allylalcohol

H225: Highly Flammable liquid and vapor [Danger Flammable liquids]

H301: Toxic if swallowed [Danger Acute toxicity, oral]

H311: Toxic in contact with skin [Danger Acute toxicity, dermal]

H315: Causes skin irritation [Warning Skin corrosion/irritation]

H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H331: Toxic if inhaled [Danger Acute toxicity, inhalation]

H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

P210, P233, P240, P241, P242, P243, P261, P262, P264, P264+P265, P270, P271, P273, P280, P301+P316, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P370+P378, P391, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

H225 (99.2%): Highly Flammable liquid and vapor [Danger Flammable liquids]

H301+H311+H331 (12.9%): Toxic if swallowed, in contact with skin or if inhaled [Danger Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

H310 (70.5%): Fatal in contact with skin [Danger Acute toxicity, dermal]

H311 (29.2%): Toxic in contact with skin [Danger Acute toxicity, dermal]

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H330 (68.7%): Fatal if inhaled [Danger Acute toxicity, inhalation]

H331 (30.9%): Toxic if inhaled [Danger Acute toxicity, inhalation]

H335 (99.6%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

H400 (99.7%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

H412 (70.3%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P210, P233, P240, P241, P242, P243, P260, P261, P262, P264, P264+P265, P270, P271, P273, P280, P284, P301+P316, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P316, P319, P320, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P370+P378, P391, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 3435 reports by companies from 29 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

H310: Fatal in contact with skin [Danger Acute toxicity, dermal]

H330: Fatal if inhaled [Danger Acute toxicity, inhalation]

H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]

H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]

H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P210, P233, P240, P241, P242, P243, P260, P261, P262, P264, P264+P265, P270, P271, P273, P280, P284, P301+P316, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P308+P316, P316, P319, P320, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P370+P378, P391, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

P210, P233, P240, P241, P242, P243, P260, P261, P262, P264, P264+P265, P270, P271, P280, P284, P301+P316, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P308+P316, P316, P319, P320, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

H305: May be harmful if swallowed and enters airways [Warning Aspiration hazard]

H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]

P210, P233, P240, P241, P242, P243, P260, P262, P264, P264+P265, P270, P271, P280, P284, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P308+P316, P316, P317, P319, P320, P321, P330, P331, P361+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

Fresh air, rest. Refer for medical attention.

Rinse and then wash skin with water and soap. Remove contaminated clothes. Refer for medical attention if skin irritation occurs. Wear protective gloves when administering first aid.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Give one or two glasses of water to drink. Rest. Refer immediately for medical attention.

Warning: Effects may be delayed. Caution is advised.

Signs and Symptoms of Acute Allyl Alcohol Exposure: Signs and symptoms of acute exposure to allyl alcohol may be severe and include eye and skin irritation, pain, burns, and ulceration. Lacrimation (tearing), blurred vision, and photophobia (heightened sensitivity to light) are common; permanent eye damage may occur. Nose and throat irritation, headache, cough, dyspnea (shortness of breath), and hemoptysis (spitting up of blood) may be noted. Nausea, vomiting, and hematuria (bloody urine) may also occur. Liver and kidney damage have been reported in study animals.

Emergency Life-Support Procedures: Acute exposure to allyl alcohol may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:

1. Move victims to fresh air. Emergency personnel should avoid self-exposure to allyl alcohol.

2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.

3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.

4. Transport to a health care facility.

Dermal/Eye Exposure:

1. Remove victims from exposure. Emergency personnel should avoid self- exposure to allyl alcohol.

3. Remove contaminated clothing as soon as possible.

4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.

5. Wash exposed skin areas twice with soap and water.

6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.

7. Transport to a health care facility.

Ingestion Exposure:

1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.

2. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.

3. Vomiting may be induced with syrup of Ipecac. If elapsed time since ingestion of allyl alcohol is unknown or suspected to be greater than 30 minutes, do not induce vomiting and proceed to Step

4. Ipecac should not be administered to children under 6 months of age.Warning: Syrup of Ipecac should be administered only if victims are alert, have an active gag-reflex, and show no signs of impending seizure or coma. If ANY uncertainty exists, proceed to Step

4.The following dosages of Ipecac are recommended: children up to 1 year old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults, 30 mL (1 oz). Ambulate (walk) the victims and give large quantities of water. If vomiting has not occurred after 15 minutes, Ipecac may be readministered. Continue to ambulate and give water to the victims. If vomiting has not occurred within 15 minutes after second administration of Ipecac, administer activated charcoal.

4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.

5. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.

6. Transport to a health care facility. (EPA, 1998)

General First Aid:

· Call 911 or emergency medical service.

· Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.

· Move victim to fresh air if it can be done safely.

· Administer oxygen if breathing is difficult.

· If victim is not breathing:

-- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.

-- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).

-- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.

· Remove and isolate contaminated clothing and shoes.

· For minor skin contact, avoid spreading material on unaffected skin.

· In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.

