Bromochloromethane

This chemical does not meet GHS hazard criteria for 1.1% (1 of 92) of reports.

H314 (47.8%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

H315 (47.8%): Causes skin irritation [Warning Skin corrosion/irritation]

H318 (82.6%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

H332 (48.9%): Harmful if inhaled [Warning Acute toxicity, inhalation]

H335 (47.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

H420 (87%): Harms public health and the environment by destroying ozone in the upper atmosphere [Warning Hazardous to the ozone layer]

P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P319, P321, P332+P317, P362+P364, P363, P403+P233, P405, P501, and P502 (click each P-code to see the statement)

Aggregated GHS information provided per 92 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria per 1 of 92 reports by companies.

There are 11 notifications provided by 91 of 92 reports by companies with hazard statement code(s).

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

H315: Causes skin irritation [Warning Skin corrosion/irritation]

H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H332: Harmful if inhaled [Warning Acute toxicity, inhalation]

H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]

H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]

H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

H420: Harms public health and the environment by destroying ozone in the upper atmosphere [Warning Hazardous to the ozone layer]

P203, P260, P261, P264, P264+P265, P270, P271, P280, P302+P352, P304+P340, P305+P351+P338, P308+P316, P317, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501, and P502 (click each P-code to see the statement)

H303: May be harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P271, P280, P301+P317, P302+P352, P304+P340, P319, P321, P332+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]

H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P332+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Fresh air, rest. Half-upright position. Administration of oxygen may be needed. Artificial respiration may be needed. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention .

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. Corrosive chemicals will destroy the membranes of the mouth, throat, and esophagus and volatile chemicals have a high risk of being aspirated into the victim's lungs during vomiting. Thus, the risk of increasing the medical problems by inducing vomiting of a volatile corrosive chemical is very high. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

General First Aid:

· Call 911 or emergency medical service.

· Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.

· Move victim to fresh air if it can be done safely.

· Administer oxygen if breathing is difficult.

· If victim is not breathing:

-- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.

-- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).

-- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.

· Remove and isolate contaminated clothing and shoes.

· For minor skin contact, avoid spreading material on unaffected skin.

· In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.

· For severe burns, immediate medical attention is required.

· Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed.

· Keep victim calm and warm.

· Keep victim under observation.

· For further assistance, contact your local Poison Control Center.

· Note: Basic Life Support (BLS) and Advanced Life Support (ALS) should be done by trained professionals.

Specific First Aid:

· Wash skin with soap and water.

(General first aid procedures)

Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.

Skin: Soap wash promptly - If this chemical contacts the skin, promptly wash the contaminated skin with soap and water. If this chemical penetrates the clothing, promptly remove the clothing and wash the skin with soap and water. Get medical attention promptly.

Breathing: Respiratory support

Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately.

Excerpt from ERG Guide 160 [Halogenated Solvents]:

SMALL FIRE: Dry chemical, CO2 or water spray.

LARGE FIRE: Dry chemical, CO2, alcohol-resistant foam or water spray. If it can be done safely, move undamaged containers away from the area around the fire. Dike runoff from fire control for later disposal.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. (ERG, 2024)

In case of fire in the surroundings, use appropriate extinguishing media. In case of fire: keep drums, etc., cool by spraying with water.

Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Advice for firefighters: Wear self-contained breathing apparatus for firefighting if necessary.

If material involved in fire: Cool all affected containers with flooding quantities of water. Use water in flooding quantities as fog. Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Apply water from as far a distance as possible. Keep run off water out of sewers and water sources.

Personnel protection: ... Wear positive pressure self-contained breathing apparatus when fighting fires involving this material.

For more Fire Fighting Procedures (Complete) data for Bromochloromethane (6 total), please visit the HSDB record page.

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Keep unauthorized personnel away.

· Stay upwind, uphill and/or upstream.

· Many gases are heavier than air and will spread along the ground and collect in low or confined areas (sewers, basements, tanks, etc.).

· Ventilate closed spaces before entering, but only if properly trained and equipped.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

· Stop leak if you can do it without risk.

Small Liquid Spill

· Pick up with sand, earth or other non-combustible absorbent material.

Large Spill

· Dike far ahead of liquid spill for later disposal.

· Prevent entry into waterways, sewers, basements or confined areas.

Excerpt from ERG Guide 160 [Halogenated Solvents]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

LARGE SPILL: Consider initial downwind evacuation for at least 100 meters (330 feet).

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Immediate precautionary measure

· Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

· Consider initial downwind evacuation for at least 100 meters (330 feet).

· If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas; Environmental precautions: Do not let product enter drains; Methods and materials for containment and cleaning up: Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal.

1. Ventilate area of spill or leak. 2. Collect for reclamation or absorb in vermiculite, dry sand, earth, or similar material.

Evacuate and restrict persons not wearing protective equipment from area of spill or leak until cleanup is complete. Remove all ignition sources. Ventilate area of spill or leak. Absorb liquids in vermiculite, dry sand, earth, peat, carbon, or a similar material and deposit in sealed containers. It may be necessary to contain and dispose of this chemical as a hazardous waste. If material or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters.

