Mercuric Iodide

H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral]

H310 (100%): Fatal in contact with skin [Danger Acute toxicity, dermal]

H330 (100%): Fatal if inhaled [Danger Acute toxicity, inhalation]

H373 (100%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P260, P262, P264, P270, P271, P273, P280, P284, P301+P316, P302+P352, P304+P340, P316, P319, P320, P321, P330, P361+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 82 reports by companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

H300: Fatal if swallowed [Danger Acute toxicity, oral]

H310: Fatal in contact with skin [Danger Acute toxicity, dermal]

H315: Causes skin irritation [Warning Skin corrosion/irritation]

H317: May cause an allergic skin reaction [Warning Sensitization, Skin]

H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P261, P262, P264, P264+P265, P270, P272, P280, P301+P316, P302+P352, P305+P351+P338, P316, P321, P330, P332+P317, P333+P317, P337+P317, P361+P364, P362+P364, P405, and P501 (click each P-code to see the statement)

If material involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty). Use water in flooding quantities as fog. Use foam, dry chemical or carbon dioxide. /Mercuric iodide; mercuric iodide, solution/

Mercury spills should be cleaned up immediately by use of a special vacuum cleaner. Then the area should be washed with a dilute calcium sulfide solution. Small quantities of mercury can be picked up by mixing with copper metal granules. ... /Mercury/

Mercury removal from waste water can be accomplished by these processes: BMS process; Chlorine is added to the waste water, oxidizing any mercury present to the ionic state. The BMS adsorbent (an activated carbon concentrate of sulfur cmpd on its surface) is used to collect ionic mercury. The spent adsorbent is then distilled to recover the mercury, leaving a carbon residue for reuse or disposal. TMR IMAC Process; Waste water is fed into a reactor, whereby a slight excess of chlorine is maintained, oxidizing any mercury present to ionic mercury. The liquid is then passed through the TMR IMAC ion-exchange resin where mercury ions are adsorbed. The mercury is then stripped from the spent resin with hydrochloric acid solution. /Mercury cmpds/

SPILLED MERCURY CMPD OR SOLN CAN BE CLEANED UP BY ANY METHOD THAT DOES NOT CAUSE EXCESSIVE AIRBORNE CONTAMINATION OR SKIN CONTACT. /MERCURY COMPOUNDS/

1) Ventilate area of spill. 2) Collect spilled material for reclamation using commercially available mercury vapor depressants or specialized vacuum cleaners. /Inorganic mercury/

Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number D009, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.

Personnel protection: Avoid breathing dusts, and fumes from burning material. Keep upwind. Avoid bodily contact with the material. ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water. ... If contact with the material anticipated, wear appropriate chemical protective clothing. /Mercuric iodide; mercuric iodide solution/

If material not involved in fire: Keep material out of water sources and sewers. /Mercuric iodide; mercuric iodide solution/

Preventative measure: adequate ventilation; careful attention to good housekeeping, e.g., avoidance of spills, and prompt and proper cleaning if a spill occurs; all containers of mercury and its compounds should be kept tightly closed; should be washed on a regular basis with dilute calcium sulfide solution or other suitable reactant; floors should be nonporous; all workers directly involved in the plant operation should shower thoroughly each day before leaving. /Mercury compounds/

PROTECT FROM LIGHT.

Storage temperature: Ambient

0.02 [mg/m3], as Hg, inhalable fraction[German Research Foundation (DFG)]

0.0091 [ppm]

0.25 [ppm]

0.50 [ppm]

0.1 [mg/m3], as Hg

10.0 [mg/m3], as Hg

10 mg/cu m (as Hg) /Mercury cmpd (except (organo) alkyl compounds (as Hg)/

0.02 [mg/m3], as Hg (0.01 ppm, inhalable fraction and vapor (iodides))

8 hr Time Weighted Avg (TWA): 0.025 mg/cu m, skin /Mercury, elemental and inorganic forms, as Hg/

Excursion Limit Recommendation: Excursions in worker exposure levels may exceed 3 times the TLV-TWA for no more than a total of 30 minutes during a work day, and under no circumstances should they exceed 5 times the TLV-TWA, provided that the TLV-TWA is not exceeded. /Mercury, elemental and inorganic forms, as Hg/

A4: Not classifiable as a human carcinogen. /Mercury, elemental and inorganic forms, as Hg/

Biological Exposure Index (BEI): Determinant: total inorganic mercury in urine; Sampling Time: prior to shift; BEI:35 ug/g creatine. The determinant may be present in biological specimens collected from subjects who have not been occupationally exposed, at a concentration which could affect interpretation of the result. Such background concentrations are incorporated in the BEI value. /Mercury/

Biological Exposure Index (BEI): Determinant: total inorganic mercury in blood; Sampling Time: end of shift at end of workweek; BEI: 15 ug/L. The determinant may be present in biological specimens collected from subjects who have not been occupationally exposed, at a concentration which could affect interpretation of the result. Such background concentrations are incorporated in the BEI value. /Mercury/

Chronic Inhalation: 0.0002 mg/m3 (L134)

Use /SRP: NISOH certified respirator/, goggles, or face shield and protective gloves.

