smoke and fumes.

Index of refraction: 1.4034 @ 20 °C/D

SELF-ACCELERATING DECOMP TEMP 53 °F

Decomposition temperature: 35-38 °C.

Temperature for half-life for 1 hour: 61 °C; half-life at 20 °C: 400 hours, at 40 °C: 18 hours, at 60 °C: 1.2 hours.

Rapid decomposition at 63 °F (17.2 °C)

Other Classes -> Peroxides, Organic

Flammable agents - 4th degree

Reactive agents - 4th degree

FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR

Highly flammable. Insoluble in water. Spontaneous decomposition at room temperature releases flammable toxic products.

Peroxides, Organic

Highly Flammable

Explosive

Strong Oxidizing Agent

Decomposes at Elevated Temperatures (

DIISOPROPYL PEROXYDICARBONATE decomposes violently or explosively at temperatures 0-10 °C owing to self- accelerating exothermic decomposition; Several explosions were due to shock, heat, or friction; amines and certain metals can cause accelerated decomposition [Bretherick 1979 p. 156]. Spontaneous decomposition possible at room temperature to release flammable and corrosive products (presence of stabilizer reduces this possibility). A strong oxidizing agent. May ignite organic compounds on contact, hence a fire risk. Strongly reduced material such as sulfides, nitrides, and hydrides can react explosively. Reacts at least to produce heat when mixed with members of most chemical classes. These reactions often generate gases (toxic and nontoxic). Subject to decomposition, buildup of heat and even an explosion if contaminated with a catalyst (often a transition metal such as cobalt, iron, manganese, nickel, or vanadium or a salt of a transition metal).

Explodes on contact with amines or potassium iodide. May explode on contact with organic matter.

LD50 Rat oral 2140 mg/kg

LD50 Rabbit skin 2025 mg/kg

Should be washed promptly from the skin to prevent irritation. /Peroxides, org/

Basic Treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Do not attempt to neutralize because of exothermic reaction. Cover skin burns with dry, sterile dressings after decontamination ... . /Organic peroxides/

Advanced Treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in respiratory arrest. Early intubation, at the first sign of upper airway obstruction, may be necessary. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Organic peroxides/

Prolonged skin contact or splashes in the eyes may cause injury. Some organic peroxide vapors are irritating and may also cause headaches, intoxication similar to alcohol and lung edema if inhaled in high concentrations. /Organic peroxides/

Moderately toxic by ingestion and skin contact.

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

/GUIDE 148: ORGANIC PEROXIDES (HEAT AND CONTAMINATION SENSITIVE/TEMPERATURE CONTROLLED )/ Fire or Explosion: May explode from heat, contamination or loss of temperature control. These materials are particularly sensitive to temperature rises. Above a given "Control Temperature" they decompose violently and catch fire. May ignite combustibles (wood, paper, oil, clothing, etc.). May ignite spontaneously if exposed to air. May be ignited by heat, sparks or flames. May burn rapidly with flare-burning effect. Containers may explode when heated. Runoff may create fire or explosion hazard. /Organic peroxide type B, solid, temperature controlled; Organic peroxide type D, liquid, temperature controlled/

/GUIDE 148: ORGANIC PEROXIDES (HEAT AND CONTAMINATION SENSITIVE/TEMPERATURE CONTROLLED )/ Health: Fire may produce irritating, corrosive and/or toxic gases. Ingestion or contact (skin, eyes) with substance may cause severe injury or burns. Runoff from fire control or dilution water may cause pollution. /Organic peroxide type B, solid, temperature controlled; Organic peroxide type D, liquid, temperature controlled/

/GUIDE 148: ORGANIC PEROXIDES (HEAT AND CONTAMINATION SENSITIVE/TEMPERATURE CONTROLLED )/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. DO NOT allow the substance to warm up. Obtain liquid nitrogen, dry ice or ice for cooling. If none can be obtained, evacuate the area immediately. /Organic peroxide type B, solid, temperature controlled; Organic peroxide type D, liquid, temperature controlled/

/GUIDE 148: ORGANIC PEROXIDES (HEAT AND CONTAMINATION SENSITIVE/TEMPERATURE CONTROLLED )/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing will only provide limited protection. /Organic peroxide type B, solid, temperature controlled; Organic peroxide type D, liquid, temperature controlled/

For more DOT Emergency Guidelines (Complete) data for DIISOPROPYL PEROXYDICARBONATE (8 total), please visit the HSDB record page.

UN 3112; Organic peroxide Type B, solid, temperature contolled

UN 3115; Organic peroxide Type D, liquid, temperature controlled

IMO 5.2; Organic peroxide Type B and D, liquid and solid, temperature controlled

49 191 76; Isopropyl peroxydicarbonate (not more than 52% in solution)

49 191 75; Isopropyl peroxydicarbonate (technically pure)

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Organic Peroxide Explosive