Mercuric oxide

H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral]

H310 (98.7%): Fatal in contact with skin [Danger Acute toxicity, dermal]

H330 (100%): Fatal if inhaled [Danger Acute toxicity, inhalation]

H373 (100%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

H400 (98.7%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P260, P262, P264, P270, P271, P273, P280, P284, P301+P316, P302+P352, P304+P340, P316, P319, P320, P321, P330, P361+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 78 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

H300: Fatal if swallowed [Danger Acute toxicity, oral]

H311: Toxic in contact with skin [Danger Acute toxicity, dermal]

H315: Causes skin irritation [Warning Skin corrosion/irritation]

H317: May cause an allergic skin reaction [Warning Sensitization, Skin]

H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H360: May damage fertility or the unborn child [Danger Reproductive toxicity]

H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]

H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]

P203, P260, P261, P262, P264, P264+P265, P270, P272, P280, P301+P316, P302+P352, P305+P351+P338, P308+P316, P316, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P361+P364, P362+P364, P405, and P501 (click each P-code to see the statement)

H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P203, P260, P261, P264, P264+P265, P270, P271, P272, P280, P302+P352, P304+P340, P305+P351+P338, P308+P316, P318, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Fresh air, rest. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention .

Signs and Symptoms of Acute Mercuric Oxide Exposure: Signs and symptoms of acute exposure to mercuric oxide may be severe and include increased salivation, foul breath, inflammation and ulceration of the mucous membranes, abdominal pain, and bloody diarrhea. Oliguria (scanty urination), anuria (suppression of urine formation), and acute renal failure may be noted. Weak pulse, seizures, psychic disturbances, circulatory collapse, chest pain, and dyspnea (shortness of breath) may be observed. Dermal exposure may result in dermatitis (red, inflamed skin).

Emergency Life-Support Procedures: Acute exposure to mercuric oxide may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:

1. Move victims to fresh air. Emergency personnel should avoid self-exposure to mercuric oxide.

2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.

3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.

4. RUSH to a health care facility.

Dermal/Eye Exposure:

1. Remove victims from exposure. Emergency personnel should avoid self- exposure to mercuric oxide.

3. Remove contaminated clothing as soon as possible.

4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.

5. Wash exposed skin areas for 15 minutes with soap and water.

6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.

7. RUSH to a health care facility.

Ingestion Exposure:

1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.

2. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.

3. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults, 250 mL (8 oz or 1 cup). Water or milk should be given only if victims are conscious and alert.

4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.

5. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.

6. RUSH to a health care facility. (EPA, 1998)

Wear full body protective clothing and self-contained breathing apparatus.

For small fires, use dry chemical, carbon dioxide, water spray, or foam. For large fires, use water spray, fog, or foam. (EPA, 1998)

In case of fire in the surroundings, use appropriate extinguishing media.

If material involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Use water in flooding quantities as fog. Use foam, dry chemical, or carbon dioxide.

Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Consult an expert! Personal protection: chemical protection suit. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT absorb in saw-dust or other combustible absorbents.

Cleanup: Mercury removal from wastewater can be accomplished by these processes: BMS process; chlorine is added to the wastewater, oxidizing any mercury present to the ionic state. The BMS adsorbent (an activated carbon concentrated of sulfur compound on its surface) is used to collect ionic mercury. The spent adsorbent is then distilled to recover the mercury, leaving a carbon residue for reuse or disposal. TMRIMAC Process: wastewater is fed into a reaction whereby a slight excess of chlorine is maintained, oxidizing any mercury present to ionic mercury. The liquid is then passed through the TMRIMAC ion exchange resin where mercury ions are adsorbed. The mercury is then stripped from the spent resin with hydrochloric acid solution. /Mercury compounds/

Mercury spills should be cleaned up immediately by use of a special vacuum cleaner. Then the area should be washed with a dilute calcium sulfide solution. Small quantities of mercury can be picked up by mixing with copper metal granules. ... /Mercury/

Mercury removal from waste water can be accomplished by these processes: BMS process; Chlorine is added to the waste water, oxidizing any mercury present to the ionic state. The BMS adsorbent (an activated carbon concentrate of sulfur cmpd on its surface) is used to collect ionic mercury. The spent adsorbent is then distilled to recover the mercury, leaving a carbon residue for reuse or disposal. TMR IMAC Process; Waste water is fed into a reactor, whereby a slight excess of chlorine is maintained, oxidizing any mercury present to ionic mercury. The liquid is then passed through the TMR IMAC ion-exchange resin where mercury ions are adsorbed. The mercury is then stripped from the spent resin with hydrochloric acid solution. /Mercury cmpds/