SRP: Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in air, soil or water; effects on animal, aquatic and plant life; and conformance with environmental and public health regulations. If it is possible or reasonable use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination.

Product: Offer surplus and non-recyclable solutions to a licensed disposal company; Contaminated packaging: Dispose of as unused product.

Chlorobromomethane may be disposed of by absorbing it in vermiculite, dry sand, earth, or a similar material, & disposing in a secured landfill.

Incinerate together with flammable solvent in furnace equipped with afterburner and alkali scrubber.

For more Disposal Methods (Complete) data for Bromochloromethane (6 total), please visit the HSDB record page.

Precautions for safe handling: Avoid contact with skin and eyes. Avoid inhalation of vapor or mist.

Appropriate engineering controls: Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

Good industrial hygiene practices recommend that engineering controls be used to reduce environmental concn to the permissible exposure level. However, there are some exceptions where respirators may be used to control exposure. Respirators may be used when engineering & work practice controls are not technically feasible, when such controls are in the process of being installed, or when they fail & need to be supplemented. Respirators may be also used for operations which require entry into tanks or closed vessels, & in emergency situations. ... the only respirators permitted are those that have been approved by Mine Safety & Health Admin or by the National Institute for Occupational Safety & Health. In addition to respirator selection, a complete respiratory protection program should be instituted which includes regular training, maintenance, inspection, cleaning, & evaluation.

For more Preventive Measures (Complete) data for Bromochloromethane (11 total), please visit the HSDB record page.

Excerpt from ERG Guide 160 [Halogenated Solvents]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. Stop leak if you can do it without risk.

SMALL LIQUID SPILL: Pick up with sand, earth or other non-combustible absorbent material.

LARGE SPILL: Dike far ahead of liquid spill for later disposal. Prevent entry into waterways, sewers, basements or confined areas. (ERG, 2024)

Separated from food and feedstuffs, strong oxidizers, strong bases and metals. Ventilation along the floor. Do NOT store or transport in containers made from aluminium or plastic.

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Light sensitive. Storage class (TRGS 510): Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Store in a secure poison location. ... Chlorobromomethane must be stored to avoid contact with chemically active metals, since violent reactions occur. Store in tightly closed containers in a cool, well-ventilated area away from heat.

· Wear positive pressure self-contained breathing apparatus (SCBA).

· Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE.

· Structural firefighters' protective clothing provides thermal protection but only limited chemical protection.

189 [ppm]

830 [ppm]

5000 [ppm]

200 ppm (1050 mg/m³)

TWA 200 ppm (1050 mg/m3)

200.0 [ppm]

2000 ppm (NIOSH, 2024)

2000.0 [ppm]

Excerpts from Documentation for IDLHs: Basis for original (SCP) IDLH: Patty [1963] reported that light narcosis could be produced in animals at 3,000 ppm, and pulmonary edema and deaths during exposure at 27,000 ppm; delayed deaths occurred after exposure to 20,000 ppm [Comstock et al. 1953]. Patty [1963] also reported that guinea pigs survived 1­hour exposures but 1 of 3 guinea pigs died after 2­hour exposures to 8,000 to 10,000 ppm [Matson and Dufour 1948]. . . . Basis for revised IDLH: The revised IDLH for chlorobromomethane is 2,000 ppm based on acute inhalation toxicity data in animals [Comstock et al. 1952; Comstock and Oberst 1953; Matson and Dufour 1948]. This may be a conservative value due to the lack of relevant acute toxicity data for workers.

2000 ppm

See: 74975

8 hr Time Weighted Avg (TWA): 200 ppm.

Excursion Limit Recommendation: Excursions in worker exposure levels may exceed 3 times the TLV-TWA for no more than a total of 30 minutes during a work day, and under no circumstances should they exceed 5 times the TLV-TWA, provided that the TLV-TWA is not exceeded.

200 ppm as TWA.

skin absorption (H); carcinogen category: 3

Small Fire

· Dry chemical, CO2 or water spray.

Large Fire

· Dry chemical, CO2, alcohol-resistant foam or water spray.

· If it can be done safely, move undamaged containers away from the area around the fire.

· Dike runoff from fire control for later disposal.

Fire Involving Tanks, Rail Tank Cars or Highway Tanks

· Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.

· Cool containers with flooding quantities of water until well after fire is out.

· Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.

· ALWAYS stay away from tanks in direct contact with flames.

Monitoring requirements for unregulated contaminants: Contaminant, bromochloromethane; Minimum reporting level, 0.06 ug/L; Period during which monitoring to be completed, 1/1/2013-12/31/2015.

Australia: 200 ppm (1990); Federal Republic of Germany: 200 ppm, short-term level 40 ppm, 30 min, 4 times per shift (1990); United Kingdom: 200 ppm, 10-min STEL 250 ppm (1991).

