Hydrogen Peroxide

H271: May cause fire or explosion; strong Oxidizer [Danger Oxidizing liquids; Oxidizing solids]

H302: Harmful if swallowed [Warning Acute toxicity, oral]

H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

H332: Harmful if inhaled [Warning Acute toxicity, inhalation]

P210, P220, P260, P261, P264, P270, P271, P280, P283, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P306+P360, P316, P317, P321, P330, P363, P370+P378, P371+P380+P375, P405, P420, and P501 (click each P-code to see the statement)

This chemical does not meet GHS hazard criteria for 0.1% (2 of 1964) of reports.

H271 (90.4%): May cause fire or explosion; strong Oxidizer [Danger Oxidizing liquids; Oxidizing solids]

H302 (97.8%): Harmful if swallowed [Warning Acute toxicity, oral]

H314 (99.6%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

H318 (36.9%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

H332 (93.9%): Harmful if inhaled [Warning Acute toxicity, inhalation]

H335 (27.2%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

H412 (18.5%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P210, P220, P260, P261, P264, P264+P265, P270, P271, P273, P280, P283, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P306+P360, P316, P317, P319, P321, P330, P363, P370+P378, P371+P380+P375, P403+P233, P405, P420, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 1964 reports by companies from 84 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria per 2 of 1964 reports by companies.

There are 83 notifications provided by 1962 of 1964 reports by companies with hazard statement code(s).

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]

H351: Suspected of causing cancer [Warning Carcinogenicity]

H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]

H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]

P203, P210, P220, P260, P264, P264+P265, P270, P280, P283, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P306+P360, P308+P316, P316, P317, P318, P319, P321, P330, P363, P370+P378, P371+P380+P375, P405, P420, and P501 (click each P-code to see the statement)

H311: Toxic in contact with skin [Danger Acute toxicity, dermal]

H330: Fatal if inhaled [Danger Acute toxicity, inhalation]

H331: Toxic if inhaled [Danger Acute toxicity, inhalation]

H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

P203, P210, P220, P260, P261, P262, P264, P264+P265, P270, P271, P273, P280, P283, P284, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P306+P360, P308+P316, P316, P317, P318, P319, P320, P321, P330, P361+P364, P363, P370+P378, P371+P380+P375, P391, P403+P233, P405, P420, and P501 (click each P-code to see the statement)

H313: May be harmful in contact with skin [Warning Acute toxicity, dermal]

H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

P203, P210, P220, P260, P261, P264, P264+P265, P270, P271, P280, P283, P301+P317, P301+P330+P331, P302+P317, P302+P361+P354, P304+P340, P305+P354+P338, P306+P360, P308+P316, P316, P317, P318, P319, P321, P330, P363, P370+P378, P371+P380+P375, P403+P233, P405, P420, and P501 (click each P-code to see the statement)

H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P210, P220, P260, P261, P264, P270, P271, P280, P283, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P306+P360, P316, P317, P319, P321, P330, P363, P370+P378, P371+P380+P375, P403+P233, P405, P420, and P501 (click each P-code to see the statement)

H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]

H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P260, P261, P264, P264+P265, P271, P273, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P319, P321, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Fresh air, rest. Half-upright position. Refer immediately for medical attention.

First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer immediately for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention.

Excerpt from ERG Guide 143 [Oxidizers (Unstable)]:

Refer to the "General First Aid" section. Specific First Aid: Contaminated clothing may be a fire risk when dry. (ERG, 2024)

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. Corrosive chemicals will destroy the membranes of the mouth, throat, and esophagus and, in addition, have a high risk of being aspirated into the victim's lungs during vomiting which increases the medical problems. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. Transport the victim IMMEDIATELY to a hospital. (NTP, 1992)

Excerpt from ERG Guide 140 [Oxidizers]:

Signs and Symptoms of Acute Hydrogen Peroxide Exposure: Signs and symptoms of acute exposure to hydrogen peroxide may be severe and include irritation or burns to the skin, eyes, respiratory tract, mouth, esophagus, stomach, and intestines. Distension or rupture of the stomach and other hollow viscera may occur; vomiting is common. Corneal ulceration may develop.

Emergency Life-Support Procedures: Acute exposure to hydrogen peroxide may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:

1. Move victims to fresh air. Emergency personnel should avoid self-exposure to hydrogen peroxide.

2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.

3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.

4. Transport to a health care facility.

Dermal/Eye Exposure:

1. Remove victims from exposure. Emergency personnel should avoid self- exposure to hydrogen peroxide.

3. Remove contaminated clothing as soon as possible.

4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.

5. Wash exposed skin areas THOROUGHLY with soap and water.

6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.

7. Transport to a health care facility.

Ingestion Exposure:

1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.

2. DO NOT induce vomiting or attempt to neutralize!

4. Activated charcoal is of no value.

5. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults, 250 mL (8 oz or 1 cup). Water or milk should be given only if victims are conscious and alert.

6. Transport to a health care facility. (EPA, 1998)

General First Aid:

· Call 911 or emergency medical service.

· Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.

· Move victim to fresh air if it can be done safely.

· Administer oxygen if breathing is difficult.

· If victim is not breathing:

-- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.

-- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).

-- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.

Excerpt from ERG Guide 143 [Oxidizers (Unstable)]:

SMALL FIRE: Use water. Do not use dry chemicals or foams. CO2 or Halon® may provide limited control.

