| Section 1. Identification | |||
|---|---|---|---|
| Chemical Name | 2-Tert-Butylphenol | CAS No. | 88-18-6 |
| Synonyms | 2-tert-butyl phenol;2-(1,1-dimethylethyl)phenol; o-tert-butyl phenol | Chinese Name | 2-叔丁基苯酚 |
| Molecular Formula | C_10H_10O | Molecular Weight | 150.2176 |
| UN No. | 3265 | Data Source | PubChem (NIH/NLM) |
| GHS Hazard Classification | |
|---|---|
| Signal Word | DANGER |
| Pictograms | GHS05 · Corrosive GHS06 · Acute Toxic GHS07 · Irritant GHS08 · Health Hazard GHS09 · Environmental Hazard |
| Hazard Statements | H302H311H312H314H315H318H319H330H332H400H410H411H227H371H401 |
| Precautionary Statements | P260P261P262P264P264+P265P270P271P273P280P284P301+P317P301+P330+P331P302+P352P302+P361+P354P304+P340P305+P351+P338P305+P354+P338P316P317P320P321P330P332+P317P337+P317P361+P364P362+P364P363P391P403+P233P405P501P210P308+P316P370+P378P403 |
| Contents | |||
|---|---|---|---|
| Section 2 | Hazards Identification | Section 4 | First-Aid Measures |
| Section 5 | Fire-Fighting Measures | Section 6 | Accidental Release Measures |
| Section 7 | Handling and Storage | Section 8 | Exposure Controls / Personal Protection |
| Section 9 | Physical and Chemical Properties | Section 11 | Toxicological Information |
| Section 12 | Ecological Information | Section 13 | Disposal Considerations |
| Section 14 | Transport Information | ||
H302 (99.4%): Harmful if swallowed [Warning Acute toxicity, oral]
H311 (75.9%): Toxic in contact with skin [Danger Acute toxicity, dermal]
H312 (18.8%): Harmful in contact with skin [Warning Acute toxicity, dermal]
H314 (43.5%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
H315 (56.5%): Causes skin irritation [Warning Skin corrosion/irritation]
H318 (20.6%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
H319 (56.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H330 (10.2%): Fatal if inhaled [Danger Acute toxicity, inhalation]
H332 (32.5%): Harmful if inhaled [Warning Acute toxicity, inhalation]
H400 (60.9%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
H410 (55.9%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]
H411 (39%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
P260, P261, P262, P264, P264+P265, P270, P271, P273, P280, P284, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P320, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P363, P391, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 798 reports by companies from 16 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]
H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]
H411 (100%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
P260, P261, P264, P270, P271, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P362+P364, P363, P391, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 76 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
H227: Combustible liquid [Warning Flammable liquids]
H302: Harmful if swallowed [Warning Acute toxicity, oral]
H311: Toxic in contact with skin [Danger Acute toxicity, dermal]
H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]
H332: Harmful if inhaled [Warning Acute toxicity, inhalation]
H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure]
H401: Toxic to aquatic life [Hazardous to the aquatic environment, acute hazard]
H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]
P210, P260, P261, P262, P264, P264+P265, P270, P271, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P308+P316, P316, P317, P321, P330, P361+P364, P363, P370+P378, P391, P403, P405, and P501 (click each P-code to see the statement)
Fresh air, rest. Half-upright position. Refer for medical attention.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give one or two glasses of water to drink. Do NOT induce vomiting. Refer for medical attention .
Use powder, carbon dioxide, foam.
If material involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Keep run-off water out of sewers and water sources. /Butyl phenols, liquid/
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable plastic containers. Carefully collect remainder. Then store and dispose of according to local regulations.
SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
If material not on fire and not involved in fire: Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. /Butyl phenols, liquid/
Personnel protection: keep upwind. Avoid breathing vapors. ... Do not handle broken packages unless wearing appropriate personal protective equipment. Avoid bodily contact with the material. /Butyl phenols, liquid/
Separated from strong oxidants, strong bases, acid anhydrides, acid chlorides, metals and food and feedstuffs.
Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying.
The substance is corrosive to the skin and eyes. The vapour is irritating to the respiratory tract. Corrosive on ingestion.
NO open flames. Above 80 °C use a closed system and ventilation.
PREVENT GENERATION OF MISTS! IN ALL CASES CONSULT A DOCTOR!
Use ventilation, local exhaust or breathing protection.
Protective gloves. Protective clothing.
Wear face shield or eye protection in combination with breathing protection.
Do not eat, drink, or smoke during work.
Liquid; Other Solid; Liquid
Light yellow or amber liquid; [HSDB] Colorless or yellow liquid; [MSDSonline]
COLOURLESS-TO-YELLOW LIQUID WITH CHARACTERISTIC ODOUR.
LIGHT YELLOW LIQUID
Amber-colored liquid
223 °C @ 760 mm Hg
230 °F OC
80 °C c.c.
SOL IN ALCOHOL; VERY SOL IN ETHER; SOL IN ALKALI, CARBON TETRACHLORIDE
SOL IN ISOPENTANE, TOLUENE & ETHYL ALCOHOL
INSOL IN WATER
Solubility in water, g/100ml at 20 °C: 0.2 (poor)
0.9783 @ 20 °C/4 °C
Relative density (water = 1): 0.98
Relative vapor density (air = 1): 5.2
0.00015 [mmHg]
1.5X10-4 mm Hg @ 25 °C
Vapor pressure, Pa at 20 °C: 5
log Kow = 3.31
Negative
Agilent XCT
Electrospray ionization
ammonia (10nM)
MeCN (80%)
DOI:10.1021/acs.analchem.7b00595
INDEX OF REFRACTION: 1.5160 @ 20 °C/D
pKa = 10.28
132.9 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID2026525]
13C nuclear magnetic resonance spectrum
Boiling point
Chemical shift
Heat of sublimation
Optical coefficient
Refractive index
Spin-spin coupling constant
Thermal expansion coefficient
Vapor pressure
Other Classes -> Phenols
FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
Fragrance Ingredient (Phenol, 2-(1,1-dimethylethyl)-) -> IFRA transparency List
No indication of carcinogenicity to humans (not listed by IARC).
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.
Cough. Sore throat. Shortness of breath.
Redness. Pain. Burning sensation. Skin burns.
Redness. Pain. Severe deep burns.
Burning sensation in the throat and chest. Abdominal pain. Shock or collapse.
Dermatotoxin - Skin burns.
Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.
LC50 (rat) = 1,070 mg/m3/4h
INHIBITORY EFFECTS OF 18 SYNTHETIC PHENOLIC CMPD, ADDED TO DIET, ON BENZO[A]PYRENE-INDUCED NEOPLASIA OF THE FORESTOMACH OF FEMALE MICE WERE DETERMINED. GROUP OF CMPD WITH WEAKER INHIBITORY ACTION INCLUDED 2-TERT-BUTYLPHENOL.
MODERATE IRRITANT TO EYES & SKIN.
2-TERT-BUTYLPHENOL CAUSED EARLY MELTING OF PHOSPHOLIPID FATTY ACYL CHAINS, BLOCKED CAPACITY OF CYTOCHROME C TO ENHANCE (22) SODIUM PERMEABILITY WHILE HAVING NO EFFECT ON ITS BINDING TO THE VESICLES.
. IN SHRIMP, CRANGON CRANGON, LETHAL THRESHOLD OF 2-TERT-BUTYLPHENOL WAS 2.2 MG/L. O-TERT-BUTYLPHENOL WAS MORE TOXIC THAN M-TERT-BUTYLPHENOL, INDICATING THAT O-SUBSTITUTED ALKYLPHENOLS ARE MORE TOXIC.
The substance is toxic to aquatic organisms.