A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20 °C.

The vapour is irritating to the eyes, skin and respiratory tract. If swallowed the substance may cause vomiting and could result in aspiration pneumonitis. Inhalation of high concentrations of the vapour may cause lung oedema. Exposure at high concentrations could cause lowering of consciousness. Exposure could cause carbon monoxide poisoning. This may result in impaired functions. The effects may be delayed.

Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the central nervous system and liver.

Excerpt from NIOSH Pocket Guide for Chlorobromomethane:

Skin: PREVENT SKIN CONTACT - Wear appropriate personal protective clothing to prevent skin contact.

Eyes: PREVENT EYE CONTACT - Wear appropriate eye protection to prevent eye contact.

Wash skin: WHEN CONTAMINATED - The worker should immediately wash the skin when it becomes contaminated.

Remove: WHEN WET OR CONTAMINATED - Work clothing that becomes wet or significantly contaminated should be removed and replaced.

Change: No recommendation is made specifying the need for the worker to change clothing after the workshift. (NIOSH, 2024)

Bromochloromethane appears as a clear colorless liquid with a sweet chloroform-like odor. Denser than water (density 1.991 g / cm3) and insoluble in water. Hence sinks in water. Boiling point 68 °C. Vapors may cause illness if inhaled. Nonflammable. When exposed to high temperatures may emit toxic fumes. Used as a fire extinguishing agent.

Colorless to pale-yellow liquid with a chloroform-like odor; Note: May be used as a fire extinguishing agent; [NIOSH]

COLOURLESS-TO-YELLOW LIQUID WITH CHARACTERISTIC ODOUR.

Colorless to pale-yellow liquid with a chloroform-like odor.

Colorless to pale-yellow liquid with a chloroform-like odor. [Note: May be used as a fire extinguishing agent.]

Clear, colorless liquid

Colorless to pale-yellow liquid

2100 mg/cu m (odor threshold low); 2100 mg/cu m (odor threshold high) sweet.

Chloroform-like odor

154 °F at 760 mmHg (NTP, 1992)

67.8 °C @760 [mm Hg]

-126 °F (NTP, 1992)

-87.9 °C

No flash or fire points by standard tests in air.

1 to 5 mg/mL at 68 °F (NTP, 1992)

In water, 1.67X10+4 mg/L at 25 °C

0.9 part in 100 parts water

Insoluble in water

Completely miscible with common organic solvents

For more Solubility (Complete) data for Bromochloromethane (8 total), please visit the HSDB record page.

Solubility in water, g/100ml at 20 °C: 0.9 (poor)

Insoluble

1.93 at 77 °F (NTP, 1992) - Denser than water; will sink

1.9344 g/cu cm at 20 °C

Density of saturated air: 1.72 (Air = 1)

Relative density (water = 1): 2.0

1.93 @ 20°C

4.46 (NTP, 1992) - Heavier than air; will sink (Relative to Air)

4.46 (Air = 1)

Relative vapor density (air = 1): 4.5

117 mmHg at 68 °F (NTP, 1992)

142.0 [mmHg]

142 mm Hg at 25 °C

Vapor pressure, kPa at 20 °C: 14.7

115 mmHg

142 [mm Hg] @25 °C

log Kow = 1.41

Chemical stability: Stable under recommended storage conditions. Contains the following stabilizer(s): BHT (<=100 ppm)

Toxic gases & vapors (such as hydrogen chloride, phosgene, carbon monoxide, & hydrogen bromide) may be released when chlorobromomethane decomposes.

When heated to decomposition, it emits toxic fumes of carbon monoxide, carbon dioxide, hydrogen chloride gas, and hydrogen bromide gas.

Insoluble in water.

Halogenated Organic Compounds

BROMOCHLOROMETHANE is sensitive to light (may discolor). Incompatible with strong bases and strong oxidizing agents. Also incompatible with active metals, calcium, aluminum, magnesium, zinc and their alloys. Attacks some forms of plastics, rubber and coatings. (NTP, 1992).

Incompatible materials: Aluminum, Calcium, Magnesium, Zinc, strong bases, strong oxidizing agents

Chemically active metals such as calcium, powdered aluminum, zinc, and magnesium.

Liquid attacks some plastics, rubber, and coatings.

