Zinc Peroxide

This chemical does not meet GHS hazard criteria for 1% (1 of 100) of reports.

H271 (94%): May cause fire or explosion; strong Oxidizer [Danger Oxidizing liquids; Oxidizing solids]

H315 (95%): Causes skin irritation [Warning Skin corrosion/irritation]

H319 (95%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P210, P220, P264, P264+P265, P280, P283, P302+P352, P305+P351+P338, P306+P360, P321, P332+P317, P337+P317, P362+P364, P370+P378, P371+P380+P375, P420, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 100 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria per 1 of 100 reports by companies.

There are 6 notifications provided by 99 of 100 reports by companies with hazard statement code(s).

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

H272: May intensify fire; oxidizer [Danger Oxidizing liquids; Oxidizing solids]

P210, P220, P280, P370+P378, and P501 (click each P-code to see the statement)

H302: Harmful if swallowed [Warning Acute toxicity, oral]

H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P260, P261, P264, P270, P271, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P319, P321, P330, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Excerpt from ERG Guide 143 [Oxidizers (Unstable)]:

Refer to the "General First Aid" section. Specific First Aid: Contaminated clothing may be a fire risk when dry. (ERG, 2024)

General First Aid:

· Call 911 or emergency medical service.

· Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.

· Move victim to fresh air if it can be done safely.

· Administer oxygen if breathing is difficult.

· If victim is not breathing:

-- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.

-- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).

-- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.

· Remove and isolate contaminated clothing and shoes.

· For minor skin contact, avoid spreading material on unaffected skin.

· In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.

· For severe burns, immediate medical attention is required.

· Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed.

· Keep victim calm and warm.

· Keep victim under observation.

· For further assistance, contact your local Poison Control Center.

· Note: Basic Life Support (BLS) and Advanced Life Support (ALS) should be done by trained professionals.

Specific First Aid:

· Contaminated clothing may be a fire risk when dry.

In Canada, an Emergency Response Assistance Plan (ERAP) may be required for this product. Please consult the shipping paper and/or the "ERAP" section.

Excerpt from ERG Guide 143 [Oxidizers (Unstable)]:

SMALL FIRE: Use water. Do not use dry chemicals or foams. CO2 or Halon® may provide limited control.

LARGE FIRE: Flood fire area with water from a distance. Do not move cargo or vehicle if cargo has been exposed to heat. If it can be done safely, move undamaged containers away from the area around the fire. Do not get water inside containers: a violent reaction may occur.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Cool containers with flooding quantities of water until well after fire is out. Dike runoff from fire control for later disposal. ALWAYS stay away from tanks in direct contact with flames. For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn. (ERG, 2024)

If material on fire or involved in fire: Flood with water. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. If fire becomes uncontrollable consider evacuation of one-half mile.

Wear positive pressure self-contained breathing apparatus when fighting fires involving this material.

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Keep unauthorized personnel away.

· Stay upwind, uphill and/or upstream.

· Ventilate closed spaces before entering, but only if properly trained and equipped.

· Keep combustibles (wood, paper, oil, etc.) away from spilled material.

· Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.

· Use water spray to reduce vapors or divert vapor cloud drift.

· Prevent entry into waterways, sewers, basements or confined areas.

Small Spill

· Flush area with large amounts of water.

Large Spill

· DO NOT CLEAN-UP OR DISPOSE OF, EXCEPT UNDER SUPERVISION OF A SPECIALIST.

Excerpt from ERG Guide 143 [Oxidizers (Unstable)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Immediate precautionary measure

· Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

· For highlighted materials: see Table 1 - Initial Isolation and Protective Action Distances.

· For non-highlighted materials: increase the immediate precautionary measure distance, in the downwind direction, as necessary.

· If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Avoid breathing dusts. Wash away any material which may have contacted the body with copious amounts of water or soap and water.

Excerpt from ERG Guide 143 [Oxidizers (Unstable)]:

Keep combustibles (wood, paper, oil, etc.) away from spilled material. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Use water spray to reduce vapors or divert vapor cloud drift. Prevent entry into waterways, sewers, basements or confined areas.

SMALL SPILL: Flush area with large amounts of water.

LARGE SPILL: DO NOT CLEAN-UP OR DISPOSE OF, EXCEPT UNDER SUPERVISION OF A SPECIALIST. (ERG, 2024)

· Wear positive pressure self-contained breathing apparatus (SCBA).

· Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE.

· Structural firefighters' protective clothing provides thermal protection but only limited chemical protection.

0.1 [mg/m3] (respirable fraction), 2 mg/m3 (inhalable fraction) for Zn inorg. cmpnds[German Research Foundation (DFG)]

Intermediate Oral: 0.3 mg/kg/day (L134)

Chronic Oral: 0.3 mg/kg/day (L134)

Small Fire

· Use water. Do not use dry chemicals or foams. CO2 or Halon® may provide limited control.

Large Fire

· Flood fire area with water from a distance.

· Do not move cargo or vehicle if cargo has been exposed to heat.

