1-Ethoxy-2-propanol

H226: Flammable liquid and vapor [Warning Flammable liquids]

H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]

P210, P233, P240, P241, P242, P243, P261, P271, P280, P303+P361+P353, P304+P340, P319, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

This chemical does not meet GHS hazard criteria for 1.8% (12 of 670) of reports.

H226 (98.2%): Flammable liquid and vapor [Warning Flammable liquids]

H319 (23%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H336 (98.2%): May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]

P210, P233, P240, P241, P242, P243, P261, P264+P265, P271, P280, P303+P361+P353, P304+P340, P305+P351+P338, P319, P337+P317, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 670 reports by companies from 26 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria per 12 of 670 reports by companies.

There are 25 notifications provided by 658 of 670 reports by companies with hazard statement code(s).

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

H320: Causes eye irritation [Warning Serious eye damage/eye irritation]

H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Fresh air, rest.

Remove contaminated clothes. Rinse skin with plenty of water or shower.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth.

Call for medical aid.

INHALATION: Remove to fresh air.

SKIN OR EYES: Immediately flush with plenty of water. (USCG, 1999)

Fire Extinguishing Agents: Alcohol foam, water spray, dry chemical or carbon dioxide. (USCG, 1999)

Use water spray, powder, foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.

Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

LARGE SPILL: Consider initial downwind evacuation for at least 300 meters (1000 feet).

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Remove all ignition sources. Ventilation. Personal protection: face shield. Collect leaking and spilled liquid in sealable containers as far as possible.

Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean, non-sparking tools to collect absorbed material.

LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2024)

Fireproof. Separated from strong oxidants.

20.0 [ppm], Sum of the concentrations of CAS 1569-02-4 and 54839-24-6 in air[German Research Foundation (DFG)]

50.0 [ppm]

200.0 [ppm]

50 ppm as TWA; 200 ppm as STEL; (skin).

No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.

The substance is mildly irritating to the eyes.

Approved respirator; rubber gloves; goggles; clothing to prevent body contact with liquid. (USCG, 1999)

NO open flames, NO sparks and NO smoking. Above 40 °C use a closed system and ventilation.

Use ventilation, local exhaust or breathing protection.

Protective gloves.

Wear safety spectacles.

Do not eat, drink, or smoke during work.

Propylene glycol ethyl ether is a colorless liquid. (USCG, 1999)

Clear, hygroscopic liquid with a sweet, mild, ether-like odor; [CHEMINFO]

COLOURLESS LIQUID WITH MILD ODOUR.

40 °C c.c.

Solubility in water, g/100ml at 25 °C: 36.6

Relative density (water = 1): 0.896

Relative vapor density (air = 1): 3.6

9.8 [mmHg]

Vapor pressure, kPa at 25 °C: 1

2.32 mm²/s at 20 °C

Optical coefficient

Refractive index

Viscosity

Solvents -> Glycol Ethers (P Series)

Oxidizes readily in air to form unstable peroxides that may explode spontaneously [Bretherick 1979 p.151-154, 164].

Alcohols and Polyols

Peroxidizable Compound

PROPYLENE GLYCOL ETHYL ETHER may react violently with strong oxidizing agents. May generate flammable and/or toxic gases with alkali metals, nitrides, and other strong reducing agents. May initiate the polymerization of isocyanates and epoxides.

Redness.

Neurotoxin - Acute solvent syndrome

Lacrimator (Lachrymator) - A substance that irritates the eyes and induces the flow of tears.

beta-Propylene Glycol Monoethyl Ether

PDF Document

HEAST Archive

LC50 (rat) > 10,000 ppm/4h

Flammable Liquid

R: 10-67; S: (2)-24

UN Hazard Class: 3; UN Pack Group: III