Resorcinol

H302: Harmful if swallowed [Warning Acute toxicity, oral]

H315: Causes skin irritation [Warning Skin corrosion/irritation]

H317: May cause an allergic skin reaction [Warning Sensitization, Skin]

H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]

H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

P260, P261, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P351+P338, P308+P316, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P391, P405, and P501 (click each P-code to see the statement)

H302 (> 99.9%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (> 99.9%): Causes skin irritation [Warning Skin corrosion/irritation]

H317 (15.2%): May cause an allergic skin reaction [Warning Sensitization, Skin]

H319 (90.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H370 (15.1%): Causes damage to organs [Danger Specific target organ toxicity, single exposure]

H371 (11.2%): May cause damage to organs [Warning Specific target organ toxicity, single exposure]

H400 (99.9%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

Aggregated GHS information provided per 2727 reports by companies from 51 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

P261, P264+P265, P272, P273, P280, P302+P352, P305+P351+P338, P321, P333+P317, P337+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]

P260, P261, P264, P264+P265, P270, P272, P280, P301+P317, P302+P352, P305+P354+P338, P308+P316, P317, P321, P330, P332+P317, P333+P317, P362+P364, P405, and P501 (click each P-code to see the statement)

H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]

P260, P261, P264, P264+P265, P270, P272, P280, P301+P317, P302+P352, P305+P354+P338, P308+P316, P317, P319, P321, P330, P332+P317, P333+P317, P362+P364, P405, and P501 (click each P-code to see the statement)

H313: May be harmful in contact with skin [Warning Acute toxicity, dermal]

H333: May be harmful if inhaled [Warning Acute toxicity, inhalation]

P260, P261, P264, P264+P265, P270, P272, P280, P301+P317, P302+P317, P302+P352, P304+P317, P305+P354+P338, P308+P316, P317, P319, P321, P330, P332+P317, P333+P317, P362+P364, P405, and P501 (click each P-code to see the statement)

P261, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P351+P338, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P264, P264+P265, P270, P273, P280, P301+P317, P302+P352, P305+P354+P338, P317, P321, P330, P332+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Give a slurry of activated charcoal in water to drink. Refer for medical attention .

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

General First Aid:

· Call 911 or emergency medical service.

· Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.

· Move victim to fresh air if it can be done safely.

· Administer oxygen if breathing is difficult.

· If victim is not breathing:

-- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.

-- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).

-- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.

· Remove and isolate contaminated clothing and shoes.

· For minor skin contact, avoid spreading material on unaffected skin.

· In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.

· For severe burns, immediate medical attention is required.

· Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed.

· Keep victim calm and warm.

· Keep victim under observation.

· For further assistance, contact your local Poison Control Center.

· Note: Basic Life Support (BLS) and Advanced Life Support (ALS) should be done by trained professionals.

Specific First Aid:

· For corrosives, in case of contact, immediately flush skin or eyes with running water for at least 30 minutes. Additional flushing may be required.

· Removal of solidified molten material from skin requires medical assistance.

In Canada, an Emergency Response Assistance Plan (ERAP) may be required for this product. Please consult the shipping paper and/or the "ERAP" section.

(General first aid procedures)

Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.

Skin: Water wash immediately - If this chemical contacts the skin, immediately wash the contaminated skin with water. If this chemical penetrates the clothing, immediately remove the clothing and wash the skin with water. If symptoms occur after washing, get medical attention immediately.

Breathing: Respiratory support

Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately.

Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

SMALL FIRE: Dry chemical, CO2 or water spray.

LARGE FIRE: Dry chemical, CO2, alcohol-resistant foam or water spray. If it can be done safely, move undamaged containers away from the area around the fire. Dike runoff from fire control for later disposal.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. (ERG, 2024)

Use water spray, powder.

If material on fire or involved in fire: Extinguish fire using agent suitable for type of surrounding fire (Material itself does not burn or burns with difficulty). Use water in flooding quantities as fog.

/Use/ water, foam, dry chemical, or carbon dioxide

Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Advice for firefighters: Wear self contained breathing apparatus for fire fighting if necessary.

Water may cause frothing

Special hazards arising from the substance or mixture: Carbon oxides

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Keep unauthorized personnel away.

· Stay upwind, uphill and/or upstream.

· Ventilate closed spaces before entering, but only if properly trained and equipped.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

· Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.

· Stop leak if you can do it without risk.

· Prevent entry into waterways, sewers, basements or confined areas.

· Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers.

· DO NOT GET WATER INSIDE CONTAINERS.

Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Immediate precautionary measure

· Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

· For highlighted materials: see Table 1 - Initial Isolation and Protective Action Distances.

· For non-highlighted materials: increase the immediate precautionary measure distance, in the downwind direction, as necessary.

· If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Personal protection: P2 filter respirator for harmful particles. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Environmental consideration: Water spill: Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates.

Environmental considerations: Land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water.

Accidental Release Measures. Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up: Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.

Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number U201, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.

A good candidate for rotary kiln incineration at a temperature range of 820 to 1,600 °C and residence times of seconds for liquids and gases, and hours for solids. A good candidate for fluidized bed incineration at a temperature range of 450 to 980 °C and residence times of seconds for liquids and gases, and longer for solids.

Chemical Treatability of Resorcinol; Concentration Process: Activated Carbon; Chemical Classification: Phenols; Scale of Study: Batch Flow/Laboratory Scale; Type of Wastewater Used: Pure Compound; Influent Concentration: 100 ppb; Results of Study: 100% reduction; 0% desorbed from carbon by elutriation with solvent (Calgon FS-300 used. Solvent included pentane-acetone, diethyl ether, methylene chloride-acetone, chloroform-acetone and acetone).

Chemical Treatability of Resorcinol; Concentration Process: Resin Adsorption; Chemical Classification: Phenols; Scale of Study: Batch Flow/Laboratory Scale Type of Wastewater Used: Pure Compound; Influent Concentration: 100 ppb; Results of Study: 100% reduction; 60% desorbed from resin by elutriation with solvent (Amberlite XAD-2 used. Solvents included pentane-acetone, diethyl ether, methylene chloride-acetone, chloroform-acetone and acetone).

For more Disposal Methods (Complete) data for RESORCINOL (9 total), please visit the HSDB record page.

SRP: The scientific literature for the use of contact lenses by industrial workers is inconsistent. The benefits or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

Remove contaminated clothing and shoes.

The worker should immediately wash the skin when it becomes contaminated.

Work clothing that becomes wet or significantly contaminated should be removed and replaced.

For more Preventive Measures (Complete) data for RESORCINOL (11 total), please visit the HSDB record page.

Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. (ERG, 2024)

Separated from incompatible materials and food and feedstuffs. See Chemical Dangers.

Separated from incompatible materials and food and feedstuffs.

Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place. Air and light sensitive.

· Wear positive pressure self-contained breathing apparatus (SCBA).

· Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE.

· Structural firefighters' protective clothing provides thermal protection but only limited chemical protection.

90 [mg/m3]

130 [mg/m3]

770 [mg/m3]

10 ppm (45 mg/m³)

20 ppm (90 mg/m³)

TWA 10 ppm (45 mg/m3) ST 20 ppm (90 mg/m3)

none See Appendix G

See: IDLH INDEX

10.0 [ppm]

20.0 [ppm]

8 hr Time Weighted Avg (TWA): 10 ppm; Short Term Exposure Limit (STEL): 20 ppm

A4; Not classifiable as a human carcinogen.

10 ppm as TWA; 20 ppm as STEL; A4 (not classifiable as a human carcinogen).

10 ppm [1992]

20 ppm [1992]

sensitization of skin (SH).

Small Fire

· Dry chemical, CO2 or water spray.

Large Fire

· Dry chemical, CO2, alcohol-resistant foam or water spray.

· If it can be done safely, move undamaged containers away from the area around the fire.

· Dike runoff from fire control for later disposal.

Fire Involving Tanks, Rail Tank Cars or Highway Tanks

· Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.

· Do not get water inside containers.

· Cool containers with flooding quantities of water until well after fire is out.

· Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.

· ALWAYS stay away from tanks in direct contact with flames.

A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20 °C; on spraying or dispersing, however, much faster.

The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated.

Repeated or prolonged contact may cause skin sensitization in rare cases.

Excerpt from NIOSH Pocket Guide for Resorcinol:

Skin: PREVENT SKIN CONTACT - Wear appropriate personal protective clothing to prevent skin contact.

Eyes: PREVENT EYE CONTACT - Wear appropriate eye protection to prevent eye contact.

Wash skin: WHEN CONTAMINATED - The worker should immediately wash the skin when it becomes contaminated.

Remove: WHEN WET OR CONTAMINATED - Work clothing that becomes wet or significantly contaminated should be removed and replaced.

Change: DAILY - Workers whose clothing may have become contaminated should change into uncontaminated clothing before leaving the work premises.