Chemically-active metals such as calcium, powdered aluminum, zinc & magnesium

IDENTIFICATION AND USE: Chlorobromomethane is a colorless to pale-yellow liquid. The major use of chlorobromomethane is as fire-extinguishing fluid, particularly for aircraft and portable systems. It is also used as an explosion suppression agent, as a solvent, and as an intermediate in the manufacture of some insecticides (chlormephos). HUMAN EXPOSURE AND TOXICITY: Symptoms of exposure to chlorobromomethane include disorientation; dizziness; irritation of the skin, eyes and throat; pulmonary edema; headache; anorexia; nausea; vomiting; abdominal pain; weight loss; memory impairment; paralysis; weakness; tremors; convulsions; and CNS depression. It may cause coughing, chest pain, and difficulty in breathing. It may also cause transient corneal epithelium damage. The compound is extremely destructive to tissue of the mucous membranes, upper respiratory tract, eyes, and skin. One firefighter's cornea was injured when a fire extinguisher containing chlorobromomethane and dichlorodifluoromethane was discharged close to his face. Soon thereafter partial loss of corneal epithelium was observed, but deeper layers of cornea remained clear. ANIMAL STUDIES: Exposure of rabbit eyes to a spray of liquid from fire extinguisher containing a mixture of 75% chlorobromomethane plus 25% dichlorodifluoromethane caused transient corneal epithelial injury and conjunctival edema. When applied repeatedly to open skin of rabbits, chlorobromomethane resulted in some hyperemia and exfoliation. When bandaged on, it produced moderate irritation and hyperemia. Concentrations as low as 3000 ppm produced light narcosis in rats. Transient pulmonary edema was observed at concentrations below 27,000 ppm. At higher concentrations, interstitial pneumonitis resulted in delayed deaths. Delayed deaths were also observed after exposure to 20,000 ppm. Deaths during exposure occurred only from exposures above 27,000 ppm. In dogs, acute exposures to high concentrations produced agitation, cardiac arrhythmias, myocardial sensitization to epinephrine, and epileptiform convulsions within 12 min. Chlorobromomethane was mutagenic toward Salmonella typhimurium strains TA100 and TA1535 which contains rat glutathione S-transferase 5-5. Reverse mutations were observed at the tyr locus in Escherichia coli WU361089 exposed at 10 uL/plate without activation. Prophage induction was also observed in E. coli K394 exposed without activation at 10 uL/plate. In an in vitro test with FAF-cells of Chinese hamsters, the compound produced an increase of the sister chromatid exchange frequency.

Bromochloromethane

Volatile Organic Compound (VOC)

Smith, C.D. and Nowell, L.H., 2024. Health-Based Screening Levels for evaluating water-quality data (3rd ed.). DOI:10.5066/F71C1TWP

CLASSIFICATION: D; not classifiable as to human carcinogenicity. BASIS FOR CLASSIFICATION: Based on the lack of data regarding the carcinogenicity of bromochloromethane in humans or animals; however, there are data indicative of genotoxic effects and structural relationships to halogenated methanes classified as B2 probable human carcinogens. HUMAN CARCINOGENICITY DATA: None. ANIMAL CARCINOGENICITY DATA: None.

The substance can be absorbed into the body by inhalation, by ingestion and through the skin.

inhalation, ingestion, skin and/or eye contact

Sore throat. Cough. Nausea. Headache. Shortness of breath. Dizziness. Drowsiness. Unconsciousness.

Dry skin. Redness.

Redness. Pain.

Abdominal pain. Further see Inhalation.

irritation eyes, skin, throat; confusion, dizziness, central nervous system depression; pulmonary edema

Eyes, skin, respiratory system, liver, kidneys, central nervous system

Neurotoxin - Acute solvent syndrome

Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

1 x 10^-1 mg/m^3

PDF Document

Inadequate information to assess carcinogenic potential

SCREEN Current

PPRTV Current

LCLo (rat) = 28,800 ppm/15 min

LC50 Mouse inhalation 3000 ppm/7 hr

LD50 Mouse oral 4300 mg/kg

LD50 Rat oral 5000 mg/kg

LC50 Mouse ihl 15,850 mg/cu m/8 hr

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Halogenated Aliphatic Hydrocarbons and Related Compounds/

Basic treatment: Establish a patent airway (oropharyngeal or nasophayrngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . Cover skin burns with sterile dressings after decontamination ... . /Halogenated Aliphatic Hydrocarbons and Related Compounds/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W TKO. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of cardiac irritability and fluid overload ... . Treat seizures with diazepam (Valium) or lorasepam (Ativan) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Halogenated Aliphatic Hydrocarbons and Related Compounds/

The following medical procedures should be made available to each employee who is exposed to chlorobromomethane at potentially hazardous levels: Initial Medical Screening: Employees should be screened for history of certain medical conditions (listed below) which might place the employee at increased risk from chlorobromomethane. Skin disease: Chlorobromomethane can cause dermatitis on prolonged exposure. Persons with existing skin disorders may be more susceptible to effects of this agent. Liver disease: Although chlorobromomethane is not known as a liver toxin in humans, the importance of this organ in the biotransformation and detoxification of foreign substances should be considered before exposing persons with impaired liver function. Kidney disease: Although chlorobromomethane is not known as a kidney toxin in humans, the importance of this organ in the elimination of toxic substances justifies special consideration in those with impaired renal function. Chronic respiratory disease: In persons with impaired pulmonary function, especially those with obstructive airway disease, the breathing of chlorobromomethane might cause exacerbation of symptoms due to its irritant properties. 2. Periodic medical exam: Any employee developing the above listed conditions should be referred for further medical examination.

