1,2-dibromopropane

H226 (91.8%): Flammable liquid and vapor [Warning Flammable liquids]

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (12.2%): Causes skin irritation [Warning Skin corrosion/irritation]

H319 (12.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H332 (89.8%): Harmful if inhaled [Warning Acute toxicity, inhalation]

H411 (12.2%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P317, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P391, P403+P235, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 49 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

This material is considered to be non-flammable. (NTP, 1992)

If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Use alcohol foam, dry chemical or carbon dioxide. Keep run-off water out of sewers and water sources. /Bromopropanes/

Excerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

LARGE SPILL: Consider initial downwind evacuation for at least 300 meters (1000 feet).

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Use alcohol foam, dry chemical or carbon dioxide. Keep run-off water out of sewers and water sources. /Bromopropanes/

Personnel protection: Avoid breathing vapors. Keep upwind. Do not handle broken packages unless wearing appropriate personal protective equipment. If contact with the material anticipated, wear appropriate chemical protective clothing. /Bromopropanes/

SMALL SPILLS AND LEAKAGE: If you should spill this chemical, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with acetone followed by washing with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

STORAGE PRECAUTIONS: You should store this material in a refrigerator. (NTP, 1992)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter.

RECOMMENDED GLOVE MATERIALS: Permeation data indicate that butyl rubber gloves may provide protection to contact with this compound. Butyl rubber over latex gloves is recommended. However, if this chemical makes direct contact with your gloves, or if a tear, hole or puncture develops, remove them at once. (NTP, 1992)

Personnel Protection: ... Wear appropriate chemical protective gloves, boots and goggles. /Bromopropanes/

1,2-dibromopropane is a colorless liquid. (NTP, 1992)

Colorless liquid; [Merck Index]

Colorless liquid

284 to 288 °F at 760 mmHg (NTP, 1992)

141.9 °C

-67.4 °F (NTP, 1992)

-55.49 °C

Flash point: <-75 °C

In water, 1.43X10+3 mg/L at 25 °C

Soluble in ethanol, ether, and chloroform; slightly soluble in carbon tetrachloride.

1.94 at 68 °F (NTP, 1992) - Denser than water; will sink

1.9324 g/cu cm at 20 °C

7 (NTP, 1992) - Heavier than air; will sink (Relative to Air)

7.84 [mmHg]

7.84 mm Hg at 25 °C

When heated to decomposition it emits toxic fumes of /hydrogen bromide/.

1.623 cP at 20 °C

42.43 kJ/mol at 25 °C

34.14 dyne/cm at 20 °C

Index of refraction = 1.5203 at 20 °C/D

Other Classes -> Halogenated Aliphatics, Saturated

Insoluble in water.

Halogenated Organic Compounds

Halogenated aliphatic compounds, such as 1,2-DIBROMOPROPANE, are moderately or very reactive. Halogenated organics generally become less reactive as more of their hydrogen atoms are replaced with halogen atoms. Materials in this group may be incompatible with strong oxidizing and reducing agents. Also, they may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides. This compound is considered nonflammable. (NTP, 1992)

Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and produce tissue damage. In additon, the formation of hydrobromic and bromic acids will result in secondary irritation. The bromide ion is also known to affect the central nervous system, causing bromism. This is believed to be a result of bromide ions substituting for chloride ions in the in actions of neurotransmitters and transport systems, thus affecting numerous synaptic processes. (L626, L627, A543)

No indication of carcinogenicity to humans (not listed by IARC).

Bromine vapour causes irritation and direct damage to the mucous membranes. Elemental bromine also burns the skin. The bromide ion is a central nervous system depressant and chronic exposure produces neuronal effects. This is called bromism and can result in central reactions reaching from somnolence to coma, cachexia, exicosis, loss of reflexes or pathologic reflexes, clonic seizures, tremor, ataxia, loss of neural sensitivity, paresis, papillar edema of the eyes, abnormal speech, cerebral edema, delirium, aggressiveness, and psychoses. (L625, L626, L627)

Oral (L626) ; inhalation (L626) ; dermal (L626)