Resorcinol is a very white crystalline solid that becomes pink on exposure to light if not completely pure. Burns although ignition is difficult. Density approximately 1.28 g / cm3. Irritating to skin and eyes. Toxic by skin absorption. Used to make plastics and pharmaceuticals.

Other Solid; Dry Powder; CBI; Large Crystals

White needles, plates, crystals, flakes, or powder with a faint odor. [Note: Turns pink on exposure to air or light, or contact with iron.]; [NIOSH]

WHITE CRYSTALS. TURNS PINK ON EXPOSURE TO AIR AND LIGHT OR ON CONTACT WITH IRON.

White needle-like crystals

White needles, plates, crystals, flakes, or powder with a faint odor. Turns pink on exposure to light if not completely pure.

White needles, plates, crystals, flakes, or powder with a faint odor. [Note: Turns pink on exposure to air or light, or contact with iron.]

Needles from benzene; platelets from water

Rhombic tablets and pyramids

Platelets from ethanol. Very white crystals

For more Color/Form (Complete) data for RESORCINOL (6 total), please visit the HSDB record page.

Faint, characteristic odor

Sweetish taste followed by bitter taste

531 to 536 °F at 760 mmHg (NTP, 1992)

280 °C, but volatilizes at lower temperature and is slightly volatile with steam

178.00 °C. @ 16.00 mm Hg

277-281 °C

276.5 °C @760 [mm Hg]

228 to 232 °F (NTP, 1992)

109.8 °C

Heat of fusion at mp: 21.0 kJ/mol; Heat of vaporization (kJ/mol): 78.2 at 110 °C, 75.2 at 150 °C, 72.0 at 190 °C

228-232 °F

109.4 °C

261 °F (NTP, 1992)

261 °F (Closed cup)

127 °C (261 °F) (Closed cup)

261 °F (127 °C) (Closed cup)

127 °C c.c.

greater than or equal to 100 mg/mL at 65.3 °F (NTP, 1992)

In water, 7.17X10+5 mg/L at 25 °C

1 g dissolves in 0.9 mL water at room temperature, 0.2 mL water at 80 °C

1 g dissolves in 0.9 mL alcohol; freely soluble in ether, glycerol; slightly soluble in chloroform

Very soluble in carbon tetrachloride; soluble in ethanol, ethyl ether; slightly soluble in benzene, chloroform

Soluble in DMSO /dimethyl sulfoxide/, acetone at greater than or equal to 100 mg/mL at 18 °C

717 mg/mL at 25 °C

Solubility in water, g/100ml: 140

soluble in water

moderately soluble (in ethanol)

1.2 at 68 °F (USCG, 1999) - Denser than water; will sink

1.278 g/cu cm at 20 °C

Hygroscopic. Soluble in water.

Phenols and Cresols

RESORCINOL is a weak organic acid. Incompatible with acetanilide, albumin, alkalis, antipyrine, camphor, iron salts, menthol, spirit nitrous ether, and urethane. Can react with oxidizing materials (NTP, 1992). Has a potentially explosive reaction with concentrated nitric acid [Lewis]. Turns pink on contact with iron.

Can react with oxidizing materials

Aquatic reactions: abiotic auto-oxidation at 25 °C: t1/2: 1612 hours at pH 9.0

Acetanilide, albumin, alkalis, antipyrine, camphor, ferric salts, menthol, spirit nitrous ether, strong oxidizers & bases [Note: Hygroscopic (i.e., absorbs moisture from the air)].

Potentially explosive reaction with concentrated nitric acid.

For more Hazardous Reactivities and Incompatibilities (Complete) data for RESORCINOL (6 total), please visit the HSDB record page.

Acetanilide, albumin, alkalis, antipyrine, camphor, ferric salts, menthol, spirit nitrous ether, strong oxidizers & bases [Note: Hygroscopic (i.e., absorbs moisture from the air).]

Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org

IDENTIFICATION AND USE: Resorcinol is a white crystalline compound with a faint odor and bitter-sweet taste. It exists in at least two crystalline modifications. Crystalline resorcinol turns pale red in the presence of light and air and is hygroscopic. It is miscible in water. It is used in tanning, photography; manufacture of resins, resin adhesives, hexylresorcinol, p-aminosalicylic acid, explosives, dyes, tires, rubber products; in cosmetics; dyeing and printing textiles; and as a reagent for zinc. It is not registered for current pesticide use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses. Resorcinol is also a medication, used as an antifungal, antibacterial, mildly keratolytic and local irritant agent. It is a pharmaceutical agent used topically in dermatological treatments such as acne and related skin conditions. It could also be used in combination with the other acne treatment agents such as sulphur. HUMAN EXPOSURE AND TOXICITY: An application of 3-25% solution of resorcinol to skin may cause redness, itching, dermatitis, edema or corrosion of affected area. Potential symptoms of overexposure are irritation of eyes, skin, nose, throat, upper respiratory system; dermatitis; methemoglobinemia, cyanosis, convulsions; restlessness, bluish skin, increased heart rate, dyspnea; dizziness, drowsiness, hypothermia, hemoglobinuria; spleen, kidney, liver changes. ANIMAL STUDIES: Tests of 10% soln on rabbit eyes have caused pain, conjunctival inflammation, and vascularization of cornea. Dry, powdered resorcinol applied to rabbit eyes induced necrosis sufficient to cause perforation of cornea in some and extensive vascularization in others. A subcutaneous injection of 154 mg/kg in rats produced a thyroid disturbance (myxedema and goiter); an effect that did not occur when 50 mg/kg was injected. Resorcinol intake at 1000 mg/L via contaminated drinking water caused no detectable adverse effects on any reproduction or thyroid gland end points in rats. Groups of 10 male and female rats were given 0, 32, 65, 130, 260, or 520 mg/kg resorcinol by gavage 5 days/week for 13 weeks. Most animals given 520 mg/kg died. Daily doses of 65 mg/kg produced increased liver weights, but no other toxic effects were reported. Resorcinol showed no carcinogenic effect when tested by repeated skin application in mice and in 2-year gavage studies in rats and mice. Resorcinol was not mutagenic to Salmonella typhimurium strains TA1535, TA1537, TA98 or TA100 in presence or absence of rat liver postmitochondrial supernatant fraction.

Evaluation: No epidemiological data relevant to the carcinogenicity of resorcinol were available. There is inadequate evidence in experimental animals for the carcinogenicity of resorcinol. Overall evaluation: Resorcinol is not classifiable as to its carcinogenicity to humans (Group 3).

A4; Not classifiable as a human carcinogen.

Resorcinol

Group 3: Not classifiable as to its carcinogenicity to humans

Volume 15: (1977) Some Fumigants, the Herbicides 2,4-D and 2,4,5-T, Chlorinated Dibenzodioxins and Miscellaneous Industrial Chemicals

Volume Sup 7: Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1 to 42, 1987; 440 pages; ISBN 92-832-1411-0 (out of print)

Volume 71: (1999) Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide (Part 1, Part 2, Part 3)

TR-403: Toxicology and Carcinogenesis Studies of Resorcinol (CASRN 108-46-3) in F344 Rats and B6C3F1 Mice (Gavage Studies) (1992 )

03/11/91

No Evidence

Under the conditions of these 2-year gavage studies, there was no evidence of carcinogenic activity of resorcinol in male F344/N rats given 112 or 225 mg/kg or female F344/N rats given 50, 100, or 150 mg/kg. There was no evidence of carcinogenic activity of resorcinol in male or female B6C3F1 mice given 112 or 225 mg/kg.

Clinical signs suggestive of a chemical-related effect on the central nervous system, including ataxia, recumbency, and tremors, were observed in rats and mice in the 2-year studies.

3, not classifiable as to its carcinogenicity to humans. (L135)

The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

inhalation, ingestion, skin and/or eye contact

Abdominal pain. Blue lips, fingernails and skin. Confusion. Convulsions. Cough. Dizziness. Headache. Nausea. Sore throat. Unconsciousness.

Redness. Pain.

See Inhalation.

irritation eyes, skin, nose, throat, upper respiratory system; methemoglobinemia; cyanosis, convulsions; restlessness, bluish skin, increased heart rate, dyspnea (breathing difficulty); dizziness, drowsiness, hypothermia, hematuria (blood in the urine); spleen, kidney, liver changes; dermatitis

Eyes, skin, respiratory system, cardiovascular system, central nervous system, blood, spleen, liver, kidneys

Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

Methemoglobinemia - The presence of increased methemoglobin in the blood; the compound is classified as secondary toxic effect

Dermatotoxin - Skin burns.

Skin Sensitizer - An agent that can induce an allergic reaction in the skin.

ACGIH Carcinogen - Not Classifiable.

