dipentylamine

H226 (40.3%): Flammable liquid and vapor [Warning Flammable liquids]

H301+H311+H331 (58.2%): Toxic if swallowed, in contact with skin or if inhaled [Danger Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]

H301 (61.2%): Toxic if swallowed [Danger Acute toxicity, oral]

H302 (38.8%): Harmful if swallowed [Warning Acute toxicity, oral]

H311 (100%): Toxic in contact with skin [Danger Acute toxicity, dermal]

H314 (61.2%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

H315 (38.8%): Causes skin irritation [Warning Skin corrosion/irritation]

H319 (38.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H331 (59.7%): Toxic if inhaled [Danger Acute toxicity, inhalation]

H335 (38.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

H400 (59.7%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

P210, P233, P240, P241, P242, P243, P260, P261, P262, P264, P264+P265, P270, P271, P273, P280, P301+P316, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P363, P370+P378, P391, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 67 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.

Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Rest. Refer for medical attention .

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Generally, the induction of vomiting is NOT recommended outside of a physician's care due to the risk of aspirating the chemical into the victim's lungs. However, if the victim is conscious and not convulsing and if medical help is not readily available, consider the risk of inducing vomiting because of the high toxicity of the chemical ingested. Ipecac syrup or salt water may be used in such an emergency. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

General First Aid:

· Call 911 or emergency medical service.

· Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.

· Move victim to fresh air if it can be done safely.

· Administer oxygen if breathing is difficult.

· If victim is not breathing:

-- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.

-- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).

-- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.

· Remove and isolate contaminated clothing and shoes.

· For minor skin contact, avoid spreading material on unaffected skin.

· In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.

· For severe burns, immediate medical attention is required.

· Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed.

· Keep victim calm and warm.

· Keep victim under observation.

· For further assistance, contact your local Poison Control Center.

· Note: Basic Life Support (BLS) and Advanced Life Support (ALS) should be done by trained professionals.

Specific First Aid:

· Wash skin with soap and water.

· In case of burns, immediately cool affected skin for as long as possible with cold water. Do not remove clothing if adhering to skin.

In Canada, an Emergency Response Assistance Plan (ERAP) may be required for this product. Please consult the shipping paper and/or the "ERAP" section.

Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]:

CAUTION: The majority of these products have a very low flash point. Use of water spray when fighting fire may be inefficient. CAUTION: Methanol (UN1230) will burn with an invisible flame. Use an alternate method of detection (thermal camera, broom handle, etc.).

SMALL FIRE: Dry chemical, CO2, water spray or alcohol-resistant foam.

LARGE FIRE: Water spray, fog or alcohol-resistant foam. If it can be done safely, move undamaged containers away from the area around the fire. Dike runoff from fire control for later disposal. Avoid aiming straight or solid streams directly onto the product.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn. (ERG, 2024)

Use water spray, powder, alcohol-resistant foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.

USE DRY CHEMICAL, CARBON DIOXIDE, FOAM, OR WATER SPRAY. WATER MAY BE INEFFECTIVE. USE WATER SPRAY TO KEEP FIRE-EXPOSED CONTAINERS COOL. APPROACH FIRE FROM UPWIND TO AVOID HAZARDOUS VAPORS & TOXIC DECOMPOSITION PRODUCTS.

If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible.

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Keep unauthorized personnel away.

· Stay upwind, uphill and/or upstream.

· Ventilate closed spaces before entering, but only if properly trained and equipped.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

· All equipment used when handling the product must be grounded.

· Do not touch or walk through spilled material.

· Stop leak if you can do it without risk.

· Prevent entry into waterways, sewers, basements or confined areas.

· A vapor-suppressing foam may be used to reduce vapors.

Small Spill

· Absorb with earth, sand or other non-combustible material and transfer to containers for later disposal.

· Use clean, non-sparking tools to collect absorbed material.

Large Spill

· Dike far ahead of liquid spill for later disposal.

· Water spray may reduce vapor, but may not prevent ignition in closed spaces.

Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Immediate precautionary measure

· Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

· For highlighted materials: see Table 1 - Initial Isolation and Protective Action Distances.

· For non-highlighted materials: increase the immediate precautionary measure distance, in the downwind direction, as necessary.

· If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Personal protection: chemical protection suit including self-contained breathing apparatus. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to knock down vapors.

Personnel protection: Avoid breathing vapors. Keep upwind. Wear positive pressure self-contained breathing apparatus. Avoid bodily contact with the material. Wear appropriate chemical protective clothing. Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water.

Evacuation: If material leaking (not on fire) consider evacuation from downwind area based on amount of material spilled, location and weather conditions.

Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors.

SMALL SPILL: Absorb with earth, sand or other non-combustible material and transfer to containers for later disposal. Use clean, non-sparking tools to collect absorbed material.

LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2024)

Fireproof. Separated from food and feedstuffs. See Chemical Dangers. Cool. Dry. Well closed. Keep in a well-ventilated room.

Store in a cool, dry, well ventilated location. Separate from acids and oxidizing materials.

· Wear positive pressure self-contained breathing apparatus (SCBA).

· Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE.

· Structural firefighters' protective clothing provides thermal protection but only limited chemical protection.

0.041 [ppm]

0.45 [ppm]

2.7 [ppm]

CAUTION: The majority of these products have a very low flash point. Use of water spray when fighting fire may be inefficient.

CAUTION: Methanol (UN1230) will burn with an invisible flame. Use an alternate method of detection (thermal camera, broom handle, etc.)

Small Fire

· Dry chemical, CO2, water spray or alcohol-resistant foam.

Large Fire

· Water spray, fog or alcohol-resistant foam.

· If it can be done safely, move undamaged containers away from the area around the fire.

· Dike runoff from fire control for later disposal.

· Avoid aiming straight or solid streams directly onto the product.

Fire Involving Tanks, Rail Tank Cars or Highway Tanks

· Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.

· Cool containers with flooding quantities of water until well after fire is out.

· Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.

· ALWAYS stay away from tanks in direct contact with flames.

· For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn.

No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.

The substance is corrosive to the skin and eyes. The substance is severely irritating to the respiratory tract. Inhalation of the vapour or mist may cause lung oedema. The substance may cause effects on the central nervous system.

Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]:

Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE. Structural firefighters' protective clothing provides thermal protection but only limited chemical protection. (ERG, 2024)

NO open flames, NO sparks and NO smoking. Above 51 °C use a closed system, ventilation and explosion-proof electrical equipment.

PREVENT GENERATION OF MISTS!

Use ventilation, local exhaust or breathing protection.

Protective gloves. Protective clothing.

Wear face shield.

Do not eat, drink, or smoke during work.

Di-n-amylamine appears as a clear colorless liquid with an ammonia-like odor. Very slightly soluble in water. Less dense less than water. Vapors heavier than air. Difficult to ignite. Moderately toxic. Contact with liquid may cause a chemical burn. Vapors may irritate respiratory tract. Used in the manufacture of rubber, resins, and dyes.

Colorless to light yellow liquid; [ICSC] Ammoniacal or fishy odor; [CHEMINFO] Clear colorless liquid; [MSDSonline]

COLOURLESS-TO-LIGHT-YELLOW LIQUID WITH PUNGENT ODOUR.

COLORLESS TO WATER-WHITE TO PALE-YELLOW LIQUID

CHARACTERISTIC AMINE ODOR

396 to 397 °F at 760 mmHg (NTP, 1992)

202.5 °C

202-203 °C

202.5 °C @760 [mm Hg]

-47 °F (NTP, 1992)

-7.85 °C

124 °F (NTP, 1992)

124 °F (51 °C) (CLOSED CUP)

51 °C c.c.