2-t-Butylphenol's production and use as an intermediate in the manufacture of synthetic resins, plasticizers, surface-active agents, and perfumes or as a starting material for antioxidants and agrochemicals may result in its release to the environment through various waste streams. If released to the atmosphere, 2-t-butylphenol will exist in both the vapor and particulate phases based on an experimental vapor pressure of 1.5X10-4 mm Hg at 25 °C. Vapor-phase 2-t-butylphenol should be degraded in the atmosphere by reaction with photochemically produced hydroxyl radicals with an estimated half-life of about 9.5 hours. Particulate-phase 2-t-butylphenol may be physically removed from the air by wet and dry deposition. 2-t-Butylphenol is expected to have low mobility in soil based on an estimated Koc value of 1500. An estimated Henry's Law constant of 1.4X10-6 suggests that volatilization from moist soil surfaces will be slow. Limited data, mainly derived by analogy to 4-t-butylphenol, indicate that 2-t-butylphenol may be resistant to biodegradation in soil and water environments. 4-t-Butylphenol (at 30 mg/l) was not biodegraded over a 2 week period using an activated sludge inoculum; in river and sea water 11% of the initial concentration of 4-t-butylphenol was biodegraded over 3 days. An estimated BCF value of 190 indicates bioconcentration in aquatic organisms may be an important fate process. This compound was rapidly taken up by zebra fish with a steady state concentration reached within 5 hours; the clearance phase required 6 hours. 2-t-Butylphenol may volatilize from water surfaces given its estimated Henry's Law constant. Estimated volatilization half-lives for a model river and model lake are 31 and 230 days, respectively. Exposure to 2-t-butylphenol may occur occupationally during its production or use in the manufacture of other products. (SRC)
2-t-Butylphenol's production and use as an intermediate in the manufacture of synthetic resins, plasticizers, surface-active agents, and perfumes(1) or as a starting material for antioxidants and agrochemicals(2) may result in its release to the environment through various waste streams(SRC).
TERRESTRIAL FATE: Based on a recommended classification scheme(1), an estimated Koc value of 1500(SRC), determined from an experimental log Kow(2) and a recommended regression-derived equation(3), indicates that 2-t-butylphenol will have low mobility in soil(SRC). Limited data, mainly derived by analogy to 4-t-butylphenol, indicate that 2-t-butylphenol may be resistant to biodegradation(SRC). 4-t-Butylphenol (at 30 mg/L) was not biodegraded over a 2 week period using an activated sludge inoculum(4); in river and sea water 4-t-butylphenol showed 11% biodegradation over 3 days(5). However, resting cells of a Pseudomonas strain obtained by selective enrichment with 4-hydroxybenzoate as the sole carbon source, were able to biodegrade 2-t-butylphenol (oxygen uptake rate 26 nmol O2/min/mg protein)(6). Volatilization of 2-t-butylphenol from moist soil surfaces would be slow(SRC) given an estimated Henry's Law constant of 1.4X10-6 atm-cu m/mole(7,SRC).
AQUATIC FATE: Based on a recommended classification scheme(1), an estimated Koc value of 1500(SRC), determined from an experimental log Kow(2) and a recommended regression-derived equation(3), indicates that 2-t-butylphenol would adsorb to suspended solids and sediment(SRC) in the water. 2-t-Butylphenol would volatilize slowly from water surfaces based on an estimated Henry's Law constant of 1.4X10-6 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). Estimated half-lives for a model river and model lake are 31 and 230 days, respectively(3,SRC). An estimated BCF value of 190(3,SRC), from an experimental log Kow(2), suggests that 2-t-butylphenol may bioconcentrate in aquatic organisms(SRC) according to a recommended classification scheme(5). Limited data, mainly derived by analogy to 4-t-butylphenol, indicate that 2-t-butylphenol may be resistant to biodegradation(SRC). 4-t-Butylphenol (at 30 mg/L) was not biodegraded over a 2 week period using an activated sludge inoculum(6); in river and sea water 4-t-butylphenol showed 11% biodegradation over 3 days(7).