/SIGNS AND SYMPTOMS/ Symptoms of exposure to /chlorobromomethane/ include disorientation; dizziness; irritation of the skin, eyes and throat; pulmonary edema; headache; anorexia; nausea; vomiting; abdominal pain; weight loss; memory impairment; paralysis; weakness; tremors; convulsions; and narcosis. It may cause coughing, chest pain, and difficulty in breathing. It may also cause transient corneal epithelium damage.

/CASE REPORTS/ A report ... describes an incident in which three men were grossly exposed during /bromochloromethane/ use and misuse as a military fire extinguisher. All survive, but two required extensive therapy to prevent anesthetic deaths. The third victim, who was sprayed in the face with the liquid for more than 40 s, did not lose consciousness. All subsequently recovered with no evidence of persistent sequelae. Liver biopsies of the first two victims revealed normal microanatomy, and liver function studies were normal a few days after exposure.

/CASE REPORTS/ ... Three cases of acute poisoning in fire fighters using chlorobromomethane as a fire extinguishing agent /are described/. The cases were characterized by "severe headache, loss of consciousness, gastric upsets, weight loss, and slow recovery" but no additional details on exposure concentrations or durations were provided.

/CASE REPORTS/ Cornea was injured ... /when/ fire extinguisher /containing chlorobromomethane & dichlorodifluoromethane/ was discharged close to a person's face. The victim felt the spray of liq & vapor hit his face & eyes, causing immediate severe burning sensation in eyes. Soon thereafter partial loss of corneal epithelium was observed, but deeper layers of cornea remained clear. Conjunctivae & lids were hyperemic & edematous. Discomfort & photophobia gradually subsided ... .

For more Human Toxicity Excerpts (Complete) data for Bromochloromethane (6 total), please visit the HSDB record page.

/LABORATORY ANIMALS: Acute Exposure/ Comparative studies of the acute inhalation toxicities of vaporizable fire-extinguishing agents showed that chlorobromomethane was considerably less toxic than carbon tetrachloride, but was more toxic than the gaseous agents dibromodifluoromethane, bromotrifluoromethane, bromochlorodifluoromethane, and carbon dioxide.

/LABORATORY ANIMALS: Acute Exposure/ The purpose of this study was to determine the conditions causing essentially 100% and 0% mortality after inhalation exposure to bromochloromethane. Male and female rats were exposed for 7 hours at 5,000 ppm of the test substance, 1, 1.5, 2, 4 and 6 hours at 10,000 ppm, 0.3, 0.4, 0.5, 1, 1.5 and 2 hours at 20,000 ppm, 0.1, 0.2, 0.3, 0.4 and 0.6 hours at 40,000 ppm and at 80,000 ppm of the test substance for 0.1 and 0.2 hours. The animals were observed during exposure and until death occurred or until consciousness was regained. The rats were weighed before exposure, the day following exposure and at intervals for two weeks thereafter or until it was apparent that all animals had recovered and were gaining weight normally. No mortality was observed in the 5,000 ppm exposed group. The minimum exposures causing essentially mortality were 2 hours at 10,000 ppm, 0.5 hours at 20,000 ppm, 0.2 hours at >/= 40,000 ppm. Drowsiness was apparent in rats exposed for 7.0 hours to 5,000 ppm. Rats exposed to 10,000 ppm were very drowsy after 1.5 hours and unconscious after two hours. Rats exposed to 20,000 ppm were unconscious at the end of 15 minutes exposure and those exposed to 40,000 ppm were unconscious after six minutes of exposure. With few exceptions, rats that recovered consciousness quickly regained any loss of body weight. On the basis of these results, the inhalative LC0 for bromochloromethane was determined to be 5,000 ppm (26458.81 mg/cu m) after 7-hour exposure period and 10,000 ppm (52917.63 mg/cu m) was determined to be the LC100 for bromochloromethane after 6 hours of inhalation exposure.

/LABORATORY ANIMALS: Acute Exposure/ ... Administration of methylene chlorobromide by stomach tube to mice caused no changes at doses of 500 mg/kg. Single doses of 3000 and 4500 mg/kg were followed by fatty degeneration of the liver and kidneys.

/LABORATORY ANIMALS: Acute Exposure/ Histopathologic examination of tissues /from three inhalation studies/ showed the following: marked visceral congestion; fatty degeneration of the liver, kidney, and occasionally the heart; lipoid depletion of the adrenal cortex; interstitial pneumonitis; and in animals that died, opacity of the eyes.

For more Non-Human Toxicity Excerpts (Complete) data for Bromochloromethane (21 total), please visit the HSDB record page.