Slightly soluble (1-10 mg/ml) (NTP, 1992)

Sol in acetone; very sol in alcohol; miscible with ether; slightly sol in water

Solubility in water: none

0.7771 at 68 °F (NTP, 1992) - Less dense than water; will float

0.7771 @ 20 °C/4 °C

Relative density (water = 1): 0.8

0.777 @25 °C

5.4 (AIR= 1)

Relative vapor density (air = 1): 5.4

0.15 [mmHg]

0.153 mm HG @ 25 °C

Vapor pressure, Pa at 20 °C: 40

0.153 [mm Hg] @25 °C

When heated to decomp it emits toxic fumes of /nitrogen oxides/.

Index of refraction: 1.4272 @ 20 °C

pKa= 11.16 (conjugate acid)

Flash point = 124 °F

Liquid molar volume = 0.203 cu m/kmol

Boiling point

Heat of sublimation

Optical coefficient

Refractive index

Surface tension

Thermal expansion coefficient

Vapor pressure

Viscosity

Flammable. Sensitive to air and heat. Slightly soluble in water.

Amines, Phosphines, and Pyridines

DI-N-AMYLAMINE neutralizes acids to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides.

... Can react with oxidizing materials.

The substance can be absorbed into the body by inhalation of its aerosol or vapour, through the skin and by ingestion.

Burning sensation. Cough. Headache. Nausea. Shortness of breath. Sore throat. Symptoms may be delayed.

Redness. Serious skin burns.

Redness. Blurred vision. Severe deep burns.

Shock or collapse. Further see Inhalation.

Dermatotoxin - Skin burns.

Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.

LCLo (rat) = 63 ppm/4h

LD50 Rat oral 270 mg/kg

LD50 Rabbit skin 350 mg/kg

TREATMENT OF SECONDARY AMINES (SUCH AS DIPENTYLAMINE) WITH NITROUS ACID IN DIL AQUEOUS SOLN GAVE OPTIMUM YIELD OF NITROSAMINES BETWEEN PH 1 & 3, CORRESPONDING TO CONDITIONS IN HUMAN & ANIMAL STOMACH. SYNTHESIS OF NITROSAMINES IN STOMACH OF RATS WAS DEMONSTRATED WHEN DIET WAS SUPPLEMENTED WITH SODIUM NITRITE & SECONDARY AMINES OF LOW BASICITY. PRODUCTION OF MALIGNANT TUMORS THROUGH FORMATION OF NITROSAMINES IN STOMACH OCCURRED ONLY IF NITRITE WAS PRESENT IN STOMACH CONCOMITANTLY WITH SECONDARY AMINES WHICH READILY FORM CARCINOGENIC NITROSAMINES.

RATED 5 (ON SCALE OF 1 TO 10) WHEN TESTED EXTERNALLY ON EYES OF RABBITS ACCORDING TO DEGREE OF INJURY OBSERVED AFTER 24 HR, PAYING PARTICULAR ATTENTION TO CONDITION OF CORNEA. MOST SEVERE INJURIES HAVE BEEN RATED 10.

The oral LD50 of diamylamine in rats is reported to be 270 mg/kg body weight. ... When applied dermally to rabbit skin, severe skin irritation was observed at 500 mg. When applied undiluted to the rabbit eye, a severe burn resulted from a 0.05 ml dose. After 4 hr exposure at a concn of 63 ppm diamylamine, 4 of 6 rats were dead. When exposed to saturated vapors, rats were able to survive 14 d following a 30 min exposure.

The acute inhalation toxicity of diamylamine (2050-92-2) was evaluated in 6 groups of Sprague-Dawley rats (5/sex/group) exposed for 4 hours to diamylamine vapor in a environmental chamber at average metered concentrations of 43, 52, 60, 67, 75, and 82 ppm. All mortality occurred within 24 hours of exposure and an LC50 with 95% confidence limits calculated by the method of Litchfield and Wilcoxon was 66 (59-73) ppm. Among the decedents, tremors and clonic convulsions during exposure often heralded death; There were no other outward signs of pathology. During 14-week post-exposure observation, all but 4 females of the survivors gained weight. Examination of upper and lower respiratory tract, liver, heart, GI tract and kidneys from both study survivors and lethalities identified no gross pathology.

