Isopropanol

H225: Highly Flammable liquid and vapor [Danger Flammable liquids]

H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]

P210, P233, P240, P241, P242, P243, P261, P264+P265, P271, P280, P303+P361+P353, P304+P340, P305+P351+P338, P319, P337+P317, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]

H373 **: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P260, P264+P265, P273, P280, P305+P354+P338, P317, P319, P391, and P501 (click each P-code to see the statement)

This chemical does not meet GHS hazard criteria for < 0.1% (3 of 8845) of reports.

H225 (> 99.9%): Highly Flammable liquid and vapor [Danger Flammable liquids]

H319 (> 99.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H336 (98.7%): May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]

Aggregated GHS information provided per 8845 reports by companies from 115 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria per 3 of 8845 reports by companies.

There are 114 notifications provided by 8842 of 8845 reports by companies with hazard statement code(s).

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]

H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]

H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

P203, P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P280, P303+P361+P353, P304+P340, P305+P351+P338, P308+P316, P318, P319, P321, P337+P317, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

H303: May be harmful if swallowed [Warning Acute toxicity, oral]

H305: May be harmful if swallowed and enters airways [Warning Aspiration hazard]

H313: May be harmful in contact with skin [Warning Acute toxicity, dermal]

P203, P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P280, P301+P316, P301+P317, P302+P317, P303+P361+P353, P304+P340, P305+P351+P338, P308+P316, P318, P319, P321, P331, P337+P317, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Fresh air, rest. Refer for medical attention.

First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Do NOT induce vomiting. Give nothing to drink. Refer for medical attention .

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. Volatile chemicals have a high risk of being aspirated into the victim's lungs during vomiting which increases the medical problems. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

General First Aid:

· Call 911 or emergency medical service.

· Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.

· Move victim to fresh air if it can be done safely.

· Administer oxygen if breathing is difficult.

· If victim is not breathing:

-- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.

-- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).

-- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.

· Remove and isolate contaminated clothing and shoes.

· For minor skin contact, avoid spreading material on unaffected skin.

· In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.

· For severe burns, immediate medical attention is required.

· Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed.

· Keep victim calm and warm.

· Keep victim under observation.

· For further assistance, contact your local Poison Control Center.

· Note: Basic Life Support (BLS) and Advanced Life Support (ALS) should be done by trained professionals.

Specific First Aid:

· Wash skin with soap and water.

· In case of burns, immediately cool affected skin for as long as possible with cold water. Do not remove clothing if adhering to skin.

In Canada, an Emergency Response Assistance Plan (ERAP) may be required for this product. Please consult the shipping paper and/or the "ERAP" section.

(General first aid procedures)

Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.

Skin: Water flush - If this chemical contacts the skin, flush the contaminated skin with water. Where there is evidence of skin irritation, get medical attention.

Breathing: Respiratory support

Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately.

Excerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:

CAUTION: The majority of these products have a very low flash point. Use of water spray when fighting fire may be inefficient.

SMALL FIRE: Dry chemical, CO2, water spray or alcohol-resistant foam. Do not use dry chemical extinguishers to control fires involving nitromethane (UN1261) or nitroethane (UN2842).

LARGE FIRE: Water spray, fog or alcohol-resistant foam. Avoid aiming straight or solid streams directly onto the product. If it can be done safely, move undamaged containers away from the area around the fire.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn. (ERG, 2024)

Use water, powder, alcohol-resistant foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.

If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use "alcohol" foam, dry chemical or carbon dioxide.

Do not use a solid (straight) water stream as it may scatter and spread fire. /Isopropyl Alcohol, Reagent, ACS/

Since vapor is heavier than air flashback along vapor trail may occur.

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Keep unauthorized personnel away.

· Stay upwind, uphill and/or upstream.

· Ventilate closed spaces before entering, but only if properly trained and equipped.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

· All equipment used when handling the product must be grounded.

· Do not touch or walk through spilled material.

· Stop leak if you can do it without risk.

· Prevent entry into waterways, sewers, basements or confined areas.

· A vapor-suppressing foam may be used to reduce vapors.

· Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers.

· Use clean, non-sparking tools to collect absorbed material.

Large Spill

· Dike far ahead of liquid spill for later disposal.

· Water spray may reduce vapor, but may not prevent ignition in closed spaces.

· Prevent dust cloud.

· For Asbestos, avoid inhalation of dust. Cover spill with plastic sheet or tarp to minimize spreading. Do not clean up or dispose of, except under supervision of a specialist.

Small Dry Spill

· With clean shovel, place material into clean, dry container and cover loosely; move containers from spill area.

Small Spill

· Pick up with sand or other non-combustible absorbent material and place into containers for later disposal.

· Cover powder spill with plastic sheet or tarp to minimize spreading.

Excerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

LARGE SPILL: Consider initial downwind evacuation for at least 300 meters (1000 feet).

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Immediate precautionary measure

· Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

· Consider initial downwind evacuation for at least 300 meters (1000 feet).

· If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

· Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

· For highlighted materials: see Table 1 - Initial Isolation and Protective Action Distances.

· For non-highlighted materials: increase the immediate precautionary measure distance, in the downwind direction, as necessary.

Evacuate danger area! Consult an expert! Remove all ignition sources. Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable non-plastic containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Wash away remainder with plenty of water.

Accidental Release Measures: Personal Precautions: Ensure adequate ventilation. Keep people away from and upwind of spill/leak. Avoid contact with skin, eyes and clothing. Use personal protective equipment. Remove all sources of ignition. Pay attention to flashback. Take precautionary measures against static discharges. All equipment used when handling the product must be grounded. Use spark-proof tools and explosion-proof equipment. In case of large spill, water spray or vapor suppressing foam may be used to reduce vapors, but may not prevent ignition in closed spaces. /Isopropyl Alcohol, Reagent, ACS/

Accidental Release Measures: Environmental Precautions: Prevent further leakage or spillage if safe to do so. Prevent entry into waterways, sewers, basements or confined areas. In case of large spill, dike if needed. Dike far ahead of liquid spill for later disposal. /Isopropyl Alcohol, Reagent, ACS/

Accidental Release Measures: Methods for Cleaning Up: Absorb spill with inert material (e.g. vermiculite, dry sand or earth), then place in a suitable chemical waste container. Clean contaminated surface thoroughly. /Isopropyl Alcohol, Reagent, ACS/

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal and plant life; and conformance with environmental and public health regulations.

SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.

The following wastewater treatment technology has been investigated for isopropanol: Biological treatment.

Excerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean, non-sparking tools to collect absorbed material.

LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2024)

Fireproof. Separated from strong oxidants. Cool. Well closed.

Keep container tightly closed in a dry and well-ventilated place. Store at room temperature in the original container. Sensitive to light. Store in light-resistant containers. Keep away from heat and sources of ignition. Store in a segrated and approved area. Store away from incompatible materials. /Isopropyl Alcohol, Reagent, ACS/

Store in tightly closed containers in a cool, well ventilated area away from heat.

· Wear positive pressure self-contained breathing apparatus (SCBA).

· Structural firefighters' protective clothing provides thermal protection but only limited chemical protection.

Biological Exposure Indices (BEI) [ACGIH] - Acetone in urine = 40 mg/L at end of shift at end of work week;

17693.0 [ppm]

200.0 [ppm]

400 [ppm]

2000 [ppm]

12000 [ppm]

400 ppm (980 mg/m³)

500 ppm (1225 mg/m³)

TWA 400 ppm (980 mg/m3) ST 500 ppm (1225 mg/m3)

400.0 [ppm]

TWA 400 ppm (980 mg/m3) See Appendix G

2000 ppm ; Based on 10% of the lower explosive limit. (NIOSH, 2024)

2000.0 [ppm]

Excerpts from Documentation for IDLHs: Ten volunteers exposed for 3 to 5 minutes to 200, 400, or 800 ppm reported mild to moderate irritation of the eyes, nose, and throat at the two higher concentrations [Nelson et al. 1943].

2000 ppm (Based on 10% of the lower explosive limit for safety considerations even though the relevant toxicological data indicated that irreversible health effects or impairment of escape existed only at higher concentrations.)

2000 ppm

2000 ppm [10%LEL]

See: 67630

8 hr Time Weighted Avg (TWA): 200 ppm; 15 min Short Term Exposure Limit (STEL): 400 ppm

A4; Not classifiable as a human carcinogen.

Biological Exposure Index (BEI): Determinant: acetone in urine; Sampling Time: end of shift at end of workweek; BEI: 40 mg/L. The determinant may be present in biological specimens collected from subjects who have not been occupationally exposed, at a concentration which could affect interpretation of the result. Such background concentrations are incorporated in the BEI value. The determinant is nonspecific, since it is also observed after exposure to other chemicals.

200 ppm as TWA; 400 ppm as STEL; A4 (not classifiable as a human carcinogen); BEI issued.

200 ppm [2001]

400 ppm [2001]

500 mg/m

Intermediate Oral: 1.0 mg/kg/day (L134)

Chronic Oral: 1.0 mg/kg/day (L134)

CAUTION: The majority of these products have a very low flash point. Use of water spray when fighting fire may be inefficient.

Small Fire

· Dry chemical, CO2, water spray or alcohol-resistant foam.

· Do not use dry chemical extinguishers to control fires involving nitromethane (UN1261) or nitroethane (UN2842).

Large Fire

· Water spray, fog or alcohol-resistant foam.

· Avoid aiming straight or solid streams directly onto the product.