EPA has released the Interactive Chemical Safety for Sustainability (iCSS) Dashboard. The iCSS Dashboard provides an interactive tool to explore rapid, automated (or in vitro high-throughput) chemical screening data generated by the Toxicity Forecaster (ToxCast) project and the federal Toxicity Testing in the 21st century (Tox21) collaboration. /The title compound was tested by ToxCast and/or Tox21 assays/[USEPA; ICSS Dashboard Application; Available from, as of December 17, 2015: http://actor.epa.gov/dashboard/]

LC50; Species: Cyprinus carpio (Common Carp) eggs; Conditions: freshwater, static, 26 °C, dissolved oxygen > or =6.8 mg/L; Concentration: 67000 ug/L for 3-5 days (95% confidence interval: 61000-95000 ug/L)

1.50e+02

6.30e+02

4.20e+01

1.80e+02

8.30e+01

6.0E+01(G)

2.10e-02

4.00e-02

Volatile

4.04e+03

4.50e+02

1.90e+03

1.30e+02

5.30e+02

2.50e+02

6.0E+01 (G)

Avoid release to the environment because of its impact on the ozone layer.

Bromochloromethane's production and use as a solvent and chemical intermediate may result its release through various waste streams; its use as a fire extinguishing fluid and explosive suppression agent will result in its direct release to the environment. Several species of marine algae and possibly diatoms naturally release bromochloromethane to the environment. If released to air, a vapor pressure of 142 mm Hg at 25 °C indicates bromochloromethane will exist solely as a vapor in the atmosphere. Vapor-phase bromochloromethane will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 108 days. Bromochloromethane does not absorb light at wavelengths >290 nm and, therefore, is not expected to be susceptible to direct photolysis by sunlight. If released to soil, bromochloromethane is expected to have very high mobility based upon an estimated Koc of 22. Volatilization from moist soil surfaces is expected to be an important fate process based upon an estimated Henry's Law constant of 1.46X10-3 atm-cu m/mole. Bromochloromethane may volatilize from dry soil surfaces based upon its vapor pressure. Utilizing the Japanese MITI test, 0% of the Theoretical BOD was reached in 4 weeks indicating that biodegradation is not an important environmental fate process in soil or water. If released into water, bromochloromethane is not expected to adsorb to suspended solids and sediment based upon the estimated Koc. Volatilization from water surfaces is expected to be an important fate process based upon this compound's estimated Henry's Law constant. Estimated volatilization half-lives for a model river and model lake are 4 hours and 5 days, respectively. An estimated BCF of 4 suggests the potential for bioconcentration in aquatic organisms is low. Hydrolysis is not expected to be an important environmental fate process with an estimated half-life greater than 2.3X10+5 years under environmental conditions (pH 5 to 9). Occupational exposure to bromochloromethane may occur through inhalation and dermal contact with this compound at workplaces where bromochloromethane is produced or used. Monitoring data indicate that the general population may be exposed to bromochloromethane via inhalation of ambient air and ingestion of drinking water and use of fire extinguishers containing this compound. (SRC)

Bromochloromethane was found in remote ocean areas along with other naturally occurring bromo- or chloromethanes produced by algae(1). Bromochloromethane was released from cultivated species of the brown algae, Phaeophyta(2). It is likely that diatoms may also produce bromochloromethane, based on observations of North Sea species(3).

Bromochloromethane's production and use as a solvent and chemical intermediate(1) may result its release through various waste streams; its use as a fire extinguishing fluid and explosive suppression agent(1) will result in its direct release to the environment(SRC). Occurrence in the oceans may also be due to long range transport from anthropogenic sources(2).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 22(SRC), determined from a structure estimation method(2), indicates that bromochloromethane is expected to have very high mobility in soil(SRC). Volatilization of bromochloromethane from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 1.46X10-3 atm-cu m/mole(SRC) based upon its vapor pressure, 142 mm Hg(3), and water solubility, 1.67X10+4 mg/L(4). Bromochloromethane is expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(3). Utilizing the Japanese MITI test, 0% of the Theoretical BOD was reached in 4 weeks(5) indicating that biodegradation is not an important environmental fate process in soil(SRC).

AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 22(SRC), determined from a structure estimation method(2), indicates that bromochloromethane is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon an estimated Henry's Law constant of 1.46X10-3 atm-cu m/mole(SRC), derived from its vapor pressure, 142 mm Hg(4), and water solubility, 1.67X10+4 mg/L(5). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 4 hrs and 5 days, respectively(SRC). According to a classification scheme(6), an estimated BCF of 4(SRC), from its log Kow of 1.41(7) and a regression-derived equation(2), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Utilizing the Japanese MITI test, 0% of the Theoretical BOD was reached in 4 weeks(8) indicating that biodegradation is not an important environmental fate process in water(SRC).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), bromochloromethane, which has a estimated vapor pressure of 142 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase bromochloromethane is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 108 days(SRC), calculated from its rate constant of 8.80X10-14 cu cm/molecule-sec at 25 °C(3). The atmospheric lifetime is further reduced by ocean removal(4). On the basis of its water solubility and assuming that dissolution in the ocean leads to chemical degradation, the atmospheric lifetime will be reduced by approximately a factor of 2(4). Bromochloromethane does not absorb light at wavelengths >290 nm(4) and, therefore, is not expected to be susceptible to direct photolysis by sunlight(SRC).