Bromine vapour causes irritation and direct damage to the mucous membranes. Symptoms include lacrimation, rhinorrhoea, eye irritation with mucous secretions from the oropharyngeal and upper airways, coughing, dyspnoea, choking, wheezing, epistaxis, and headache. The bromide ion is a central nervous system depressant producing ataxia, slurred speech, tremor, nausea, vomiting, lethargy, dizziness, visual disturbances, unsteadiness, headaches, impaired memory and concentration, disorientation and hallucinations. This is called bromism. (L626, L627)

Neurotoxin - Acute solvent syndrome

Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

LC50 (rat) = 12,000 mg/m3/4h

LD50: 741 mg/kg (Oral, Rat) (T14)

LD50: 75 mg/kg (Intraperitoneal, Mouse) (T14)

LC50: 12 g/m3 over 4 hours (Inhalation, Rat) (263)

LD50 Rat oral 741 mg/kg

LC50 Rat inhalation 12 g/cu m/4hr

LD50 Mouse oral 676 mg/kg

LD50 Mouse ip 75 mg/kg

EYES: irrigate opened eyes for several minutes under running water.

INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice.

SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention.

INHALATION: supply fresh air. If required provide artificial respiration.

/LABORATORY ANIMALS: Acute Exposure/ The acute toxic effects of 2-bromopropane (2-BP) and its analog, 1,2-dibromopropane (1,2-DBP), were investigated in female BALB/c mice. The mice were treated orally with either 2-BP at 2000 and 4000 mg/kg or 1,2-DBP at 300 and 600 mg/kg. Four days before necropsy, the mice were immunized intraperitoneally with sheep red blood cells (SRBCs). 1,2-DBP reduced the weights of the spleen and thymus and decreased the number of splenic cells. In addition, treatment with 1,2-DBP suppressed the antibody response to SRBCs. The time course effects of 2-BP and 1,2-DBP on the hepatotoxic parameters were compared in female BALB/c mice. When mice were treated orally with either one of these chemicals for 6, 12, 24 and 48 h, the activities of serum alanine aminotransferase and aspartate aminotransferase elevated significantly only with 1,2-DBP 24 h after the treatment. The hepatic content of glutathione was reduced by 1,2-DBP.

/GENOTOXICITY/ Dominant lethal studies were conducted in SD male rats with 5 halogenated 3-carbon compounds that are structurally similar to a known mutagen 1,2-dibromo-3-chloropropane (DBCP). ... The estimated dominant lethal mutation index of a group treated with 1,2-dibromopropane was marginal at week 1 of testing.

/GENOTOXICITY/ Seventeen chemicals (solvents, insecticides and intermediates in the production of textiles and resins) were tested in a short-term in vitro system with human lymphocytes to determine their toxic action. The parameters studied were the tritiated thymidine uptake and cell viability in cultures grown with or without a rat liver metabolizing system (S-9 mix). Data obtained showed that dibromopropane toxic effects; ... 1,2-dichlorobenzene maintained in some degree toxicity even in the presence of the S-9 mix.

/GENOTOXICITY/ series of experiments was conducted to determine the mutagenicity and genotoxicity 1,2-dibromopropane. ... Genotoxicity was measured via the SOS chromotest in Escherichia-coli, DNA repair assay of Fisher-334-rat hepatocyte primary culture, His+ reversion induction in Salmonella-typhimurium, the somatic mutation and recombination test (SMART) in Drosophila-melanogaster, and HGPRT locus mutation in ARL-18 rat hepatocyte culture. ... DBP demonstrated genotoxic characteristics in the DNA repair and SMART assays, while genotoxic effects of TBP were indicated in the DNA repair, Salmonella His+ reversion induction, and Salmonella host mediated toxicity assays.

For more Non-Human Toxicity Excerpts (Complete) data for 1,2-DIBROMOPROPANE (6 total), please visit the HSDB record page.