· If it can be done safely, move undamaged containers away from the area around the fire.

Fire Involving Tanks, Rail Tank Cars or Highway Tanks

· Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.

· Cool containers with flooding quantities of water until well after fire is out.

· Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.

Volatile, colorless liquid with a sharp musty odor like rubbing alcohol. Flash point of 53 °F. Vapors are heavier than air and mildly irritating to the eyes, nose, and throat. Density approximately 6.5 lb / gal. Used in making cosmetics, skin and hair preparations, pharmaceuticals, perfumes, lacquer formulations, dye solutions, antifreezes, soaps, window cleaners. Sold in 70% aqueous solution as rubbing alcohol.

Liquid; Liquid; Other Solid; Gas Vapor; Dry Powder; Other Solid; Wet Solid; Large Crystals; CBI

Colorless liquid with the odor of rubbing alcohol; [NIOSH]

COLOURLESS LIQUID.

clear, colourless, flammable liquid with a characteristic odour

Colorless liquid with the odor of rubbing alcohol.

Colorless liquid

Pleasant odor

Slight odor resembling that of a mixture of ethanol and acetone

Odor of rubbing alcohol

Slightly bitter taste

Burning taste

180.5 °F at 760 mmHg (NTP, 1992)

82.3 °C at 760 mm Hg

82.0-82.4 °C

82.3 °C @760 [mm Hg]

-127.3 °F (NTP, 1992)

-87.9 °C

53 °F (NTP, 1992)

12 °C, 53 °F (Closed cup)

75 °F (open cup) /91% isopropanol/

11.7 °C c.c.

greater than or equal to 100 mg/mL at 72 °F (NTP, 1992)

Miscible with alcohol, ether, chloroform; insoluble in salt solution

Very soluble in benzene

Miscible with most organic solvents

> 10% in alcohol, ether, and acetone

In water, infinitely soluble at 25 °C

1000.0 mg/mL

Solubility in water: miscible

miscible with water, alcohol, ether and organic solvents

(in ethanol)

Miscible

0.785 at 68 °F (USCG, 1999) - Less dense than water; will float

0.78509 at 25 °C

Freezing point -89.5 °C; forms azeotrope with water (bp 80.37 °C, 760 mm Hg, density 0.83361 at 0 °C/4 °C) /Isopropanol 87.7% (wt/wt)/

% in saturated air: 5.8 (25 °C); density of saturated air: 1.06 (Air = 1); 1 mg/L = 408 ppm and 1 ppm = 2.45 mg/cu m at 25 °C, 760 mm Hg

Coefficient of expansion: 0.00107 per °C; density correction: 0.00082 per °C

Liquid heat capacity: 0.605 BTU/lb-F at 70 °F; Liquid thermal conductivity: 0.937 BTU-in/hr-sq ft-F at 70 °F; Saturated vapor density: 0.00717 lb/cu ft at 70 °F; Ideal gas heat capacity: 0.352 BTU/lb-F at 75 °F

Relative density (water = 1): 0.79

Highly flammable. Water soluble.

Alcohols and Polyols

Highly Flammable

Peroxidizable Compound

ISOPROPANOL reacts with air or oxygen to form dangerously unstable peroxides. Contact with 2-butanone increases the rate of peroxide formation. An explosive reaction occurs when it is heated with (aluminum isopropoxide + crotonaldehyde). Forms explosive mixtures with trinitromethane and hydrogen peroxide. Reacts with barium perchlorate to form a highly explosive compound. Ignites on contact with dioxygenyl tetrafluoroborate, chromium trioxide and potassium-tert-butoxide. Vigorous reactions occur with (hydrogen + palladium), nitroform, oleum, COCl2, aluminum triisopropoxide and oxidizing agents. Reacts explosively with phosgene in the presence of iron salts. Incompatible with acids, acid anhydrides, halogens and aluminum (NTP, 1992). Isopropanol can react with PCl3, forming toxic HCl gas. (Logsdon, John E., Richard A. Loke., "Isopropyl Alcohol." Kirk-Othmer Encyclopedia of Chemical Technology. John Wiley & Sons, Inc. 1996.).

During distillation of 2-propanol recovered from the reduction of crotonaldehyde with aluminium isopropoxide, a violent explosion occurred. This was attributed either to peroxidized diisopropyl ether (a possible by-product) or to peroxidized crotonaldehyde.

Forms explosive mixtures with trinitromethane; hydrogen peroxide (similar in power and sensitivity to glyceryl nitrate). Reacts with barium perchlorate to form the highly explosive propyl perchlorate.

When a stream of hydrogen entrained isopropyl alcohol vapors and palladium particles, the mixture caught fire on exposure to air.

