2-Chloro-1-propene

H224 (100%): Extremely flammable liquid and vapor [Danger Flammable liquids]

H301 (50%): Toxic if swallowed [Danger Acute toxicity, oral]

H311 (47.4%): Toxic in contact with skin [Danger Acute toxicity, dermal]

H315 (48.3%): Causes skin irritation [Warning Skin corrosion/irritation]

H319 (97.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H335 (84.5%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

H336 (11.2%): May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]

P210, P233, P240, P241, P242, P243, P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 116 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Excerpt from ERG Guide 130 [Flammable Liquids (Water-Immiscible / Noxious); polymerization hazard]:

Refer to the "General First Aid" section. Specific First Aid: Wash skin with soap and water. In case of burns, immediately cool affected skin for as long as possible with cold water. Do not remove clothing if adhering to skin. (ERG, 2024)

General First Aid:

· Call 911 or emergency medical service.

· Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.

· Move victim to fresh air if it can be done safely.

· Administer oxygen if breathing is difficult.

· If victim is not breathing:

-- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.

-- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).

-- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.

· Remove and isolate contaminated clothing and shoes.

· For minor skin contact, avoid spreading material on unaffected skin.

· In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.

· For severe burns, immediate medical attention is required.

· Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed.

· Keep victim calm and warm.

· Keep victim under observation.

· For further assistance, contact your local Poison Control Center.

· Note: Basic Life Support (BLS) and Advanced Life Support (ALS) should be done by trained professionals.

Specific First Aid:

· Wash skin with soap and water.

· In case of burns, immediately cool affected skin for as long as possible with cold water. Do not remove clothing if adhering to skin.

Excerpt from ERG Guide 130 [Flammable Liquids (Water-Immiscible / Noxious); polymerization hazard]:

CAUTION: The majority of these products have a very low flash point. Use of water spray when fighting fire may be inefficient.

SMALL FIRE: Dry chemical, CO2, water spray or regular foam. If regular foam is ineffective or unavailable, use alcohol-resistant foam.

LARGE FIRE: Water spray, fog or regular foam. If regular foam is ineffective or unavailable, use alcohol-resistant foam. Avoid aiming straight or solid streams directly onto the product. If it can be done safely, move undamaged containers away from the area around the fire.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn. (ERG, 2024)

If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped or safely confined. Use water in flooding quantities as fog. Solid streams of water may spread fire. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use foam, dry chemical, or carbon dioxide.

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Keep unauthorized personnel away.

· Stay upwind, uphill and/or upstream.

· Ventilate closed spaces before entering, but only if properly trained and equipped.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

· All equipment used when handling the product must be grounded.

· Do not touch or walk through spilled material.

· Stop leak if you can do it without risk.

· Prevent entry into waterways, sewers, basements or confined areas.

· A vapor-suppressing foam may be used to reduce vapors.

· Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers.

· Use clean, non-sparking tools to collect absorbed material.

Large Spill

· Dike far ahead of liquid spill for later disposal.

· Water spray may reduce vapor, but may not prevent ignition in closed spaces.

Excerpt from ERG Guide 130 [Flammable Liquids (Water-Immiscible / Noxious); polymerization hazard]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

LARGE SPILL: Consider initial downwind evacuation for at least 300 meters (1000 feet).

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Immediate precautionary measure

· Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

· Consider initial downwind evacuation for at least 300 meters (1000 feet).

· If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors.

Personnel protection: Avoid breathing vapors. Keep upwind. ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water.

Excerpt from ERG Guide 130 [Flammable Liquids (Water-Immiscible / Noxious); polymerization hazard]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean, non-sparking tools to collect absorbed material.

LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2024)

· Wear positive pressure self-contained breathing apparatus (SCBA).

· Structural firefighters' protective clothing provides thermal protection but only limited chemical protection.

210 [ppm]

2300 [ppm]

3000 [ppm]

CAUTION: The majority of these products have a very low flash point. Use of water spray when fighting fire may be inefficient.

Small Fire

· Dry chemical, CO2, water spray or regular foam. If regular foam is ineffective or unavailable, use alcohol-resistant foam.

Large Fire

· Water spray, fog or regular foam. If regular foam is ineffective or unavailable, use alcohol-resistant foam.