AEROBIC: Bromochloromethane, present at 100 mg/L, reached 0% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(1). In a screening test, bromochloromethane at an initial concentration of 5 or 10 mg/L underwent 100% degradation within seven days using an adapted settled domestic wastewater inoculum under aerobic conditions(2,3). Complete degradation ensued with 3 successive subcultures(2,3).

ANAEROBIC: Bromochloromethane has been reported to undergo microbial degradation under anoxic conditions when cultured with soil bacteria, although no details were provided(1).

The rate constant for the vapor-phase reaction of bromochloromethane with photochemically-produced hydroxyl radicals is 9.8X10-14 cu cm/molecule-sec at 25 °C(1). This corresponds to an atmospheric half-life of about 108 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(2). A rate constant for the vapor-phase reaction of bromochloromethane with photochemically-produced hydroxyl radicals has also been reported at 1.11X10-13 cu cm/molecule-sec at 25 °C(3), corresponding to an atmospheric half-life of 145 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(2). Bromochloromethane ozone depletion potential has been reported as 0.16(4). A base-catalyzed second-order hydrolysis rate constant of 9.4X10-8 L/mole-sec(SRC) was estimated using a structure estimation method(2); this corresponds to half-lives of 2.3X10-6 yrs and 2.3X10-5 yrs at pH values of 7 and 8, respectively(2). Measurement of bromochloromethane reaction kinetics as a function of pH and temperature indicate that HS- promoted (bisulfide ion produced by microbial reduction of sulfate) reaction exceed hydrolysis rates at HS- concentrations greater than 2-17 uM, well within ranges common in sulfate-reducing environments(5). Therefore, abiotic reaction with bisulfide ions may be of considerable importance in sufate-reducing environments. Bromochloromethane does not absorb light at wavelengths >290 nm(3) and, therefore, is not expected to be susceptible to direct photolysis by sunlight(SRC).

An estimated BCF of 4 was calculated for bromochloromethane(SRC), using a log Kow of 1.41(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low.

Using a structure estimation method based on molecular connectivity indices(1), the Koc of bromochloromethane can be estimated to be 22(SRC). According to a classification scheme(2), this estimated Koc value suggests that bromochloromethane is expected to have very high mobility in soil. The partition coefficient of bromochloromethane between a sandy loam soil and water was 0.2497(3). The electrostatic attraction between negatively charged clay particle and charged carbon atom is hypothesized to be the prime adsorption mechanism of halogenated organic contaminants to a sandy loam. The negative charge on the halogen atoms repels negatively charged soil particles(3).

The Henry's Law constant for bromochloromethane is estimated as 1.46X10-3 atm-cu m/mole(SRC) derived from its vapor pressure, 142 mm Hg(1), and water solubility, 1.67X10+4 mg/L(2). This Henry's Law constant indicates that bromochloromethane is expected to volatilize from water surfaces(3). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(3) is estimated as 4 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(3) is estimated as 5 days(SRC). Bromochloromethane's estimated Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). The potential for volatilization of bromochloromethane from dry soil surfaces may exist(SRC) based upon its vapor pressure(1).

GROUNDWATER: Bromochloromethane was detected in groundwater samples in the Netherlands, at a maximum concentration of 8 ug/L(1). The compound was not detected (minimum reporting limit = 0.044 ug/L) in groundwater samples from 72 wells in Glassoro, NJ, sampled from Sept 1 to Dec 31, 1996(2). Bromochloromethane has a detection frequency of 1.1% of 2948 US wells (0.5 ug/L; max concentration of 17 ug/L) sampled as part of the US Geological Survey conducted between 1985 and 1995(3).

DRINKING WATER: Bromochloromethane was qualitatively detected in Philadelphia's drinking water supply, 1975-1977(1). It was reported as being identified in drinking water(2,3). Bromochloromethane was qualitatively detected in treated, but not raw, drinking water in the UK(4). A municipal water supply in Spain was sampled one week per month between February and June 1987 over which time 315 samples were analyzed(5). The final average and maximum concentrations of bromochloromethane were 9.3 and 152.3 ug/L and the relative frequency of appearance was 59%. Bromochloromethane relative abundance with respect to other halocarbons was 8.6%(5). The compound was not detected in 954 US drinking water sources (579 groundwaters; 375 surface waters; 171 rivers; 204 reservoirs) sampled in the US from May 3, 1999 through October 23, 2000 as part of a US Geological Survey; minium and maximum concentration was <0.2 ug/L(6).

DRINKING WATER: The USEPA Unregulated Contaminant Monitoring Rule (UCMR3) program monitors for 30 contaminants (including bromochloromethane) in PWSs (public water systems)(1). All PWSs serving more than 10,000 people and 800 representative PWSs serving 10,000 or fewer people were monitored beginning in January 2013. The April 2016 Data Summary reports that 4,850 systems contained bronochloromethane, 302 were at or above the minimum reporting level of 0.06 ug/L(2).