Dermal irritancy and corrosivity of di-amylamine (2050-92-2) was evaluated in 6 New Zealand White rabbits each administered three 0.5 mL dermal applications upon intact skin at 3 distinct sites. The semi-occlusive bindings covering the 3 applications were removed and the skin cleansed of any residual test article at 3-minute, 1-hour, and 2-hour intervals respectively. Signs of irritation or corrosion were assessed immediately and at 1 hour following removal of the patches according to the Dermal Grading System for Potential In-Depth Injury at the 3-minute sites and by the method of Draize at the 1- and 2-hour sites. Upon a 1-hour assessment after removal of the 2-hour application, humane euthanasia of all treated animals due to excessive dermal irritation terminated study. Nearly all test sites for all exposure periods exhibited slight to moderate blanching initially. The 3-minute exposure also produced slight necrosis at 1 site that was more severe and prevalent with increasing periods of exposure. Both 1-hour and 2-hour applications were also characterized by severe erythema and slight-moderate edema. One hour following removal of patches, grade 1-4 necrosis was noted on all sites of 3-minute or 1-hour exposures, while grade 1-3 eschar and severe edema was found on all 2-hour exposure sites. Superficial lightening and erythema extending beyond the test site were also noted in both 1- and 2-hour sites, while ulceration beyond the test site characterized 2-hour sites only 1 hour after patch removal. Researchers concluded that di-amylamine is corrosive to rabbit skin at 3-minute, 1-hour and 2-hour long exposures.

Environmental effects from the substance have not been investigated adequately.

Dipentylamine's production and use as a rubber accelerator, flotation reagent, dyestuffs and corrosion inhibitor, as a solvent of oils, resins, and some cellulose esters may result in its release to the environment through various waste streams. If released to air, a vapor pressure of 0.15 mm Hg at 25 °C indicates dipentylamine will exist solely as a vapor in the ambient atmosphere. Vapor-phase dipentylamine will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 4 hours. If released to soil, dipentylamine is expected to have low mobility based upon an estimated Koc of 1,800. The pKa of dipentylamine is 11.16, indicating that this compound will exist in the protonated form in the environment and cations generally adsorb more strongly than their neutral counterparts. Volatilization from moist soil surfaces is not expected to be an important fate process because the cation will not volatilize. Dipentylamine is not expected to volatilize from dry soil surfaces based upon its vapor pressure. If released into water, dipentylamine is expected to adsorb to suspended solids and sediment in the water column based upon the estimated Koc. Screening biodegradation studies on other aliphatic amines suggest that dipentylamine may biodegrade in the environment. Volatilization from water surfaces is not expected to be an important fate process since this compound is expected to exist in the protonated form in water surfaces at environmental pH. An estimated BCF of 156 suggests the potential for bioconcentration in aquatic organisms is high. Occupational exposure to dipentylamine may occur through inhalation and dermal contact with this compound at workplaces where dipentylamine is produced or used. (SRC)

Dipentylamine's production and use as a rubber accelerator, flotation reagent, dyestuffs and corrosion inhibitor, and as a solvent of oils, resins, and some cellulose esters(1) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 1,800(SRC) from an estimated log Kow of 3.76(2) and a regression derived equation(3) indicates that dipentylamine is expected to have low mobility in soil(SRC). A pKa value of 11.16(4) indicates that the protonated form of dipentylamine will be the dominant species in moist soil surfaces and cations generally adsorb strongly to soils. Volatilization of dipentylamine from moist soil surfaces is not expected to be an important fate process since the cation will not volatilize. Dipentylamine is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 0.15 mm Hg at 25 °C(5). Screening biodegradation studies on other aliphatic amines(6-11) suggest that dipentylamine may biodegrade in soil(SRC).

AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 1,800(SRC) from an estimated log Kow of 3.76(2) and a regression derived equation(3) indicates that dipentylamine is expected to adsorb to suspended solids and sediment in water(SRC). A pKa value of 11.16(4) indicates that the protonated form of dipentylamine will be the predominant species in water. Volatilization from water surfaces is not expected to be important fate process(SRC) since the protonated form will not volatilize. According to a classification scheme(5), an estimated BCF of 156(SRC), from its log Kow(2) and a regression-derived equation(6), suggests the potential for bioconcentration in aquatic organisms is high(SRC). Screening biodegradation studies on other aliphatic amines(7-12) suggest that dipentylamine may biodegrade in water(SRC).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), dipentylamine, which has a vapor pressure of 0.15 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase dipentylamine is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 4 hours(SRC), from its rate constant of 9X10-11 cu cm/molecule-sec at 25 °C(3). Dipentylamine is not expected to directly photolyze due to the lack of absorption in the environmental UV spectrum(SRC).

No data was found regarding the biodegradation of dipentylamine; however, screening studies on other aliphatic amines(1-6) suggest that dipentylamine may biodegrade in the environment(SRC).

The rate constant for the vapor-phase reaction of dipentylamine with photochemically-produced hydroxyl radicals has been estimated as 9X10-11 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 4 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). Dipentylamine will exist predominantly in the protonated form in the environment based on a pKa value of 11.16(2). Dipentylamine is not expected to directly photolyze due to the lack of absorption in the environmental UV spectrum(SRC).

An estimated BCF of 156 was calculated for dipentylamine(SRC), using an estimated log Kow of 3.76(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is high(SRC).

The Koc of dipentylamine was estimated as 1,800(SRC), using an estimated log Kow of 3.76(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that dipentylamine is expected to have low mobility in soil(SRC). The pKa of dipentylamine is 11.16(4), indicating that the protonated form will be the predominant species in moist soils and cations are expected to adsorb strongly to soil surfaces.

With a pKa of 11.16(1), dipentylamine will exist predominantly in its protonated form in the environment and the protonated form of dipentylamine will not volatilize from water or moist soil surfaces(2). Dipentylamine is not expected to volatilize from dry soil surfaces(SRC) based on its vapor pressure of 0.15 mm Hg at 25 °C(3).

Occupational exposure to dipentylamine may occur through inhalation and dermal contact with this compound at workplaces where dipentylamine is produced or used. (SRC)

Environmental effects from the substance have not been investigated adequately.

Dipentylamine's production and use as a rubber accelerator, flotation reagent, dyestuffs and corrosion inhibitor, as a solvent of oils, resins, and some cellulose esters may result in its release to the environment through various waste streams. If released to air, a vapor pressure of 0.15 mm Hg at 25 °C indicates dipentylamine will exist solely as a vapor in the ambient atmosphere. Vapor-phase dipentylamine will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 4 hours. If released to soil, dipentylamine is expected to have low mobility based upon an estimated Koc of 1,800. The pKa of dipentylamine is 11.16, indicating that this compound will exist in the protonated form in the environment and cations generally adsorb more strongly than their neutral counterparts. Volatilization from moist soil surfaces is not expected to be an important fate process because the cation will not volatilize. Dipentylamine is not expected to volatilize from dry soil surfaces based upon its vapor pressure. If released into water, dipentylamine is expected to adsorb to suspended solids and sediment in the water column based upon the estimated Koc. Screening biodegradation studies on other aliphatic amines suggest that dipentylamine may biodegrade in the environment. Volatilization from water surfaces is not expected to be an important fate process since this compound is expected to exist in the protonated form in water surfaces at environmental pH. An estimated BCF of 156 suggests the potential for bioconcentration in aquatic organisms is high. Occupational exposure to dipentylamine may occur through inhalation and dermal contact with this compound at workplaces where dipentylamine is produced or used. (SRC)