· Avoid aiming straight or solid streams directly onto the product.

· If it can be done safely, move undamaged containers away from the area around the fire.

Fire Involving Tanks, Rail Tank Cars or Highway Tanks

· Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.

· Cool containers with flooding quantities of water until well after fire is out.

· Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.

· ALWAYS stay away from tanks in direct contact with flames.

· For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn.

Excerpt from ERG Guide 130 [Flammable Liquids (Water-Immiscible / Noxious); polymerization hazard]:

Wear positive pressure self-contained breathing apparatus (SCBA). Structural firefighters' protective clothing provides thermal protection but only limited chemical protection. (ERG, 2024)

Personnel protection: ... Wear appropriate chemical protective gloves, boots and goggles. ... Wear positive pressure self-contained breathing apparatus when fighting fires involving this material.

2-chloropropene appears as a clear colorless volatile liquid. Less dense than water and insoluble in water. Vapors heavier than air.

Colorless gas or liquid; [Hawley] Colorless liquid; bp = 22-23 deg C; [MSDSonline]

COLORLESS GAS OR LIQUID

22.6 °C @ 760 MM HG

22.65 °C @760 [mm Hg]

-137.4 °C

-138.6 °C

less than 4 °F (NFPA, 2010)

Flash point < 21 °C

LESS THAN -6 °F (LESS THAN -21 °C) (CLOSED CUP)

INSOL IN WATER; SOL IN ETHER, ACETONE, BENZENE, CHLOROFORM

0.9017 @ 20 °C/4 °C

0.9017 @ 20°C

2.63 (AIR= 1)

819.0 [mmHg]

819 mm Hg at 25 °C /from experimentally-derived coefficients/

819 [mm Hg] @25 °C

Log P = 2.00

INDEX OF REFRACTION: 1.3973 @ 20 °C/D

Coriolis coupling

Schoenflies notation

Boiling point

Centrifugal distortion

Chemical bond

Diamagnetic susceptibility

Dielectric constant

Equilibrium structure

Heat of sublimation

Hindering potential

Internuclear distance

Magnetic susceptibility

Molecular structure

Moment of inertia

Nuclear quadrupole coupling

Nuclear quadrupole moment

Nuclear quadrupole resonance spectroscopy

Optical coefficient

Point group

Quadrupole coupling

Refractive index

Highly flammable. Insoluble in water.

Halogenated Organic Compounds

Hydrocarbons, Aliphatic Unsaturated

Polymerizable Compounds

Highly Flammable

Polymerizable

Halogenated aliphatic compounds, such as 2-CHLOROPROPENE, are moderately or very reactive. Halogenated organics generally become less reactive as more of their hydrogen atoms are replaced with halogen atoms. Low molecular weight haloalkanes are highly flammable and can react with some metals to form dangerous products. Low molecular weight haloalkenes are highly flammable, peroxidizable and may polymerize violently. They may react violently with aluminum. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

Neurotoxin - Acute solvent syndrome

LC50 (mice) = 267,000 mg/m3

SYMPTOMATOLOGY: 1. A. INHALATION, HIGH VAPOR CONCN: GASPING, REFUSAL TO BREATHE, COUGHING, SUBSTERNAL PAIN, & EXTREME RESP DISTRESS @ ... CONCN OVER 1500 PPM. IRRITATION OF EYES & UPPER RESP MUCOSA APPEARS PROMPTLY AFTER EXPOSURE TO CONCENTRATED VAPORS. LACRIMATION AND HEADACHE ARE PROMINENT. COMA MAY OCCUR RAPIDLY. B. INHALATION, LOW VAPOR CONCN: CENTRAL NERVOUS DEPRESSION & MODERATE IRRITATION OF RESP SYSTEM. 2. DERMAL: SEVERE SKIN IRRITATION WITH MARKED INFLAMMATORY RESPONSE OF EPIDERMIS & UNDERLYING TISSUES. /DICHLOROPROPENES/

SYMPTOMATOLOGY: 3. ORAL: ACUTE GI DISTRESS WITH PULMONARY CONGESTION & EDEMA. CNS DEPRESSION, PERHAPS EVEN IN ABSENCE OF IMPAIRED OXYGEN UPTAKE. 4. BY ANY ROUTE, POSSIBLE INJURIES TO LIVER, KIDNEYS & HEART. /DICHLOROPROPENES/

