Zirconium nitrate

H272 (100%): May intensify fire; oxidizer [Danger Oxidizing liquids; Oxidizing solids]

H314 (27.7%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

H318 (71.6%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

P210, P220, P260, P264, P264+P265, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P363, P370+P378, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 148 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P210, P220, P260, P264, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P370+P378, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 2 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

INHALATION: Move to fresh air.

INGESTION: Give large amount of water.

EYES or SKIN: Flush with water. (USCG, 1999)

General First Aid:

· Call 911 or emergency medical service.

· Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.

· Move victim to fresh air if it can be done safely.

· Administer oxygen if breathing is difficult.

· If victim is not breathing:

-- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.

-- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).

-- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.

· Remove and isolate contaminated clothing and shoes.

· For minor skin contact, avoid spreading material on unaffected skin.

· In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.

· For severe burns, immediate medical attention is required.

· Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed.

· Keep victim calm and warm.

· Keep victim under observation.

· For further assistance, contact your local Poison Control Center.

· Note: Basic Life Support (BLS) and Advanced Life Support (ALS) should be done by trained professionals.

Specific First Aid:

· Contaminated clothing may be a fire risk when dry.

In Canada, an Emergency Response Assistance Plan (ERAP) may be required for this product. Please consult the shipping paper and/or the "ERAP" section.

Excerpt from ERG Guide 140 [Oxidizers]:

SMALL FIRE: Use water. Do not use dry chemicals or foams. CO2 or Halon® may provide limited control.

LARGE FIRE: Flood fire area with water from a distance. Do not move cargo or vehicle if cargo has been exposed to heat. If it can be done safely, move undamaged containers away from the area around the fire.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: For ammonium nitrate products: Do not fight cargo fire. Withdraw, evacuate and isolate area for at least 1600 meters (1 mile). Treat as an explosive (ERG Guide 112). Do not enter area for 24 hours or until expert advice has been provided. Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Cool containers with flooding quantities of water until well after fire is out. ALWAYS stay away from tanks in direct contact with flames. For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn. (ERG, 2024)

If material on fire or involved in fire: Flood with water, cool all affected containers with flooding quantities of water, and apply water from as far a distance as possible.

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Keep unauthorized personnel away.

· Stay upwind, uphill and/or upstream.

· Ventilate closed spaces before entering, but only if properly trained and equipped.

· Keep combustibles (wood, paper, oil, etc.) away from spilled material.

· Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.

· Stop leak if you can do it without risk.

· Do not get water inside containers.

Small Dry Spill

· With clean shovel, place material into clean, dry container and cover loosely; move containers from spill area.

Small Liquid Spill

· Use a non-combustible material like vermiculite or sand to soak up the product and place into a container for later disposal.

Large Spill

· Dike far ahead of liquid spill for later disposal.

Excerpt from ERG Guide 140 [Oxidizers]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

LARGE SPILL: Consider initial downwind evacuation for at least 100 meters (330 feet).

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. If ammonium nitrate products are in a tank, rail car or truck and involved in a fire, ISOLATE for 1600 meters (1 mile) in all directions; also, initiate evacuation including emergency responders for 1600 meters (1 mile) in all directions. (ERG, 2024)

Immediate precautionary measure

· Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

· Consider initial downwind evacuation for at least 100 meters (330 feet).

· If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

· If ammonium nitrate products are in a tank, rail car or truck and involved in a fire, ISOLATE for 1600 meters (1 mile) in all directions; also, initiate evacuation including emergency responders for 1600 meters (1 mile) in all directions.

Environmental considerations: Land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. ... Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./

Environmental considerations: Water spill: Neutralize with agricultural lime (CaO), crushed limestone (CaCO3), or sodium bicarbonate (NaHCO3). ... Adjust pH to neutral (pH=7).

1. Ventilate area of spill. 2. Collect spilled material in the most convenient and safe manner and deposit in sealed containers for reclamation... . /Zirconium compound (as Zr)/

SRP: Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in air, soil or water; effects on animal, aquatic and plant life; and conformance with environmental and public health regulations. If it is possible or reasonable use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination.

If material not involved in fire: Keep sparks, flames, and other sources of ignition away and keep material out of water sources and sewers.

Personnel protection: Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water.

SRP: The scientific literature for the use of contact lenses by industrial workers is inconsistent. The benefits or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

Excerpt from ERG Guide 140 [Oxidizers]:

Keep combustibles (wood, paper, oil, etc.) away from spilled material. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Do not get water inside containers.