LARGE FIRE: Flood fire area with water from a distance. Do not move cargo or vehicle if cargo has been exposed to heat. If it can be done safely, move undamaged containers away from the area around the fire. Do not get water inside containers: a violent reaction may occur.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Cool containers with flooding quantities of water until well after fire is out. Dike runoff from fire control for later disposal. ALWAYS stay away from tanks in direct contact with flames. For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn. (ERG, 2024)

Excerpt from ERG Guide 140 [Oxidizers]:

LARGE FIRE: Flood fire area with water from a distance. Do not move cargo or vehicle if cargo has been exposed to heat. If it can be done safely, move undamaged containers away from the area around the fire.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: For ammonium nitrate products: Do not fight cargo fire. Withdraw, evacuate and isolate area for at least 1600 meters (1 mile). Treat as an explosive (ERG Guide 112). Do not enter area for 24 hours or until expert advice has been provided. Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Cool containers with flooding quantities of water until well after fire is out. ALWAYS stay away from tanks in direct contact with flames. For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn. (ERG, 2024)

Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Wear self-contained (positive pressure if available) breathing apparatus and full protective clothing. Move container from fire area if you can do it without risk. Cool containers that are exposed to flames with water from the side until well after fire is out. For massive fire in cargo area, use unamnned hose holder or monitor nozzles; if this is impossible, withdraw from area and let fire burn.

Not flammable. Fires should be fought with water since the use of chemical extinguishants may accelerate decomposition. Small fires: water only; no dry chemical or carbon dioxide. Large fires: flood fire area with water. (EPA, 1998)

In case of fire in the surroundings, use appropriate extinguishing media. In case of fire: keep drums, etc., cool by spraying with water.

Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. /Hydrogen peroxide solution (>/= 30% to <50%)/

Advice for firefighters: Wear self-contained breathing apparatus for firefighting if necessary. /Hydrogen peroxide solution (>/= 30% to <50%)/

If material involved in fire: Use water in flooding quantities as fog. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. /Hydrogen peroxide, aqueous solutions/

Evacuation: If fire becomes uncontrollable - consider evacuation of one-half (1/2) mile radius. /Hydrogen peroxide, aqueous solutions/

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Keep unauthorized personnel away.

· Stay upwind, uphill and/or upstream.

· Ventilate closed spaces before entering, but only if properly trained and equipped.

· Keep combustibles (wood, paper, oil, etc.) away from spilled material.

· Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.

· Stop leak if you can do it without risk.

· Do not get water inside containers.

Small Dry Spill

· With clean shovel, place material into clean, dry container and cover loosely; move containers from spill area.

Small Liquid Spill

· Use a non-combustible material like vermiculite or sand to soak up the product and place into a container for later disposal.

Large Spill

· Dike far ahead of liquid spill for later disposal.

· Use water spray to reduce vapors or divert vapor cloud drift.

· Prevent entry into waterways, sewers, basements or confined areas.

Small Spill

· Flush area with large amounts of water.

· DO NOT CLEAN-UP OR DISPOSE OF, EXCEPT UNDER SUPERVISION OF A SPECIALIST.

Excerpt from ERG Guide 143 [Oxidizers (Unstable)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Excerpt from ERG Guide 140 [Oxidizers]:

LARGE SPILL: Consider initial downwind evacuation for at least 100 meters (330 feet).

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. If ammonium nitrate products are in a tank, rail car or truck and involved in a fire, ISOLATE for 1600 meters (1 mile) in all directions; also, initiate evacuation including emergency responders for 1600 meters (1 mile) in all directions. (ERG, 2024)

Immediate precautionary measure

· Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

· Consider initial downwind evacuation for at least 100 meters (330 feet).

· If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

· If ammonium nitrate products are in a tank, rail car or truck and involved in a fire, ISOLATE for 1600 meters (1 mile) in all directions; also, initiate evacuation including emergency responders for 1600 meters (1 mile) in all directions.

· For highlighted materials: see Table 1 - Initial Isolation and Protective Action Distances.

· For non-highlighted materials: increase the immediate precautionary measure distance, in the downwind direction, as necessary.

Consult an expert! Personal protection: chemical protection suit including self-contained breathing apparatus. Ventilation. Do NOT let this chemical enter the environment. Absorb liquid in sand or inert absorbent. Do NOT absorb in saw-dust or other combustible absorbents. Carefully collect remainder. Store and dispose of according to local regulations.

ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up: Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. /Hydrogen peroxide solution (>/= 30% to <50%)/

Environmental considerations - land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Dilute slowly with water. Absorb bulk liquid with fly ash or cement powder. /Hydrogen peroxide, aqueous solutions/

/LABORATORY QUANTITIES/ Wear face shield and goggles, laboratory coat, and butyl rubber gloves. Cover spill with a 1:1:1 mixture by weight of sodium carbonate or calcium carbonate, clay cat litter (bentonite), and sand. Dampen with water. Using a soft plastic scoop, transfer the mix into a container. Transport to the fume hood. Slowly add to a pail of cold water. Gradually add to an excess of aqueous sodium metabisulfite solution. Decant the liquid to the drain. Treat the solid as normal refuse.

SRP: Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in air, soil or water; effects on animal, aquatic and plant life; and conformance with environmental and public health regulations. If it is possible or reasonable use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination.

Product: Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Offer surplus and non-recyclable solutions to a licensed disposal company; Contaminated packaging: Dispose of as unused product. /Hydrogen peroxide solution (>/= 30% to <50%)/

Wear butyl rubber gloves, eye protection, and laboratory coat. A body shield should be available. In the fume hood, prepare a dilute solution (5%) of peroxide by cautiously adding to a large volume of water. Gradually, while stirring, add to a 50% excess of aqueous sodium metabisulfite in a round-bottom flask equipped with a thermometer. An increase in temperature indicates that reaction is taking place. Acidify the reaction if it does not proceed spontaneously. Neutralize the reaction mixture and wash it into the drain.