LCLo (rat) = 160 mg/m3/1h

LD50 Rabbit dermal 3360 mg/kg

LD50 Rat oral 301 mg/kg

LD50 Mouse ip 215 mg/kg

LD50 Mouse subcutaneous 213 mg/kg

The micronucleus test using mouse bone marrow polychromatic erythrocytes was used to study the extent of which benzo(a)pyrene (BP) mutagenicity was inhibited by mixtures of simple phenols (resorcinol & pyrogallol) with & without the complex hindered-phenol antioxidant ... 2,6-di-tert-butyl-4-methylphenol. Mixtures of these phenolic compds inhibited benzo(a)pyrene mutagenicity more effectively than did the individual constituents. One can assume that the simple phenols regenerated in the presence of 2,6-di-tert-butyl-4-methylphenol from the tissue-oxidized forms incr the formation of detoxified or less mutagenic metabolites of benzo(a)pyrene.

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Phenols and related compounds/

Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist respirations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Administer activated charcoal ... . Do not use emetics ... . Cover skin burns with dry, sterile dressings after decontamination ... . Maintain body temperature. /Phenols and related compounds/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Administer 1% solution methylene blue if patient is sympotomatic with severe hypoxia, cyanosis, and cardiac compromise not responding to oxygen. Direct physician order only ... . Treat seizures with diazepam (Valium) or lorazepam (Ativan) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Phenols and related compounds/

Emergency and supportive measures. 1. Maintain an open airway and assist ventilation if necessary. 2. Treat coma, seizures, hypotension, and arrhythmias if they occur. 3. If corrosive injury to the GI tract is suspected, consult a gastroenterologist for possible endoscopy. /Phenols and related compounds/

For more Antidote and Emergency Treatment (Complete) data for RESORCINOL (7 total), please visit the HSDB record page.

/SIGNS AND SYMPTOMS/ application of 3-25% soln of resorcinol to skin may cause redness, itching, dermatitis, edema or corrosion of affected area. Ingestion of 8 g ... by child resulted in hypothermia, hypotension, decr respiration, tremors, icterus & hemoglobinuria ...

/SIGNS AND SYMPTOMS/ Pathology reported for humans includes anemia, marked siderosis of the spleen and marked tubular injury in the kidney, fatty changes and edema of the liver, degenerative changes in the kidney, fatty changes of the heart muscle, moderate enlargement and pigmentations of the spleen, and edema and emphysema of the lungs.

LC50; Species: Pimephales promelas (fathead minnow); Concentration: 88.6 mg/L for 24 hr /Conditions of bioassay not specified/

LC50; Species: Pimephales promelas (fathead minnow); Concentration: 72.6 mg/L for 48 hr /Conditions of bioassay not specified/

LC50; Species: Pimephales promelas (fathead minnow); Concentration: 53.4 mg/L for 96 hr /Conditions of bioassay not specified/

LC50; Species: Palaemonetes pugio (grass shrimp); Concentration: 170 mg/L for 24 hr /Conditions of bioassay not specified/

For more Ecotoxicity Values (Complete) data for RESORCINOL (8 total), please visit the HSDB record page.

/AQUATIC SPECIES/ Sea bass (Dicentrarchus labrax) were injected intraperitoneally once (single dose) or three times (fractionated dose) with phenol or OH-phenols (hydroquinone, resorcinol, and pyrocatechol). On the basis of the lethal doses, OH-phenols were more toxic than phenol, and pyrocatechol was the most powerful compound. Hematological, metabolic and antioxidant blood parameters were measured 3 days after the end of the treatment. Metabolic variations as specific effects on erythrocytes were revealed and differences between single and fractionated doses were observed. OH-phenols-treated fish showed disorders in the metabolic toxicity indicators as hypoglycemia, low blood urea nitrogen level (BUN) and decrease of alkaline phosphatase activity (ALP).

The substance is harmful to aquatic organisms.

