Phosphorus pentafluoride

H280 (81.8%): Contains gas under pressure; may explode if heated [Warning Gases under pressure]

H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

H330 (100%): Fatal if inhaled [Danger Acute toxicity, inhalation]

P260, P264, P271, P280, P284, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P320, P321, P363, P403+P233, P405, P410+P403, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 143 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Excerpt from ERG Guide 125 [Gases - Toxic and/or Corrosive]:

Refer to the "General First Aid" section. Specific First Aid: In case of contact with liquefied gas, only medical personnel should attempt thawing frosted parts. In case of skin contact with hydrogen fluoride, anhydrous (UN1052), if calcium gluconate gel is available, rinse 5 minutes, then apply gel. Otherwise, continue rinsing until medical treatment is available. (ERG, 2024)

General First Aid:

· Call 911 or emergency medical service.

· Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.

· Move victim to fresh air if it can be done safely.

· Administer oxygen if breathing is difficult.

· If victim is not breathing:

-- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.

-- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).

-- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.

· Remove and isolate contaminated clothing and shoes.

· For minor skin contact, avoid spreading material on unaffected skin.

· In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.

· For severe burns, immediate medical attention is required.

· Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed.

· Keep victim calm and warm.

· Keep victim under observation.

· For further assistance, contact your local Poison Control Center.

· Note: Basic Life Support (BLS) and Advanced Life Support (ALS) should be done by trained professionals.

Specific First Aid:

· In case of contact with liquefied gas, only medical personnel should attempt thawing frosted parts.

· In case of skin contact with hydrogen fluoride, anhydrous (UN1052), if calcium gluconate gel is available, rinse 5 minutes, then apply gel. Otherwise, continue rinsing until medical treatment is available.

In Canada, an Emergency Response Assistance Plan (ERAP) may be required for this product. Please consult the shipping paper and/or the "ERAP" section.

Excerpt from ERG Guide 125 [Gases - Toxic and/or Corrosive]:

SMALL FIRE: Dry chemical or CO2.

LARGE FIRE: Water spray, fog or regular foam. If it can be done safely, move undamaged containers away from the area around the fire. Do not get water inside containers. Damaged cylinders should be handled only by specialists.

FIRE INVOLVING TANKS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Cool containers with flooding quantities of water until well after fire is out. Do not direct water at source of leak or safety devices; icing may occur. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. (ERG, 2024)

If material involved in fire: Do not use water on material itself. Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Do not apply water to point of leak in tank car or container.

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Keep unauthorized personnel away.

· Stay upwind, uphill and/or upstream.

· Many gases are heavier than air and will spread along the ground and collect in low or confined areas (sewers, basements, tanks, etc.).

· Ventilate closed spaces before entering, but only if properly trained and equipped.

· Do not touch or walk through spilled material.

· Stop leak if you can do it without risk.

· If possible, turn leaking containers so that gas escapes rather than liquid.

· Prevent entry into waterways, sewers, basements or confined areas.

· Do not direct water at spill or source of leak.

· Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material.

· Isolate area until gas has dispersed.

Excerpt from ERG Guide 125 [Gases - Toxic and/or Corrosive]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area for at least 100 meters (330 feet) in all directions.

SPILL: See ERG Table 1 - Initial Isolation and Protective Action Distances on the UN/NA 2198 datasheet.

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 1600 meters (1 mile) in all directions; also, consider initial evacuation for 1600 meters (1 mile) in all directions. (ERG, 2024)

Immediate precautionary measure

· Isolate spill or leak area for at least 100 meters (330 feet) in all directions.

· For highlighted materials: see Table 1 - Initial Isolation and Protective Action Distances.

· For non-highlighted materials: increase the immediate precautionary measure distance, in the downwind direction, as necessary.

· If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 1600 meters (1 mile) in all directions; also, consider initial evacuation for 1600 meters (1 mile) in all directions.

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

SRP: Local exhaust ventilation should be applied wherever there is an incidence of point source emissions or dispersion of regulated contaminants in the work area. Ventilation control of the contaminant as close to its point of generation is both the most economical and safest method to minimize personnel exposure to airborne contaminants.

If material not involved in fire: Keep material out of water sources and sewers. Attempt to stop leak if without undue personnel hazard. Do not use water on material itself.

Personnel protection: Avoid breathing vapors. Keep upwind. ... Avoid bodily contact with the material ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water.

