Sodium hexafluorosilicate

This chemical does not meet GHS hazard criteria for 2.7% (11 of 405) of reports.

H301 (97.3%): Toxic if swallowed [Danger Acute toxicity, oral]

H311 (83.5%): Toxic in contact with skin [Danger Acute toxicity, dermal]

H331 (96%): Toxic if inhaled [Danger Acute toxicity, inhalation]

P261, P262, P264, P270, P271, P280, P301+P316, P302+P352, P304+P340, P316, P321, P330, P361+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 405 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria per 11 of 405 reports by companies.

There are 9 notifications provided by 394 of 405 reports by companies with hazard statement code(s).

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]

H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P273, and P501 (click each P-code to see the statement)

Fresh air, rest. Refer for medical attention.

Remove contaminated clothes. Rinse skin with plenty of water or shower.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention.

In case of fire in the surroundings, use appropriate extinguishing media.

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Separated from acids and food and feedstuffs.

Biological Exposure Indices (BEI) [ACGIH] - Fluorides in urine = 2 mg/L prior to shift or 3 mg/L at end of shift; (Repeated measurements recommended.)

1.0 [mg/m3], inhalable fraction, as F[German Research Foundation (DFG)]

0.60 [mg/m3]

13 [mg/m3]

80 [mg/m3]

2.5 [mg/m3], as F

250.0 [mg/m3], as F

8 hr Time Weighted Avg (TWA): 2.5 mg/cu m. /Fluorides, as F/

Excursion Limit Recommendation: Excursions in worker exposure levels may exceed 3 times the TLV-TWA for no more than a total of 30 minutes during a work day, and under no circumstances should they exceed 5 times the TLV-TWA, provided that the TLV-TWA is not exceeded. /Fluorides, as F/

A4; Not classifiable as a human carcinogen. /Fluorides, as F/

Biological Exposure Index (BEI): Determinant: fluorides in urine; Sampling Time: prior to shift; BEI: 3 mg/g creatinine. Determinant: fluorides in urine; Sampling Time: end of shift; BEI: 10 mg/g creatinine. The determinant may be present in biological specimens collected from subjects who have not been occupationally exposed, at a concentration which could affect interpretation of the result. Such background concentrations are incorporated in the BEI value. The determinant is nonspecific, since it is also observed after exposure to other chemicals. /Fluorides/

A harmful concentration of airborne particles can be reached quickly when dispersed.

The substance may cause effects on the blood and calcium metabolism. This may result in cardiac disorders. Medical observation is indicated.

The substance may have effects on the bones and teeth. This may result in fluorosis.

PREVENT DISPERSION OF DUST!

Avoid inhalation of dust. Use local exhaust or breathing protection.

Protective gloves. Protective clothing.

Wear safety goggles or eye protection in combination with breathing protection if powder.

Do not eat, drink, or smoke during work. Wash hands before eating.

Dry Powder; Large Crystals; CBI

White solid; [Merck Index] White powder; [MSDSonline]

COLOURLESS-TO-WHITE GRANULAR POWDER.

WHITE GRANULAR POWDER

White, hexagonal crystals.

White, crystalline powder.

White, free-flowing powder.

Odorless

Tasteless.

Melts at red heat with decomposition.

SOL IN 150 PARTS COLD, 40 PARTS BOILING WATER; INSOL IN ALCOHOL

Insoluble in ethanol.

In water, 0.64 g/100 g at 20 °C, 0.76 g/100 g at 25 °C, 1.27 g/100 g at 50 °C, 2.45 g/100 g at 100 °C.

Solubility in water, g/100ml at 20 °C: 0.76 (poor)

2.7 g/cu cm.

Relative density (water = 1): 2.7

2.7 @25 °C

When heated to decomposition it emits toxic fumes of /hydrogen fluoride/ and Na2O.

SOLN IN COLD WATER IS NEUTRAL

INDEX OF REFRACTION: 1.312, 1.309

Solutions of fluosilicates are sensitive to hydrolysis in alkaline medium. In the presence of acid, fluosilicate solutions release silicon tetrafluoride. The thermal decomposition of fluosilicates takes place with release of gaseous silicon tetrfluoride and formation of the solid fluoride. /Fluosilicates/

Metals -> Metals, Inorganic Compounds

Antiplaque; Oral care

Insecticides

Active substance -> EU Pesticides database: Not approved

A4; Not classifiable as a human carcinogen. /Fluorides, as F/

The substance can be absorbed into the body by ingestion.

Burning sensation. Cough. Sore throat. See Ingestion.

Redness. Pain.

Redness. Pain. Blurred vision.

Abdominal cramps. Burning sensation. Nausea. Vomiting. Sore throat. Weakness. Convulsions. Shock or collapse.

