English Safety Data Sheet Database 中文版 MSDS

tetrahydropyran

CAS No. 142-68-7 | PubChem CID 8894
Section 1. Identification
Chemical Nametetrahydropyran CAS No.142-68-7
Synonymspentamethyleneoxide Chinese Name四氢吡喃
Molecular FormulaC5H10O Molecular Weight86.1323
UN No.3271 Data SourcePubChem (NIH/NLM)
GHS Hazard Classification
Signal Word DANGER
Pictograms GHS02 · Flammable GHS07 · Irritant
Hazard Statements H225H315H319H335
Precautionary Statements P210P233P240P241P242P243P261P264P264+P265P271P280P302+P352P303+P361+P353P304+P340P305+P351+P338P319P321P332+P317P337+P317P362+P364P370+P378P403+P233P403+P235P405P501

Section 2. Hazards Identification

H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]

H315 (82.4%): Causes skin irritation [Warning Skin corrosion/irritation]

H319 (82.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H335 (80.4%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 51 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

H225: Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, and P501 (click each P-code to see the statement)

Section 5. Fire-Fighting Measures

ALCOHOL FOAM.

Section 9. Physical and Chemical Properties

Colorless liquid with a pungent sweet odor like ether; [HSDB]

COLORLESS, MOBILE LIQUID

PUNGENT, SWEETISH ODOR

ETHER-LIKE

-49.2 °C

-4.0 °F (-20 °C) CC

MISCIBLE WITH ALC, ETHER, MANY OTHER ORG SOLVENTS

SOL IN BENZENE

water solubility = 80,200 mg/l @ 25 °C

0.8814 @ 20 °C/4 °C

4.0 (AIR= 1)

71.5 [mmHg]

vapor pressure = 71.5 mm Hg @ 25 °C

log Kow = 0.95

Henry's Law constant = 1.25X10-4 atm-cu m/mol @ 25 °C

FORMS PEROXIDES ON EXPOSURE TO AIR

INDEX OF REFRACTION: 1.4211 @ 20 °C/D

AZEOTROPE WITH WATER, BP 71 °C, CONTAINS 8.5% WATER; DIPOLE MOMENT: 1.87

hydroxyl radical rate constant = 1.38X10-11 cu m/molc-sec @ 25 °C

Coriolis coupling

Schoenflies notation

Atomic environment

Boiling point

Centrifugal distortion

Chemical bond

Chemical shift

Dielectric constant

Electric dipole moment

Equilibrium structure

Excess enthalpy

Fusion temperature

Heat of solution

Heat of sublimation

Internuclear distance

Lineshape

Melting temperature

Mixing enthalpy

Molecular structure

Nuclear magnetic resonance

Nuclear quadrupole coupling

Section 10. Stability and Reactivity

Tetrahydropyran

D: Other compounds that may form peroxides

Section 11. Toxicological Information

Neurotoxin - Acute solvent syndrome

LDLO RATS ORAL 3000 MG/KG

Source: PubChem CID 8894 (NIH/NLM, public domain). Retrieved from PubChem, a public-domain chemistry database maintained by the U.S. National Library of Medicine. Last updated: 2026-08-02 09:57:39.
Disclaimer: This information is compiled for reference only and does not replace the manufacturer's official Safety Data Sheet. Always consult the supplier's SDS before handling any chemical.