Resorcinol's production and use as chemical intermediate, in the production of sunscreen preparations for the skin, production of dyes, manufacture of special pharmaceuticals, manufacturing adhesives, explosives, tires and rubber products may result in its release to the environment through various waste streams. Resorcinol is present in a few plants. If released to air, a vapor pressure of 4.89X10-4 mm Hg at 25 °C indicates resorcinol will exist in both the vapor and particulate phases in the atmosphere. Vapor-phase resorcinol will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 1 hour. Particulate-phase resorcinol will be removed from the atmosphere by wet and dry deposition. As a class, phenols react relatively rapidly in sunlit natural water via reaction with photochemically produced hydroxyl radicals and peroxy radicals. Therefore, resorcinol may be susceptible to direct photolysis by sunlight. If released to soil, resorcinol is expected to have very high mobility based upon a Koc of 10.6. The pKa1 of resorcinol is 9.30, indicating that this compound will exist partially in the anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts. Volatilization from moist soil surfaces is not expected to be an important fate process based upon an estimated Henry's Law constant of 9.9X10-11 atm-cu m/mole. Resorcinol is not expected may volatilize from dry soil surfaces based upon its vapor pressure. Utilizing the Japanese MITI test, 100% of the Theoretical BOD was reached in 2 weeks indicating that biodegradation is an important environmental fate process in soil and water. If released into water, resorcinol is not expected to adsorb to suspended solids and sediment based upon the Koc. Volatilization from water surfaces is not expected to be an important fate process based upon this compound's estimated Henry's Law constant. An estimated BCF of 3 suggests the potential for bioconcentration in aquatic organisms is low. Hydrolysis is not expected to be an important environmental fate process since this compound lacks functional groups that hydrolyze under environmental conditions (pH 5 to 9). Occupational exposure to resorcinol may occur through inhalation and dermal contact with this compound at workplaces where resorcinol is produced or used. Monitoring and use data indicate that the general population may be exposed to resorcinol via inhalation of wood or cigarette smoke and dermal contact with consumer products containing resorcinol. (SRC)

Resorcinol was detected, not quantified in the wood of Morus alba L. (Moraceae), white mulberry(1). It is also been found in broad bean (Vicia faba), honey mushroom (Armillaria mellea), and in exudates of seedlings of the yellow pond lilly (Nuphar lutea). Resorcinol was detected in extracts of tobacco leaves(2).

Resorcinol's production and use in a chemical intermediate for production of m-aminophenol, production of light stabilizers for plastics, production of sunscreen preparations for the skin, production of dyes (fluorescein, eosin), manufacture of special pharmaceuticals (e.g. acne preparations)(1); in tanning; manufacturing resins, resin adhesives, hexylresorcinol, p-amino salicyclic acid, explosives, tires, rubber products; in cosmetics; dyeing and printing textiles; as a reagent for zinc(2) and hair dyes(3) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Based on a classification scheme(1), a Koc value of 10.36(2) indicates that resorcinol is expected to have very high mobility in soil(SRC). The pKa1 of resorcinol is 9.30(3), indicating that this compound will exist partially in the anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(4). Volatilization of resorcinol from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 9.9X10-11 atm-cu m/mole(SRC), based upon its vapor pressure, 4.89X10-4 mm Hg(5), and water solubility, 7.17X10+5 mg/L(6). Resorcinol is not expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(5). Utilizing the Japanese MITI test, 100% of the Theoretical BOD was reached in 2 weeks(7) indicating that biodegradation is an important environmental fate process in soil(SRC).

AQUATIC FATE: Based on a classification scheme(1), a Koc value of 10.36(2) indicates that resorcinol is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 9.9X10-11 atm-cu m/mole(SRC), derived from its vapor pressure, 4.89X10-4 mm Hg(4), and water solubility, 7.17X10+5 mg/L(5). As a class, phenols react relatively rapidly in sunlit natural water via reaction with photochemically produced hydroxyl radicals and peroxy radicals(6). According to a classification scheme(7), an estimated BCF of 3(SRC), from its log Kow of 0.80(8) and a regression-derived equation(9), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Utilizing the Japanese MITI test, 100% of the Theoretical BOD was reached in 2 weeks(10) indicating that biodegradation is an important environmental fate process in water(SRC).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), resorcinol, which has a vapor pressure of 4.89X10-4 mm Hg at 25 °C(2), will exist in both the vapor and particulate phases in the ambient atmosphere. Vapor-phase resorcinol is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 1 hour(SRC), calculated from its rate constant of 2.0X10-10 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). The vapor-phase reaction of resorcinol with nitrate radicals may be an important atmospheric removal process in urban areas at night(4). Particulate-phase resorcinol may be removed from the air by wet and dry deposition(SRC). As a class, phenols react relatively rapidly in sunlit natural water via reaction with photochemically produced hydroxyl radicals and peroxy radicals(5). Therefore, resorcinol may be susceptible to direct photolysis by sunlight(SRC).

