2-methyl-3-butyn-2-ol

This chemical does not meet GHS hazard criteria for 4.8% (24 of 500) of reports.

H225 (62.8%): Highly Flammable liquid and vapor [Danger Flammable liquids]

H226 (30.2%): Flammable liquid and vapor [Warning Flammable liquids]

H302 (94.2%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (12%): Causes skin irritation [Warning Skin corrosion/irritation]

H318 (77.8%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

H319 (16.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H335 (33%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

H336 (13.2%): May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]

H361 (27.8%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

P203, P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P317, P318, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 500 reports by companies from 20 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria per 24 of 500 reports by companies.

There are 19 notifications provided by 476 of 500 reports by companies with hazard statement code(s).

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

H225: Highly Flammable liquid and vapor [Danger Flammable liquids]

H302: Harmful if swallowed [Warning Acute toxicity, oral]

H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]

H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]

P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P317, P303+P361+P353, P304+P340, P305+P354+P338, P317, P319, P330, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Fresh air, rest.

Rinse skin with plenty of water or shower.

Rinse with plenty of water (remove contact lenses if easily possible).

Rinse mouth.

Get medical attention.

INHALATION: Remove to fresh air. If breathing is difficult, give oxygen.

EYES: Flush with water for at least 15 min., lifting lids occasionally.

SKIN: Remove contaminated clothing and shoes. Flush with water. (USCG, 1999)

Fire Extinguishing Agents Not to Be Used: Water.

Fire Extinguishing Agents: Dry chemical, alcohol foam or carbon dioxide. (USCG, 1999)

Use carbon dioxide, foam, dry powder. NO water. In case of fire: keep drums, etc., cool by spraying with water. NO direct contact of the substance with water.

Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

LARGE SPILL: Consider initial downwind evacuation for at least 300 meters (1000 feet).

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer.

Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean, non-sparking tools to collect absorbed material.

LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2024)

Fireproof. Separated from strong oxidants, acids and copper. Cool.

No indication can be given about the rate at which a harmful concentration of this substance in the air is reached.

The substance is irritating to the eyes.

Wear full impervious protective clothing and approved respirator. Where splashing is possible wear full face shield or chemical safety goggles. Use approved respirator to protect against vapors. (USCG, 1999)

If powder: NO open flames, NO sparks, and NO smoking. Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.

Use ventilation.

Protective gloves.

Wear safety goggles.

Do not eat, drink, or smoke during work.

2-methyl-2-hydroxy-3-butyne is a colorless to straw yellow liquid. (USCG, 1999)

Liquid; mp = 2.6 deg C; [Merck Index] Colorless liquid; [Alfa Aesar MSDS]

COLOURLESS LIQUID.

219.2 to 221 °F at 760 mmHg (USCG, 1999)

104-105 °C

36.7 °F (USCG, 1999)

77 °F (USCG, 1999)

20 °C c.c.

Solubility in water: miscible

0.8672 (USCG, 1999) - Less dense than water; will float

Density (gas): 0.9 kg/m³

Relative density of the vapour/air-mixture at 20 °C (air = 1): 1.04

Relative vapor density (air = 1): 2.9

16.0 [mmHg]

Vapor pressure, kPa at 20 °C: 2

Boiling point

Heat of sublimation

Optical coefficient

Refractive index

Thermal expansion coefficient

Vapor pressure

Viscosity

Other Classes -> Alcohols and Polyols, Other

Highly flammable.

Alcohols and Polyols

Alkynes, with Acetylenic Hydrogen

Highly Flammable

2-METHYL-2-HYDROXY-3-BUTYNE is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.

The substance can be absorbed into the body by ingestion.

Redness. Pain.

Dizziness.

Neurotoxin - Acute solvent syndrome

LC50 (mouse) = 2,000 mg/m3

Flammable Liquid

UN Hazard Class: 3; UN Pack Group: II