SPILLED MERCURY CMPD OR SOLN CAN BE CLEANED UP BY ANY METHOD THAT DOES NOT CAUSE EXCESSIVE AIRBORNE CONTAMINATION OR SKIN CONTACT. /MERCURY COMPOUNDS/

1) Ventilate area of spill. 2) Collect spilled material for reclamation using commercially available mercury vapor depressants or specialized vacuum cleaners. /Inorganic mercury/

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Disposal: Metal collect all droplets and pools at once by means of suction pump and aspirator bottle with a long capillary tube. Cover fine droplets in nonaccessible cracks with calcium polysulfide and excess sulfur. Combine all contaminated mercury in a tightly stoppered bottle. Hold it for purification or sale. Compounds dissolve all water soluble contaminated compounds. Convert other contaminated compounds to the soluble nitrates. Adjust the acidity and precipitate as mercuric sulfide. Wash and dry the precipitate. Ship to the supplier.

If material not involved in fire: Keep material out of water sources and sewers.

Personnel protection: Avoid breathing dusts, and fumes from burning material. Keep upwind. Avoid bodily contact with the material. ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water. ... If contact with the material anticipated, wear appropriate chemical protective clothing.

Preventative measure: adequate ventilation; careful attention to good housekeeping, e.g., avoidance of spills, and prompt and proper cleaning if a spill occurs; all containers of mercury and its compounds should be kept tightly closed; should be washed on a regular basis with dilute calcium sulfide solution or other suitable reactant; floors should be nonporous; all workers directly involved in the plant operation should shower thoroughly each day before leaving. /Mercury compounds/

Caution : Extreme temperatures (in excess of 932 degrees F) may decompose mercuric oxide into mercury and oxygen. Avoid sources of extreme heat.

Isolate hazard area. Stay upwind; keep out of low areas. Do not touch spilled material. Take up small spills with sand or other non-combustible absorbent material and place into containers for later disposal. For small, dry spills, use clean shovel to place material into clean dry containers. Dike far ahead of large spills for later disposal. (EPA, 1998)

Separated from food and feedstuffs, reducing agents, chlorine and reactive substances. See Chemical Dangers. Keep in the dark. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. Well closed.

PROTECT FROM LIGHT

0.02 [mg/m3], as Hg, inhalable fraction[German Research Foundation (DFG)]

0.081 [mg/m3]

16 [mg/m3]

30 [mg/m3]

0.1 [mg/m3], as Hg

10 mg Hg/m3 (NIOSH, 2024)

10.0 [mg/m3], as Hg

10 mg/cu m (as Hg) /Mercury cmpd (except (organo) alkyl compounds (as Hg)/

0.02 [mg/m3], as Hg

8 hr Time Weighted Avg (TWA): 0.025 mg/cu m, skin /Mercury, elemental and inorganic forms, as Hg/

Excursion Limit Recommendation: Excursions in worker exposure levels may exceed 3 times the TLV-TWA for no more than a total of 30 minutes during a work day, and under no circumstances should they exceed 5 times the TLV-TWA, provided that the TLV-TWA is not exceeded. /Mercury, elemental and inorganic forms, as Hg/

A4: Not classifiable as a human carcinogen. /Mercury, elemental and inorganic forms, as Hg/

Biological Exposure Index (BEI): Determinant: total inorganic mercury in urine; Sampling Time: Prior to shift; BEI: 35 ug/g creatine. The determinant may be present in biological specimens collected from subjects who have not been occupationally exposed, at a concentration which could affect interpretation of the result. Such background concentrations are incorporated in the BEI value. /Mercury/

Biological Exposure Index (BEI): Determinant: total inorganic mercury in blood; Sampling Time: end of shift at end of workweek; BEI: 15 ug/L. The determinant may be present in biological specimens collected from subjects who have not been occupationally exposed, at a concentration which could affect interpretation of the result. Such background concentrations are incorporated in the BEI value. /Mercury/

(as Hg): 0.025 mg/m

(as Hg): 0,02 mg/m

(as Hg, inhalable fraction): 0.02 mg/m

Chronic Inhalation: 0.0002 mg/m3 (L134)

A harmful concentration of airborne particles can be reached quickly when dispersed.