Two explosions occurred during laboratory distillation of isopropanol, one with a sample stored for 4 yr. No cause was apparent, but presence of traces of ketone(s) promoting peroxidation is a possibility. Previously, the presence of 0.36 molar peroxide had been reported in a 99.5% pure sample of isopropanol stored for several months in a partially full clear glass bottle in strong daylight.

For more Hazardous Reactivities and Incompatibilities (Complete) data for ISOPROPANOL (18 total), please visit the HSDB record page.

2-Propanol as a Group B-peroxide-forming solvent is discussed, including the historical literature and the likelihood of peroxide formation in laboratory samples under different storage conditions.

Strong oxidizers, acetaldehyde, chlorine, ethylene oxide, acids, isocyanates

2-Propanol

B*: Compounds that form peroxides on concentration (distillation/evaporation)

28 samples 0-100 ppm 1-&gt;10 yrs (listed as 2-propanol)

Several detonations have occured during laboratory distillations. See Bretherick's for references to specific incidents.

https://cen.acs.org/articles/94/i31/Chemical-safety-peroxide-formation-isopropanol.html

Renfrew, M. M., J. Chem. Educ., 1983, 60(9), A229

Bonafede, J. D., J. Chem. Educ., 1984, 61, 632

Redemann, C. E., J.Amer. Chem. Soc., 1942,64, 3049

Mirafzal, G. A. et al., J. Chem. Educ., 1988, 65(9), A226–229

Bohanon, J. T., Chem. Eng. News, 1989, 67(1),4

Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org

IDENTIFICATION: Isopropyl alcohol is an aliphatic alcohol hydrocarbon. It is prepared from propylene, which is obtained in the cracking of petroleum or by the reduction of acetone. It is a colorless liquid which is soluble in water, alcohol, ether, acetone, benzene and chloroform. It is insoluble in salt solutions. It has a slight odor resembling a mixture of ethanol and acetone and has a slight bitter taste. It is used in antifreeze, industrial solvent, solvent for gums, shellac, essential oils, in quick drying oils, creosote and resins; extraction of alkaloids; in quick drying inks; in denaturing ethyl alcohol; in body rubs, hand lotions, after shave lotions, cosmetics and pharmaceuticals; in manufacture of acetone, glycerol, isopropyl acetate; antiseptic; rubefacient ; and pharmaceutical aid. HUMAN EXPOSURE: Toxic effects include central nervous depression, liver, kidney, cardiovascular depression and brain damage. It can cause drowsiness, ataxia, stupor, coma and respiratory depression, irritation of mucous membranes and eyes, gastritis, gastric hemorrhage, vomiting, pancreatitis, cold clammy skin, hypothermia, miosis, tachycardia, slow and noisy respiration. High risk of circumstances of poisoning: Accidental ingestion of rubbing alcohols/toiletries by children. There is a potential exposure from dermal and inhalation exposure in children during isopropyl alcohol sponging for control of fever. Intentional ingestion for alcoholic effect or in suicide attempts. Occupational or accidental exposure to liquid or its vapor in industrial applications. Individuals exposed to isopropyl alcohol include the following: workers in the pharmaceutical industry, cosmetic industry, chemical industry, petroleum workers, laboratory workers, printers, painters and carpenters and cabinet makers. There is little absorption through intact skin. Isopropyl alcohol is a potent eye and skin irritant. 80% of an oral dose is absorbed within 30 minutes. Absorption is complete within 2 hours although this may be delayed in a large overdose. Alveolar concentration is correlated to the environmental concentration at any given time. Isopropyl alcohol is absorbed through intact skin on prolonged exposure. Isopropyl alcohol distributes in body water with an apparent volume of distribution of 0.6-0.7 L/kg. 20-50% of an absorbed dose is excreted unchanged. Most isopropyl alcohol is oxidized in the liver by alcohol dehydrogenase to acetone, formate and finally carbon dioxide. Acetone is slowly eliminated by the lung (40%) or kidney. Clinically insignificant excretion occurs into the stomach and saliva. Related keto acids are not produced in sufficient quantities to cause a severe metabolic acidosis. Inebriation, peripheral vasodilation has occurred. In children, hypoglycemia is particularly severe when poisoning following fasting, exercise or chronic malnutrition Lactic acidosis may occur in patients with severe liver disease, pancreatitis or receiving biguanide therapy or as a result of the hypovolemia which frequently accompanies severe intoxication. ANIMAL STUDIES: Isopropyl alcohol most closely follows first order kinetics, with a half life of 2.5 to 3.2 hours. The elimination half life of the active metabolite acetone is significantly prolonged to about 5 hours in rats. In rat hepatocytes the following has been observed: marked depletion of glutathione, increased malondialdehyde production, decreased protein sulfhydryls content and leakage of lactic dehydrogenase with loss of membrane activity.