LCLo (humans) = 33 mg/m3/6h

LD50 Rat oral 125 mg/kg

TREATMENT: A. INGESTION OF SOL FLUORIDE SALTS... 1. START IV INFUSION OF GLUCOSE IN ISOTONIC SALINE. 2. INJECT IV 10 ML OF 10% CALCIUM GLUCONATE SOLN. REPEAT IN ABOUT 1 HR &/OR WHENEVER TETANY APPEARS. 3. GENTLE GASTRIC LAVAGE WITH LIME WATER OR 1% SOLN OF CALCIUM CHLORIDE... /FLUORIDE/

TREATMENT: 3. ... ALUMINUM HYDROXIDE GELS SHOULD BE EXCEPTIONALLY EFFECTIVE FOR BINDING FLUORIDE. 4. INJECT IM 10 ML OF 10% CALCIUM GLUCONATE @ 4-6 HOUR INTERVALS UNTIL RECOVERY IS COMPLETE... /FLUORIDE/

TREATMENT: 5. TREAT SHOCK VIGOROUSLY BY ADMIN OF SALINE, PLASMA, OR WHOLE BLOOD... NOREPINEPHRINE IS PROBABLY USEFUL. GIVE OXYGEN AS NEEDED. KEEP PT WARM. 6. CORRECT DEHYDRATION & ATTEMPT TO MAINTAIN A MILD DIURESIS, BUT DISCONTINUE FLUIDS & ELECTROLYTES...IF ANURIA DEVELOPS... /FLUORIDE/

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 m1 of water for dilution if the patent can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Fluorine and related compounds/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in respiratory arrest. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W TKO /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's to support vital signs if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors for hypotension with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Fluorine and related compounds/

SYMPTOMATOLOGY: A. INGESTION OF SOL FLUORIDE SALTS... 1. SALTY OR SOAPY TASTE, SALIVATION, NAUSEA, BURNING OR CRAMPY ABDOMINAL PAIN, VOMITING, DIARRHEA (MAY BE BLOODY). DEHYDRATION & THIRST. 2. MUSCLE WEAKNESS, TREMORS, & RARELY TRANSIENT EPILEPTIFORM CONVULSIONS...CENTRAL NERVOUS DEPRESSION. /FLUORIDE/

SYMPTOMATOLOGY /INGESTION/: 3. SHOCK CHARACTERIZED BY PALLOR, WEAK & THREADY PULSE...SHALLOW UNLABORED RESP, WEAK HEART SOUNDS, WET COLD SKIN, CYANOSIS, DILATED PUPILS, FOLLOWED...BY DEATH IN 2-4 HR. 4. ...PARALYSIS OF MUSCLE OF DEGLUTITION, CARPOPEDAL SPASM, & SPASM OF EXTREMITIES. /FLUORIDE/

SYMPTOMATOLOGY /INGESTION/: 5. OCCASIONALLY LOCALIZED OR GENERALIZED URTICARIA. /FLUORIDE/

A 2 1/2-year old girl ingested sodium silicofluoride, developed acute respiratory failure, a prolonged AT interval, ventricular tachycardia and fibrillation, hypokalemia, hypocalcemia (3 to 4 mg/100 ml), and aspiration pneumonia.

COMPD WITH HIGH WATER SOLUBILITY SUCH AS...SODIUM FLUOSILICATE PRODUCE SEVERE PLANT DAMAGE. ...HIGHLY TOXIC TO FOLIAGE.

.../RESEARCHERS/ EXPOSED GUINEA PIGS TO AIR BEARING SODIUM SILICOFLUORIDE AS DUST IN CONCN RANGING FROM 13-55 MG/CU M & FOUND DUST CAPABLE OF CAUSING PULMONARY IRRITATION. THEY CONCLUDED THAT LEAST CONCN THAT CAUSED DEATH WHEN INHALED FOR PERIOD OF 6 HR WAS 33 MG/CU M.

DAIRY HERD OF 600 ANIMALS BECAME POISONED AS A RESULT OF RAILCAR CONTAMINATION OF FEED; 95% OF HERD AFFECTED WITH SIGNS OF DECR NEUROMUSCULAR TRANSMISSION. TREATMENT WITH CALCIUM GLUCONATE IV WAS EFFECTIVE. ACUTE POISONING RESEMBLED CALCIUM DEPLETION.

AVOID INHALATION OF DUSTS

AVOID INHALATION OF DUSTS

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Health: TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Fire or Explosion: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate enclosed areas.

/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.

For more DOT Emergency Guidelines (Complete) data for SODIUM SILICOFLUORIDE (8 total), please visit the HSDB record page.

UN 2674 ; Sodium silicofluoride

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.

Do not transport with food and feedstuffs.

Symbol: T; R: 23/24/25; S: (1/2)-26-45; Note: A

UN Hazard Class: 6.1; UN Pack Group: III