Water may be ineffective on fire. Cool exposed containers with water. Wear goggles, self-contained breathing apparatus, rubber overclothing, gloves. Isolate for 1/2 mile in all directions if tank car or truck is involved in fire.

Extinguish with dry chemical, alcohol foam, or carbon dioxide. Dike fire control water for later disposal and do not scatter the material. (EPA, 1998)

Use alcohol-resistant foam, water in large amounts, powder, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.

Use water spray, dry chemical, "alcohol resistant" foam, or carbon dioxide. Water may be ineffective. Use water spray to keep fire-exposed containers cool.

If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use "alcohol" foam, dry chemical or carbon dioxide.

Evacuation: If fire becomes uncontrollable or container is exposed to direct flame, consider evacuation of one-third (1/3) mile radius.

Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Advice for firefighters: Wear self-contained breathing apparatus for firefighting if necessary. Further information: Use water spray to cool unopened containers.

Vapor forms explosive mixtures with air. Vapor heavier than air and may travel to a source of ignition & flash back.

Hazardous decomposition products formed under fire conditions. - Carbon oxides

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Keep unauthorized personnel away.

· Stay upwind, uphill and/or upstream.

· Ventilate closed spaces before entering, but only if properly trained and equipped.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

· All equipment used when handling the product must be grounded.

· Do not touch or walk through spilled material.

· Stop leak if you can do it without risk.

· Prevent entry into waterways, sewers, basements or confined areas.

· A vapor-suppressing foam may be used to reduce vapors.

Small Spill

· Absorb with earth, sand or other non-combustible material and transfer to containers for later disposal.

· Use clean, non-sparking tools to collect absorbed material.

Large Spill

· Dike far ahead of liquid spill for later disposal.

· Water spray may reduce vapor, but may not prevent ignition in closed spaces.

Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

SPILL: See ERG Table 1 - Initial Isolation and Protective Action Distances on the UN/NA 1098 datasheet.

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Immediate precautionary measure

· Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

· For highlighted materials: see Table 1 - Initial Isolation and Protective Action Distances.

· For non-highlighted materials: increase the immediate precautionary measure distance, in the downwind direction, as necessary.

· If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Small spill:

- ISOLATE in all directions: 30 m (100 ft)

Large spill:

- ISOLATE in all directions: 60 m (200 ft)

- PROTECT people from downwind during DAY time: 0.2 km (0.1 mi)

- PROTECT people from downwind during NIGHT time: 0.3 km (0.2 mi)

- PROTECT people from downwind during DAY time: 0.8 km (0.5 mi)

- PROTECT people from downwind during NIGHT time: 1.2 km (0.8 mi)

Remove all ignition sources. Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable air tight containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer.

Releases may require isolation or evacuation. Stop or control the leak, if this can be done without undue risk. Use water spray to cool and disperse vapors, protect personnel, and dilute spills to form nonflammable mixtures. Approach release from upwind. Eliminate all ignition sources. Control runoff and isolate discharged material for proper disposal.

If allyl alcohol is spilled or leaked, the following steps should be taken: remove all ignition sources, ventilate area of spill or leak, and for small quantities absorb on paper towels. Evaporate in a safe place, such as a fume hood. Allow sufficient time for evaporating vapors to completely clear the hood ductwork. Burn the paper in a suitable location away from combustible materials. Large quantities can be collected and atomized in a suitable combustible chamber. Allyl alcohol should not be allowed to enter a confined space, such as a sewer, because of the possibility of an explosion.

Environmental considerations: Land spill: Dig a pit, pond, lagoon, or holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Absorb bulk liquids with fly ash, cement powder, or commercial sorbents. Apply "universal" gelling agent to immobilize spill.

Environmental considerations: Water spill: If dissolved, in region of 10 ppm or greater concentration apply activated carbon at ten times the spilled amount. Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates.

For more Cleanup Methods (Complete) data for Allyl alcohol (6 total), please visit the HSDB record page.

Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number P005, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.

Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors.

SMALL SPILL: Absorb with earth, sand or other non-combustible material and transfer to containers for later disposal. Use clean, non-sparking tools to collect absorbed material.

LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2024)

Fireproof. Cool. Separated from strong oxidants and food and feedstuffs. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access.

Separate from oxidizing materials. Store in a dry, cool, well-ventilated location.

Keep tightly closed.

Storage temp: ambient; venting: pressure-vacuum

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Handle and store under inert gas.

· Wear positive pressure self-contained breathing apparatus (SCBA).

· Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE.

· Structural firefighters' protective clothing provides thermal protection but only limited chemical protection.

TIH (Toxic Inhalation Hazard) - Term used to describe gases and volatile liquids that are toxic when inhaled. Some are TIH materials themselves, e.g., chlorine, and some release TIH gases when spilled in water, e.g., chlorosilanes. [ERG 2016].

