Methyl magnesium bromide

H225 (39.7%): Highly Flammable liquid and vapor [Danger Flammable liquids]

H260 (94.5%): In contact with water releases flammable gases which may ignite spontaneously [Danger Substances and mixtures which in contact with water, emit flammable gases]

H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P210, P223, P231+P232, P233, P240, P241, P242, P243, P260, P264, P280, P301+P330+P331, P302+P335+P334, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P321, P363, P370+P378, P402+P404, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 73 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Excerpt from ERG Guide 138 [Substances - Water-Reactive (Emitting Flammable Gases)]:

Refer to the "General First Aid" section. Specific First Aid: In case of contact with substance, wipe from skin immediately; flush skin or eyes with running water for at least 20 minutes. (ERG, 2024)

Excerpt from ERG Guide 138 [Substances - Water-Reactive (Emitting Flammable Gases)]:

DO NOT USE WATER OR FOAM.

SMALL FIRE: Dry chemical, soda ash, lime or sand.

LARGE FIRE: DRY sand, dry chemical, soda ash or lime or withdraw from area and let fire burn. If it can be done safely, move undamaged containers away from the area around the fire.

FIRE INVOLVING METALS OR POWDERS (ALUMINUM, LITHIUM, MAGNESIUM, ETC.): Use dry chemical, DRY sand, sodium chloride powder, graphite powder or class D extinguishers; in addition, for Lithium you may use Lith-X® powder or copper powder. Also, see ERG Guide 170.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. (ERG, 2024)

If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped. Use "alcohol" foam, dry chemical or carbon dioxide. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Do not use water on material itself. /Methyl magnesium bromide in ethyl ether/

Evacuation: If fire becomes uncontrollable or container is exposed to direct flame - consider evacuation of one-third (1/3) mile radius. /Methyl magnesium bromide in ethyl ether/

The solution /methyl magnesium bromide in ethyl ether/ reacts with water to give methane, a flammable gas. The heat of this reaction may be sufficient to ignite the methane. /Methyl magnesium bromide in ethyl ether/

Excerpt from ERG Guide 138 [Substances - Water-Reactive (Emitting Flammable Gases)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

LARGE SPILL: Consider initial downwind evacuation for at least 300 meters (1000 feet).

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Build dikes to contain flow as necessary. Use water spray to knock-down vapors. Do not use water on material itself. /Methyl magnesium bromide in ethyl ether/

Personnel protection: Avoid breathing vapors. Keep upwind. ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water. /Methyl magnesium bromide in ethyl ether/

If material leaking (not on fire) consider evacuation from downwind area based on amount of material spilled, location and weather conditions. /Methyl magnesium bromide in ethyl ether/

Excerpt from ERG Guide 138 [Substances - Water-Reactive (Emitting Flammable Gases)]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material. DO NOT GET WATER on spilled substance or inside containers.

SMALL SPILL: Cover with DRY earth, DRY sand or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain. Dike for later disposal; do not apply water unless directed to do so.

POWDER SPILL: Cover powder spill with plastic sheet or tarp to minimize spreading and keep powder dry. DO NOT CLEAN-UP OR DISPOSE OF, EXCEPT UNDER SUPERVISION OF A SPECIALIST. (ERG, 2024)

...MATERIALS WHICH ARE TOXIC AS STORED OR WHICH CAN DECOMPOSE INTO TOXIC COMPONENTS...SHOULD BE STORED IN A COOL, WELL VENTILATED PLACE, OUT OF THE DIRECT RAYS OF THE SUN, AWAY FROM AREAS OF HIGH FIRE HAZARD, AND SHOULD BE PERIODICALLY INSPECTED. INCOMPATIBLE MATERIALS SHOULD BE ISOLATED... /TOXIC HAZARDS/

1.2 [mg/m3]

13 [mg/m3]

79 [mg/m3]

Excerpt from ERG Guide 138 [Substances - Water-Reactive (Emitting Flammable Gases)]:

Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE. Structural firefighters' protective clothing provides thermal protection but only limited chemical protection. (ERG, 2024)

Personnel protection: ... Wear appropriate chemical protective gloves, boots and goggles. ... /Methyl magnesium bromide in ethyl ether/

Methyl magnesium bromide in ethyl ether appears as a colorless cloudy solution in diethyl ether. Vapors heavier than air.

Diethyl ether solution: Cloudy colorless liquid; [CAMEO] In 1.4m toluene/tetrahydrofuran solution: Orange liquid; [MSDSonline]

Soluble in ether and tetrahydrofuran; insoluble in hydrocarbons

When heated to decomposition it emits acrid smoke and irritating fumes.

Moisture sensitive

... May react violently with water. /Methyl magnesium bromide in ethyl ether/

Metals -> Metals, Organic Compounds

Highly flammable. The solution reacts with water or moisture in the air to form flammable methane gas. The heat from this reaction may be sufficient to ignite the produced methane. Unstable peroxides may form with exposure of the ether to air. This is a slow process.

Metal Hydrides, Metal Alkyls, Metal Aryls, and Silanes

Highly Flammable

Strong Reducing Agent

Water-Reactive

Peroxidizable Compound

Organometallics, such as METHYL MAGNESIUM BROMIDE, are reactive with many other groups. Incompatible with acids and bases. Organometallics are good reducing agents and therefore incompatible with oxidizing agents. Often reactive with water to generate toxic or flammable gases.

...CAN REACT VIGOROUSLY WITH OXIDIZING MATERIALS. /ETHERS/

Dermatotoxin - Skin burns.

Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

UN 3053; Magnesium alkyls

IMO 4.2; Magnesium alkyls

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Dangerous When Wet Flammable Liquid