Excerpt from ERG Guide 143 [Oxidizers (Unstable)]:

Keep combustibles (wood, paper, oil, etc.) away from spilled material. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Use water spray to reduce vapors or divert vapor cloud drift. Prevent entry into waterways, sewers, basements or confined areas.

SMALL SPILL: Flush area with large amounts of water.

LARGE SPILL: DO NOT CLEAN-UP OR DISPOSE OF, EXCEPT UNDER SUPERVISION OF A SPECIALIST. (ERG, 2024)

Excerpt from ERG Guide 140 [Oxidizers]:

Keep combustibles (wood, paper, oil, etc.) away from spilled material. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Do not get water inside containers.

SMALL DRY SPILL: With clean shovel, place material into clean, dry container and cover loosely; move containers from spill area.

SMALL LIQUID SPILL: Use a non-combustible material like vermiculite or sand to soak up the product and place into a container for later disposal.

LARGE SPILL: Dike far ahead of liquid spill for later disposal. (ERG, 2024)

Caution : Explosion potential is high. Hydrogen peroxide may ignite combustable materials.

Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Keep combustibles (wood, paper, oil, etc.) away from spilled material. Do not touch spilled material; stop leak if you can do it without risk. Use water spray to reduce vapors; do not get water inside container.

Small dry spills: with clean shovel place material into clean, dry container and cover; move containers from spill area.

Small spills: flush area with flooding amounts of water.

Large spills: dike far ahead of spill for later disposal. (EPA, 1998)

Store in an area without drain or sewer access. Separated from food and feedstuffs. See Chemical Dangers. Cool. Keep in the dark. Store in vented containers. Store only if stabilized.

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Recommended storage temperature 2 - 8 °C. /Hydrogen peroxide solution (>/= 30% to <50%)/

Store in original closed container. Be sure that the container vent is working properly. Do not add any other compound to the container. When empty, flush container thoroughly with clean water.

Keep protected from light and in a cool place.

Hydrogen peroxide topical solution should be stored in tight, light-resistant containers at 15-30 °C. To ensure greater stability, the inside surfaces of containers should be as free as possible from rough points since these promote decomposition.

· Wear positive pressure self-contained breathing apparatus (SCBA).

· Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE.

· Structural firefighters' protective clothing provides thermal protection but only limited chemical protection.

0.5 [ppm]

10 [ppm]

50 [ppm]

100 [ppm]

1 ppm (1.4 mg/m³)

TWA 1 ppm (1.4 mg/m3)

1.0 [ppm]

75 ppm [From NPG: Hydrogen peroxide] (NIOSH, 2024)

75 ppm (NIOSH, 2024)

75.0 [ppm]

Excerpts from Documentation for IDLHs: Other animal data: It has been reported that mice tolerated a single 4­hour exposure to 75 ppm [Svirbely]. \\ Human data: It has been stated that although the short­term exposure tolerance is unknown, it is probably about 75 ppm [AIHA 1957]. Death has resulted in a man who drank 100 ml [Raukhverger and Solodko 1974].

See: 772841

8 hr Time Weighted Avg (TWA): 1 ppm

Peak Exposure Recommendation: Transient increases in workers' exposure levels may exceed 3 times the value of the TLV-TWA level for no more than 15 minutes at a time, on no more than 4 occasions spaced 1 hour apart during a workday, and under no circumstances should they exceed 5 times the value of the TLV-TWA level. In addition, the 8-hour TWA is not to be exceeded for an 8-hour work period.

A3; Confirmed animal carcinogen with unknown relevance to humans.

1 ppm as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans).

1 ppm [1990]

0.71 mg/m

Small Fire

· Use water. Do not use dry chemicals or foams. CO2 or Halon® may provide limited control.

Large Fire

· Flood fire area with water from a distance.

· Do not move cargo or vehicle if cargo has been exposed to heat.

· If it can be done safely, move undamaged containers away from the area around the fire.

Fire Involving Tanks, Rail Tank Cars or Highway Tanks

· For ammonium nitrate products: Do not fight cargo fire. Withdraw, evacuate and isolate area for at least 1600 meters (1 mile). Treat as an explosive (GUIDE 112). Do not enter area for 24 hours or until expert advice has been provided.

· Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.

· Cool containers with flooding quantities of water until well after fire is out.

· ALWAYS stay away from tanks in direct contact with flames.

· For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn.

· Do not get water inside containers: a violent reaction may occur.

· Dike runoff from fire control for later disposal.

ERPG-1: 10 ppm - one hour exposure limit: 1 = mild transient health effects or objectionable odor [AIHA]

ERPG-2: 50 ppm - one hour exposure limit: 2 = impaired ability to take protective action [AIHA]

ERPG-3: 100 ppm - one hour exposure limit: 3 = life threatening health effects [AIHA]

Emergency Response Planning Guidlines (ERPGs) for hydrogen peroxide:[Table#1615]

A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20 °C.

Hydrogen peroxide, aqueous solution, stabilized, with more than 60% hydrogen peroxide appears as a colorless liquid. Vapors may irritate the eyes and mucous membranes. Under prolonged exposure to fire or heat containers may violently rupture due to decomposition. Used to bleach textiles and wood pulp, in chemical manufacturing and food processing.

Hydrogen peroxide, aqueous solution, with not less than 20% but not more than 60% hydrogen peroxide (stabilized as necessary) appears as colorless aqueous solution. Vapors may irritate the eyes and mucous membranes. Contact with most common metals and their compounds may cause violent decomposition, especially in the higher concentrations. Contact with combustible materials may result in spontaneous ignition. Prolonged exposure to fire or heat may cause decomposition and rupturing of the container. Used to bleach textiles and wood pulp, in chemical manufacturing and food processing.