3.9 [ppm]

AEGL 1: Notable discomfort, irritation, or certain asymptomatic non-sensory effects. However, the effects are not disabling and are transient and reversible upon cessation of exposure (Unit: ppm)

AEGL 2: Irreversible or other serious, long-lasting adverse health effects or an impaired ability to escape (Unit: ppm)

AEGL 3: Life-threatening health effects or death (Unit: ppm)

AEGLs Status: Final

0.09 [ppm]

1.7 [ppm]

13 [ppm]

2 ppm (5 mg/m³)

4 ppm (10 mg/m³)

TWA 2 ppm (5 mg/m3) ST 4 ppm (10 mg/m3) [skin]

2.0 [ppm]

TWA 2 ppm (5 mg/m3) [skin] See Appendix G

20 ppm (NIOSH, 2024)

20.0 [ppm]

Excerpts from Documentation for IDLHs: Human data: Severe eye irritation is reported to result from exposure at 25 ppm [Dunlap et al. 1958].

See: 107186

0.5 [ppm]

8 hr Time Weighted Avg (TWA): 0.5 ppm, skin.

Peak Exposure Recommendation: Transient increases in workers' exposure levels may exceed 3 times the value of the TLV-TWA level for no more than 15 minutes at a time, on no more than 4 occasions spaced 1 hour apart during a workday, and under no circumstances should they exceed 5 times the value of the TLV-TWA level. In addition, the 8-hour TWA is not to be exceeded for an 8-hour work period.

A4; Not classifiable as a human carcinogen.

0.5 ppm as TWA; (skin); A4 (not classifiable as a human carcinogen).

4.8 mg/m

skin absorption (H); carcinogen category: 3

CAUTION: The majority of these products have a very low flash point. Use of water spray when fighting fire may be inefficient.

CAUTION: Methanol (UN1230) will burn with an invisible flame. Use an alternate method of detection (thermal camera, broom handle, etc.)

Small Fire

· Dry chemical, CO2, water spray or alcohol-resistant foam.

Large Fire

· Water spray, fog or alcohol-resistant foam.

· If it can be done safely, move undamaged containers away from the area around the fire.

· Dike runoff from fire control for later disposal.

· Avoid aiming straight or solid streams directly onto the product.

Fire Involving Tanks, Rail Tank Cars or Highway Tanks

· Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.

· Cool containers with flooding quantities of water until well after fire is out.

Allyl alcohol appears as a clear colorless liquid with a mustard-like odor. Flash point 70 °F. Very toxic by inhalation and ingestion. Less dense than water (7.1 lb / gal). Vapors are heavier than air. Prolonged exposure to low concentrations or short exposure to high concentrations may have adverse health effects from inhalation.

Colorless liquid with a pungent, mustard-like odor; [NIOSH]

COLOURLESS LIQUID WITH PUNGENT ODOUR.

Colorless liquid with a pungent, mustard-like odor.

Colorless liquid

Mobile liquid

Pungent, mustard-like odor

206 °F at 760 mmHg (EPA, 1998)

Azeotropic boiling point of 72.3% allyl alcohol and 27.7% water: 88.89 °C

97.00 to 98.00 °C. @ 760.00 mm Hg

97.4 °C @760 [mm Hg]

-200 °F (EPA, 1998)

71.6 °F (EPA, 1998)

70 °F (21 °C) (closed cup)

90 °F (open cup)

70 °F (open cup); 75 °F (closed cup)

21 °C c.c.

Miscible (NIOSH, 2024)

Infinitely soluble in water at 20 °C

Miscible with alcohol, chloroform, ether, petroleum ether

1000 mg/mL at 20 °C

Solubility in water, g/l at 20 °C: >1000 (very soluble)

Miscible

0.854 at 68 °F (EPA, 1998) - Less dense than water; will float

0.8540 at 20 °C/4 °C

Bulk density: 7.11 lb/gal at 20 °C

Liquid heat capacity = 0.493 BTU/lb-F at 70 °F; Liquid thermal conductivity = 1.123 BTU-in/hr-sq ft-F at 77.09 °F; Saturated vapor density = 0.00375 lb/cu ft at 70 °F; Ideal gas heat capacity = 0.327 BTU/lb-F at 70 °F

Relative density (water = 1): 0.9

0.8540 @ 20°C

2 (EPA, 1998) - Heavier than air; will sink (Relative to Air)

2.00 (Air = 1)

Relative vapor density (air = 1): 2.0

23.8 mmHg at 77 °F (EPA, 1998)

25.4 [mmHg]

25.4 mm Hg at 25 °C

Vapor pressure, kPa at 20 °C: 2.5

17 [mm Hg] @20 °C

log Kow = 0.17

Henry's Law constant = 4.99X10-6 atm-cu m/mole at 25 °C

Upon storage for several years allyl alcohol polymerizes and a thick syrup is formed (insol in water, sol in chloroform) which on treatment with ether yields a brittle resinoid mass ... .

Highly flammable. Water soluble.