1,2-Diromopropane's production and use as a research chemical may result in its release to the environment through various waste streams. If released to air, a vapor pressure of 7.84 mm Hg at 25 °C indicates 1,2-dibromopropane will exist solely as a vapor in the atmosphere. Vapor-phase 1,2-dibromopropane will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 37 days. 1,2-Dibromopropane does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight. If released to soil, 1,2-dibromopropane is expected to have high mobility based upon an estimated Koc of 80. Volatilization from moist soil surfaces is expected to be an important fate process based upon an estimated Henry's Law constant of 1.46X10-3 atm-cu m/mole. 1,2-Dibromopropane may volatilize from dry soil surfaces based upon its vapor pressure. Biodegradation data are not available for 1,2-dibromopropane. If released into water, 1,2-dibromopropane is not expected to adsorb to suspended solids and sediment based upon the estimated Koc. Volatilization from water surfaces is expected to be an important fate process based upon this compound's estimated Henry's Law constant. Estimated volatilization half-lives for a model river and model lake are 2 hours and 6 days, respectively. An estimated BCF of 10 suggests the potential for bioconcentration in aquatic organisms is low. Using hydrolysis rates measured at elevated temperatures, a hydrolysis half-life of 320 days (rate constant = 2.5X10-8 per second) at 25 °C and pH 7 was calculated for 1,2-dibromopropane. Occupational exposure to 1,2-dibromopropane is expected to be limited to laboratory researchers who use this chemical. (SRC)

1,2-Diromopropane's production and use as a research chemical(1) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 80(SRC), determined from a water solubility of 1.43X10+3 mg/L(2) and a regression-derived equation(3), indicates that 1,2-dibromopropane is expected to have high mobility in soil(SRC). Volatilization of 1,2-dibromopropane from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 1.46X10-3 atm-cu m/mole(SRC), calculated from a vapor pressure of 7.84 mm Hg(4) and water solubility of 1.43X10+3 mg/L(2). 1,2-Dibromopropane is expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(4). Biodegradation data were not available(SRC, 2005).

AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 80(SRC), determined from a water solubility of 1.43X10+3 mg/L(2) and a regression-derived equation(3), indicates that 1,2-dibromopropane is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon an estimated Henry's Law constant of 1.46X10-3 atm-cu m/mole(SRC), calculated from its vapor pressure, 7.84 mm Hg(4), and water solubility, 1.43X10+3 mg/L(3). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 2 hours and 6 days, respectively(SRC). According to a classification scheme(5), an estimated BCF of 10(SRC), from its water solubility(2) and a regression-derived equation(6), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Using hydrolysis rates measured at elevated temperatures, a hydrolysis half-life of 320 days (rate constant = 2.5X10-8 per second) at 25 °C and pH 7 was calculated for 1,2-dibromopropane(7,8). Biodegradation data were not available(SRC, 2005).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 1,2-dibromopropane, which has a vapor pressure of 7.84 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase 1,2-dibromopropane is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 37 days(SRC), calculated from its rate constant of 4.3X10-13 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). 1,2-dibromopropane does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC).

The rate constant for the vapor-phase reaction of 1,2-dibromopropane with photochemically-produced hydroxyl radicals has been estimated as 4.33X10-13 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 37 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). Using hydrolysis rates measured at elevated temperatures, a hydrolysis half-life of 320 days (rate constant = 2.5X10-8 per second) at 25 °C and pH 7 was calculated for 1,2-dibromopropane(2,3). 1,2-Dibromopropane does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC).

An estimated BCF of 10 was calculated for 1,2-dibromopropane(SRC), using a water solubility of 1.43X10+3 mg/L(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

The Koc of 1,2-dibromopropane is estimated as 80(SRC), using a water solubility of 1.43X10+3 mg/L(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 1,2-dibromopropane is expected to have high mobility in soil.

The Henry's Law constant for 1,2-dibromopropane is estimated as 1.46X10-3 atm-cu m/mole(SRC) derived from its vapor pressure, 7.84 mm Hg(1), and water solubility, 1.43X10+3 mg/L(2). This Henry's Law constant indicates that 1,2-dibromopropane is expected to volatilize rapidly from water surfaces(3). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(3) is estimated as 2 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(3) is estimated as 6 days(SRC). 1,2-Dibromopropane's estimated Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). The potential for volatilization of 1,2-dibromopropane from dry soil surfaces may exist(SRC) based upon the vapor pressure(1).