Hydrogen peroxide solution is the colorless liquid dissolved in water. Its vapors are irritating to the eyes and mucous membranes. The material, especially the higher concentrations, can violently decompose in contact with most common metals and their compounds. Contact with combustible materials can result in spontaneous ignition. Under prolonged exposure to fire or heat containers may violently rupture due to decomposition of the material. It is used to bleach textiles and wood pulp, in chemical manufacturing and food processing.

Hydrogen peroxide, stabilized appears as a crystalline solid at low temperatures. Has a slightly pungent, irritating odor. Used in the bleaching and deodorizing of textiles, wood pulp, hair, fur, etc. as a source of organic and inorganic peroxides; pulp and paper industry; plasticizers; rocket fuel; foam rubber; manufacture of glycerol; antichlor; dyeing; electroplating; antiseptic; laboratory reagent; epoxidation; hydroxylation; oxidation and reduction; viscosity control for starch and cellulose derivatives; refining and cleaning metals; bleaching and oxidizing agent in foods; neutralizing agent in wine distillation; seed disinfectant; substitute for chlorine in water and sewage treatment. (EPA, 1998)

CBI; Liquid

Colorless liquid with a slightly sharp odor. [Note: The pure compound is a crystalline solid below 12 degrees F. Often used in an aqueous solution.]; [NIOSH]

COLOURLESS LIQUID.

Colorless liquid with a slightly sharp odor.

Colorless liquid with a slightly sharp odor. [Note: The pure compound is a crystalline solid below 12 °F. Often used in an aqueous solution.]

Colorless liquid

At low temperatures a crystalline solid /90% solution/

Colorless liquid ... [Note: The pure compound is a crystalline solid below 12 degrees F. Often used in an aqueous solution]

... Slightly sharp odor ...

Odorless, or having an odor resembling that of ozone

Slightly acid

302.4 °F at 760 mmHg (NTP, 1992)

306 °F at 760 mmHg ; 258 °F for concentrations greater than 52% (EPA, 1998)

150.2 °C

141 °C (90%)

150.2 °C @760 [mm Hg]

31.3 °F (NTP, 1992)

31 to 40 °F for concentrations greater than 52% (EPA, 1998)

-0.43 °C

-11 °C (90%), -39 °C (70%)

greater than or equal to 100 mg/mL at 72 °F (NTP, 1992)

Miscible (NIOSH, 2024)

Soluble in cold water

In water, 1X10+6 mgL at 25 °C

Very soluble in water

Miscible with water

Soluble in ether; insoluble in petroleum ether. Decomposed into water and oxygen by many organic solvents.

For more Solubility (Complete) data for Hydrogen peroxide (6 total), please visit the HSDB record page.

1000 mg/mL at 25 °C

Solubility in water: miscible

Miscible

1.11 at 68 °F (NTP, 1992) - Denser than water; will sink

1.463 at 32 °F 1.29/1.3 at 68F for concentrations greater than 52% (EPA, 1998) - Denser than water; will sink

1.44 g/cu cm 25 °C

Density, solid: 1.71 g/cc

Contains 2.5-3.5% by wt of H2O2 = 8-12 vols oxygen. Colorless, slightly acid liquid. Density approximately 1.00 /3% solution Hydrogen Peroxide/

An aqueous solution.

An aqueous solution that is readily diluted.

Water soluble.

Oxidizing Agents, Strong

Water and Aqueous Solutions

Explosive

Strong Oxidizing Agent

CSL00009

ACETONE + Hydrogen peroxide

Formation of acetone peroxides possible. Try to avoid combination or check for peroxides

ACS Safety Letters

CSL00021

Acetic anhydride + Hydrogen peroxide

explosion hazard: anhydride could have combined with peracetic acid to form diacetyl peroxide. This organic peroxide is known to be a shock-sensitive explosive

oxidation

CSL00022

Hydrogen peroxide + DMSO

Overpressurization Hazard if heated above 150 degrees C

Gas Under Pressure

CSL00041

Steel Drum + Hydrogen peroxide

Steel drum burst when used for storing peroxide waste

peroxide

User-Reported

CSL00050

Hydrogen peroxide

When using hydrogen peroxide make sure to completely quench all of the unreacted hydrogen peroxide before concentrating the reaction solution (or workup) to avoid an explosion.

Explosive,Oxidizer

CSL00169

Hydrogen peroxide + 2-Chloropyridine

Explosion resulted from uncontrolled addition of hydrogen peroxide

Not Available

User Reported

04/22/2022

04/21/2022

CSL00178

Formic acid + Hydrogen peroxide

Reaction resulted in an explosion

CSL00189

Sulfuric acid + Hydrogen peroxide + Peroxymonosulfuric acid + Water + Piranha solution

Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org

IDENTIFICATION AND USE: Hydrogen peroxide is a colorless liquid. It is an oxidizing agent which, in the presence of organic matter or if permitted to become alkaline, vigorously decomposes to oxygen and water. Hydrogen peroxide is used as a 6% solution for bleaching hair, and some disinfectant solutions for contact lenses contain a 3% hydrogen peroxide. Chlorine-free bleaches contain 6% hydrogen peroxide. Some newer fabric stain removers and bleaches contain 5% to 15% hydrogen peroxide. Industrial strengths of hydrogen peroxide are manufactured up to 90%. They are used mainly as bleaching and oxidizing agents. Solutions of 90% are used as rocket fuel. HUMAN STUDIES: The dissociation of hydrogen peroxide is a violent and exothermic reaction. Ingestion results in gastrointestinal irritation, the severity of which depends on the concentration of the solution. There is also a risk for a gas embolism. A number of deaths have been reported in the literature. In most cases the exposures were to concentrated solutions of 30% to 40%. Other reactions include vomiting (the vomitus may be frothy due to the liberation of oxygen), hematemesis, burning of the throat, and gastric distension due to the release of oxygen. Lethargy, coma, convulsions, shock and respiratory arrest have also been reported. Gastrointestinal bleeding and burns to the stomach and duodenum may occur. In severe cases ischemic ECG changes and EMD (electromechanical dissociation) may be observed because of embolization of the heart restricting blood flow. Hydrogen peroxide is an irritant to the skin with paraesthesia, blistering and whitening; solutions >10% may cause burns. Hydrogen peroxide is irritating to the eyes with a burning sensation, conjunctival hyperemia, lacrimation, and severe pain which resolves within a few hours. There are rare cases of temporary corneal injury resulting from the application of 3% solution to the eye on contact lenses including punctuate staining of the cornea, decreased vision, corneal opacity and edema. Cerebral infarction resulting from gas embolization of the cerebral vasculature has been reported in an 84-year-old man. Multiple brain embolisms occurred in a 63-year-old who ingested hydrogen peroxide. DNA strand breaks and chromosomal aberrations were studied in human cells treated with hydrogen peroxide. DNA strand breaks could be produced at dose levels of hydrogen peroxide much lower than those which induced chromosomal aberrations. ANIMAL STUDIES: After ip injection of 0.5 mL of 5% hydrogen peroxide into adult mice, a radiation-like effect was observed; pyknotic nuclei were induced in the intestine and thymus within 2 hr and persisted for up to 24 hr. In rabbits and cats that died after iv administration of hydrogen peroxide, the lungs were found to be pale and emphysematous, with considerable amounts of gas in the great veins and in the right side of the heart. Application of a drop of 10 to 30% to rabbit's eye caused superficial corneal haze, and, if there were defects in the epithelium, could cause localized swelling and opacities in the corneal stroma. Also, 5% solution caused superficial corneal haze and much conjunctival reaction, but these effects were gone in 24 hr. Hydrogen peroxide was mutagenic to Salmonella typhimurium TA92 and TA102 and was positive in a forward mutation test in Salmonella typhimurium SV50. Single strand scissions were produced in T7 DNA upon incubation with hydrogen peroxide in aqueous solution at neutral pH. ECOTOXICITY STUDIES: Hydrogen peroxide was not teratogenic in Xenopus developing embryos.

Evaluation: There is inadequate evidence in humans for the carcinogenicity of hydrogen peroxide. There is limited evidence in experimental animals for the carcinogenicity of hydrogen peroxide. Overall evaluation: Hydrogen peroxide is not classifiable as to its carcinogenicity to humans (Group 3).

A3. Confirmed animal carcinogen with unknown relevance to humans.

Hydrogen peroxide

Group 3: Not classifiable as to its carcinogenicity to humans

Volume 36: (1985) Allyl Compounds, Aldehydes, Epoxides and Peroxides

Volume Sup 7: Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1 to 42, 1987; 440 pages; ISBN 92-832-1411-0 (out of print)

Volume 71: (1999) Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide (Part 1, Part 2, Part 3)

The substance can be absorbed into the body by inhalation of its vapour, by ingestion and through the skin.

inhalation, ingestion, skin and/or eye contact

Sore throat. Cough. Dizziness. Headache. Nausea. Shortness of breath.

MAY BE ABSORBED! Skin discoloration. Swelling. Redness. Pain. Skin burns.

Redness. Pain. Blurred vision. Corneal damage. Burns.

Aspiration hazard! Sore throat. Abdominal pain. Abdominal distension. Shock or collapse.

irritation eyes, nose, throat; corneal ulcer; erythema (skin redness), vesiculation skin; bleaching hair

Eyes, skin, respiratory system

Dermatotoxin - Skin burns.

Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.

ACGIH Carcinogen - Confirmed Animal.

LC50 (rat) = 2,000 mg/m3/4 hr

LD50 Rabbit iv 15 g/kg

LD50 Rat dermal 4060 mg/kg

To explore the cardiac effects of iron with or without hydrogen peroxide, the isolated perfused rat heart and enzymatically isolated ventricular cardiomyocyte were used. It was shown that treatment with cell-permeable iron (Fe-HQ) for 10 min reduced the contractile amplitude and velocity and end diastolic cell length in the cardiomyocyte and increased the contents of lactate dehydrogenase (LDH) and creatine kinase (CK) in the coronary effluent and malondialdehyde (MDA) in the myocardium. The left ventricular developed pressure (LVDP), +/-dP/dtmax, and heart rate and coronary flow showed a biphasic phase, an increase at first followed by a decline. Treatment with hydrogen peroxide for 10 min following Fe-HQ augmented the effect of iron with an increase in coronary LDH and CK release and myocardial MDA content, and decrease in LVDP, +/-dP/dtmax and heart rate. Perfusion of reduced glutathione with hydrogen peroxide counteracted these effects of Fe-HQ and hydrogen peroxide while dimethyl sulfoxide had no effect on the injury induced by Fe-HQ and hydrogen peroxide in the isolated rat heart. This suggests that augmentation of myocardial injury as a result of an increase in intracellular iron by hydrogen peroxide might involve the dysfunction of sulfydryl group containing proteins but not the hydroxyl radicals.