SMALL DRY SPILL: With clean shovel, place material into clean, dry container and cover loosely; move containers from spill area.

SMALL LIQUID SPILL: Use a non-combustible material like vermiculite or sand to soak up the product and place into a container for later disposal.

LARGE SPILL: Dike far ahead of liquid spill for later disposal. (ERG, 2024)

Keep tightly closed. /Zirconium nitrate pentahydrate/

· Wear positive pressure self-contained breathing apparatus (SCBA).

· Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE.

· Structural firefighters' protective clothing provides thermal protection but only limited chemical protection.

0.10 [mg/m3]

1.1 [mg/m3]

6.8 [mg/m3]

5.0 [mg/m3], as Zr (compounds)

25 mg Zr/m3 (NIOSH, 2024)

25.0 [mg/m3], as Zr

25 mg/cu m /Zirconium compounds (as Zr)/

5.0 [mg/m3], as Zr

10.0 [mg/m3], as Zr

8 hr Time Weighted Avg (TWA): 5 mg/cu m; 15 min Short Term Exposure Limit (STEL): 10 mg/cu m. /Zirconium and compounds, as Zr/

A4; Not classifiable as a human carcinogen. /Zirconium and compounds, as Zr/

Small Fire

· Use water. Do not use dry chemicals or foams. CO2 or Halon® may provide limited control.

Large Fire

· Flood fire area with water from a distance.

· Do not move cargo or vehicle if cargo has been exposed to heat.

· If it can be done safely, move undamaged containers away from the area around the fire.

Fire Involving Tanks, Rail Tank Cars or Highway Tanks

· For ammonium nitrate products: Do not fight cargo fire. Withdraw, evacuate and isolate area for at least 1600 meters (1 mile). Treat as an explosive (GUIDE 112). Do not enter area for 24 hours or until expert advice has been provided.

· Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.

· Cool containers with flooding quantities of water until well after fire is out.

· ALWAYS stay away from tanks in direct contact with flames.

· For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn.

West Germany: 5 mg/cu m (1974) /Zirconium, as Zr/

Dust mask; goggles or face shield; protective gloves (USCG, 1999)

/NIOSH-certified respirator/; goggles or face shield; protective gloves

Personnel protection: ... Wear appropriate chemical protective gloves, boots, and goggles. ... Wear positive pressure self-contained breathing apparatus.

Employees should be provided with and required to use impervious clothing, gloves, face shields (eight-in minimum), and other appropriate protective clothing necessary to prevent repeated or prolonged skin contact with zirconium oxide, zirconium oxychloride, zirconyl acetate, or liquids containing these compounds, and to prevent skin contact with zirconium tetrachloride or liquids containing zirconium tetrachloride, where skin contact may occur. /Zirconium compounds/

Respirator Recommendations: Up to 25 mg/cu m: /Zirconium compounds (as Zr)/ [Table#2789]

For more Personal Protective Equipment (PPE) (Complete) data for ZIRCONIUM NITRATE (7 total), please visit the HSDB record page.

Zirconium nitrate is a white crystalline solid. It is soluble in water. It is noncombustible, but it will accelerate the burning of combustible materials. If large quantities are involved in a fire or the combustible material is finely divided, an explosion may result. Prolonged exposure to fire or heat may result in an explosion. Toxic oxides of nitrogen are produced in fires involving this material. It is used as a preservative.

Colorless to white crystals that absorb moisture from the air; [HSDB]

White, hygroscopic crystals

Odorless

Decomposes at 100 °C

Very soluble in water

Soluble in alcohol

greater than 1 at 68 °F (USCG, 1999)

When heated to decomposition it emits toxic fumes of /nitrogen oxides/.

Index of refraction: 1.60, 1.61; deliquescent /Zirconium nitrate pentahydrate/

White very hygroscopic crystals or pieces, or scales; very soluble in water; soluble in alcohol; the aqueous solution is acid to litmus /Zirconium nitrate pentahydrate/

Molecular weight: 429.320; white hygroscopic crystals; decomposes at 100 °C; very soluble in water; soluble in ethanol /Zirconium nitrate pentahydrate/

Metals -> Metals, Inorganic Compounds

Water soluble.