Alcohols and Polyols

Hydrocarbons, Aliphatic Unsaturated

Polymerizable Compounds

Highly Flammable

Polymerizable

Strong Reducing Agent

ALLYL ALCOHOL presents a dangerous fire and explosion hazard when exposed to heat, flame, or oxidizing agents. Reacts violently or explosively with sulfuric acid, strong bases. Reacts violently with 2,4,6-trichloro-1,3,5-triazine and 2,4,6-tris(bromoamino)-1,3,5-triazine. Reacts with carbon tetrachloride to produce explosively unstable products [Lewis]. Mixing allyl alcohol in equal molar portions with any of the following substances in a closed container caused the temperature and pressure to increase: chlorosulfonic acid, nitric acid, oleum, sulfuric acid [NFPA 491M. 1991].

Incompatible materials: Alkali metals, Oxidizing agents

A reaction between allyl alcohol and carbon tetrachloride produced trichlorobutylene epoxide (oxide) and dichlorobutylene epoxide (oxide), a mixture which during distillation proved to be unstable and detonated in the still.

When aqueous sodium hydroxide was added to a mixture of /2,4,6-trichlorotriazine/ and /allyl/ alcohol at 28 °C instead of the normal 5 °C, a rapidly accelerating reaction led to the rupture of the bursting disc and a gasket, and subsequently to a flash fire and explosion.

Allyl alcohol and tri-n-bromomelamine exploded fifteen minutes after mixing at room temperature.

For more Hazardous Reactivities and Incompatibilities (Complete) data for Allyl alcohol (9 total), please visit the HSDB record page.

Strong oxidizers, acids, carbon tetrachloride [Note: Polymerization may be caused by elevated temperatures, oxidizers, or peroxides.]

IDENTIFICATION AND USE: Allyl alcohol (AA) is a colorless, mobile liquid. Allyl alcohol is used as an intermediate in the pharmaceutical industry. AA is employed in the production of glycerol, diallyl phthalate, diallyl isophthalate, and in the manufacture of acrolein. It has been used as a denaturant for ethanol, a herbicide for ornamentals, celery beds, and soil treatment in uncultivated areas, as a fungicide for tobacco and grass seed, and as a military warfare gas. Its historical use as an insecticide has been abandoned in the United States. HUMAN STUDIES: Absorption through the skin leads to deep muscle pain, presumably due to spasm. AA can produce dermatitis of variable types and degrees results, in addition to first and second-degree burns with vesiculation. Lacrimation, retrobulbar pain, photophobia, and blurring of vision may be associated with exposure to vapors, and corneal injury has been described resulting in temporary blindness. At least three cases of accidental poisoning have been described following acute inhalation exposures to unknown concentrations of allyl alcohol. In each case, these individuals recovered without sequelae. However, oral ingestion of allyl alcohol by a 55-yr-old man resulted in death within 100 min. The concentration of acrolein in blood was 7.2 mg/L. Death was attributed to acrolein-induced acute cardiotoxicity, similar to that previously documented in animal experiments. At least three cases of accidental poisoning have been described following acute inhalation exposures to unknown concentrations of allyl alcohol. In each case, these individuals recovered without sequelae. ANIMAL STUDIES: Animal studies demonstrate AA appears to be oxidized readily in the liver, giving a variety of metabolic products, such as acrolein, acrylic acid, glycidaldehyde, and glyceraldehyde. Among these metabolites, the most reactive metabolite, acrolein may cause hepatotoxicity in the liver. Rats are significantly more sensitive to allyl alcohol-induced liver damage than mice, an effect due to the three-fold greater biotransformation of allyl alcohol to acrolein and acrylic acid in rats than in mice. Middle-aged and older animals are more susceptible to allyl alcohol-induced hepatotoxicity than are young animals. AA was slightly irritating to the skin and caused severe corneal necrosis when applied to the eyes of animals. AA was not a skin sensitizer in guinea pigs. In a repeat dose inhalation toxicity study, male rats were exposed to AA at concentrations of 0, 2.4, 4.7, 12, 47, 95, 142, 237 or 355 mg/cu m for 7 hours/day, 5 days/week for 12 weeks. Histopathology showed that there was slight congestion of the lungs and liver at the dose of 355 mg/cu m. In a repeated dose oral toxicity study, AA had adverse effects on kidney tissues in rats, administered in the drinking water continuously for 15 weeks at or above a level of 100 ppm. A carcinogenicity study was conducted with male and female rats via drinking water (300 mg/L, total dose of 3.2 g) for 106 weeks, followed by observation until natural death (123-132 weeks). The study gave no clear evidence of carcinogenicity in male rats, but there was equivocal evidence of carcinogenicity in the liver of female rats. The in vitro studies, including reverse mutation assays in bacteria (Salmonella typhimurium: positive in T1535 with S9, TA100 without metabolic activation; negative in TA97, TA98, TA100 and TA1535 without metabolic activation), microbial forward mutation and fungal point mutation assays (Streptomyces coelicolor and Aspergillus nidulans, respectively: negative) and gene mutation in mammalian cells (V79 cells: positive) gave conflicting results, while the in vivo studies concerning micronucleus and the dominant lethal assay in rodents gave negative results. Based on these data, there is equivocal evidence that AA may be genotoxic. Litters sired by male rats treated with a dose of 0.86% allyl alcohol 7 days/wk to week 12 and 5 days/wk from week 13 to 33 did not develop any malformations. No adverse reproductive effects were observed. ECOTOXICITY STUDIES: AA was not toxic to fish embryos, or fish cell lines because it needs to be metabolically activated. AA is highly phytotoxic.