IN A SERIES OF ALLYLIC CHLORO-OLEFINS & THEIR NON-ALLYLIC ISOMERS THE SIGNIFICANCE OF THE ALLYLIC STRUCTURE & THE INFLUENCE OF METHYL & CHLORINE SUBSTITUENTS ON THE DIRECT MUTAGENIC ACTIVITY IN SALMONELLA TYPHIMURIUM (TA 100) WAS TESTED. 2-CHLORO-1-PROPENE DID NOT SHOW ANY DIRECT MUTAGENIC & ALKYLATING PROPERTIES WHEN TESTED ON SALMONELLA TYPHIMURIUM (TA 100).

2-Chloro-1-propene's production and use as a chemical intermediate in organic synthesis and in the formulation of comonomers may result in its release to the environment through various waste streams. 2-Chloro-1-propene may also be released to the environment in waste streams during the production of allyl chloride. If released to the atmosphere, 2-chloro-1-propene will exist solely in the vapor phase in the ambient atmosphere, based on an extrapolated vapor pressure of 819 mm Hg at 25 °C. Vapor-phase 2-chloro-1-propene is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals with an estimated half-life of about 1-2 days. An estimated Koc value of 35 suggests that 2-chloro-1-propene will have very high mobility in soil. Volatilization from moist soil surfaces is expected based on an estimated Henry's Law constant of 7.0X10-2 atm-cu m/mole. Volatilization from dry soil surfaces is expected given the vapor pressure of this compound. Based on limited data, this compound is expected to be resistant to both anaerobic and aerobic biodegradation in soil and water. In anaerobic and aerobic closed bottle tests, using a mixture of 12 chlorinated aliphatic compounds and a methanotroph-conditioned culture inoculum, 10% and 20% removal of 2-chloro-1-propene, respectively, was reported after 60 days incubation. In water, 2-chloro-1-propene is not expected to adsorb to sediment or particulate matter based on its Koc value. This compound should volatilize from water surfaces given its estimated Henry's Law constant. Estimated volatilization half-lives for a model river and model lake are 3 hours and 3 days, respectively. Measured volatilization half-lives in dilute aqueous solution (average solution depth of 6.5 cm) ranged from 29.7 to 35.8 minutes. Bioconcentration in aquatic organisms is expected to be low based on an estimated BCF value of 20. The general population may be exposed to 2-chloro-1-propene via inhalation of ambient air, and dermal contact with vapors and products containing 2-chloro-1-propene. Occupational exposure may occur through inhalation or dermal contact at workplaces where 2-chloro-1-propene is produced or used. (SRC)

2-Chloro-1-propene's production and use as a chemical intermediate in organic synthesis and in the formulation of comonomers(1) may result in its release to the environment through various waste streams(SRC). 2-Chloro-1-propene may also be released to the environment in waste streams(SRC) during the production of allyl chloride(2,3).

TERRESTRIAL FATE: Based on a recommended classification scheme(1), an estimated Koc value of 35(SRC), determined from a structure estimation method(2), indicates that 2-chloro-1-propene will have very high mobility in soil(SRC). Volatilization of 2-chloro-1-propene should be important from moist soil surfaces(SRC) given an estimated Henry's Law constant of 7.0X10-2 atm-cu m/mole(SRC), using a fragment constant estimation method(3). Volatilization from dry soil surfaces(SRC) is expected based on a vapor pressure of 819 mm Hg(SRC), determined from experimentally-derived coefficients(4). Based on limited data, this compound is expected to be resistant to both anaerobic and aerobic biodegradation(SRC). In anaerobic and aerobic closed bottle tests, using a mixture of 12 chlorinated aliphatic compounds and a methanotroph-conditioned culture inoculum, 10% and 20% removal of 2-chloro-1-propene (initially present at 84 ug (anaerobic) and 30 ug (aerobic)), respectively, was reported after 60 days incubation(5).