AEROBIC: Resorcinol, present at 100 mg/L, reached 100% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(1,-3). Complete degradation of resorcinol occurred in 8 days (as determined by a 100% UV absorbancy loss) in a mineral salts medium using a silt loam soil inocula(4). A 5-day 61% theoretical BOD was measured using a sewage inocula(5). A 95% degradation was observed over a 0.4-day incubation period using a Warburg respirometer and an acclimated activated sludge inocula(6). A 6-day 21% theoretical BOD was observed using a Warburg respirometer and an activated sludge acclimated to aniline(7). A 12-hr theoretical BOD of 33-39% was observed using a Warburg respirometer and activated sludge acclimated to either phenol, catechol, or benzoic acid(8). A 5-day COD removal of 90% was measured in an activated sludge system(9). The half-life of resorcinol in an aerobic screening test ranged from 0.16 to 0.24 days using activated sludge acclimated to cresols(10). Half-lives of 0.5 and 4.5 hours were determined for initial concentrations of 20 and 120 ppm resorcinol, respectively, in a treatment plant simulation study over a 1-hr incubation period using inoculum from a coke wastewater treatment plant(11). Degradation of 95% in 1 day and 90% in 8 days was observed in a biological treatment simulation using activated sludge and initial concns of 138 and 500 ppm, respectively(12). Using a Warburg respirometer and a mixed-culture of bacteria adapted to phenol, 95% of initial resorcinol was degraded in 1 to 2 days(13). Resorcinol, present at 2 mg/L, reached 68.6% of its theoretical BOD in 5 days, using 150 mL of river water in the river die-away test. The source of river water inoculum was the Songhua River, Jilan Province, China, which is contaminated with substituted benzenes(14).

ANAEROBIC: Resorcinol was readily degraded (95% utilization based on TOC) in an anaerobic reactor(1). A 98% of theoretical methane formation was observed in an anaerobic-water screening test using inoculum from one waste treatment facility, but no methane formation was observed using inoculum from a second treatment facility(2).The degradation of resorcinol was examined using anaerobic denitrifying enrichments established in sediments from an estuarine tidal strait in New Jersey(4). Resorcinol half-lives were found to range between 1 and 7 days(4). Activated sludge from an oxidation ditch treating domestic wastewater was separately acclimated to mixed feeds containing m-nitrobenzene sulphonate and resorcinol, m-aminophenol and resorcinol, and catechol and resorcinol(5). Biodegradation half-lives for the three separate feed mixtures were approximately 9 hours, 2.5 hours, and 10 hours, respectively(5). The biodegradation of resorcinol was studied in an upflow anaerobic filter(6). Biodegradation half-lives were found to range from 30 to 250 days, varying with substrate organic loadings(6).

The rate constant for the vapor-phase reaction of resorcinol with photochemically-produced hydroxyl radicals has been estimated as 2.0X10-10 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 1 hour at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). The vapor-phase reaction of resorcinol with nitrate radicals may be an important atmospheric removal process in urban areas at night(2), but the rate of this reaction is not known. Resorcinol is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions(3). As a class, phenols react relatively rapidly in sunlit natural water via reaction with photochemically produced hydroxyl radicals and peroxy radicals(4); typical half-lives for hydroxyl radical and peroxy radical reaction are on the order of 100 and 19.2 hours of sunlight, respectively(4). Resorcinol does not absorb UV light at wavelengths above 295 nm at low concentrations in methanol or acidic aqueous solution(5). However, in dilute alkaline solutions, resorcinol does absorb UV light above 295 nm(5). Resorcinol has a pKa of 9.15(6) which indicates that it will increasingly dissociate with an increase of pH. These data suggest that direct photolysis in environmental waters will not occur under acidic conditions, but may potentially occur in alkaline waters(SRC). Resorcinol crystals acquire a pink tint when exposed to light and air(7).

An estimated BCF of 3 was calculated in fish for resorcinol(SRC), using a log Kow of 0.80(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

The Koc of resorcinol in a clay loam soil from the Michigan State University Soils Research Farm was measured to be 10.36(1). According to a classification scheme(2), this estimated Koc value suggests that resorcinol is expected to have very high mobility in soil. The pKa1 of resorcinol is 9.30(3), indicating that this compound will exist partially in the anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(4).

The Henry's Law constant for resorcinol is estimated as 9.9X10-11 atm-cu m/mole(SRC) derived from its vapor pressure, 4.89X10-4 mm Hg(1), and water solubility, 7.17X10+5 mg/L(2). This Henry's Law constant indicates that resorcinol is expected to be essentially nonvolatile from water and moist soil surfaces(3). Resorcinol is not expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(1).

GROUND WATER: Resorcinol was found as a pollutant in filtered ground water at an unspecified waste treatment plant(1).