It has been shown that the mucolytic agent erdosteine (N-carboxymethylthio-acetyl-homocysteine thiolactone) has anti-inflammatory and anti-oxidant properties, and an active metabolite I (MET I) containing pharmacologically active sulphydryl group has been found to have a free radical scavenging activity. The aim of this study was to assess the ability of erdosteine metabolite I to protect A549 human lung adenocarcinoma cell against hydrogen peroxide (H2O2)-mediated oxidative stress and oxidative DNA damage. When A549 cells were pre-treated with the active metabolite I (2.5-5-10 ug/mL) for 10-30 min and then exposed to H2O2 (1-4 mM) for two additional hours at 37 degrees C, 5% at CO2, the intracellular peroxide production, reflected by dichlorofluorescein (DCF) fluorescence, decreased in a concentration-dependent manner. Furthermore, using a comet assay as an indicator for oxidative DNA damage, it was found that the metabolite I prevented damage to cells exposed to short-term H2O2 treatment. The data suggest that this compound is effective in preventing H2O2-induced oxidative stress and DNA damage in A549 cells. The underlying mechanisms involve the scavenging of intracellular reactive oxygen species (ROS).

Oxidative stress reduces cell viability and contributes to disease processes. Flavonoids including anthocyanins and proanthocyanidins reportedly induce intracellular antioxidant defense systems. Thus, in this study, we examined the antioxidant effects of a commercial extract from black soybean seed coats (BE), which are rich in anthocyanin and proanthocyanidin, and investigated the associated intracellular mechanisms in HepG2 cells. HepG2 cells treated with hydrogen peroxide (HPO) showed 60% viability, whereas pretreatment with BE-containing media for 2 hr ameliorated HPO-mediated cell death by up to 90%. Pretreatment with BE for 2 hr partially blocked HPO-mediated activation of extracellular-signal-regulated kinase (ERK) in HepG2 cells, and that for 1 hr led to a 20% increase in intracellular total protein phosphatase (PP) activity, which is known to deactivate protein kinases. These results indicate that BE prevents HPO-mediated cell damage by inhibiting ERK signaling, potentially via PPs.

Hydrogen peroxide (HP) or cyanide (CN) are bacteriostatic at low-millimolar concentrations for growing Escherichia coli, whereas CN+HP mixture is strongly bactericidal. We show that this synergistic toxicity is associated with ... chromosomal fragmentation. Since CN alone does not kill at any concentration, while HP alone kills at 20 mM, CN must potentiate HP poisoning. The CN+HP killing is blocked by iron chelators, suggesting Fenton's reaction. Indeed, we show that CN enhances plasmid DNA relaxation due to Fenton's reaction in vitro. However, mutants with elevated iron or HP pools are not acutely sensitive to HP-alone treatment, suggesting that, in addition, in vivo CN recruits iron from intracellular depots. We found that part of the CN-recruited iron pool is managed by ferritin and Dps: ferritin releases iron on cue from CN, while Dps sequesters it, quelling Fenton's reaction. We propose that disrupting intracellular iron trafficking is a common strategy employed by the immune system to kill microbes.

For more Interactions (Complete) data for Hydrogen peroxide (9 total), please visit the HSDB record page.

Immediate first aid: Ensure adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Oxidizers/

Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Do not attempt to neutralize because of exothermic reaction. Cover skin burns with dry, sterile dressings after decontamination ... . /Oxidizers/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Early intubation, at the first sign of upper airway obstruction, may be necessary. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload. ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Oxidizers/

/SIGNS AND SYMPTOMS/ Potential symptoms of overexposure are irritation of eyes, nose and throat; corneal ulceration; erythema, vesicles on skin; bleaching of hair.

/SIGNS AND SYMPTOMS/ Pure hydrogen peroxide, its solutions, vapors, and mists are very irritating to body tissue. This irritation can vary from mild to severe depending upon the concentration of hydrogen peroxide. For instance, solutions of hydrogen peroxide of 35 wt% and over can easily cause blistering of the skin. ... The eyes are particularly sensitive to this material.

/SIGNS AND SYMPTOMS/ Large doses presumably produce gastritis and esophagitis. Cases of rupture of the colon, proctitis and ulcerative colitis have been reported following hydrogen peroxide enemas.

/SIGNS AND SYMPTOMS/ Workers exposed to vapors from 90% hydrogen peroxide have noted primarily respiratory irritation, but splash of such high concentration is generally feared as a potential cause of severe corneal damage.

For more Human Toxicity Excerpts (Complete) data for Hydrogen peroxide (33 total), please visit the HSDB record page.

/LABORATORY ANIMALS: Acute Exposure/ There is so far no generally accepted animal model of chronic cystitis by which potential therapies can be evaluated. In this study, we aimed to establish a new mouse model of cystitis based on the proinflammatory effects of reactive oxygen species. A single intravesical injection of 1.5% hydrogen peroxide (H2O2) significantly increased the numbers of voids by 1 day after injection in female mice, which lasted up to 7 days. The H2O2 injection rapidly increased the bladder weight by 3 hr in parallel with the histological damage and hyperpermeability of urothelial barrier. Although the urothelial dysfunction was recovered to normal by 7 days, increase in bladder weight, edematous thickening of the submucosa, and vascular hyperpermeability were apparent even 7 days after injection. During the time course, massive infiltration of neutrophils and increased expression of inflammatory cytokines were observed in the bladder. An intraperitoneal administration of oxybutynin, amitriptyline, indomethacin, or morphine attenuated the H2O2-induced frequent urination. These findings suggest that an intravesical injection of H2O2 induces relatively long-lasting inflammatory and overactive bladder, compared with existing cystitis models. The intravesical H2O2 injection model may be a simple and useful tool in the pathological study and drug discovery for chronic cystitis.

