English Safety Data Sheet Database 中文版 MSDS

Methyl trifluoromethyl ketone

CAS No. 421-50-1 | PubChem CID 9871
Section 1. Identification
Chemical NameMethyl trifluoromethyl ketone CAS No.421-50-1
Synonyms1,1,1-trifluoro-2-propa-none; trifluoroacetone Chinese Name三氟丙酮
Molecular FormulaCH3FO Molecular Weight112.0505
UN No.1993 Data SourcePubChem (NIH/NLM)
GHS Hazard Classification
Signal Word DANGER
Pictograms GHS02 · Flammable GHS05 · Corrosive GHS07 · Irritant
Hazard Statements H224H314H315H318H319H335H412
Precautionary Statements P210P233P240P241P242P243P260P261P264P264+P265P271P273P280P301+P330+P331P302+P352P302+P361+P354P303+P361+P353P304+P340P305+P351+P338P305+P354+P338P316P317P319P321P332+P317P337+P317P362+P364P363P370+P378P403+P233P403+P235P405P501

Section 2. Hazards Identification

H224 (100%): Extremely flammable liquid and vapor [Danger Flammable liquids]

H314 (70%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

H315 (30%): Causes skin irritation [Warning Skin corrosion/irritation]

H318 (68.8%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

H319 (30.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H335 (29.4%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

H412 (69.4%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P271, P273, P280, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P332+P317, P337+P317, P362+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 160 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Section 9. Physical and Chemical Properties

Clear colorless liquid; bp = 22 deg C; [Aldrich MSDS]

728.0 [mmHg]

Schoenflies notation

Chemical bond

Internuclear distance

Molecular structure

Point group

Viscosity

Other Classes -> Halogenated Ketones

PFAS -> PFAS identified in REACH Regulation EC No. 1272/2008

Section 11. Toxicological Information

Lacrimator (Lachrymator) - A substance that irritates the eyes and induces the flow of tears.

Source: PubChem CID 9871 (NIH/NLM, public domain). Retrieved from PubChem, a public-domain chemistry database maintained by the U.S. National Library of Medicine. Last updated: 2026-08-02 09:54:33.
Disclaimer: This information is compiled for reference only and does not replace the manufacturer's official Safety Data Sheet. Always consult the supplier's SDS before handling any chemical.