The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphorus. The decreased phosphate body burden results in osteomalacia (softening of the bones due to defective bone mineralization) and rickets. Aluminum's neurotoxicity is believed to involve several mechanisms. Changes in cytoskeletal protein functions as a results of altered phosphorylation, proteolysis, transport, and synthesis are believed to be one cause. Aluminum may induce neurobehavioral effects by affecting permeability of the blood-brain barrier, cholinergic activity, signal transduction pathways, lipid peroxidation, and impair neuronal glutamate nitric oxide-cyclic GMP pathway, as well as interfere with metabolism of essential trace elements because of similar coordination chemistries and consequent competitive interactions. It has been suggested that aluminum's interaction with estrogen receptors increases the expression of estrogen-related genes and thereby contributes to the progression of breast cancer (A235), but studies have not been able to establish a clear link between aluminum and increased risk of breast cancer (A15468). Certain aluminum salts induce immune responses by activating inflammasomes. (L739, A235, A236)

Isopropyl alcohol

Volatile Organic Compound (VOC)

Based on PPRTV; exposure and risk is not significant when compared to the frequent intentional human exposures resulting from non-pesticidal uses

Smith, C.D. and Nowell, L.H., 2024. Health-Based Screening Levels for evaluating water-quality data (3rd ed.). DOI:10.5066/F71C1TWP

Evaluation: There is inadequate evidence for the carcinogenicity of isopropanol in humans. There is inadequate evidence for the carcinogenicity of isopropanol in experimental animals. Overall evaluation: Isopropanol is not classifiable as to its carcinogenicity to humans (Group 3).

A4; Not classifiable as a human carcinogen.

Group 3: Not classifiable as to its carcinogenicity to humans

Volume 15: (1977) Some Fumigants, the Herbicides 2,4-D and 2,4,5-T, Chlorinated Dibenzodioxins and Miscellaneous Industrial Chemicals

Volume Sup 7: Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1 to 42, 1987; 440 pages; ISBN 92-832-1411-0 (out of print)

Volume 71: (1999) Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide (Part 1, Part 2, Part 3)

Not listed by IARC. IARC classified aluminum production as carcinogenic to humans (Group 1), but did not implicate aluminum itself as a human carcinogen. (L135) A link between use of aluminum-containing antiperspirants and increased risk of breast cancer has been proposed (A235), but studies have not been able to establish a clear link (A15468).

3, not classifiable as to its carcinogenicity to humans. (L135)

Aluminum targets the nervous system and causes decreased nervous system performance and is associated with altered function of the blood-brain barrier. The accumulation of aluminum in the body may cause bone or brain diseases. High levels of aluminum have been linked to Alzheimer's disease. A small percentage of people are allergic to aluminium and experience contact dermatitis, digestive disorders, vomiting or other symptoms upon contact or ingestion of products containing aluminium. (L739, L740)

The substance can be absorbed into the body by inhalation of its vapour.

inhalation, ingestion, skin and/or eye contact

Oral (L739) ; inhalation (L739)

Sore throat. Cough. Headache. Dizziness. Drowsiness. Further see Ingestion.

Dry skin.

Redness. Pain. Blurred vision. Burns.

See Inhalation. Abdominal pain. Nausea. Vomiting. Ataxia. Convulsions. Laboured breathing. Low blood pressure. Cardiac dysrhythmia. Unconsciousness.

irritation eyes, nose, throat; drowsiness, dizziness, headache; dry cracking skin; In Animals: narcosis

Inhalating aluminum dust causes coughing and abnormal chest X-rays. A small percentage of people are allergic to aluminium and experience contact dermatitis, digestive disorders, vomiting or other symptoms upon contact or ingestion of products containing aluminium. (L739, L740)

Eyes, skin, respiratory system

Neurotoxin - Acute solvent syndrome

ACGIH Carcinogen - Not Classifiable.

Isopropanol

2 mg/kg-day

2 x 10^-1 mg/m^3

7 mg/m^3

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Inadequate information to assess carcinogenic potential

PPRTV Current

LC50 (rat) = 16,000 ppm/8H

LD50: 11 300 mg/kg (Oral, Rat) (T14)

LC50 Mouse inhalation 53 mg/L 2 hr

LC50 Rat inhalation 51.045 mg/L 8 hr

LC50 Rat inhalation 72.6 mg/L 4 hr

EC50; Species: Daphnia magna (Water Flea) age <24 hr neonate; Conditions: freshwater, static, 21 °C, pH 7.6; Concentration: 114 mM for 24 hr; Effect: intoxication, immobilization

EC50; Species: Daphnia pulex (Water Flea) age <24 hr; Conditions: freshwater, static, 20 °C, pH 7.6; Concentration: 174.27 mM for 24 hr; Effect: intoxication, immobilization /formulation/

LC50; Species: Artemia salina (Brine Shrimp) 2-3 instar larvae; Conditions: saltwater, static, salinity 35 ppt; Concentration: 278000 umol/L for 24 hr /formulation/

LC50; Species: Crangon crangon (Common Shrimp); Conditions: saltwater, renewal; Concentration: 1400000 ug/L for 48 hr (95% confidence interval: 900000-1950000 ug/L) /formulation/

For more Ecotoxicity Values (Complete) data for ISOPROPANOL (32 total), please visit the HSDB record page.