Allyl alcohol

5 x 10 ^-3 mg/kg-day

2-Propen-1-ol

Volatile Organic Compound (VOC)

Listed as Allyl alcohol

Smith, C.D. and Nowell, L.H., 2024. Health-Based Screening Levels for evaluating water-quality data (3rd ed.). DOI:10.5066/F71C1TWP

Drug-Induced Liver Injury Severity and Toxicity (DILIst)

allyl alcohol

DILI Positive

DOI:10.1016/j.drudis.2019.09.022

A4; Not classifiable as a human carcinogen.

The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion.

inhalation, skin absorption, ingestion, skin and/or eye contact

Headache. Nausea. Vomiting. Muscle cramps. Muscle pain.

MAY BE ABSORBED! Redness. Pain. See Inhalation.

Redness. Pain.

Abdominal pain. See Inhalation.

Eye irritation, tissue damage; irritation upper respiratory system, skin; pulmonary edema

Eyes, skin, respiratory system

Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

Dermatotoxin - Skin burns.

Lacrimator (Lachrymator) - A substance that irritates the eyes and induces the flow of tears.

Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.

ACGIH Carcinogen - Not Classifiable.

Oral RfD: 0.005 mg/kg/day (UF: 1000, MF: 1)

Allyl Alcohol

4 x 10^-3 mg/kg-day

1 x 10^-3 mg/m^3

PDF Document

Inadequate information to assess carcinogenic potential

SCREEN Current

PPRTV Current

PPRTV Memo

LC50 (rat) = 76 ppm/8hr

LD50 Rabbit percutaneous 89 mg/kg

LD50 Mouse oral 85 mg/kg

LD50 Rat oral 64 mg/kg

LC50 Rat inhalation 165 ppm/4 hr

For more Non-Human Toxicity Values (Complete) data for Allyl alcohol (12 total), please visit the HSDB record page.

EC50; Species: Daphnia magna (Water Flea); Conditions: freshwater, static; Concentration: 4900 ug/L for 24 hr; Effect: behavior equilibrium /formulation/

LC50; Species: Daphnia magna (Water Flea) 1-2 instar larvae; Conditions: freshwater, static, 20 °C, pH 6.5-8.5, dissolved oxygen >40%; Concentration: 250 ug/L for 96 hr /formulation/

LC50; Species: Asellus intermedius (Aquatic Sowbug) juvenile, weight 0.012 g; Conditions: freshwater, static, 20 °C, pH 6.5-8.5, dissolved oxygen >40%; Concentration: 320 ug/L for 96 hr /formulation/

LC50; Species: Gammarus fasciatus (Scud) juvenile, weight 0.007 g; Conditions: freshwater, static, 20 °C, pH 6.5-8.5, dissolved oxygen >40%; Concentration: 4900 ug/L for 96 hr /formulation/

For more Ecotoxicity Values (Complete) data for Allyl alcohol (6 total), please visit the HSDB record page.

/AQUATIC SPECIES/ The OECD test guideline 203 for determination of fish acute toxicity requires substantial numbers of fish and uses death as an apical end point. One potential alternative are fish cell lines; however, several studies indicated that these appear up to several orders of magnitude less sensitive than fish. We developed a fish gill cell line-based (RTgill-W1) assay, using several measures to improve sensitivity. The optimized assay was applied to determine the toxicity of 35 organic chemicals, having a wide range of toxicity to fish, mode of action and physicochemical properties. We found a very good agreement between in vivo and in vitro effective concentrations. For up to 73% of the tested compounds, the difference between the two approaches was less than 5-fold, covering baseline toxicants but as well compounds with presumed specific modes of action, including reactivity, inhibition of acetylcholine esterase or uncoupling of oxidative phosphorylation. Accounting for measured chemical concentrations eliminated two outliers, the hydrophobic 4-decylaniline and the volatile 2,3-dimethyl-1,3-butadiene, with an outlier being operationally defined as a substance showing a more than 10-fold difference between in vivo/in vitro effect concentrations. Few outliers remained. The most striking were allyl alcohol (2700-fold), which likely needs to be metabolically activated, and permethrin (190-fold) and lindane (63-fold), compounds acting, respectively, on sodium and chloride channels in the brain of fish. We discuss further developments of this assay and suggest its use beyond predicting acute toxicity to fish, for example, as part of adverse outcome pathways to replace, reduce, or refine chronic fish tests.