AQUATIC FATE: Based on a recommended classification scheme(1), an estimated Koc value of 35(SRC), determined from a structure estimation method(2), indicates that 2-chloro-1-propene should not adsorb to suspended solids and sediment in water(SRC). 2-Chloro-1-propene is expected to volatilize from water surfaces(1,SRC) based on an estimated Henry's Law constant of 7.0X10-2 atm-cu m/mole(SRC), developed using a fragment constant estimation method(3). Estimated volatilization half-lives for a model river and model lake are 3 hours and 3 days, respectively(1,SRC). Measured half-lives for 2-chloro-1-propene in dilute (1 ppm, average solution depth of 6.5 cm) aqueous solution ranged from 29.7 to 35.8 minutes(4). According to a classification scheme(5), an estimated BCF value of 20(1,SRC), from a measured log Kow(6), suggests that bioconcentration in aquatic organisms is low(SRC). Based on limited data, this compound is expected to be resistant to both anaerobic and aerobic biodegradation(SRC). In anaerobic and aerobic closed bottle tests, using a mixture of 12 chlorinated aliphatic compounds and a methanotroph-conditioned culture inoculum, 10% and 20% removal of 2-chloro-1-propene (initially present at 84 ug (anaerobic) and 30 ug (aerobic)), respectively, was reported after 60 days incubation(7).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 2-chloro-1-propene, which has a vapor pressure of 819 mm Hg at 25 °C(SRC), from experimentally-derived coefficients(2), will exist solely as a vapor in the ambient atmosphere. Vapor-phase 2-chloro-1-propene is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be about 1-2 days(3,SRC).

A mixture of 12 chlorinated aliphatic compounds, including 2-chloro-1-propene, was evaluated in an aerobic batch-fed reactor; 93.75% of the added 2-chloro-1-propene, initially present at 160 ug/l, was degraded over a 6 month period(1). The same mixture of compounds was evaluated in an anaerobic batch-fed reactor; 82.5% of the added 2-chloro-1-propene was degraded over 6 months(1). In anaerobic and aerobic closed bottle tests, using the same mixture of compounds and a methanotroph-conditioned culture inoculum, 10% and 20% removal of 2-chloro-1-propene (initially present at 84 ug (anaerobic) and 30 ug (aerobic)), respectively, was reported after 60 days incubation(1).

The rate constant for the vapor-phase reaction of 2-chloro-1-propene with photochemically-produced hydroxyl radicals has been estimated as 1.1X10-12 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1,SRC). This corresponds to an atmospheric half-life of about 1-2 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1,SRC).

An estimated BCF value of 20 was calculated for 2-chloro-1-propene(SRC), using a measured log Kow of 2.0(1) and a recommended regression-derived equation(2). According to a classification scheme(3), this BCF value suggests that bioconcentration in aquatic organisms is low(SRC).

Using a structure estimation method based on molecular connectivity indices(1), the Koc for 2-chloro-1-propene can be estimated to be about 35(SRC). According to a recommended classification scheme(2), this estimated Koc value suggests that 2-chloro-1-propene has very high mobility in soil(SRC).

Measured half-lives for 2-chloro-1-propene in dilute (1 ppm, average solution depth of 6.5 cm) aqueous solution ranged from 29.7 to 35.8 minutes(1). The time required for 50 and 90% evaporation of 2-chloro-1-propene from a dilute aqueous solution was 29 and 110 minutes, respectively(2). The Henry's Law constant for 2-chloro-1-propene is estimated as 7.0X10-2 atm-cu m/mole(SRC) using a fragment constant estimation method(3). This value indicates that 2-chloro-1-propene will volatilize rapidly from water surfaces(4,SRC). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec) is estimated as approximately 3 hours(4,SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec) is estimated as approximately 3 days(4,SRC). 2-Chloro-1-propene's values for vapor pressure, 819 mm Hg at 25 °C(SRC), from experimentally-derived coefficients(5), and Henry's Law constant(3,SRC) indicate that volatilization from dry and moist soil surfaces should occur(SRC).