Evacuation: If material leaking (not on fire) consider evacuation from downwind area based on amount of material spilled, location and weather conditions.

Excerpt from ERG Guide 125 [Gases - Toxic and/or Corrosive]:

Do not touch or walk through spilled material. Stop leak if you can do it without risk. If possible, turn leaking containers so that gas escapes rather than liquid. Prevent entry into waterways, sewers, basements or confined areas. Do not direct water at spill or source of leak. Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material. Isolate area until gas has dispersed. (ERG, 2024)

MAY BE STORED IN STEEL CYLINDERS.

IN GENERAL, MATERIALS ... TOXIC AS STORED OR WHICH CAN DECOMP INTO TOXIC COMPONENTS DUE TO CONTACT HEAT, MOISTURE, ACIDS OR ACID FUMES, SHOULD BE STORED IN COOL WELL-VENTILATED PLACE, OUT OF ... SUN, AWAY FROM ... FIRE HAZARD & SHOULD BE PERIODICALLY INSPECTED & MONITORED. INCOMPATIBLE MATERIALS SHOULD BE ISOLATED ...

· Wear positive pressure self-contained breathing apparatus (SCBA).

· Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE.

· Structural firefighters' protective clothing provides thermal protection but only limited chemical protection.

TIH (Toxic Inhalation Hazard) - Term used to describe gases and volatile liquids that are toxic when inhaled. Some are TIH materials themselves, e.g., chlorine, and some release TIH gases when spilled in water, e.g., chlorosilanes. [ERG 2016].

1.0 [mg/m3], as F, inhalable fraction[German Research Foundation (DFG)]

3.0 [mg/m3]

30 [mg/m3]

150 [mg/m3]

2.5 [mg/m3], as F

Small Fire

· Dry chemical or CO2.

Large Fire

· Water spray, fog or regular foam.

· If it can be done safely, move undamaged containers away from the area around the fire.

· Do not get water inside containers.

· Damaged cylinders should be handled only by specialists.

Fire Involving Tanks

· Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.

· Cool containers with flooding quantities of water until well after fire is out.

· Do not direct water at source of leak or safety devices; icing may occur.

· Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.

· ALWAYS stay away from tanks in direct contact with flames.

Excerpt from ERG Guide 125 [Gases - Toxic and/or Corrosive]:

Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE. Structural firefighters' protective clothing provides thermal protection but only limited chemical protection. (ERG, 2024)

Phosphorus pentafluoride is a colorless, poisonous, nonflammable, compressed gas with a pungent odor. It is extremely irritating to skin, eyes and mucus membranes. It is very toxic by inhalation and can cause pulmonary edema. Toxic and corrosive fumes are generated when this material is exposed to water or steam. Prolonged exposure of the containers to fire or heat may result in their violent rupturing and rocketing. It is used as a polymerization catalyst.

Colorless gas with an unpleasant odor; [HSDB]

COLORLESS GAS

Unpleasant odor

-84.6 °C

-75 °C @760 [mm Hg]

-93.8 °C

5.805 G/L (GAS)

FUMES STRONGLY IN AIR; HIGH THERMAL STABILITY

WHEN HEATED TO DECOMP, EMITS HIGHLY TOXIC FUMES OF /HYDROGEN FLUORIDE AND PHOSPHORUS OXIDES./

16.7 kJ/mol

TROUTON CONSTANT 21.8; DIPOLE MOMENT 0; DOES NOT ATTACK DRY GLASS EVEN AT 250 °C, BUT A SLIGHT TRACE OF MOISTURE LEADS TO FORMATION OF POTASSIUM OXYTRIFLUORIDE (POF3) AND HYDROGEN FLUORIDE (HF); WATER HYDROLYSIS ULTIMATELY YIELDS PHOSPHORIC ACID; INTERMEDIATES ARE OXYFLUORPHOSPHATES; LEWIS ACID ... FORMS CRYSTALLINE ADDN PRODUCT PHOSPHORUS PENTAFLUORIDE-NITROGEN DIOXIDE (PF5-NO2) AT -10 °C WHICH DISSOCIATES ON WARMING

Reacts immediately with water to hydrolyze, first to POF3 and then to the fluorophosphonic acids.

Heat of fusion 12.1 kJ/mol; Heat of formation 1210 kJ/mol

... Behaves as a Lewis Acid showing electron-accepting properties, generally in a ratio of 1:1 with Lewis bases. It forms complexes with amines, ethers, nitriles, sulfoxides, and other bases.