/AQUATIC SPECIES/ The zebrafish embryo toxicity test has been proposed as an alternative for the acute fish toxicity test, which is required by various regulations for environmental risk assessment of chemicals. We investigated the reliability of the embryo test by probing organic industrial chemicals with a wide range of physicochemical properties, toxicities, and modes of toxic action. Moreover, the relevance of using measured versus nominal (intended) exposure concentrations, inclusion of sublethal endpoints, and different exposure durations for the comparability with reported fish acute toxicity was explored. Our results confirm a very strong correlation of zebrafish embryo to fish acute toxicity. When toxicity values were calculated based on measured exposure concentrations, the slope of the type II regression line was 1 and nearly passed through the origin (1 to 1 correlation). Measured concentrations also explained several apparent outliers. Neither prolonged exposure (up to 120 hr) nor consideration of sublethal effects led to a reduced number of outliers. Yet, two types of compounds were less lethal to embryos than to adult fish: a neurotoxic compound acting via sodium channels (permethrin) and a compound requiring metabolic activation (allyl alcohol).

/AQUATIC SPECIES/ Originally designed as an alternative for the acute fish toxicity test according to, e.g., OECD TG 203, the fish embryo test (FET) with the zebrafish (Danio rerio) has been optimized, standardized, and validated during an OECD validation study and adopted as OECD TG 236 as a test to assess toxicity of embryonic forms of fish. ...With respect to bioactivation, the only substance identified so far as not being activated in the zebrafish embryo is allyl alcohol; all other biotransformation processes that have been studied in more detail so far were found to be present, albeit, in some cases, at lower levels than in adult fish...

/AQUATIC SPECIES/ Fish embryos are widely used as an alternative model to study toxicity in vertebrates. Due to their complexity, embryos are believed to more resemble an adult organism than in vitro cellular models. However, concerns have been raised with respect to the embryo's metabolic capacity. We recently identified allyl alcohol, an industrial chemical, to be several orders of magnitude less toxic to zebrafish embryo than to adult zebrafish (embryo LC50=478 mg/L vs. fish LC50=0.28 mg/L). Reports on mammals have indicated that allyl alcohol requires activation by alcohol dehydrogenases (Adh) to form the highly reactive and toxic metabolite acrolein, which shows similar toxicity in zebrafish embryos and adults. To identify if a limited metabolic capacity of embryos indeed can explain the low allyl alcohol sensitivity of zebrafish embryos, we compared the mRNA expression levels of Adh isoenzymes (adh5, adh8a, adh8b and adhfe1) during embryo development to that in adult fish. The greatest difference between embryo and adult fish was found for adh8a and adh8b expression. Therefore, we hypothesized that these genes might be required for allyl alcohol activation. Microinjection of adh8a, but not adh8b mRNA led to a significant increase of allyl alcohol toxicity in embryos similar to levels reported for adults (LC50=0.42 mg/L in adh8a mRNA-injected embryos). Furthermore, GC/MS analysis of adh8a-injected embryos indicated a significant decline of internal allyl alcohol concentrations from 0.23-58 ng/embryo to levels below the limit of detection (< 4.6 ug/L). Injection of neither adh8b nor gfp mRNA had an impact on internal allyl alcohol levels supporting that the increased allyl alcohol toxicity was mediated by an increase in its metabolization. These results underline the necessity to critically consider metabolic activation in the zebrafish embryo. As demonstrated here, mRNA injection is one useful approach to study the role of candidate enzymes involved in metabolization.

/PLANTS/ Allyl alcohol is highly phytotoxic.

3.50e+00

1.50e+01

1.00e-01

4.40e-01

2.10e-01

4.00e+00

4.00e-03

1.00e-04

Volatile

1.11e+05

1.10e+01

4.50e+01

3.10e-01

1.30e+00

6.20e-01

The substance is very toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment.

Allyl alcohol's production and use as an intermediate in the production of glycerol, diallyl phthalate, diallyl isophthalate (monomer and prepolymer), acrolein, epichlorhydrin, pharmaceuticals and other chemicals may result in its release to the environment through various waste streams. Allyl alcohol is reported in the bulb and essential oil of garlic. If released to air, a vapor pressure of 25.4 mm Hg at 25 °C indicates allyl alcohol will exist solely as a vapor in the atmosphere. Vapor-phase allyl alcohol will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals, ozone and night-time nitrate radicals; the half-lives for these reactions in air are estimated to be 7, 19 and 30 hours, respectively. The vapor-phase absorption spectrum of allyl alcohol shows no UV absorption between 290 and 300 nm suggesting that allyl alcohol will not be susceptible to direct photolysis by sunlight. If released to soil, allyl alcohol is expected to have very high mobility based upon an estimated Koc of 2. Volatilization from moist soil surfaces is expected based upon a Henry's Law constant of 4.99X10-6 atm-cu m/mole. Allyl alcohol may volatilize from dry soil surfaces based upon its vapor pressure. Utilizing the Japanese MITI test, 86% of the Theoretical BOD was reached in 2 weeks indicating that biodegradation is an important environmental fate process. Half-lives of 10.2 and 9.5 days at 20 °C were found for allyl alcohol in a Texas soil and a Mississippi soil, respectively. If released into water, allyl alcohol is not expected to adsorb to suspended solids and sediment based upon the estimated Koc. In biodegradation studies, allyl alcohol (25 ppm) was found to degrade 100 and 60% in marine and river water, respectively, after 3 days incubation at 30 °C. Volatilization from water surfaces is expected based upon this compound's Henry's Law constant. Estimated volatilization half-lives for a model river and model lake are 5.7 and 44 days, respectively. An estimated BCF of 3 suggests the potential for bioconcentration in aquatic organisms is low. Hydrolysis is not expected to be an important environmental fate process since this compound lacks functional groups that hydrolyze under environmental conditions (pH 5 to 9). Occupational exposure to allyl alcohol may occur through inhalation and dermal contact with this compound at workplaces where allyl alcohol is produced or used. Monitoring data indicate that the general population may be exposed to allyl alcohol via inhalation of automotive exhaust, tobacco smoke, use of e-cigarettes or ingestion of food (garlic, some seafood, fruit distillates). (SRC)