The substance is mildly irritating to the eyes, skin and respiratory tract. The substance may cause effects on the kidneys. Medical observation is indicated.

The substance may have effects on the kidneys, central nervous system and peripheral nervous system. This may result in ataxia, sensory and memory disturbances, tremors, muscle weakness and kidney impairment.

For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)

NO contact with reducing agents.

STRICT HYGIENE!

Avoid inhalation of dust. Use local exhaust or breathing protection.

Protective gloves. Protective clothing.

Wear safety goggles or eye protection in combination with breathing protection.

Do not eat, drink, or smoke during work. Wash hands before eating.

Mercuric oxide, [solid] appears as red or orange-red odorless, dense crystalline powder or scales, yellow when finely powdered. Used as a chemical intermediate for mercury salts, organic mercury compounds, and chlorine monoxide; antiseptic in pharmaceuticals; component of dry cell batteries; pigment and glass modifier; fungicide; preservative in cosmetics; analytical reagent; formerly used in antifouling paints. (EPA, 1998)

Yellow, orange-yellow, or red crystals; Insoluble in water; [ICSC] Powder; [Sigma-Aldrich MSDS]

YELLOW, ORANGE-YELLOW OR RED HEAVY CRYSTALLINE POWDER.

Yellow mercuric oxide: yellow or orange-yellow, heavy, powder, orthorhombic structure

Heavy, bright orange powder

Red mercuric oxide: bright red or orange-red, heavy, crystalline powder or scales; orthorhombic structure; yellow when finely powdered

Odorless

Decomposes at 932 °F (EPA, 1998)

500 °C (decomp)

0.0053 G/100 CC WATER @ 25 °C

0.0395 G/100 CC WATER @ 100 °C

INSOL IN ALCOHOL, ETHER, ACETONE, ALKALI, AMMONIA

Red mercuric oxide: sol in dilute hydrochloric or nitric acid; sol in soln of alkali cyanides or iodides; slowly sol in soln of alkali bromides

For more Solubility (Complete) data for MERCURIC OXIDE (6 total), please visit the HSDB record page.

Solubility in water, mg/l at 20 °C: 50 (very poor)

11.1 at 39 °F (EPA, 1998) - Denser than water; will sink

11.00-11.29 (Red); 11.03 @ 27.5 °C (Yellow)

11.1 g/cm³

11.14 @25 °C

DECOMPOSES ON EXPOSURE TO AIR

RED MERCURIC OXIDE: DECOMP ON EXPOSURE TO LIGHT INTO MERCURY & OXYGEN

WHEN HEATED TO DECOMPOSITION IT EMITS HIGHLY TOXIC FUMES OF MERCURY

INDEX OF REFRACTION: 2.37, 2.5, 2.65

Yellow mercuric oxide: becomes red on heating and yellow again on cooling; more finely divided and more reactive than red mercuric oxide

Red mercuric oxide: @ 400 °C becomes almost black, but red again on cooling

Physical state at 15 °C and 1 atm: solid

Soluble ionized mercuric salts give a yellow precipitate of HgO with NaOH and a red precipitate of HgI2 with alkali iodide. /Soluble mercuric salts/

Metals -> Mercury Compounds, Inorganic

Teratogens

Agrochemicals -> Pesticide active substances

Active substance -> EU Pesticides database: Not approved

No rapid reaction with air. No rapid reaction with water.

Metals, Less Reactive

Oxidizing Agents, Weak

MERCURIC OXIDE is light sensitive. When hydrazine hydrate is dropped on mercuric oxide, an explosion occurs [Mellor 8:318. 1946-47]. Hypophosphorous acid reduces mercuric oxide explosively to the metal [Mellor 4:778. 1946-47]. When heated to decomposition (932 F) it decomposes into mercury and oxygen. Fumes from fire may contain poisonous mercury vapor; oxygen may increase intensity of fire. Explosion of mercuric oxide may occur with friction or application of heat. Avoid reducing agents. Avoid light; may decompose into mercury and oxygen. Fire risk in intimate contact with organic matter.

INCOMPATIBILITIES: BY TRITURATING MERCURIC OXIDE WITH REDUCING AGENTS MERCUROUS CMPD & METALLIC MERCURY MAY BE FORMED. IN PREPN OF OINTMENTS, CONTACT WITH METAL MUST BE AVOIDED. SALTS ARE FORMED WITH MANY ACIDS.