Light-sensitive red solid; turns yellow at 130 deg C; [Merck Index]

Scarlet-red, heavy, powder

Red or yellow form

Red tetrahedral crystal or powder

Odorless

Almost tasteless

350 °C @760 [mm Hg]

0.006 g/100 g water @ 25 °C

1 g/115 ml alcohol; 1 g/20 ml boiling alcohol; 1 g/120 ml ether; 1 g/60 ml acetone; 1 g/910 ml chloroform; 1 g/75 ml ethyl acetate; 1 g/260 ml carbon disulfide; 1 g/230 ml olive oil; 1 g/50 ml castor oil

1 g dissolves readily in alkali iodides, mercuric chloride, Na2S2O3

Soluble in boiling water and in solutions of sodium thiosulfate or potassium iodide or other hot alkali chloride solutions; almost completely insoluble in water.

6.28 no temp

100 mm Hg at 261.8 °C; 400 mm Hg at 324.2 °C

100 [mm Hg] @261.8 °C

SENSITIVE TO LIGHT

INDICES OF REFRACTION: 2.455 (EPSILON); 2.748 (OMEGA)

Sublimes @ 350 °C; @ 130 °C becomes yellow, then red on cooling

Transition point: 127 °C

Heat of fusion: 9.9 cal/g

Decomposes in ammonium hydroxide

Soluble ionized mercuric salts give a yellow precipitate of HgO with NaOH and a red precipitate of HgI2 with alkali iodide.

phonon wavenumber

dielectric constant

pseudobinary system

crystal structure

Debye frequency

dielectricity

diffusion

enthalpy

effective mass

isothermal section

Gibbs energy

Wyckoff sequence

phase equilibrium

positional coordinate

temperature-composition section

electron conductivity

space group

phase diagram

unit cell parameter

COMBINATION OF CHLORINE TRIFLUORIDE & HGI2 ... RESULTS IN A REACTION WITH FLAME.

A mixture of sodium and mercuric iodide or a mixture of potassium and mercuric iodide produces strong explosion on impact.

High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through alterations in intracellular thiol status, mercury can promote oxidative stress, lipid peroxidation, mitochondrial dysfunction, and changes in heme metabolism. Mercury is known to bind to microsomal and mitochondrial enzymes, resulting in cell injury and death. For example, mercury is known to inhibit aquaporins, halting water flow across the cell membrane. It also inhibits the protein LCK, which causes decreased T-cell signalling and immune system depression. Mercury is also believed to inhibit neuronal excitability by acting on the postsynaptic neuronal membrane. It also affects the nervous system by inhibiting protein kinase C and alkaline phosphatase, which impairs brain microvascular formation and function, as well as alters the blood-brain barrier. Mercury also produces an autoimmune response, likely by modification of major histocompatibility complex (MHC) class II molecules, self peptides, T-cell receptors, or cell-surface adhesion molecules. (L7, A8, A25, A26)

A4: Not classifiable as a human carcinogen. /Mercury, elemental and inorganic forms, as Hg/

3, not classifiable as to its carcinogenicity to humans. (L135)

Mercury mainly affects the nervous system. Exposure to high levels of metallic, inorganic, or organic mercury can permanently damage the brain, kidneys, and developing fetus. Effects on brain functioning may result in irritability, shyness, tremors, changes in vision or hearing, and memory problems. Acrodynia, a type of mercury poisoning in children, is characterized by pain and pink discoloration of the hands and feet. Mercury poisoning can also cause Hunter-Russell syndrome and Minamata disease. (L7)

Oral (L7) ; inhalation (L7); dermal (L7)

Common symptoms include peripheral neuropathy (presenting as paresthesia or itching, burning or pain), skin discoloration (pink cheeks, fingertips and toes), edema (swelling), and desquamation (dead skin peels off in layers). (A5)

Neurotoxin - Sensorimotor

Nephrotoxin - The chemical is potentially toxic to the kidneys in the occupational setting.