Allyl alcohol is reported in the bulb and essential oil of garlic (Allium sativum var. sativum)(1).

Allyl alcohol's production and use as an intermediate in the production of glycerol, diallyl phthalate, diallyl isophthalate (monomer and prepolymer), acrolein, epichlorhydrin, pharmaceuticals and other chemicals(1,2) may result in its release to the environment through various waste streams(SRC). Allyl alcohol is a component of tobacco, tobacco smoke and tobacco substitute smoke(3).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 2(SRC), determined from a structure estimation method(2), indicates that allyl alcohol is expected to have very high mobility in soil(SRC). Respective freundlich adsorption coefficients of 4.5X10-3 and 3.3X10-4 in Texas soil and Mississippi soil(3) indicate weak adsorption in soil(SRC). Volatilization of allyl alcohol from moist soil surfaces is expected(SRC) given a Henry's Law constant of 4.99X10-6 atm-cu m/mole(4). Allyl alcohol is expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 25.4 mm Hg at 25 °C(5). A 86% of Theoretical BOD using activated sludge in the Japanese MITI test(6) suggests that biodegradation is an important environmental fate process in soil(SRC). Half-lives of 10.2 and 9.5 days at 20 °C were found for allyl alcohol with Texas soil (pH 7.8, 3.25% organic matter) and Mississippi soil (pH 4.8, <1% organic matter), respectively(3).

AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 2(SRC), determined from a structure estimation method(2), indicates that allyl alcohol is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon a Henry's Law constant of 4.99X10-6 atm-cu m/mole(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 5.7 and 44 days, respectively(SRC). Allyl alcohol is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions(3). According to a classification scheme(5), an estimated BCF of 3(SRC), from its log Kow of 0.17(6) and a regression-derived equation(2), suggests the potential for bioconcentration in aquatic organisms is low. Allyl alcohol, present at 25 ppm, degraded 100 and 60% in marine and river water, respectively, after 3 days incubation at 30 °C(7).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), allyl alcohol, which has a vapor pressure of 25.4 mm Hg(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase allyl alcohol is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals, ozone and night-time nitrate radicals(3-5); the half-lives for these reactions in air are 7, 19 and 30 hours(SRC), calculated from respective rate constants of 5.46X10-11, 1.44X10-17 and 1.3X10-14 cu cm/molecule-sec(3-5). Allyl alcohol in water was found to degrade to carbon dioxide upon exposure to UV light from a high pressure mercury-vapor lamp through a quartz tube(6), but this includes irradiation below 290 nm(SRC). The vapor-phase absorption spectrum of allyl alcohol shows no UV absorption between 290 and 300 nm(7) suggesting that allyl alcohol is not susceptible to direct photolysis by sunlight(SRC).

AEROBIC: Allyl alcohol, present at 100 mg/L, reached 86% of its Theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test, this test rate classifies allyl alcohol as readily biodegradable(1). Following incubation at 20 °C with settled sewage seed, 2.5 ppm of allyl alcohol had degraded to 9.1, 55.0, 78.2 and 81.8% of the Theoretical BOD after 5, 10, 15 and 20 days, respectively(2). In a 5 day BOD test, 81% of the theoretical oxygen demand was observed following incubation of allyl alcohol at 20 °C with a sewage seed(3). Allyl alcohol (25 ppm) was found to degrade 100 and 60% in marine and river water after 3 days of incubation at 30 °C, respectively(4). Half-lives of 10.2 and 9.5 days were found for allyl alcohol with Texas soil (pH 7.8, 3.25% organic matter) and Mississippi soil (pH 4.8, <1% organic matter), respectively, incubated at 20 °C(5).