The general population may be exposed to 2-chloro-1-propene via inhalation of ambient air and dermal contact with vapors and products containing 2-chloro-1-propene. Occupational exposure may occur through inhalation or dermal contact at workplaces where 2-chloro-1-propene is produced or used. (SRC)

2-Chloro-1-propene's production and use as a chemical intermediate in organic synthesis and in the formulation of comonomers may result in its release to the environment through various waste streams. 2-Chloro-1-propene may also be released to the environment in waste streams during the production of allyl chloride. If released to the atmosphere, 2-chloro-1-propene will exist solely in the vapor phase in the ambient atmosphere, based on an extrapolated vapor pressure of 819 mm Hg at 25 °C. Vapor-phase 2-chloro-1-propene is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals with an estimated half-life of about 1-2 days. An estimated Koc value of 35 suggests that 2-chloro-1-propene will have very high mobility in soil. Volatilization from moist soil surfaces is expected based on an estimated Henry's Law constant of 7.0X10-2 atm-cu m/mole. Volatilization from dry soil surfaces is expected given the vapor pressure of this compound. Based on limited data, this compound is expected to be resistant to both anaerobic and aerobic biodegradation in soil and water. In anaerobic and aerobic closed bottle tests, using a mixture of 12 chlorinated aliphatic compounds and a methanotroph-conditioned culture inoculum, 10% and 20% removal of 2-chloro-1-propene, respectively, was reported after 60 days incubation. In water, 2-chloro-1-propene is not expected to adsorb to sediment or particulate matter based on its Koc value. This compound should volatilize from water surfaces given its estimated Henry's Law constant. Estimated volatilization half-lives for a model river and model lake are 3 hours and 3 days, respectively. Measured volatilization half-lives in dilute aqueous solution (average solution depth of 6.5 cm) ranged from 29.7 to 35.8 minutes. Bioconcentration in aquatic organisms is expected to be low based on an estimated BCF value of 20. The general population may be exposed to 2-chloro-1-propene via inhalation of ambient air, and dermal contact with vapors and products containing 2-chloro-1-propene. Occupational exposure may occur through inhalation or dermal contact at workplaces where 2-chloro-1-propene is produced or used. (SRC)

2-Chloro-1-propene's production and use as a chemical intermediate in organic synthesis and in the formulation of comonomers(1) may result in its release to the environment through various waste streams(SRC). 2-Chloro-1-propene may also be released to the environment in waste streams(SRC) during the production of allyl chloride(2,3).

TERRESTRIAL FATE: Based on a recommended classification scheme(1), an estimated Koc value of 35(SRC), determined from a structure estimation method(2), indicates that 2-chloro-1-propene will have very high mobility in soil(SRC). Volatilization of 2-chloro-1-propene should be important from moist soil surfaces(SRC) given an estimated Henry's Law constant of 7.0X10-2 atm-cu m/mole(SRC), using a fragment constant estimation method(3). Volatilization from dry soil surfaces(SRC) is expected based on a vapor pressure of 819 mm Hg(SRC), determined from experimentally-derived coefficients(4). Based on limited data, this compound is expected to be resistant to both anaerobic and aerobic biodegradation(SRC). In anaerobic and aerobic closed bottle tests, using a mixture of 12 chlorinated aliphatic compounds and a methanotroph-conditioned culture inoculum, 10% and 20% removal of 2-chloro-1-propene (initially present at 84 ug (anaerobic) and 30 ug (aerobic)), respectively, was reported after 60 days incubation(5).

AQUATIC FATE: Based on a recommended classification scheme(1), an estimated Koc value of 35(SRC), determined from a structure estimation method(2), indicates that 2-chloro-1-propene should not adsorb to suspended solids and sediment in water(SRC). 2-Chloro-1-propene is expected to volatilize from water surfaces(1,SRC) based on an estimated Henry's Law constant of 7.0X10-2 atm-cu m/mole(SRC), developed using a fragment constant estimation method(3). Estimated volatilization half-lives for a model river and model lake are 3 hours and 3 days, respectively(1,SRC). Measured half-lives for 2-chloro-1-propene in dilute (1 ppm, average solution depth of 6.5 cm) aqueous solution ranged from 29.7 to 35.8 minutes(4). According to a classification scheme(5), an estimated BCF value of 20(1,SRC), from a measured log Kow(6), suggests that bioconcentration in aquatic organisms is low(SRC). Based on limited data, this compound is expected to be resistant to both anaerobic and aerobic biodegradation(SRC). In anaerobic and aerobic closed bottle tests, using a mixture of 12 chlorinated aliphatic compounds and a methanotroph-conditioned culture inoculum, 10% and 20% removal of 2-chloro-1-propene (initially present at 84 ug (anaerobic) and 30 ug (aerobic)), respectively, was reported after 60 days incubation(7).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 2-chloro-1-propene, which has a vapor pressure of 819 mm Hg at 25 °C(SRC), from experimentally-derived coefficients(2), will exist solely as a vapor in the ambient atmosphere. Vapor-phase 2-chloro-1-propene is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be about 1-2 days(3,SRC).

