2-nitronaphthalene

H350: May cause cancer [Danger Carcinogenicity]

H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P203, P273, P280, P318, P391, P405, and P501 (click each P-code to see the statement)

H228 (76.5%): Flammable solid [Danger Flammable solids]

H350 (100%): May cause cancer [Danger Carcinogenicity]

H400 (23.5%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

H410 (23.5%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

H411 (76.5%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P203, P210, P240, P241, P273, P280, P318, P370+P378, P391, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 51 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

H228: Flammable solid [Danger Flammable solids]

H303: May be harmful if swallowed [Warning Acute toxicity, oral]

H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]

P203, P210, P240, P241, P280, P301+P317, P318, P370+P378, P405, and P501 (click each P-code to see the statement)

Fresh air, rest. Refer for medical attention.

Rinse and then wash skin with water and soap.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention .

Excerpt from NIOSH Pocket Guide for 2-Nitronaphthalene:

Eye: IRRIGATE IMMEDIATELY - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.

Skin: SOAP WASH IMMEDIATELY - If this chemical contacts the skin, immediately wash the contaminated skin with soap and water. If this chemical penetrates the clothing, immediately remove the clothing, wash the skin with soap and water, and get medical attention promptly.

Breathing: RESPIRATORY SUPPORT - If a person breathes large amounts of this chemical, move the exposed person to fresh air at once. If breathing has stopped, perform artificial respiration. Keep the affected person warm and at rest. Get medical attention as soon as possible.

Swallow: MEDICAL ATTENTION IMMEDIATELY - If this chemical has been swallowed, get medical attention immediately. (NIOSH, 2024)

(General first aid procedures)

Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.

Skin: Soap wash immediately - If this chemical contacts the skin, immediately wash the contaminated skin with soap and water. If this chemical penetrates the clothing, immediately remove the clothing, wash the skin with soap and water, and get medical attention promptly.

Breathing: Respiratory support

Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately.

Excerpt from ERG Guide 133 [Flammable Solids]:

SMALL FIRE: Dry chemical, CO2, sand, earth, water spray or regular foam.

LARGE FIRE: Water spray, fog or regular foam. If it can be done safely, move undamaged containers away from the area around the fire.

FIRE INVOLVING METAL PIGMENTS OR PASTES (E.G. "ALUMINUM PASTE"): Aluminum Paste fires should be treated as a combustible metal fire. Use DRY sand, graphite powder, dry sodium chloride-based extinguishers or class D extinguishers. Also, see ERG Guide 170.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Cool containers with flooding quantities of water until well after fire is out. For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. (ERG, 2024)

Use water in large amounts, foam, alcohol-resistant foam, carbon dioxide.

Excerpt from ERG Guide 133 [Flammable Solids]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area for at least 25 meters (75 feet) in all directions.

LARGE SPILL: Consider initial downwind evacuation for at least 100 meters (330 feet).

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Personal protection: P2 filter respirator for harmful particles.

Excerpt from ERG Guide 133 [Flammable Solids]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. Do not touch or walk through spilled material.

SMALL DRY SPILL: With clean shovel, place material into clean, dry container and cover loosely; move containers from spill area.

LARGE SPILL: Wet down with water and dike for later disposal. Prevent entry into waterways, sewers, basements or confined areas. (ERG, 2024)

Well closed.

Ca* See Appendix A [*Note: Since metabolized to β-Naphthylamine.]

A potential occupational carcinogen. (NIOSH, 2024)

Ca [N.D.]

See: IDLH INDEX

carcinogen category: 2

Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.

The substance may cause effects on the blood. This may result in the formation of methaemoglobin. Medical observation is indicated. The effects may be delayed.

Excerpt from NIOSH Pocket Guide for 2-Nitronaphthalene:

Skin: PREVENT SKIN CONTACT - Wear appropriate personal protective clothing to prevent skin contact.

Eyes: PREVENT EYE CONTACT - Wear appropriate eye protection to prevent eye contact.

Wash skin:

• WHEN CONTAMINATED - The worker should immediately wash the skin when it becomes contaminated.

• DAILY - The worker should wash daily at the end of each work shift, and prior to eating, drinking, smoking, etc.

Remove: WHEN WET OR CONTAMINATED - Work clothing that becomes wet or significantly contaminated should be removed and replaced.

Change: DAILY - Workers whose clothing may have become contaminated should change into uncontaminated clothing before leaving the work premises.

Provide:

• EYEWASH - Eyewash fountains should be provided in areas where there is any possibility that workers could be exposed to the substances; this is irrespective of the recommendation involving the wearing of eye protection.

• QUICK DRENCH - Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure. [Note: It is intended that these facilities provide a sufficient quantity or flow of water to quickly remove the substance from any body areas likely to be exposed. The actual determination of what constitutes an adequate quick drench facility depends on the specific circumstances. In certain instances, a deluge shower should be readily available, whereas in others, the availability of water from a sink or hose could be considered adequate.] (NIOSH, 2024)

At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:

(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode

(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter.

Click here for information on selection of N, R, or P filters.

Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection

NO open flames.

PREVENT DISPERSION OF DUST!

Use local exhaust or breathing protection.

Protective gloves.

Wear safety goggles.

Do not eat, drink, or smoke during work. Wash hands before eating.

2-nitronaphthalene is a yellow crystalline solid. Mp: 76 °C; bp: 315 °C. Insoluble in water. Very soluble in ethyl alcohol and in diethyl ether. Toxic to aquatic organisms, may cause long-term adverse effects in the environment.

Colorless solid; [NIOSH]

COLOURLESS-TO-YELLOW SOLID IN VARIOUS FORMS.

Colorless solid.

174 °F (NIOSH, 2024)

Insoluble (NIOSH, 2024)

Solubility in water: very poor

Insoluble

Relative vapor density (air = 1): 5.89

0.000258 [mmHg]

Vapor pressure, kPa at 25 °C: 0.000032

Chemical shift

Lineshape

Nuclear quadrupole resonance spectroscopy

Quadrupole coupling

Nitrogen Compounds -> Nitros, Aromatic

No rapid reaction with air. No rapid reaction with water.

Nitro, Nitroso, Nitrate, and Nitrite Compounds, Organic

Strong Oxidizing Agent

2-NITRONAPHTHALENE is non-flammable but combustible (flash point 160 °C). Dust forms explosive mixtures with air. Heating or burning releases toxic and corrosive gases. Incompatible with strong oxidizing agents. Can serve as an oxidizing agent and so react with reducing agents such as hydrides, sulfides and nitrides. Such reactions may be vigorous and may culminate in a detonation. May explode in the presence of strong bases such as sodium or potassium hydroxide even in the presence of water or organic solvents.

For "Nitrates" in general: Aluminum, cyanides, esters, phosphorus, tin chlorides, thiocyanates, sodium hypophosphite

2-Nitronaphthalene

Group 3: Not classifiable as to its carcinogenicity to humans

Volume 46: (1989) Diesel and Gasoline Engine Exhausts and Some Nitroarenes

The substance can be absorbed into the body by inhalation and by ingestion.

inhalation, skin absorption, ingestion, skin and/or eye contact

See Ingestion.

Blue lips, fingernails and skin. Confusion. Convulsions. Dizziness. Headache. Nausea. Unconsciousness.

irritation skin, respiratory system; dermatitis; [potential occupational carcinogen]

Skin, respiratory system

[bladder cancer]

Methemoglobinemia - The presence of increased methemoglobin in the blood; the compound is classified as primary toxic effect.

Flammable Solid

Symbol: T, N; R: 45-51/53; S: 53-45-61

UN Hazard Class: 4.1; UN Pack Group: III