/LABORATORY ANIMALS: Acute Exposure/ Some clinicians use hydrogen peroxide (H2O2) to clear the lumen of ventilation tubes that become blocked postoperatively. The ototoxicity associated with H2O2 has been controversial. We designed an experiment to test if H2O2 damages the cochlear hair cells using a Chinchilla laniger animal model. Nine chinchillas (18 ears) were included in this study. Each animal was used as its own control. Following the insertion of ventilation tubes in both ears and baseline recordings of the auditory brain stem responses (ABR), we instilled 2 mL of 3 percent H2O2 into their right external auditory canals (experimental ears). H2O2 was left in the external auditory canal for a total of 5 minutes and then was drained. We instilled a normal saline control solution in their left ears (control ears) in a similar fashion. ABR recordings were performed 1 day after the last instillation of H2O2 and 5 days later. There was no statistically significant difference in the ABR thresholds of the experimental and control ears. H2O2 did not appear to cause ototoxicity in chinchilla ears with tympanostomy tubes exposed to H2O2 instillation using a standard clinical protocol.

/LABORATORY ANIMALS: Acute Exposure/ We previously established a long-lasting cystitis model by an intravesical injection of hydrogen peroxide (H2O2) into mice. In this study, we assessed the pain-related behaviors in the cystitis model. An intravesical injection of 1.5% H2O2 transiently decreased spontaneous locomotor activity at 3 hr after injection, indicative of acute spontaneous pain. In contrast, licking response to a bladder distention was slowly observed as licks to the lower abdomen at 7 and 14 days after injection, which was attenuated by amitriptyline and morphine, but not by oxybutynin. These results suggest that H2O2-induced chronic cystitis model shows delayed and long-lasting painful pathological condition.

/LABORATORY ANIMALS: Acute Exposure/ After ip injection of 0.5 mL of 5% hydrogen peroxide into adult mice, a radiation like effect was observed; pyknotic nuclei were induced in the intestine and thymus within 2 hr and persisted for up to 24 hr.

LD50; Species: Anas platyrhynchos (Mallard Duck) age 16 wk; oral via capsule 1049 mg/kg (95% confidence interval: 830-1332 mg/kg) /35% purity/

LC50; Species: Anas platyrhynchos (Mallard Duck) age 5 days; dietary >5000 ppm for 8 days /35% purity/

LC50; Species: Colinus virginianus (Northern Bobwhite Quail) age 11 days; dietary >5000 ppm for 8 days /35% purity/

The substance is toxic to aquatic organisms.

Gaseous hydrogen peroxide is a key component and product of the earth's lower atmospheric photochemical reactions, in both clean and polluted atmospheres. Atmospheric hydrogen peroxide is believed to be generated exclusively by gas-phase photochemical reactions. It has been found in rain and surface water, in human and plant tissues, in foods and beverages and in bacteria(1). Hydrogen peroxide occurs in cloud water with higher values generally occurring in the vicinity of lightning activity(2).

TERRESTRIAL FATE: Hydrogen peroxide is unstable and breaks down rapidly to oxygen and water(1). Therefore, adsorption to soil, volatilization and biodegradation are not important environmental fate processes in soil(SRC).

AQUATIC FATE: Hydrogen peroxide is unstable and breaks down rapidly to oxygen and water(1). Therefore, adsorption to suspended solids and sediment, volatilization, biodegradation and bioconcentration are not important environmental fate processes in water(SRC).

ATMOSPHERIC FATE: Hydrogen peroxide is unstable and breaks down rapidly to oxygen and water. It is expected to be broken down by sunlight(1).

Measurements of hydrogen peroxide concentrations in the gas-phase and in cloud water were obtained in the vicinity of the USA Carolinas coast between late Jan and early Mar 1986. Gas phase concentrations, determined by a fluorometric method, were always less than 2.4 ppb and generally less than 1 ppb. Vertical profiles of hydrogen peroxide in the clear air around clouds and storm systems were highly variable. Concentrations of hydrogen peroxide in cloud water ranged from the detection limit of 0.3 uM to 112 uM, with higher values generally occurring in the vicinity of lightning activity. Hydrogen peroxide concentrations in cloud water were well below those calculated to be in Henry's law equilibrium with gas-phase concentrations of hydrogen peroxide in the cloudy air.

According to the 2016 TSCA Inventory Update Reporting data, 20 reporting facilities estimate the number of persons reasonably likely to be exposed during the manufacturing, processing, or use of hydrogen peroxide in the United States may be as low as 10 workers to less than 10,000 but unknown or unreasonably ascertainable as to how many workers per plant; the data may be greatly underestimated due to confidential business information (CBI) or unknown values(1).

NIOSH (NOES Survey 1981-1983) has statistically estimated that 1,006,752 workers (727,702 of these are female) are potentially exposed to 90% solution hydrogen peroxide in the US(1). Occupational exposure to hydrogen peroxide may occur through inhalation and dermal contact with this compound at workplaces where hydrogen peroxide is produced or used(SRC). The general population is expected to be exposed to hydroperoxide through the use of consumer products containing this compound(SRC).

SRP: Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in air, soil or water; effects on animal, aquatic and plant life; and conformance with environmental and public health regulations. If it is possible or reasonable use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination.

Product: Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Offer surplus and non-recyclable solutions to a licensed disposal company; Contaminated packaging: Dispose of as unused product. /Hydrogen peroxide solution (>/= 30% to <50%)/

Wear butyl rubber gloves, eye protection, and laboratory coat. A body shield should be available. In the fume hood, prepare a dilute solution (5%) of peroxide by cautiously adding to a large volume of water. Gradually, while stirring, add to a 50% excess of aqueous sodium metabisulfite in a round-bottom flask equipped with a thermometer. An increase in temperature indicates that reaction is taking place. Acidify the reaction if it does not proceed spontaneously. Neutralize the reaction mixture and wash it into the drain.