Dipentylamine's production and use as a rubber accelerator, flotation reagent, dyestuffs and corrosion inhibitor, and as a solvent of oils, resins, and some cellulose esters(1) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 1,800(SRC) from an estimated log Kow of 3.76(2) and a regression derived equation(3) indicates that dipentylamine is expected to have low mobility in soil(SRC). A pKa value of 11.16(4) indicates that the protonated form of dipentylamine will be the dominant species in moist soil surfaces and cations generally adsorb strongly to soils. Volatilization of dipentylamine from moist soil surfaces is not expected to be an important fate process since the cation will not volatilize. Dipentylamine is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 0.15 mm Hg at 25 °C(5). Screening biodegradation studies on other aliphatic amines(6-11) suggest that dipentylamine may biodegrade in soil(SRC).

AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 1,800(SRC) from an estimated log Kow of 3.76(2) and a regression derived equation(3) indicates that dipentylamine is expected to adsorb to suspended solids and sediment in water(SRC). A pKa value of 11.16(4) indicates that the protonated form of dipentylamine will be the predominant species in water. Volatilization from water surfaces is not expected to be important fate process(SRC) since the protonated form will not volatilize. According to a classification scheme(5), an estimated BCF of 156(SRC), from its log Kow(2) and a regression-derived equation(6), suggests the potential for bioconcentration in aquatic organisms is high(SRC). Screening biodegradation studies on other aliphatic amines(7-12) suggest that dipentylamine may biodegrade in water(SRC).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), dipentylamine, which has a vapor pressure of 0.15 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase dipentylamine is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 4 hours(SRC), from its rate constant of 9X10-11 cu cm/molecule-sec at 25 °C(3). Dipentylamine is not expected to directly photolyze due to the lack of absorption in the environmental UV spectrum(SRC).

No data was found regarding the biodegradation of dipentylamine; however, screening studies on other aliphatic amines(1-6) suggest that dipentylamine may biodegrade in the environment(SRC).

The rate constant for the vapor-phase reaction of dipentylamine with photochemically-produced hydroxyl radicals has been estimated as 9X10-11 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 4 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). Dipentylamine will exist predominantly in the protonated form in the environment based on a pKa value of 11.16(2). Dipentylamine is not expected to directly photolyze due to the lack of absorption in the environmental UV spectrum(SRC).

An estimated BCF of 156 was calculated for dipentylamine(SRC), using an estimated log Kow of 3.76(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is high(SRC).

The Koc of dipentylamine was estimated as 1,800(SRC), using an estimated log Kow of 3.76(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that dipentylamine is expected to have low mobility in soil(SRC). The pKa of dipentylamine is 11.16(4), indicating that the protonated form will be the predominant species in moist soils and cations are expected to adsorb strongly to soil surfaces.

With a pKa of 11.16(1), dipentylamine will exist predominantly in its protonated form in the environment and the protonated form of dipentylamine will not volatilize from water or moist soil surfaces(2). Dipentylamine is not expected to volatilize from dry soil surfaces(SRC) based on its vapor pressure of 0.15 mm Hg at 25 °C(3).

Occupational exposure to dipentylamine may occur through inhalation and dermal contact with this compound at workplaces where dipentylamine is produced or used. (SRC)

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

/GUIDE 131: FLAMMABLE LIQUIDS-TOXIC/ Health: TOXIC; may be fatal if inhaled, ingested or absorbed through skin. Inhalation or contact with some of these materials will irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

/GUIDE 131: FLAMMABLE LIQUIDS-TOXIC/ Fire or Explosion: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion and poison hazard indoors, outdoors or in sewers. Those substances designated with a "P" may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

/GUIDE 131: FLAMMABLE LIQUIDS-TOXIC/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering.

/GUIDE 131: FLAMMABLE LIQUIDS-TOXIC/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.

For more DOT Emergency Guidelines (Complete) data for DIPENTYLAMINE (8 total), please visit the HSDB record page.

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Flammable Liquid Poison

Do not transport with food and feedstuffs.

UN Hazard Class: 3; UN Subsidiary Risks: 6.1; UN Pack Group: III