Nitrate and Nitrite Compounds, Inorganic

Strong Oxidizing Agent

Mixtures of metal/nonmetal nitrates, such as ZIRCONIUM NITRATE, with alkyl esters may explode owing to the formation of alkyl nitrates; mixtures of a nitrate with phosphorus, tin (II) chloride, or other reducing agents may react explosively [Bretherick 1979. p. 108-109]. Dissolves in water to give an acid solution.

Strong oxidizing agent

IDENTIFICATION AND USE: Zirconium nitrate is a white hygroscopic crystal. It is used as a reagent and preservative. Also, it is used in pre-coatings applied on glass surfaces before the application of phosphor photo binder in the production of cathode-ray tubes. Zirconium nitrate has been identified as being used in hydraulic fracturing as a cross linker. HUMAN EXPOSURE AND TOXICITY: No human studies were found for this chemical. ANIMAL STUDIES: Zirconium nitrate has relatively low acute toxicity LD50 (rat oral 2290 mg/kg). Tested in vivo, zirconium nitrate was the most effective of 6 zirconium compounds in decreasing retention of (144) Cerium by liver and femur of rats. None affected strontium retention by tibia or femur. In vitro zirconium nitrate produced a slight inhibition of amylase activity at 0.53 mM concentration, a 20% inhibition of yeast invertase at 0.7 mM, and a 50% inhibition of serum alkaline phosphatase at 0.9 mM, but no inhibition of trypsin at 1 mM concentration. The rather low inhibitory effects produced on these enzymes at the zirconium concentrations used indicate no specific effect of zirconium on these particular enzymes.

Methemoglobinemia - The presence of increased methemoglobin in the blood; the compound is classified as secondary toxic effect

LCLo (rat) = 500 mg/m3/30 min

LD50 Rat oral 2290 mg/kg

Tested in vivo, zirconium nitrate was the most effective of 6 zirconium compounds in decreasing retention of (144)cerium by liver and femur of rats. None affected strontium retention by tibia or femur.

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Poisons A and B/

Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poisons A and B/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Consider administering a beta agonist such as albuterol for severe bronchospasm ... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W TKO /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) or lorazepam (Ativan) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poisons A and B/

/ALTERNATIVE and IN VITRO TESTS/ ... Produced a slight (10.5%) inhibition of amylase activity at 0.53 mM concentration in vitro, a 20% inhibition of yeast invertase at 0.7 mM, and a 50% inhibition of serum alkaline phosphatase at 0.9 mM, but no inhibition of trypsin at 1 mM concentration. The rather low inhibitory effects produced on these enzymes at the zirconium concentrations used indicate no specific effect of zirconium on these particular enzymes.

NIOSH (NOES Survey 1981-1983) has statistically estimated that 268 workers (none of these were female) were potentially exposed to zirconium nitrate in the US(1). Occupational exposure to zirconium nitrate may occur through inhalation of dust and dermal contact with this compound at workplaces where zirconium nitrate is produced or used(SRC).

NIOSH (NOES Survey 1981-1983) has statistically estimated that 268 workers (none of these were female) were potentially exposed to zirconium nitrate in the US(1). Occupational exposure to zirconium nitrate may occur through inhalation of dust and dermal contact with this compound at workplaces where zirconium nitrate is produced or used(SRC).

SRP: Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in air, soil or water; effects on animal, aquatic and plant life; and conformance with environmental and public health regulations. If it is possible or reasonable use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination.

/GUIDE 140 OXIDIZERS/ Fire or Explosion: These substances will accelerate burning when involved in a fire. Some may decompose explosively when heated or involved in a fire. May explode from heat or contamination. Some will react explosively with hydrocarbons (fuels). May ignite combustibles (wood, paper, oil, clothing, etc.). Containers may explode when heated. Runoff may create fire or explosion hazard.

/GUIDE 140 OXIDIZERS/ Health: Inhalation, ingestion or contact (skin, eyes) with vapors or substance may cause severe injury, burns or death. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may cause pollution.

/GUIDE 140 OXIDIZERS/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering.

/GUIDE 140 OXIDIZERS/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing will only provide limited protection.

For more DOT Emergency Guidelines (Complete) data for ZIRCONIUM NITRATE (8 total), please visit the HSDB record page.

UN 2728; Zirconium nitrate

IMO 5.1; Zirconium nitrate

49 187 91; Zirconium nitrate

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

For more Shipment Methods and Regulations (Complete) data for ZIRCONIUM NITRATE (6 total), please visit the HSDB record page.

Oxidizer