Calcium hydride

H260: In contact with water releases flammable gases which may ignite spontaneously [Danger Substances and mixtures which in contact with water, emit flammable gases]

P223, P231+P232, P280, P302+P335+P334, P370+P378, P402+P404, and P501 (click each P-code to see the statement)

H260 (100%): In contact with water releases flammable gases which may ignite spontaneously [Danger Substances and mixtures which in contact with water, emit flammable gases]

Aggregated GHS information provided per 249 reports by companies from 3 notifications to the ECHA C&L Inventory.

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Excerpt from ERG Guide 138 [Substances - Water-Reactive (Emitting Flammable Gases)]:

Refer to the "General First Aid" section. Specific First Aid: In case of contact with substance, wipe from skin immediately; flush skin or eyes with running water for at least 20 minutes. (ERG, 2024)

General First Aid:

· Call 911 or emergency medical service.

· Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.

· Move victim to fresh air if it can be done safely.

· Administer oxygen if breathing is difficult.

· If victim is not breathing:

-- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.

-- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).

-- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.

· Remove and isolate contaminated clothing and shoes.

· For minor skin contact, avoid spreading material on unaffected skin.

· In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.

· For severe burns, immediate medical attention is required.

· Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed.

· Keep victim calm and warm.

· Keep victim under observation.

· For further assistance, contact your local Poison Control Center.

· Note: Basic Life Support (BLS) and Advanced Life Support (ALS) should be done by trained professionals.

Specific First Aid:

· In case of contact with substance, wipe from skin immediately; flush skin or eyes with running water for at least 20 minutes.

In Canada, an Emergency Response Assistance Plan (ERAP) may be required for this product. Please consult the shipping paper and/or the "ERAP" section.

Excerpt from ERG Guide 138 [Substances - Water-Reactive (Emitting Flammable Gases)]:

DO NOT USE WATER OR FOAM.

SMALL FIRE: Dry chemical, soda ash, lime or sand.

LARGE FIRE: DRY sand, dry chemical, soda ash or lime or withdraw from area and let fire burn. If it can be done safely, move undamaged containers away from the area around the fire.

FIRE INVOLVING METALS OR POWDERS (ALUMINUM, LITHIUM, MAGNESIUM, ETC.): Use dry chemical, DRY sand, sodium chloride powder, graphite powder or class D extinguishers; in addition, for Lithium you may use Lith-X® powder or copper powder. Also, see ERG Guide 170.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. (ERG, 2024)

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Keep unauthorized personnel away.

· Stay upwind, uphill and/or upstream.

· Ventilate closed spaces before entering, but only if properly trained and equipped.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

· Do not touch or walk through spilled material.

· Stop leak if you can do it without risk.

· Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material.

· DO NOT GET WATER on spilled substance or inside containers.

Small Spill

· Cover with DRY earth, DRY sand or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain.

· Dike for later disposal; do not apply water unless directed to do so.

Powder Spill

· Cover powder spill with plastic sheet or tarp to minimize spreading and keep powder dry.

· DO NOT CLEAN-UP OR DISPOSE OF, EXCEPT UNDER SUPERVISION OF A SPECIALIST.

Excerpt from ERG Guide 138 [Substances - Water-Reactive (Emitting Flammable Gases)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

LARGE SPILL: Consider initial downwind evacuation for at least 300 meters (1000 feet).

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Immediate precautionary measure

· Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

Large Spill

· Consider initial downwind evacuation for at least 300 meters (1000 feet).

· If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal and plant life; and conformance with environmental and public health regulations.

SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.

SRP: The scientific literature for the use of contact lenses by industrial workers is inconsistent. The benefits or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. The completeness of the cleaning procedures should be considered before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at the end of shift, but should remain at employee's place of work for cleaning.

If the chemical got onto the clothed portion of the body, remove the contaminated clothes as quickly as possible, protecting your own hands and body. Place the victim under a deluge shower. If the chemical got on the victim's exposed skin, such as the hands: Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. If irritation persists, seek medical attention. Wash contaminated clothing before reusing.

Excerpt from ERG Guide 138 [Substances - Water-Reactive (Emitting Flammable Gases)]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material. DO NOT GET WATER on spilled substance or inside containers.

SMALL SPILL: Cover with DRY earth, DRY sand or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain. Dike for later disposal; do not apply water unless directed to do so.

POWDER SPILL: Cover powder spill with plastic sheet or tarp to minimize spreading and keep powder dry. DO NOT CLEAN-UP OR DISPOSE OF, EXCEPT UNDER SUPERVISION OF A SPECIALIST. (ERG, 2024)

· Wear positive pressure self-contained breathing apparatus (SCBA).

· Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE.

· Structural firefighters' protective clothing provides thermal protection but only limited chemical protection.

12 [mg/m3]

130 [mg/m3]

790 [mg/m3]

· DO NOT USE WATER OR FOAM.

Small Fire

· Dry chemical, soda ash, lime or sand.

Large Fire

· DRY sand, dry chemical, soda ash or lime or withdraw from area and let fire burn.

· If it can be done safely, move undamaged containers away from the area around the fire.

Fire Involving Metals or Powders (Aluminum, Lithium, Magnesium, etc.)