Hypophosphorous acid reduces mercuric oxide explosively to the metal.

HYDROGEN PEROXIDE REACTS VIOLENTLY WITH MERCURIC OXIDE.

CHLORINE REACTS RAPIDLY AT ROOM TEMP WITH MERCURIC OXIDE.

For more Hazardous Reactivities and Incompatibilities (Complete) data for MERCURIC OXIDE (10 total), please visit the HSDB record page.

High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through alterations in intracellular thiol status, mercury can promote oxidative stress, lipid peroxidation, mitochondrial dysfunction, and changes in heme metabolism. Mercury is known to bind to microsomal and mitochondrial enzymes, resulting in cell injury and death. For example, mercury is known to inhibit aquaporins, halting water flow across the cell membrane. It also inhibits the protein LCK, which causes decreased T-cell signalling and immune system depression. Mercury is also believed to inhibit neuronal excitability by acting on the postsynaptic neuronal membrane. It also affects the nervous system by inhibiting protein kinase C and alkaline phosphatase, which impairs brain microvascular formation and function, as well as alters the blood-brain barrier. Mercury also produces an autoimmune response, likely by modification of major histocompatibility complex (MHC) class II molecules, self peptides, T-cell receptors, or cell-surface adhesion molecules. (L7, A8, A25, A26)

A4: Not classifiable as a human carcinogen. /Mercury, elemental and inorganic forms, as Hg/

3, not classifiable as to its carcinogenicity to humans. (L135)

Mercury mainly affects the nervous system. Exposure to high levels of metallic, inorganic, or organic mercury can permanently damage the brain, kidneys, and developing fetus. Effects on brain functioning may result in irritability, shyness, tremors, changes in vision or hearing, and memory problems. Acrodynia, a type of mercury poisoning in children, is characterized by pain and pink discoloration of the hands and feet. Mercury poisoning can also cause Hunter-Russell syndrome and Minamata disease. (L7)

The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

Oral (L136) ; inhalation (L136); dermal (L136)

Cough. Sore throat.

Redness.

Abdominal pain. Nausea. Vomiting. Diarrhoea.

Common symptoms include peripheral neuropathy (presenting as paresthesia or itching, burning or pain), skin discoloration (pink cheeks, fingertips and toes), edema (swelling), and desquamation (dead skin peels off in layers). (A5)

Neurotoxin - Sensorimotor

Nephrotoxin - The chemical is potentially toxic to the kidneys in the occupational setting.

ACGIH Carcinogen - Not Classifiable.

LD50: 18 mg/kg (Oral, Rat) (L428)

Mercury poisoning is treated by immediate decontamination and chelation therapy using DMSA, DMPS, DPCN, or dimercaprol. (A7)

Basic Treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and neat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with available water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . /Mercury and related compounds/

Advanced Treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient with severe pulmonary edema or respiratory arrest. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Mercury and related compounds/

FREQUENT APPLICATIONS TO THE LIDS FOR MANY YEARS HAS INDUCED A BLUISH-GRAY DARKENING OF THE LIDS AND CONJUNCTIVAE. SLIGHT DISCOLORATION HAS ALSO BEEN SEEN IN THE CORNEA IN THE PERIPHERAL PORTIONS OF DESCEMET'S MEMBRANE, & A BROWNISH, LUSTERLESS OPACITY SUPERFICIALLY IN THE PUPILLARY AREA OF THE LENS, BUT WITH NO INTERFERENCE WITH TRANSPARENCY OF THE MEDIA OR DISTURBANCE OF VISUAL ACUITY. IN THE BULBAR CONJUNCTIVA DARK PIGMENT GRANULES MAY BE DISTRIBUTED ABOUT THE BLOOD VESSELS NEAR THE CORNEA. THE DISCOLORATION OF CORNEA AND LENS IS SIMILAR TO THAT WHICH OCCURS IN CHRONIC SYSTEMIC ABSORPTION OF MERCURY. IT APPEARS TO BE HARMLESS AND CAUSES NO SYMPTOMS.

... MERCURY BATTERY WORKERS EXPOSED DAILY TO MERCURIC OXIDE DUST SHOWED 56% WITH URINARY HG VALUES ABOVE THE NORMAL LEVEL OF 250 UG/L WITHOUT CLINICAL SIGNS OF POISONING, AS EVIDENCED BY NORMAL BETA-GLOBULIN LEVELS.

