| Section 1. Identification | |||
|---|---|---|---|
| Chemical Name | Heptafluorobutyric acid | CAS No. | 375-22-4 |
| Synonyms | perfluorobutyricacid; heptafluorobutyricacid | Chinese Name | 七氟丁酸 |
| Molecular Formula | C4HF7O2 | Molecular Weight | 214.0384 |
| UN No. | — | Data Source | PubChem (NIH/NLM) |
| GHS Hazard Classification | |
|---|---|
| Signal Word | DANGER |
| Pictograms | GHS05 · Corrosive GHS08 · Health Hazard |
| Hazard Statements | H314H318H361 |
| Precautionary Statements | P260P264P264+P265P280P301+P330+P331P302+P361+P354P304+P340P305+P354+P338P316P317P321P363P405P501P203P318 |
| Contents | |||
|---|---|---|---|
| Section 2 | Hazards Identification | Section 8 | Exposure Controls / Personal Protection |
| Section 9 | Physical and Chemical Properties | Section 11 | Toxicological Information |
| Section 12 | Ecological Information | ||
This chemical does not meet GHS hazard criteria for 0.6% (1 of 171) of reports.
H314 (99.4%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
H318 (70.8%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
P260, P264, P264+P265, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P363, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 171 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Reported as not meeting GHS hazard criteria per 1 of 171 reports by companies.
There are 10 notifications provided by 170 of 171 reports by companies with hazard statement code(s).
Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
P203, P280, P318, P405, and P501 (click each P-code to see the statement)
H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]
P264+P265, P280, P305+P354+P338, and P317 (click each P-code to see the statement)
0.37 [mg/m3]
4.0 [mg/m3]
24 [mg/m3]
Colorless liquid with an unpleasant odor; [MSDSonline]
120.8 °C @760 [mm Hg]
1.645 @25 °C
110.8 Ų [M-H-CO2]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: PFAS]
109.53 Ų [M-H-CO2]-
19F nuclear magnetic resonance spectrum
Boiling point
Chemical shift
Diamagnetic susceptibility
Heat of sublimation
Magnetic susceptibility
Optical coefficient
Refractive index
Sound absorption
Sound propagation
Sound velocity
Spin-spin coupling constant
Vapor pressure
Viscosity
Other Classes -> Perfluoroalkyl Acids
Ionic Liquids
Ionic Liquids -> Fluorinated Ionic Liquids
Pesticide -> EPA IRIS
PFAS -> Perfluorocarboxylic acids
PFAS -> Perfluoroalkyl acids (PFAAs)
PFAS -> Other/unspecified
PFAS -> PFAS with analytical method available
PFAS -> Identified in migrating and extractable food contact chemical data
PFAS -> non-polymer
PFAS -> OECD Category
PFAS (C4HF7O2)
PFAS -> PFcarboxylic acids (PFCA)
Perfluorobutanoic Acid (PFBA)
Developmental
Endocrine
1 x 10 ^-3 mg/kg-day
Perfluorobutanoic acid (PFBA)
Smith, C.D. and Nowell, L.H., 2024. Health-Based Screening Levels for evaluating water-quality data (3rd ed.). DOI:10.5066/F71C1TWP
Dermatotoxin - Skin burns.
Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.
IRIS Current
7.80e+01
1.20e+03
1.80e+01
6.50e-03
1.00e-03
Volatile
2.57e+03
2.30e+02
3.50e+03
5.50e+01
7.80e+01
1.20e+03
1.80e+01
6.50e-03
1.00e-03
Volatile
2.57e+03
2.30e+02
3.50e+03
5.50e+01