· Use dry chemical, DRY sand, sodium chloride powder, graphite powder or class D extinguishers; in addition, for Lithium you may use Lith-X® powder or copper powder. Also, see GUIDE 170.

Fire Involving Tanks, Rail Tank Cars or Highway Tanks

· Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.

· Do not get water inside containers.

· Cool containers with flooding quantities of water until well after fire is out.

· Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.

· ALWAYS stay away from tanks in direct contact with flames.

Excerpt from ERG Guide 138 [Substances - Water-Reactive (Emitting Flammable Gases)]:

Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE. Structural firefighters' protective clothing provides thermal protection but only limited chemical protection. (ERG, 2024)

Splash goggles. Lab coat. Vapor and dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.

Grayish-colored lump or crystalline solid. Irritating to skin and eyes. Used to make other chemicals.

Solid; Commercial product is grey; [Merck Index] Greyish solid; [CAMEO] Light grey odorless powder; [Alfa Aesar MSDS]

Gray orthorhombic crystals or powder

Grayish-white lumps or crystals

Pure calcium hydride crystalizes in the form of colorless, hexagonal prisms... Industrial product contains some calcium metal and is consequently grey

Insoluble in all common inert solvents

1.7 g/cu cm

1.7 @25 °C

Highly ionic

Dissociates into calcium and hydrogen at 990 °C without melting

Decomposes at 675 °C

Decomposes with water, lower alcohols and carboxylic acids to form hydrogen; moderately powerful condensing agent with ketones and acid esters; more powerful reducing agent toward metal oxides than lithium or sodium hydrides

Reacts with water, ethanol

For more Other Experimental Properties (Complete) data for Calcium hydride (7 total), please visit the HSDB record page.

Metals -> Metal Hydrides

Flammable agents - 3rd degree

Reactive agents - 2nd degree

Ignites in air or reacts violently, sometimes explosively, with air of high humidity [Bretherick 1979 p. 107]. Reacts exothermically with water to generate flammable hydrogen gas and calcium hydroxide, a base. [Merck, 11th ed. 1989].

Metal Hydrides, Metal Alkyls, Metal Aryls, and Silanes

Strong Reducing Agent

Water-Reactive

Air-Reactive

When silver fluoride is ground with CALCIUM HYDRIDE the mass becomes incandescent [Mellor 3:389 1946-47]. Heating the hydride strongly with chlorine, bromine, or iodine leads to incandescence. Mixtures of the hydride with various bromates, i.e. barium bromate; chlorates, i.e. barium chlorate, and perchlorates, i.e. potassium perchlorate; explode on grinding, [Mellor, 1946, vol. 3, 651]. CaH2 reacts incandescently with AgF if subject to friction. (Mellor, 1941, Vol. 3, 389, 651).

Extremely reactive or incompatible with moisture. The product reacts violently with water to emit flammable but non toxic gases.

Dermatotoxin - Skin burns.

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Corrosives/

Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Corrosives/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Early intubation, at the first sign of upper airway obstruction, may be necessary. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload .... . Treat seizures with diazepam or lorazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Corrosives/

/LABORATORY ANIMALS: Neurotoxicity/ This study explored the effect of coral calcium hydride (CCH) on rat intrahippocampal antioxidant ability by measuring the /3-methoxycarbonyl-2,2,5,5-tetramethylpyrrolidine-1-oxyl/ (PCAM) nitroxide radical decay ratio when CCH was (a) co-perfused into the hippocampus and (b) fed orally to the rats for 4 weeks under a freely moving state. Estimation of the in vivo antioxidant effect was obtained by administration of the blood-brain barrier-permeable PCAM nitroxide radical and the measured PCAM radical decay ratio then correlated to the amount of antioxidant in the brain using electron spin resonance (ESR) spectroscopy combined with microdialysis. The half-life periods of PCAM in rats treated with CCH in both the co-perfusion and orally fed groups were significantly shorter compared to the control group. These results clarify the mechanism that CCH may exert antioxidant activity by significantly enhancing the basal endogenous antioxidant ability in the hippocampus through a synergistic effect with alpha-tocopherol and ascorbic acid.

/ALTERNATIVE and IN VITRO TESTS/ Recent studies strongly support the hypothesis that an antioxidant diet inhibits the pathologic aging process as shown in senescence-accelerated mouse prone 8 (SAM/P-8). In our previous study in coral calcium hydride (CCH), we reported that a diet rich in antioxidants inhibited the pathologic aging process, increased the endogenous antioxidant ability, and contributed to prolonging the lifespan of SAM/P-8. To test the hypothesis that antioxidant CCH supplementation to SAM/P-8 mice would change the gene expression and to understand how CCH reverses the acceleration of aging in SAM/P-8 mice, /researchers/ used a DNA array to compare the expression levels in the hippocampus of the brains from 16-week-old SAM/P-8 mice that were either treated or not treated with CCH. The most significant up-regulated changes in the gene network of SAM/P-8 mice were free radical scavenging and molecular transport, whereas genes associated with cell death, cancer, and cell cycle were down-regulated. Findings regarding the changes in these messenger RNA might be associated with the inhibition of the acceleration of aging, as observed in SAM/P-8 mice fed a CCH diet.

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal and plant life; and conformance with environmental and public health regulations.

SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.

UN 1404; Calcium hydride

IMO 4.3; Calcium hydride

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Dangerous When Wet