Calcium Dihydrogen Phosphate

This chemical does not meet GHS hazard criteria for 0.7% (3 of 414) of reports.

H318 (90.1%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

P264+P265, P280, P305+P354+P338, and P317 (click each P-code to see the statement)

Aggregated GHS information provided per 414 reports by companies from 7 notifications to the ECHA C&L Inventory.

Reported as not meeting GHS hazard criteria per 3 of 414 reports by companies.

There are 6 notifications provided by 411 of 414 reports by companies with hazard statement code(s).

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Residues of calcium phosphate are exempted from the requirement of a tolerance when used as a solid diluent or carrier in accordance with good agricultural practices as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops or to raw agricultural commodities after harvest. /Calcium phosphate/

Large Crystals; Dry Powder

Granular powder or white, deliquescent crystals or granules

Solid; Deliquescent when impure; Mostly soluble in water; [Merck Index] Fine white crystals; [MSDSonline]

SHINING TRICLINIC PLATES, CRYSTALLINE POWDER OR GRANULES

COLORLESS, PEARLY SCALES OR POWDER

Strong acid taste

Solubility: Cold water 1.8 g/100 cc @ 30 °C; decomposes in hot water. /Calcium phosphate monobasic monohydrate/

SOL IN DIL HYDROCHLORIC ACID; MODERATELY SOL IN WATER; SOL IN NITRIC ACID OR ACETIC ACID

2.220 @ 18 °C/4 °C

Index of refraction: 1.5292, 1.5176, 1.4392. /Calcium phospate monobasic monohydrate/

NON-HYGROSCOPIC WHEN PURE

LOSES WATER @ 100 °C

DECOMP @ 200 °C

Decomposes at 203 °C. /Calcium phosphate monobasic monohydrate/

Metals -> Phosphates, Metallic Salts

Cosmetic ingredients (Calcium Dihydrogen Phosphate) -> CIR (Cosmetic Ingredient Review)

Buffering; Oral care; Bulking; Viscosity controlling; Antiplaque; Abrasive

DOUGH STRENGTHENER, FIRMING AGENT, FLOUR TREATING AGENT, LEAVENING AGENT, MALTING OR FERMENTING AID, NUTRIENT SUPPLEMENT, PH CONTROL AGENT, SEQUESTRANT, STABILIZER OR THICKENER -> FDA Substance added to food

FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR

Plastics -> Pigments agents

Plastics -> N.a.

The CIR Expert Panel concluded that the following 31 ingredients are safe in the present practices of use and concentration in cosmetics as described in this safety assessment, when formulated to be non-irritating...Calcium Dihydrogen Phosphate...

Safe for use in cosmetics, with qualifications

FAO/WHO EXPERT COMMITTEE ON FOOD ADDITIVES...RECOMMENDED.../LEVELS/ FOR TOTAL DIETARY PHOSPHORUS...UNCONDITIONAL ACCEPTANCE LEVEL /OF LESS THAN 30 MG/KG BODY WT/ IS CONSIDERED SAFE IN ANY TYPE OF DIET...CONDITIONAL ACCEPTANCE LEVEL /OF 30-70 MG/KG BODY WT/ IS ACCEPTABLE ONLY WHEN DIETARY CALCIUM LEVEL IS HIGH /PHOSPHATES/

Monocalcium phosphate

8 mg/kg-day

PDF Document

Inadequate information to assess carcinogenic potential

PPRTV Archive

PPRTV Current

... OCULAR IRRITATION & CORNEAL BURNS CAUSED BY CONTACT WITH FERTILIZERS WERE ATTRIBUTABLE ...TO FREE PHOSPHORIC ACID OR PHOSPHORIC ACID LIBERATED FROM SUPERPHOSPHATE ... PARTICLES OF CALCIUM SUPERPHOSPHATE CHARACTERISTICALLY APPEARED TO CAUSE LOCALIZED BLUISH-WHITE CORNEAL OPACITIES WHICH EVENTUALLY CLEARED.

... NOT IRRITATING & TOXIC DOSES BY INGESTION WOULD HAVE TO BE IN EXCESS OF 2 G/KG. ... SKIN SENSITIZATION IS UNUSUAL. ASPIRATION OR INHALATION ... COULD CAUSE CHEM PNEUMONITIS. IMPLANTATION ... WILL CAUSE FOREIGN BODY REACTION. /CALCIUM PHOSPHATE/

QUANTATIVE CHANGES IN SEVERAL SERUM COMPONENTS & INCR URINARY EXCRETION OF PHOSPHATES & FLUORIDE IONS OCCURRED AFTER INGESTION OF 18% CALCIUM SUPERPHOSPHATE IN SHEEP & 30% CALCIUM HYPERPHOSPHATE IN CALF. TEMPORARY DIARRHEA & WT LOSS ALSO OCCURRED IN SHEEP.

IN RATS INHIBITION OF CALCIUM 2+ ABSORPTION WAS FUNCTION OF PHOSPHATE DOSE UNTIL A VALUE WAS REACHED ABOVE WHICH NO ADDITIONAL INHIBITORY EFFECT WAS OBSERVED.

THE EFFECTIVE /DIETARY/ LEVELS OF PHOSPHATES ARE USUALLY 0.5% OR LESS. WHEN THIS LEVEL ... WAS CONSUMED IN DIETS OF MANY ANIMALS, IT WAS SHOWN TO BE NONTOXIC. /PHOSPHATES/

... ANIMAL-FEEDING STUDIES ... INDICATE THAT LEVELS OF 0.5% ... PHOSPHATE COULD BE TOLERATED IN DIET WITHOUT ADVERSE PHYSIOLOGICAL EFFECTS. HIGHER LEVELS COULD ... BE TOLERATED IF PROPER ... BALANCE OF ... IONS ... CALCIUM, MAGNESIUM & POTASSIUM, IS MAINTAINED. /PHOSPHATES/

Occupational exposure involves acetyl cellulose makers, bronze alloy makers, munitions workers, smoke bomb and incendiary makers, pesticide rat poison worker, fertilizer makers, electroluminescent-coating makers, and semiconductor workers. /Phosphorus/

Occupational exposure involves acetyl cellulose makers, bronze alloy makers, munitions workers, smoke bomb and incendiary makers, pesticide rat poison worker, fertilizer makers, electroluminescent-coating makers, and semiconductor workers. /Phosphorus/