SURFACE WATER: Bromochloromethane was detected in 15 out of 91 stations in Lake Ontario at a concentration of trace to 10 ng/L(1). It was detected in 1% of 83 water samples taken from Lake Ontario, 1981(2). The baseline concentration of bromochloromethane in the open Atlantic Ocean is 0.02 ng/L(3). It was qualitatively detected in Narragansett Bay, RI, 1979-81(4). Bromochloromethane was qualitatively detected in rivers in the UK(5). Bromochloromethane was found in one of five samples from the heavily polluted Scheldt estuary in southwest Netherlands (1986-1989) at 0.59 ug/L(6). The compound was not detected in the Evros, Mestos, Strymonas and Axios rivers of Northern Greece sampled seasonally for two years from June 1996 to June 1998; detection limit = 0.03 ug/L(7).

Bromochloromethane was analyzed for but not detected in leachate from reclaimed asphalt pavement collected from six different sites throughout Florida(1).

URBAN/SUBURBAN: Bromochloromethane was not detected (detection limit 1.1 ppb) in 3-hour air samples from 15 U.S. cites during June to September, 1987 during weekdays from 6 to 9 am(1). The concentrations of bromochloromethane in air samples taken at a site 60 km north of Tokyo Japan and at a coastal site to the east was 0.90-1.40 parts per trillion and 0.52-0.64 parts per trillion, respectively(2). Bromochloromethane was tested for but not detected at thirteen air monitoring sites representing urban, communities in the US, sampled in 1996(3).

RURAL/REMOTE: Bromochloromethane was detected at a concentration of 2.3 to 3.1 parts per trillion volume (ground level), 1983, in the arctic at Point Barrow, AL, with the concentration being the greatest during the winter and spring seasons(1). The average concentration of bromochloromethane during the so called arctic haze was 2.3 parts per trillion volume in the haze and 2.0 parts per trillion volume outside the haze(1). The mean concentration of bromochloromethane in air over the open Atlantic (30 deg S to 40 deg N) is 0.4 parts per trillion volume in samples taken below the tropospheric boundary level, and 0.3 parts per trillion volume above that boundary(2). The baseline concentration of this compound in air over the north Atlantic was 0.002 ng/L(2).

SOURCE DOMINATED: Bromochloromethane was qualitatively identified in the air at a hazardous waste site in NJ(1).

Bromochloromethane was detected in steamed southeast Asian crabmeat (Charybdis feriatus) at concentrations of 17.75 (leg), 7.0 (body) and 24.9 (carapace) ug/kg dry sample(1).

Bromochloromethane was detected, not quantified in lava gas and fumarole from Kuju, Satsuma, and Iwojima volcanoes in Japan and the Mt. Etna volcano, Italy(1). The compound has been reported in polar firn air samples from the Antarctic at an average concentration of 0.10 parts per trillion(2).

SRP: Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in air, soil or water; effects on animal, aquatic and plant life; and conformance with environmental and public health regulations. If it is possible or reasonable use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination.

Product: Offer surplus and non-recyclable solutions to a licensed disposal company; Contaminated packaging: Dispose of as unused product.

Chlorobromomethane may be disposed of by absorbing it in vermiculite, dry sand, earth, or a similar material, & disposing in a secured landfill.

Incinerate together with flammable solvent in furnace equipped with afterburner and alkali scrubber.

For more Disposal Methods (Complete) data for Bromochloromethane (6 total), please visit the HSDB record page.

/GUIDE 160 HALOGENATED SOLVENTS/ Fire or Explosion: Some of these materials may burn, but none ignite readily. Most vapors are heavier than air. Air/vapor mixtures may explode when ignited. Container may explode in heat of fire.

/GUIDE 160 HALOGENATED SOLVENTS/ Health: Toxic by ingestion. Vapors may cause dizziness or suffocation. Exposure in an enclosed area may be very harmful. Contact may irritate or burn skin and eyes. Fire may produce irritating and/or toxic gases. Runoff from fire control or dilution water may cause pollution.

/GUIDE 160 HALOGENATED SOLVENTS/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. Keep unauthorized personnel away. Stay upwind. Many gases are heavier than air and will spread along ground and collect in low or confined areas (sewers, basements, tanks). Keep out of low areas. Ventilate closed spaces before entering.

/GUIDE 160 HALOGENATED SOLVENTS/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. Structural firefighters' protective clothing will only provide limited protection.

For more DOT Emergency Guidelines (Complete) data for Bromochloromethane (8 total), please visit the HSDB record page.

UN 1887; Bromochloromethane

IMO 6.1; Bromochloromethane

49 411 18; Bromochloromethane

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials. Bromochloromethane is included on the dangerous goods list.

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article. Bromochloromethane is included on the dangerous goods list.

Do not transport with food and feedstuffs.

UN Hazard Class: 6.1; UN Pack Group: III