· If it can be done safely, move undamaged containers away from the area around the fire.

· Do not get water inside containers: a violent reaction may occur.

Fire Involving Tanks, Rail Tank Cars or Highway Tanks

· Cool containers with flooding quantities of water until well after fire is out.

· Dike runoff from fire control for later disposal.

· ALWAYS stay away from tanks in direct contact with flames.

· For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn.

Excerpt from ERG Guide 143 [Oxidizers (Unstable)]:

Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE. Structural firefighters' protective clothing provides thermal protection but only limited chemical protection. (ERG, 2024)

Zinc peroxide appears as a white powder.

White to yellowish-white odorless solid; [Merck Index] Light-yellow odorless powder; [MSDSonline]

WHITE TO YELLOWISH-WHITE POWDER

Odorless

INSOL IN WATER; SOL IN DIL ACIDS

Insol in organic solvents

1.57 g/cu cm

Yellowish powder; density: 3.00 + or - 0.08; loses oxygen in vacuum; slightly decomp in cold water; decomp in hot water; decomposes in ether, alcohol, acetone; /Zinc peroxide hemihydrate/

Shelf-life 21 days. /Zinc peroxide cream/

Finely divided powder ... decomposes rapidly at 150 deg.

Decomposes to zinc oxide and oxygen above 150 °C. Decomposes explosively at 190-212 °C.

STRONG OXIDIZING AGENT; DECOMPOSES IN ACIDS, ALCOHOL, ACETONE

DECOMPOSES ABOVE 150 °C; GRADUALLY DECOMPOSED BY WATER; LIBERATES HYDROGEN PEROXIDE IN DIL ACIDS

crystal structure

positional coordinate

space group

enthalpy change

phase diagram

unit cell parameter

heat capacity

thermal capacity

peritectic temperature

geothermal energy content

thermal diffusivity

phase transition

X-ray diffraction

atomic environment

unit cell axes

thermal conductivity

eutectic transformation

Metals -> Peroxides, Metal

Reactive agents - 3rd degree

Oxidising

Slowly decomposed by water.

Oxidizing Agents, Strong

Explosive

Strong Oxidizing Agent

ZINC PEROXIDE dissolves in dilute acid, liberating hydrogen peroxide [Merck 11th ed. 1989]. Noncombustible but accelerates the burning of combustible material. If the combustible material is finely divided, the mixture may be explosive. Mixtures with combustible material can sometimes be ignited by friction or contact with moisture. The hydrated material (of indefinite composition) explodes at 212 °C. Mixtures with aluminum or zinc powder burn brilliantly [Mellor 1940. v. 4, 530].

... WHEN MIXED WITH ALUMINUM POWDER OR ZINC POWDER, IT BURNS WITH DAZZLING LIGHT.

Incompatible with oxidizing and reducing agents. ...

... Will react with water or steam to produce heat. Vigorous reaction with reducing materials.

Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unbalanced levels of copper and zinc binding to Cu,Zn-superoxide dismutase has been linked to amyotrophic lateral sclerosis (ALS). Stomach acid dissolves metallic zinc to give corrosive zinc chloride, which can cause damage to the stomach lining. Metal fume fever is thought to be an immune response to inhaled zinc. (L48, L49, A49)

No indication of carcinogenicity to humans (not listed by IARC).

Chronic exposure to zinc causes anemia, atazia, lethargy, and decreases the level of good cholesterol in the body. It is also believed to cause pancreatic and reproductive damage. (L49)

Inhalation (L49) ; oral (L49) ; dermal (L49)

Ingestion of large doses of zinc causes stomach cramps, nausea, and vomiting. Acute inhalation of large amounts of zinc causes metal fume fever, which is characterized by chills, fever, headache, weakness, dryness of the nose and throat, chest pain, and coughing. Dermal contact with zinc results in skin irritation. (L49)

Zinc poisoning is treated symptomatically, often by administering fluids such as water or milk, or with gastric lavage. (L49)

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

/GUIDE 143: OXIDIZERS (Unstable)/ Fire or Explosion: May explode from friction, heat or contamination. These substances will accelerate burning when involved in a fire. May ignite combustibles (wood, paper, oil, clothing, etc.). Some will react explosively with hydrocarbons (fuels). Containers may explode when heated. Runoff may create fire or explosion hazard.

/GUIDE 143: OXIDIZERS (Unstable)/ Health: TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Fire may produce irritating and/or toxic gases. Toxic fumes or dust may accumulate in confined areas (basement, tanks, hopper/tank cars, etc.). Runoff from fire control or dilution water may cause pollution.

/GUIDE 143: OXIDIZERS (Unstable)/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering.

/GUIDE 143: OXIDIZERS (Unstable)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.

For more DOT Emergency Guidelines (Complete) data for ZINC PEROXIDE (8 total), please visit the HSDB record page.

UN 1516; ZINC PEROXIDE

IMO 5.1; Zinc peroxide

49 187 58; Zinc peroxide

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Oxidizer