English Safety Data Sheet Database 中文版 MSDS

Trimethyl orthoacetate

CAS No. 1445-45-0 | PubChem CID 15050
Section 1. Identification
Chemical NameTrimethyl orthoacetate CAS No.1445-45-0
Synonymstrimethyl ortho-acetate; 1,1,1-trimethoxyethane Chinese Name1,1,1-三甲氧基乙烷
Molecular FormulaC5H12O3 Molecular Weight120.147
UN No.3272 Data SourcePubChem (NIH/NLM)
GHS Hazard Classification
Signal Word DANGER
Pictograms GHS02 · Flammable GHS07 · Irritant
Hazard Statements H225H317H319
Precautionary Statements P210P233P240P241P242P243P261P264+P265P272P280P302+P352P303+P361+P353P305+P351+P338P321P333+P317P337+P317P362+P364P370+P378P403+P235P501

Section 2. Hazards Identification

This chemical does not meet GHS hazard criteria for 2.5% (5 of 201) of reports.

H225 (97.5%): Highly Flammable liquid and vapor [Danger Flammable liquids]

H317 (76.1%): May cause an allergic skin reaction [Warning Sensitization, Skin]

H319 (75.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P210, P233, P240, P241, P242, P243, P261, P264+P265, P272, P280, P302+P352, P303+P361+P353, P305+P351+P338, P321, P333+P317, P337+P317, P362+P364, P370+P378, P403+P235, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 201 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria per 5 of 201 reports by companies.

There are 9 notifications provided by 196 of 201 reports by companies with hazard statement code(s).

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Section 9. Physical and Chemical Properties

CBI; Liquid

Schoenflies notation

Chemical bond

Chemical shift

Internuclear distance

Lineshape

Molecular structure

Optical coefficient

Point group

Refractive index

Source: PubChem CID 15050 (NIH/NLM, public domain). Retrieved from PubChem, a public-domain chemistry database maintained by the U.S. National Library of Medicine. Last updated: 2026-08-02 09:55:10.
Disclaimer: This information is compiled for reference only and does not replace the manufacturer's official Safety Data Sheet. Always consult the supplier's SDS before handling any chemical.