TWO EMPLOYEES IN A MERCURIC OXIDE MFR PLANT DEVELOPED NEUROLOGIC CHANGES NOT PREVIOUSLY REPORTED FROM EXPOSURE TO INORGANIC HG OR ELEMENTAL HG VAPOR. THE SYMPTOMS, PHYSICAL FINDINGS & LAB STUDIES RESEMBLED THOSE FOUND IN AMYOTROPHIC LATERAL SCLEROSIS & ORG HG INTOXICATION.

It is reported that employees at a mercuric oxide production facility associated with battery manufacture have exhibited a variety of symptoms: nervous system disorders, low sperm counts, and loss of weight. The employees may have been exposed to manganese, which may have augmented the reported clinical picture.

DOGS & CATS ARE ... SUSCEPTIBLE TO TOXIC EFFECTS OF MERCURY FROM MERCURIAL OINTMENTS, BOTH DUE TO DIRECT ABSORPTION & TO LICKING OF PARTS TO WHICH THE OINTMENT HAS BEEN APPLIED. POISONING IN CATTLE HAS ALSO BEEN RECORDED AFTER THE USE OF OINTMENTS CONTAINING ... MERCURIC ... YELLOW OXIDE.

... INJECTED EXPTL INTO ANTERIOR CHAMBER /OF EYE/ OF RABBITS HAS BEEN OBSERVED REGULARLY TO CAUSE INFLAMMATION & A PURULENT EXUDATE.

MERCURIC OXIDE (2.16 MG/DAY, ORALLY) TO PREGNANT RATS ON DAY 5 OF PREGNANCY CAUSED CONGENITAL MALFORMATIONS, RUNTING, & LACK OF EYE PIGMENTATION & PUPILS IN 29.7% OF OFFSPRING, BUT 0% MALFORMATIONS IN CONTROLS AFTER DELIVERY ON DAYS 20-21.

A toxicological study of poorly soluble mercury compounds, including mercuric iodide, mercuric ammonium chloride and mercuric oxide indicated that mercuric iodide was the most toxic compound. Acute toxicity study following administration via stomach and single inhalation exposure to rats showed they have approx similar toxicity.

The substance is very toxic to aquatic organisms. Bioaccumulation of this chemical may occur in aquatic organisms. It is strongly advised not to let the chemical enter into the environment.

Environmental fate of mercury and all its cmpd are relevant to mercuric oxide because of photodecomposition of mercuric oxide to mercury.

The substance is very toxic to aquatic organisms. Bioaccumulation of this chemical may occur in aquatic organisms. It is strongly advised not to let the chemical enter into the environment.

Environmental fate of mercury and all its cmpd are relevant to mercuric oxide because of photodecomposition of mercuric oxide to mercury.

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Disposal: Metal collect all droplets and pools at once by means of suction pump and aspirator bottle with a long capillary tube. Cover fine droplets in nonaccessible cracks with calcium polysulfide and excess sulfur. Combine all contaminated mercury in a tightly stoppered bottle. Hold it for purification or sale. Compounds dissolve all water soluble contaminated compounds. Convert other contaminated compounds to the soluble nitrates. Adjust the acidity and precipitate as mercuric sulfide. Wash and dry the precipitate. Ship to the supplier.

/GUIDE 151: SUBSTANCES - TOXIC (Non-combustible)/ Fire or Explosion: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Containers may explode when heated. Runoff may pollute waterways.

/GUIDE 151: SUBSTANCES - TOXIC (Non-combustible)/ Health: Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

/GUIDE 151: SUBSTANCES - TOXIC (Non-combustible)/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas.

/GUIDE 151: SUBSTANCES - TOXIC (Non-combustible)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.

For more DOT Emergency Guidelines (Complete) data for MERCURIC OXIDE (8 total), please visit the HSDB record page.

UN 1641; Mercuric oxide, solid

IMO 6.1; Mercury oxide

49 232 51; Mercuric oxide, solid

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Unbreakable packaging. Put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs. Severe marine pollutant.

Symbol: T+, N; R: 26/27/28-33-50/53; S: (1/2)-13-28-45-60-61; Note: A, 1

UN Hazard Class: 6.1; UN Pack Group: II