A mixture of 12 chlorinated aliphatic compounds, including 2-chloro-1-propene, was evaluated in an aerobic batch-fed reactor; 93.75% of the added 2-chloro-1-propene, initially present at 160 ug/l, was degraded over a 6 month period(1). The same mixture of compounds was evaluated in an anaerobic batch-fed reactor; 82.5% of the added 2-chloro-1-propene was degraded over 6 months(1). In anaerobic and aerobic closed bottle tests, using the same mixture of compounds and a methanotroph-conditioned culture inoculum, 10% and 20% removal of 2-chloro-1-propene (initially present at 84 ug (anaerobic) and 30 ug (aerobic)), respectively, was reported after 60 days incubation(1).

The rate constant for the vapor-phase reaction of 2-chloro-1-propene with photochemically-produced hydroxyl radicals has been estimated as 1.1X10-12 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1,SRC). This corresponds to an atmospheric half-life of about 1-2 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1,SRC).

An estimated BCF value of 20 was calculated for 2-chloro-1-propene(SRC), using a measured log Kow of 2.0(1) and a recommended regression-derived equation(2). According to a classification scheme(3), this BCF value suggests that bioconcentration in aquatic organisms is low(SRC).

Using a structure estimation method based on molecular connectivity indices(1), the Koc for 2-chloro-1-propene can be estimated to be about 35(SRC). According to a recommended classification scheme(2), this estimated Koc value suggests that 2-chloro-1-propene has very high mobility in soil(SRC).

Measured half-lives for 2-chloro-1-propene in dilute (1 ppm, average solution depth of 6.5 cm) aqueous solution ranged from 29.7 to 35.8 minutes(1). The time required for 50 and 90% evaporation of 2-chloro-1-propene from a dilute aqueous solution was 29 and 110 minutes, respectively(2). The Henry's Law constant for 2-chloro-1-propene is estimated as 7.0X10-2 atm-cu m/mole(SRC) using a fragment constant estimation method(3). This value indicates that 2-chloro-1-propene will volatilize rapidly from water surfaces(4,SRC). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec) is estimated as approximately 3 hours(4,SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec) is estimated as approximately 3 days(4,SRC). 2-Chloro-1-propene's values for vapor pressure, 819 mm Hg at 25 °C(SRC), from experimentally-derived coefficients(5), and Henry's Law constant(3,SRC) indicate that volatilization from dry and moist soil surfaces should occur(SRC).

The general population may be exposed to 2-chloro-1-propene via inhalation of ambient air and dermal contact with vapors and products containing 2-chloro-1-propene. Occupational exposure may occur through inhalation or dermal contact at workplaces where 2-chloro-1-propene is produced or used. (SRC)

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

/GUIDE 130P: FLAMMABLE LIQUIDS (Non-Polar/Water-Immiscible/Noxious)/ Fire or Explosion: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

/GUIDE 130P: FLAMMABLE LIQUIDS (Non-Polar/Water-Immiscible/Noxious)/ Health: May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

/GUIDE 130P: FLAMMABLE LIQUIDS (Non-Polar/Water-Immiscible/Noxious)/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering.

/GUIDE 130P: FLAMMABLE LIQUIDS (Non-Polar/Water-Immiscible/Noxious)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Structural firefighters' protective clothing will only provide limited protection.

For more DOT Emergency Guidelines (Complete) data for 2-CHLORO-1-PROPENE (8 total), please visit the HSDB record page.

2456 130P

UN 2456; 2-Chloropropene

IMO 3.1; 2-Chloropropene

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Flammable Liquid