Toxic Gases & Vapors -> Corrosive Gases

Reactive agents - 2nd degree

Fumes strongly in air, with traces of moisture forming POF3 and HF (corrosive). Decomposed in water or moist air to form phosphoric acid and hydrofluoric Acid, corrosive [Merck 11th ed. 1989].

Acids, Strong Non-oxidizing

Oxidizing Agents, Strong

Halogenating Agents

Water-Reactive

Air-Reactive

PHOSPHORUS PENTAFLUORIDE is a colorless, toxic gas, when exposed to air it strongly fumes. Vigorous reaction with water or steam leads to decomposition (hydrolysis) producing toxic and corrosive fumes. When heated to decomposition it emits toxic fumes of fluoride and oxides of phosphorus [Lewis, 3rd ed., 1993, p. 1034].

Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

Dermatotoxin - Skin burns.

Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.

INTENSELY IRRITATING TO SKIN, EYES, MUCOUS MEMBRANES. INHALATION MAY CAUSE PULMONARY EDEMA.

SYMPTOMATOLOGY: 1. Severe gastritis or gastroenteritis with abdominal pain, retching, and prolonged vomiting, beginning 10-60 min after ingestion. Vomitus may become bloody. Diarrhea is sometimes violent; the feces are watery and later tarry. Dehydration becomes intense. 2. Shock, pallor, cyanosis and coldness. Rapid, weak or imperceptible pulse, low blood pressure, rapid and shallow respirations. 3. Sometimes breathing is deep and rapid, reflecting an accompanying metabolic acidosis. 4. Drowsiness, hyporeflexia, dilated pupils, coma. Vasomotor instability, shock or coma and a serum iron level in great excess of the total iron-binding capacity are poor prognostic signs. /Fluoride/

SYMPTOMATOLOGY: 5. Liver injury, consisting of hemorrhagic necrosis which is usually reversible. 6. Death from shock, usually in 4-5 hr. Sometimes following apparent recovery, pneumonia with fever or secondary shock may cause death 1-3 days later. 7. Among survivors pyloric stenosis and mild hepatic cirrhosis may be encountered as persistent sequelae, but recovery is usually complete. /Fluoride/

Corrosive to eyes and skin.

INHALATION MAY CAUSE PULMONARY EDEMA.

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

If ... THERE IS NO FIRE, go directly to the Table of Initial Isolation and Protective Action Distances /(see table below)/ ... to obtain initial isolation and protective action distances. IF THERE IS A FIRE, or IF A FIRE IS INVOLVED, go directly to the appropriate guide /(see guide(s) below)/ and use the evacuation information shown under PUBLIC SAFETY. /Phosphorus pentafluoride; Phosphorus pentafluoride, compressed/

Table: Table of Isolation and Protective Action Distances for Phosphorus pentafluoride [Table#3074]

/GUIDE 125: GASES - CORROSIVE/ Health: TOXIC; may be fatal if inhaled, ingested or absorbed through skin. Vapors are extremely irritating and corrosive. Contact with gas or liquefied gas may cause burns, severe injury and/or frostbite. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control may cause pollution. /Phosphorus pentafluoride; Phosphorus pentafluoride, compressed/

/GUIDE 125: GASES - CORROSIVE/ Fire or Explosion: Some may burn, but none ignite readily. Vapors from liquefied gas are initially heavier than air and spread along ground. Some of these materials may react violently with water. Cylinders exposed to fire may vent and release toxic and/or corrosive gas through pressure relief devices. Containers may explode when heated. Ruptured cylinders may rocket. /Phosphorus pentafluoride; Phosphorus pentafluoride, compressed/

/GUIDE 125: GASES - CORROSIVE/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area for at least 100 meters (330 feet) in all directions. Keep unauthorized personnel away. Stay upwind. Many gases are heavier than air and will spread along ground and collect in low or confined areas (sewers, basements, tanks). Keep out of low areas. Ventilate closed spaces before entering. /Phosphorus pentafluoride; Phosphorus pentafluoride, compressed/

For more DOT Emergency Guidelines (Complete) data for PHOSPHORUS PENTAFLUORIDE (9 total), please visit the HSDB record page.

IMO 2.3; Phosphorus pentafluoride

UN 2198; Phosphorus pentafluoride

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Poison Gas Corrosive