English Safety Data Sheet Database 中文版 MSDS

1,4-difluorobenzene

CAS No. 540-36-3 | PubChem CID 10892
Section 1. Identification
Chemical Name1,4-difluorobenzene CAS No.540-36-3
Synonymsp-difluorobenzene Chinese Name1,4-二氟苯
Molecular FormulaC6H4F2 Molecular Weight114.09
UN No.1993 Data SourcePubChem (NIH/NLM)
GHS Hazard Classification
Signal Word DANGER
Pictograms GHS02 · Flammable GHS07 · Irritant
Hazard Statements H224H225H319
Precautionary Statements P210P233P240P241P242P243P264+P265P280P303+P361+P353P305+P351+P338P337+P317P370+P378P403+P235P501

Section 2. Hazards Identification

This chemical does not meet GHS hazard criteria for 1.9% (1 of 53) of reports.

H224 (69.8%): Extremely flammable liquid and vapor [Danger Flammable liquids]

H225 (26.4%): Highly Flammable liquid and vapor [Danger Flammable liquids]

H319 (13.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P210, P233, P240, P241, P242, P243, P264+P265, P280, P303+P361+P353, P305+P351+P338, P337+P317, P370+P378, P403+P235, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 53 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria per 1 of 53 reports by companies.

There are 6 notifications provided by 52 of 53 reports by companies with hazard statement code(s).

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Section 9. Physical and Chemical Properties

Liquid with a pungent aromatic odor; [Merck Index] Colorless liquid; [MSDSonline]

13C nuclear magnetic resonance spectrum

Schoenflies notation

Boiling point

Chemical bond

Chemical shift

Excess enthalpy

Heat of solution

Heat of sublimation

Internuclear distance

Mixing enthalpy

Molecular structure

Optical coefficient

Point group

Refractive index

Spin-spin coupling constant

Surface tension

Thermal expansion coefficient

Vapor pressure

Vapor-liquid equilibrium

Viscosity

Other Classes -> Halogenated Monoaromatics

Section 11. Toxicological Information

Neurotoxin - Other CNS neurotoxin

LC50 (mice) = 55,000 mg/m3/2h

Source: PubChem CID 10892 (NIH/NLM, public domain). Retrieved from PubChem, a public-domain chemistry database maintained by the U.S. National Library of Medicine. Last updated: 2026-08-02 08:57:27.
Disclaimer: This information is compiled for reference only and does not replace the manufacturer's official Safety Data Sheet. Always consult the supplier's SDS before handling any chemical.