/PLANTS/ Isopropanol inhibited germination of lettuce fruits with an ED50 (median effective dose) of 35 mM.

5.60e+03

2.40e+04

2.10e+02

8.80e+02

4.10e+02

5.00e+01

8.40e-02

2.00e+00

2.00e-01

Volatile

1.09e+05

1.70e+04

7.20e+04

6.30e+02

2.60e+03

1.20e+03

Environmental effects of the substance have been adequately investigated, but no significant effects have been found.

Isopropanol's production and use in the manufacture of acetone, glycerol, and isopropyl acetate and as a solvent for a variety of applications may result in its release to the environment through various waste streams. Isopropanol's use in hydraulic fracturing fluids results in its direct release to the environment. Isopropanol has been identified as a metabolic product of aerobic microorganisms, anaerobic microorganisms, fungi, and yeast. If released to air, a vapor pressure of 45.4 mm Hg at 25 °C indicates isopropanol will exist solely as a vapor in the ambient atmosphere. Vapor-phase isopropanol will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 3.2 days. If released to soil, isopropanol is expected to have very high mobility based upon an estimated Koc of 1.5. Volatilization from moist soil surfaces is expected to be an important fate process based upon a Henry's Law constant of 8.10X10-6 atm-cu m/mole. Isopropanol is expected to volatilize from dry soil surfaces based upon its vapor pressure. If released into water, isopropanol is not expected to adsorb to suspended solids and sediment based upon the estimated Koc. Volatilization from water surfaces is expected to be an important fate process based upon this compound's Henry's Law constant. Estimated volatilization half-lives for a model river and model lake are 86 hours and 29 days, respectively. An estimated BCF of 3 suggests the potential for bioconcentration in aquatic organisms is low. Hydrolysis is not expected to occur due to the lack of hydrolyzable functional groups. Biodegradation is expected to be an important fate process based on the results of microbial screening tests. Occupational exposure to isopropanol may occur through inhalation and dermal contact with this compound at workplaces where isopropanol is produced or used. Monitoring data indicate that the general population may be exposed to isopropanol via inhalation of ambient air, ingestion of food and drinking water, and dermal contact with this compound directly and from consumer products containing isopropanol. (SRC)

Isopropanol has been identified as a metabolic product of aerobic microorganisms (eg, fish spoilage bacteria, beef spoilage bacteria, potato tuber soft rot bacteria), anaerobic microorganisms, fungi (eg, mushrooms), and yeast(1).

Isopropanol's production and use in the manufacture of acetone, glycerol, and isopropyl acetate and as a solvent for a variety of applications(1) may result in its release to the environment through various waste streams(SRC). Isopropanol's use in hydraulic fracturing fluids (2,3) results in its direct release to the environment(SRC). A study of volatile organic compounds in the air of a Swiss tunnel concluded that the isopropanol component was likely due to its use in windshield washer fluids(4).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 1.5(SRC), determined from a structure estimation method(2), indicates that isopropanol is expected to have very high mobility in soil(SRC). Volatilization of isopropanol from moist soil surfaces is expected to be an important fate process(SRC) given a Henry's Law constant of 8.10X10-6 atm-cu m/mole(3). Isopropanol is expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 45.4 mm Hg at 25 °C(4). Isopropanol is reported to be readily degraded in both aerobic and anaerobic conditions(5). Isopropanol was readily degraded in a variety of microbial degradation tests(6-10). Utilizing the Japanese MITI test, 86% of the Theoretical BOD was reached in 2 weeks indicating that biodegradation is an important environmental fate process(10). Acetone has been identified as a metabolite in anaerobic degradation in sludge(11).

AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 1.5(SRC), determined from a structure estimation method(2), indicates that isopropanol is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon a Henry's Law constant of 8.10X10-6 atm-cu m/mole(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 86 hours and 29 days, respectively(SRC). According to a classification scheme(5), an estimated BCF of 3(SRC), from a log Kow(2) and a regression-derived equation(6), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Isopropanol is reported to be readily degraded under both aerobic and anaerobic conditions(7). Isopropanol was readily degraded in a variety of microbial degradation tests(8-12). Utilizing the Japanese MITI test, 86% of the Theoretical BOD was reached in 2 weeks indicating that biodegradation is an important environmental fate process(12). Acetone has been identified as a metabolite in anaerobic degradation(13). Isopropanol is not expected to undergo hydrolysis in the environment due to the lack of hydrolyzable functional groups(3).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), isopropanol, which has a vapor pressure of 45.4 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere(SRC). Vapor-phase isopropanol is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 3.2 days(SRC), calculated from its rate constant of 5.07X10-12 cu cm/molecule-sec at 25 °C(3).