Dilute and drain with abundant water. Recommended method: Discharge to sewer. Recommendable method: Discharge to sewer. Not recommendable methods: Evaporation & oxidation. Peer-review: Extreme caution - potentially explosive. Strong oxidizing agent. Handle in new glass or polished clean aluminum. Avoid inhalation. Highly unstable material. (Peer-review conclusions of an IRPTC expert consultation (May 1985))

SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.

/GUIDE 140 OXIDIZERS/ Fire or Explosion: These substances will accelerate burning when involved in a fire. Some may decompose explosively when heated or involved in a fire. May explode from heat or contamination. Some will react explosively with hydrocarbons (fuels). May ignite combustibles (wood, paper, oil, clothing, etc.). Containers may explode when heated. Runoff may create fire or explosion hazard. /Hydrogen peroxide, aqueous solution, with not less than 20% but not more than 60% Hydrogen peroxide (stabilized as necessary); Hydrogen peroxide, aqueous solution, with not less than 8% but less than 20% Hydrogen peroxide/

/GUIDE 140 OXIDIZERS/ Health: Inhalation, ingestion or contact (skin, eyes) with vapors or substance may cause severe injury, burns or death. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may cause pollution. /Hydrogen peroxide, aqueous solution, with not less than 20% but not more than 60% Hydrogen peroxide (stabilized as necessary); Hydrogen peroxide, aqueous solution, with not less than 8% but less than 20% Hydrogen peroxide/

/GUIDE 140 OXIDIZERS/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind, uphill and/or upstream. Ventilate closed spaces before entering. /Hydrogen peroxide, aqueous solution, with not less than 20% but not more than 60% Hydrogen peroxide (stabilized as necessary); Hydrogen peroxide, aqueous solution, with not less than 8% but less than 20% Hydrogen peroxide/

/GUIDE 140 OXIDIZERS/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing will only provide limited protection. /Hydrogen peroxide, aqueous solution, with not less than 20% but not more than 60% Hydrogen peroxide (stabilized as necessary); Hydrogen peroxide, aqueous solution, with not less than 8% but less than 20% Hydrogen peroxide/

For more DOT Emergency Guidelines (Complete) data for Hydrogen peroxide (16 total), please visit the HSDB record page.

2984 140(8-20% solution)

2014 140(20-60% solution)

2015 143(>60% solution)

UN 2014; Hydrogen, peroxide, aqueous solutions with more than 40 percent but not more than 60 percent hydrogen peroxide (stabilized as necessary); Hydrogen peroxide, aqueous solutions with not less than 20 percent but not more than 40 percent hydrogen peroxide (stabilized as necessary)

UN 2015; Hydrogen peroxide, stabilized or Hydrogen peroxide aqueous solutions, stabilized with more than 60 percent hydrogen peroxide

UN 2984; Hydrogen, peroxide, aqueous solutions with not less than 8 percent but less than 20 percent hydrogen peroxide (stabilized as necessary)

IMO 5.1; Hydrogen peroxide, aqueous solution with not less than 20% but not more than 60% hydrogen peroxide (stabilized as necessary); Hydrogen peroxide, stabilized or hydrogen peroxide, aqueous solution, stabilized with more than 60% hydrogen peroxide; Hydrogen peroxide, aqueous solution with not less than 8% but less than 20% hydrogen peroxide (stabilized as necessary)

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials. Hydrogen peroxide, aqueous solution with 20% or more but 40% or less hydrogen peroxide (stabilized as necessary); Hydrogen peroxide with more than 40% but 60% or less hydrogen peroxide (stabilized as necessary); Hydrogen peroxide, aqueous solution, stabilized with more than 60% hydrogen peroxide; Hydrogen peroxide, stabilized; Hydrogen peroxide, aqueous solution with 8% or more but less than 20% hydrogen peroxide (stabilized as necessary) are included on the dangerous goods list. /Hydrogen peroxide, aqueous solution with 20% or more but 40% or less hydrogen peroxide (stabilized as necessary); Hydrogen peroxide with more than 40% but 60% or less hydrogen peroxide (stabilized as necessary); Hydrogen peroxide, aqueous solution, stabilized with more than 60% hydrogen peroxide; Hydrogen peroxide, stabilized; Hydrogen peroxide, aqueous solution with 8% or more but less than 20% hydrogen peroxide (stabilized as necessary)/

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article. Hydrogen peroxide, aqueous solution with not less than 20% but not more than 60% hydrogen peroxide (stabilized as necessary); Hydrogen peroxide stabilized or hydrogen peroxide, aqueous solution, stabilized with more than 60% hydrogen peroxide; Hydrogen peroxide, aqueous solution, with not less than 8% but less than 20% hydrogen peroxide (stabilized as necessary) are included on the dangerous goods list. /Hydrogen peroxide, aqueous solution with not less than 20% but not more than 60% hydrogen peroxide (stabilized as necessary); Hydrogen peroxide stabilized or hydrogen peroxide, aqueous solution, stabilized with more than 60% hydrogen peroxide; Hydrogen peroxide, aqueous solution, with not less than 8% but less than 20% hydrogen peroxide (stabilized as necessary)/

Oxidizer Corrosive

Oxidizer

Special material.

UN Hazard Class: 5.1; UN Subsidiary Risks: 8; UN Pack Group: I