The rate constant for the vapor-phase reaction of allyl alcohol with photochemically-produced hydroxyl radicals is reported as 5.46X10-11 cu cm/molecule-sec at 25 °C(1). This corresponds to an atmospheric half-life of about 7 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). The rate constant for the vapor-phase reaction of allyl alcohol with ozone has been estimated as 1.44X10-17 cu cm/molecule-sec at 12-22 °C(2). This corresponds to an atmospheric half-life of about 19 hours at an atmospheric concentration of 7X10+11 ozone molecules per cu cm(3). The rate constant for the vapor-phase reaction of allyl alcohol with night-time nitrate radicals (NO3) is 1.3X10-14 cu cm/molecule-sec at 25 °C(4) which corresponds to an atmospheric half-life of about 1.2 days(SRC) at an 12-hour night-time average NO3 radical concentration of 5X10+8 molecules/per cu cm(4). Allyl alcohol is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions(5). Allyl alcohol in water was found to degrade to carbon dioxide upon exposure to UV light from a high pressure mercury-vapor lamp through a quartz tube(6), but this includes irradiation below 290 nm(SRC). The vapor-phase absorption spectrum of allyl alcohol shows no UV absorption between 290 and 300 nm(7) suggesting that allyl alcohol is not susceptible to direct photolysis by sunlight(SRC).

An estimated BCF of 3 was calculated in fish for allyl alcohol(SRC), using a log Kow of 0.17(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low. Uptake of (14)C-allyl alcohol was higher in carrots than in lettuce, and higher in lettuce roots than in lettuce tops in greenhouse experiments(4); no bioaccumulation was observed(4).

Using a structure estimation method based on molecular connectivity indices(1), the Koc of allyl alcohol can be estimated to be 2(SRC). According to a classification scheme(2), this estimated Koc value suggests that allyl alcohol is expected to have very high mobility in soil. Leaching of allyl alcohol from soil surface to deeper layers was found to rank in order of sand > sandy loam > humus sand(3). After 2 days, using 400 mL of water, allyl alcohol leached 100, 83.3 and 96.6% in sand containing 0.51 and 2.89% organic carbon, and sandy loam containing 1.00% organic carbon, respectively(3). Freundlich adsorption coefficients for allyl alcohol in Texas soil (pH 7.8, 3.25% organic matter) and Mississippi soil (pH 4.8, <1% organic matter) were 4.5X10-3 and 3.3X10-4, respectively(4).

The Henry's Law constant for allyl alcohol is 4.99X10-6 atm-cu m/mole(1). This Henry's Law constant indicates that allyl alcohol is expected to volatilize from water surfaces(2). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(2) is estimated as 5.7 days(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(2) is estimated as 44 days(SRC). Allyl alcohol's Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). Allyl alcohol is expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 25.4 mm Hg(3).

SURFACE WATER: Allyl alcohol was found in natural waters at Kitakyushu area, Japan(1).

Allyl alcohol has been detected but not quantified in exhaust gases from internal combustion engines(1).

Allyl alcohol was reported as 1.05% of the total gas emissions from beef cattle over a 48 hour period, it was not detected in swine or poultry gas emissions(1).

Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number P005, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.

SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.

Allyl alcohol is a waste chemical stream constituent which may be subjected to ultimate disposal by controlled incineration.

A good candidate for liquid injection incineration at a temperature range of 650 to 1,600 °C and a residence time of 0.1 to 2 seconds. A good candidate for rotary kiln incineration at a temperature range of 820 to 1,600 °C and residence times of seconds for liquids and gases, and hours for solids. A good candidate for fluidized bed incineration at a temperature range of 450 to 980 °C and residence times of seconds for liquids and gases, and longer for solids.

For more Disposal Methods (Complete) data for Allyl alcohol (8 total), please visit the HSDB record page.

If ... THERE IS NO FIRE, go directly to the Table of Initial Isolation and Protective Action Distances /(see table below)/ ... to obtain initial isolation and protective action distances. IF THERE IS A FIRE, or IF A FIRE IS INVOLVED, go directly to the appropriate guide /(see guide(s) below)/ and use the evacuation information shown under PUBLIC SAFETY.

Table: Table of Initial Isolation and Protective Action Distances for Allyl alcohol ID: 1098 [Table#726]

/GUIDE 131 FLAMMABLE LIQUIDS - TOXIC/ Fire or Explosion: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion and poison hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

/GUIDE 131 FLAMMABLE LIQUIDS - TOXIC/ Health: TOXIC; may be fatal if inhaled, ingested or absorbed through skin. Inhalation or contact with some of these materials will irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

/GUIDE 131 FLAMMABLE LIQUIDS - TOXIC/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. Keep unauthorized personnel away. Stay upwind, uphill and/or upstream. Ventilate closed spaces before entering.

For more DOT Emergency Guidelines (Complete) data for Allyl alcohol (9 total), please visit the HSDB record page.

UN 1098; Allyl alcohol

IMO 6.1; Allyl alcohol

49 074 25; Allyl alcohol

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article. Allyl alcohol is included on the dangerous goods list.

The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials. Allyl alcohol is included on the dangerous goods list.

Poison Inhalation Hazard Flammable Liquid

Unbreakable packaging. Put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs.

UN Hazard Class: 6.1; UN Subsidiary Risks: 3; UN Pack Group: I