SURFACE WATER: Resorcinol was found as a pollutant in filtered surface water at an unspecified waste treatment plant(1).

The concentration of resorcinol in the condensate water from a coal gasification facility in Grand Forks, ND ranged from not detected (no analytical detection limit reported) to 60 ppm between Jun 1980 and Apr 1982(1). A resorcinol level of 1000 ppm was detected in wastewater from a synthetic coal conversion process(2). Resorcinol has been found in effluents associated with coal gasification and conversion, coal-tar production and shale oil processing(3).

Characterization of particulate emissions from fireplace combustion of the most prevalent woods found in the United States revealed the presence of resorcinol. Smoke samples were collected during a pyrolysis experiment and analyzed by GC/MS. The concentrations were reported in mg/g pyrolysis product/wood weight as follows: 2.343 yellow poplar (Liriodendron tulipifera); 1.225, white ash (Faxinus americana); 1.288, sweetgum (Liquidambar styraciflua); 3.352, mockernut hickory (Carya tomentosa); 0.661, loblolly pine (Pinus taeda); detected, not quantified, slash pine (Pinus elliottii)(1). Resorcinol was present at 11.6, 21.4 and 17.4 mg/kg dry wood burned in open, half-closed, and closed airflow emissions, respectively, using woodheaters commonly used in central Australia. Higher burn rates (open fair flow) producing much less particle mass per kg wood burned than the low burn rates (closed airflow). Wood used was White gum (Eucalyptus viminalis)(2).

Resorcinol is a component of cigarette smoke(1).

According to the 2012 TSCA Inventory Update Reporting data, the number of persons reasonably likely to be exposed in the industrial manufacturing, processing, and use of resorcinol is 499 with some manufacturers withholding the information as confidential business information; therefore, the data may be greatly underestimated(1).

NIOSH (NOES Survey 1981-1983) has statistically estimated that 100,792 workers (56,465 of these were female) were potentially exposed to resorcinol in the US(1). Occupational exposure to resorcinol may occur through inhalation and dermal contact with this compound at workplaces where resorcinol is produced or used. Monitoring and use data indicate that the general population may be exposed to resorcinol via inhalation of wood or cigarette smoke and dermal contact with consumer products containing resorcinol(SRC).

Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number U201, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.

A good candidate for rotary kiln incineration at a temperature range of 820 to 1,600 °C and residence times of seconds for liquids and gases, and hours for solids. A good candidate for fluidized bed incineration at a temperature range of 450 to 980 °C and residence times of seconds for liquids and gases, and longer for solids.

Chemical Treatability of Resorcinol; Concentration Process: Activated Carbon; Chemical Classification: Phenols; Scale of Study: Batch Flow/Laboratory Scale; Type of Wastewater Used: Pure Compound; Influent Concentration: 100 ppb; Results of Study: 100% reduction; 0% desorbed from carbon by elutriation with solvent (Calgon FS-300 used. Solvent included pentane-acetone, diethyl ether, methylene chloride-acetone, chloroform-acetone and acetone).

Chemical Treatability of Resorcinol; Concentration Process: Resin Adsorption; Chemical Classification: Phenols; Scale of Study: Batch Flow/Laboratory Scale Type of Wastewater Used: Pure Compound; Influent Concentration: 100 ppb; Results of Study: 100% reduction; 60% desorbed from resin by elutriation with solvent (Amberlite XAD-2 used. Solvents included pentane-acetone, diethyl ether, methylene chloride-acetone, chloroform-acetone and acetone).

For more Disposal Methods (Complete) data for RESORCINOL (9 total), please visit the HSDB record page.

/GUIDE 153: SUBSTANCES - TOXIC and/or CORROSIVE (Combustible)/ Fire or Explosion: Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

/GUIDE 153: SUBSTANCES - TOXIC and/or CORROSIVE (Combustible)/ Health: TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

/GUIDE 153: SUBSTANCES - TOXIC and/or CORROSIVE (Combustible)/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate enclosed areas.

/GUIDE 153: SUBSTANCES - TOXIC and/or CORROSIVE (Combustible)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.

For more DOT Emergency Guidelines (Complete) data for RESORCINOL (8 total), please visit the HSDB record page.

UN 2876; Resorcinol

IMO 6.1; Resorcinol

49 667 74; Resorcinol

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Do not transport with food and feedstuffs.

Symbol: Xn, N; R: 22-36/38-50; S: (2)-26-61

UN Hazard Class: 6.1; UN Pack Group: III