Occupational exposure to 1,2-dibromopropane is expected to be limited to laboratory researchers who use this chemical. (SRC)

1,2-Diromopropane's production and use as a research chemical may result in its release to the environment through various waste streams. If released to air, a vapor pressure of 7.84 mm Hg at 25 °C indicates 1,2-dibromopropane will exist solely as a vapor in the atmosphere. Vapor-phase 1,2-dibromopropane will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 37 days. 1,2-Dibromopropane does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight. If released to soil, 1,2-dibromopropane is expected to have high mobility based upon an estimated Koc of 80. Volatilization from moist soil surfaces is expected to be an important fate process based upon an estimated Henry's Law constant of 1.46X10-3 atm-cu m/mole. 1,2-Dibromopropane may volatilize from dry soil surfaces based upon its vapor pressure. Biodegradation data are not available for 1,2-dibromopropane. If released into water, 1,2-dibromopropane is not expected to adsorb to suspended solids and sediment based upon the estimated Koc. Volatilization from water surfaces is expected to be an important fate process based upon this compound's estimated Henry's Law constant. Estimated volatilization half-lives for a model river and model lake are 2 hours and 6 days, respectively. An estimated BCF of 10 suggests the potential for bioconcentration in aquatic organisms is low. Using hydrolysis rates measured at elevated temperatures, a hydrolysis half-life of 320 days (rate constant = 2.5X10-8 per second) at 25 °C and pH 7 was calculated for 1,2-dibromopropane. Occupational exposure to 1,2-dibromopropane is expected to be limited to laboratory researchers who use this chemical. (SRC)

1,2-Diromopropane's production and use as a research chemical(1) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 80(SRC), determined from a water solubility of 1.43X10+3 mg/L(2) and a regression-derived equation(3), indicates that 1,2-dibromopropane is expected to have high mobility in soil(SRC). Volatilization of 1,2-dibromopropane from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 1.46X10-3 atm-cu m/mole(SRC), calculated from a vapor pressure of 7.84 mm Hg(4) and water solubility of 1.43X10+3 mg/L(2). 1,2-Dibromopropane is expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(4). Biodegradation data were not available(SRC, 2005).

AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 80(SRC), determined from a water solubility of 1.43X10+3 mg/L(2) and a regression-derived equation(3), indicates that 1,2-dibromopropane is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon an estimated Henry's Law constant of 1.46X10-3 atm-cu m/mole(SRC), calculated from its vapor pressure, 7.84 mm Hg(4), and water solubility, 1.43X10+3 mg/L(3). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 2 hours and 6 days, respectively(SRC). According to a classification scheme(5), an estimated BCF of 10(SRC), from its water solubility(2) and a regression-derived equation(6), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Using hydrolysis rates measured at elevated temperatures, a hydrolysis half-life of 320 days (rate constant = 2.5X10-8 per second) at 25 °C and pH 7 was calculated for 1,2-dibromopropane(7,8). Biodegradation data were not available(SRC, 2005).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 1,2-dibromopropane, which has a vapor pressure of 7.84 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase 1,2-dibromopropane is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 37 days(SRC), calculated from its rate constant of 4.3X10-13 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). 1,2-dibromopropane does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC).

The rate constant for the vapor-phase reaction of 1,2-dibromopropane with photochemically-produced hydroxyl radicals has been estimated as 4.33X10-13 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 37 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). Using hydrolysis rates measured at elevated temperatures, a hydrolysis half-life of 320 days (rate constant = 2.5X10-8 per second) at 25 °C and pH 7 was calculated for 1,2-dibromopropane(2,3). 1,2-Dibromopropane does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC).

An estimated BCF of 10 was calculated for 1,2-dibromopropane(SRC), using a water solubility of 1.43X10+3 mg/L(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

The Koc of 1,2-dibromopropane is estimated as 80(SRC), using a water solubility of 1.43X10+3 mg/L(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 1,2-dibromopropane is expected to have high mobility in soil.

The Henry's Law constant for 1,2-dibromopropane is estimated as 1.46X10-3 atm-cu m/mole(SRC) derived from its vapor pressure, 7.84 mm Hg(1), and water solubility, 1.43X10+3 mg/L(2). This Henry's Law constant indicates that 1,2-dibromopropane is expected to volatilize rapidly from water surfaces(3). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(3) is estimated as 2 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(3) is estimated as 6 days(SRC). 1,2-Dibromopropane's estimated Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). The potential for volatilization of 1,2-dibromopropane from dry soil surfaces may exist(SRC) based upon the vapor pressure(1).

Occupational exposure to 1,2-dibromopropane is expected to be limited to laboratory researchers who use this chemical. (SRC)

Combustible Liquid