AEROBIC: Degradation of isopropanol with municipal waste water for 5 and 20 days resulted in a theoretical oxygen demand (ThOD) of 7% and 70%, respectively(1). Degradation of 3, 7 and 10 mg/L of isopropanol with filtered sewage seed in fresh water resulted in a ThOD of 28% in 5 days and 78% in 20 days(2). In 2 other studies, the ThOD for isopropanol using domestic waste water was 66% and 74% in 5 days(1). Isopropanol was 99% degraded with acclimated activated sludge at 20 °C (52 mg COD/g-hr rate)(3). Filtered sewage seed resulted in a ThOD of 49% and acclimated sewage seed resulted in a ThOD of 72% after 5 days(4). Degradation of isopropanol with sewage at 20 °C for 5 days resulted in a ThOD of 58% (avg 4 results)(5). In domestic waste water, diluted with salt water, a ThOD of 13% in 5 days and 72% in 20 days was observed(1). Biodegradation of 3, 7, and 10 mg/L of isopropanol with filtered sewage seed in salt water resulted in a ThOD of 13% in 5 days and a ThOD of 72% in 20 days(2). Isopropanol, present at 100 mg/L, reached 86% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test which determined isopropanol to be ready biodegradable(6).

ANAEROBIC: Typical isopropanol removal efficiencies for an anaerobic lagoon treatment facility, with a retention time of 15 days, were 50% after loading with dilute waste, and 69 and 74% after loading with concentrated wastes(1). In closed bottle studies, isopropanol was completely degraded anaerobically by an acetate-enriched culture, derived from a seed of domestic sludge(1). The culture started to use cross-fed isopropanol, after 4 days, at a rate of 200 mg/L/day(1). In a mixed reactor with a 20-day retention time, seeded by the same culture, 56% removal was achieved in the 20 days following 70 days of acclimation to a final concentration of 10,000 mg/L(1). The avg percent removal of isopropanol in semi-pilot scale anaerobic lagoons was 50% in 7.5-10 days for dilute wastes with 60 ppm isopropanol and 69-74% in 20-40 days for concentrated wastes with 175 ppm isopropanol(2). Isopropanol was readily mineralized to methane and carbon dioxide under methanogenic conditions(3). The degradation rate of isopropanol under these conditions in fuel impacted river sediments and industrial/sewage impacted creek sediments was 2.4 ppm C/day (82% of expected methane recovery) and 3.0 ppm C/day (91% of expected methane recovery), respectively(3). The degradation rate of isopropanol in a sediment slurry from a shallow anoxic aquifer under methanogenic conditions was 7.6 ppm C/day (112% of theoretical methane recovery)(4). In anaerobic bioreactor studies using a granular sludge inocula, isopropanol (at 125 ppm initial concentration) degraded with 115.5% of theoretical methane production over a 21-day incubation period(5); acetone was identified as a metabolite(5). In laboratory anaerobic sludge reactor tests using liquid hen manure as inoculum, isopropanol was degraded 100% in a 13-day incubation period with lag period(6).

The rate constant for the vapor-phase reaction of isopropanol with photochemically-produced hydroxyl radicals is 5.07X10-12 cu cm/molecule-sec at 25 °C(1). This corresponds to an atmospheric half-life of about 3.2 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(SRC). Isopropanol is considered to have low reactivity (class 2 of 5 where class 5 is high) in photochemical smog situations(2,3) having an ozone forming potential 68% that of toluene(3). A 20% decrease in isopropanol was observed after 5 hr in a smog chamber at 30 °C containing 2 ppm isopropanol and 1 ppm nitrous oxides at 55% relative humidity(3). The rate constant for the vapor-phase reaction of isopropanol with nitrate radicals in night-time air is 2.3X10-15 cu cm/molecule-sec at 25 °C(4). This corresponds to an atmospheric half-life of about 15 days at a night-time atmospheric concentration of 2.4X10+8 nitrate radicals per cu cm (24-hr average)(5). Isopropanol is not expected to undergo hydrolysis in the environment due to the lack of hydrolyzable functional groups(6). The rate constant for the reaction of isopropanol with hydroxyl radicals in aqueous solution is 1.0X10+9 L/mol-sec(7); this corresponds to an aquatic half-life of about 2.3 years at an aquatic concentration of 1X10-17 hydroxyl radicals per liter(8).

An estimated BCF of 3 was calculated in fish for isopropanol(SRC), using a log Kow of 0.05(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

Using a structure estimation method based on molecular connectivity indices(1), the Koc of isopropanol can be estimated to be 1.5(SRC). According to a classification scheme(2), this estimated Koc value suggests that isopropanol is expected to have very high mobility in soil.