ACGIH Carcinogen - Not Classifiable.

LD50: 18 mg/kg (Oral, Rat) (L439)

LD50: 4.2 mg/kg (Intraperitoneal, Rat) (L439)

Mercury poisoning is treated by immediate decontamination and chelation therapy using DMSA, DMPS, DPCN, or dimercaprol. (A7)

A 31 year old inhabitant of French Guiana was prescribed mercuric iodide per os for a half month. Shortly before the end of the treatment he developed fasciculations in the trunk and particularly the lower limb muscles, distal painful paresthesias with vasomotor disorders, episodes of excessive perspiration and palmoplantar erythema, moderate fluctuating hypertension, progressive loss of weight and irritability with insomnia. Clinical and electrical signs of neuropathy were lacking. The clinical picture was that of Morvan's fibrillary chorea with acrodynia, the conditions of onset strongly suggesting a mercurial intoxication. Blood and particularly urine mercury levels were elevated. Administration of dimercaprol considerably increased urinary excretion of mercury and there was progressive improvement and finally recovery after two months of dimercaprol treatment.

MERCURIC IODIDE INJECTED INTO ANTERIOR CHAMBER OF RABBITS HAS CAUSED PURULENT EXUDATION AND INFLAMMATION.

DOGS & CATS ARE PARTICULARLY SUSCEPTIBLE TO TOXIC EFFECTS OF HG FROM MERCURIAL OINTMENTS, BOTH DUE TO DIRECT ABSORPTION & LICKING OF PARTS TO WHICH OINTMENT HAS BEEN APPLIED. POISONING IN CATTLE HAS ALSO BEEN RECORDED AFTER USE OF OINTMENTS CONTAINING ... MERCURIC IODIDE ...

Mercuric iodide (HgI2), mercuric chloride (HgCl2) ... were administered via stomach to males and females (1-20 days of pregnancy) to study the toxic effects on the male gonads and embryogenesis, respectively. In the second series, mercury (Hg) salts were given to male rats daily for 2 mo. All the cmpd were markedly embryotoxic and the severity depended on the dose and the intake schedule. ... HgI2 was more toxic than HgCl2. These materials characteristically decr the size of the placenta. They showed no teratogenic activity. The embryolethal effect of HgI2 (1/8 LD50) was most pronounced when it was administered during 1-4 days of pregnancy. The embryo deaths were not practically any different from the control if HgI2 was administered on other days. Thus, these Hg cmpd are sufficiently effective with reference to intrauterine development (cause embryo death but show no teratogenicity), whereas the embryolethal effect is most evident during the initial stage of embryogenesis.

Among mercuric iodide, mercuric chloride, and mercuric ammonium chloride, the acute toxic concn to monolayer cell cultures (Hepl-2, Vero and amnion) was the lowest for mercuric iodide (HgI2) (cell degeneration), followed by that of mercuric chloride (HgCl2). The Hg(II) compounds belonged to class II type materials (highly toxic). The sensitivity of the cell lines to the Hg was practically similar; only human amnion cells were somewhat more sensitive than the remaining ones. The Hg inhibited the cell growth and multiplication and the max effect was observed by 48 hr. The investigated cmpd inhibited monoamine oxidase activity in the hepatic mitochondria at 10-2M.

For more Non-Human Toxicity Excerpts (Complete) data for MERCURIC IODIDE (6 total), please visit the HSDB record page.

LC50 Plumaria elegans (red alga, sporiing) 156 ug/l 18 hr /Conditions of bioassay not specified/

LC50 Plumaria elegans (red alga, sporiing) 156 ug/l 18 hr /Conditions of bioassay not specified/

Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number D009, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.

/GUIDE 151: SUBSTANCES - TOXIC (NON-COMBUSTIBLE)/ Health: Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

/GUIDE 151: SUBSTANCES - TOXIC (NON-COMBUSTIBLE)/ Fire or Explosion: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Containers may explode when heated. Runoff may pollute waterways.

/GUIDE 151: SUBSTANCES - TOXIC (NON-COMBUSTIBLE)/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at lease 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas.

/GUIDE 151: SUBSTANCES - TOXIC (NON-COMBUSTIBLE)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.

For more DOT Emergency Guidelines (Complete) data for MERCURIC IODIDE (8 total), please visit the HSDB record page.

UN 1638; Mercuric iodide (solid/solution)

IMO 6.1; Mercury iodide, solid/solution

49 232 62; Mercuric iodide, solid

49 232 49; Mercuric iodide, solution

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.