The Henry's Law constant for isopropanol is 8.10X10-6 atm-cu m/mole at 25 °C(1). This Henry's Law constant indicates that isopropanol is expected to volatilize from water surfaces(2). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(2) is estimated as 86 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(2) is estimated as 29 days(SRC). Isopropanol's Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). Isopropanol is expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 45.2 mm Hg at 25 °C(3). The volatilization of isopropanol from a runoff tank of an industrial wastewater treatment facility was measured; the volatilization rate of isopropanol ranged between 0.64-0.69 mg/sq m-min(4). The evaporation rate of a 1:1 isopropanol:water mixture from a shallow pool was 1.5 kg/sq-m per hour at a wind speed of 4.5 m/s and pool temperature of 20 °C and an ambient air temperature of 22 °C(5). Laboratory studies demonstrated that isopropanol will volatilize from water to air in the absence of wind(6).

DRINKING WATER: Isopropanol was detected in trace quantities in some drinking water samples from unspecified sources(1).

SURFACE WATER: Isopropanol was identified but not quantified in the Cuyahoga River, Ohio(1).

In view of the physical properties and the use pattern of isopropanol, the main pathway of entry of this compound into the environment is through its emission into the atmosphere during production, handling, storage, transport, and use, and following waste disposal(1). In the United States, it was estimated that 50% of the production of isopropanol in 1976 was lost into the atmosphere(1). In the Netherlands, an emission factor for the domestic use of isopropanol in aerosol sprays was estimated to be 430 mg/person/day(1). Isopropanol was identified in the volatile emissions from kitchen waste, building materials with microbial growth, and garden waste(2). Isopropanol concentrations of <0.0 to 127 mg/cu m were detected in landfill gas effluents at 7 sites in the UK in 1992-1993(3).

The concentration of isopropanol in leachate from 1 of 5 town landfill sites in Connecticut was 3.4 ppm(1). Isopropanol was found in 6 of 6 leachate samples from Minnesota landfills with a range of concentrations from 94-41,000 ug/L(2). Isopropanol was also found in groundwater suspected of leachate contamination (based on levels of inorganics) at a range of concentrations from 8.6-2600 ug/L (6 of 13 samples pos), but not detected in ground water where inorganics levels indicated good or unknown water quality(2). In 1982-83, isopropanol concentrations of up to 8.8 mg/L were measured in 6 of 7 leachate samples obtained from test wells in 1 of 5 landfills in the United Kingdom(3). The concentration of isopropanol in municipal landfill leachates (complied from 13 sources) was 8.4 mg/L(4).

URBAN/SUBURBAN: The avg concentration of isopropanol in Stockholm (Sweden) between Aug 1982 to Jun 1983 was 14.3 ppb (56 samples, range 2.8-44.0 ppb) and 5.7 ppb (96 samples, range 0.3-33.3 ppb) on 2 busy streets, respectively(1). At 3 locations with moderate to little traffic, the avg concentration of isopropanol was 3.1 ppb (56 samples, range 0.3-10.4 ppb), 0.6 ppb (24 samples, range 0.2-1.6 ppb), and 0.30 ppb (56 samples, range 0.05-1.19 ppb), respectively(1). Urban background levels of isopropanol in Zurich Switzerland air in 2005 was reported as 0.45 ppbV (1st quartile) and 1.49 ppbV (3rd quartile)(2). Outdoor and indoor air was sampled at 75 randomly selected dwellings in Ottawa, Canada during the winter of 2002-2003(3); arithmetic mean isopropanol concentrations of 0.14 and 18.14 ug/cu m were detected in outdoor and indoor air, respectively(3).

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal and plant life; and conformance with environmental and public health regulations.

SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.

The following wastewater treatment technology has been investigated for isopropanol: Biological treatment.

/GUIDE 129: FLAMMABLE LIQUIDS (Polar/Water-Miscible/Noxious)/ Fire or Explosion: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

/GUIDE 129: FLAMMABLE LIQUIDS (Polar/Water-Miscible/Noxious)/ Health: May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

/GUIDE 129: FLAMMABLE LIQUIDS (Polar/Water-Miscible/Noxious)/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering.

/GUIDE 129: FLAMMABLE LIQUIDS (Polar/Water-Miscible/Noxious)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Structural firefighters' protective clothing will only provide limited protection.

For more DOT Emergency Guidelines (Complete) data for ISOPROPANOL (8 total), please visit the HSDB record page.

UN 1219; Isopropanol or Isopropyl alcohol

IMO 3.2; Isopropanol or Isopropyl alcohol

49 092 05; Isopropanol

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Flammable Liquid

UN Hazard Class: 3; UN Pack Group: II