ATMOSPHERIC FATE: According to a suggested classification scheme(1), an experimental vapor pressure of 1.5X10-4 mm Hg at 25 °C(2) indicates that 2-t-butylphenol will exist in both the vapor and particulate phases in the ambient atmosphere(SRC). Vapor-phase 2-t-butylphenol is degraded in the atmosphere by reaction with photochemically produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be about 9.5 hours(3,SRC). Particulate-phase 2-t-butylphenol may be physically removed from the air by wet and dry deposition(SRC).
Resting cells of a Pseudomonas strain obtained by selective enrichment with 4-hydroxybenzoate as the sole carbon source, were able to biodegrade 2-t-butylphenol (oxygen uptake rate 26 nmol O2/min/mg protein)(1). 4-t-Butylphenol (at 30 mg/l) was not biodegraded over a 2 week period using an activated sludge inoculum; in river and sea water 4-t-butylphenol showed 11% biodegradation over 3 days(3). By analogy to 4-t-butylphenol, 2-t-butylphenol may be recalcitrant to biodegradation in the environment(SRC).
The rate constant for the vapor-phase reaction of 2-t-butylphenol with photochemically produced hydroxyl radicals has been estimated as 4.1X10-11 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1,SRC). This corresponds to an atmospheric half-life of about 9.5 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1,SRC). 2-t-Butylphenol has a measured pKa of 10.28(2) indicating that this compound will exist mainly in the non-dissociated form at environmental pH's(SRC).
An estimated BCF value of 190 was calculated for 2-t-butylphenol(SRC), using an experimental log Kow of 3.31(1) and a recommended regression-derived equation(2). According to a recommended classification scheme(3), this BCF value suggests that bioconcentration in aquatic organisms may be an important fate process(SRC). This compound was rapidly taken up by zebra fish with a steady state concentration reached within 5 hours; the clearance phase required 6 hours(3).
The Koc of 2-t-butylphenol is estimated as approximately 1500(SRC), using an experimental log Kow of 3.31(1) and a regression-derived equation(2,SRC). According to a recommended classification scheme(3), this Koc value suggests that 2-t-butylphenol has low mobility in soil(SRC).
The Henry's Law constant for 2-t-butylphenol is estimated as 1.4X10-6 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This value indicates that 2-t-butylphenol will volatilize from water surfaces(2,SRC). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec) is estimated as approximately 31 days(2,SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec) is estimated as approximately 230 days(2,SRC). 2-t-Butylphenol's estimated Henry's Law constant(1,SRC) indicates that volatilization from moist soil may occur(SRC).
SURFACE WATER: 2-t-Butylphenol was detected in Rhine River water at 2 of 6 sites measured in the Rhine River delta, The Netherlands (concentrations of 0.015-0.022 ug/L)(1).
2-t-Butylphenol was reported in the finished water from an advanced wastewater treatment plant at Lake Tahoe, CA at unreported concentrations(1).
NIOSH (NOES Survey 1981-1983) has statistically estimated that 8300 workers (239 of these are female) are potentially exposed to 2-t-butylphenol in the USA(1).
The substance is toxic to aquatic organisms.
2-t-Butylphenol's production and use as an intermediate in the manufacture of synthetic resins, plasticizers, surface-active agents, and perfumes or as a starting material for antioxidants and agrochemicals may result in its release to the environment through various waste streams. If released to the atmosphere, 2-t-butylphenol will exist in both the vapor and particulate phases based on an experimental vapor pressure of 1.5X10-4 mm Hg at 25 °C. Vapor-phase 2-t-butylphenol should be degraded in the atmosphere by reaction with photochemically produced hydroxyl radicals with an estimated half-life of about 9.5 hours. Particulate-phase 2-t-butylphenol may be physically removed from the air by wet and dry deposition. 2-t-Butylphenol is expected to have low mobility in soil based on an estimated Koc value of 1500. An estimated Henry's Law constant of 1.4X10-6 suggests that volatilization from moist soil surfaces will be slow. Limited data, mainly derived by analogy to 4-t-butylphenol, indicate that 2-t-butylphenol may be resistant to biodegradation in soil and water environments. 4-t-Butylphenol (at 30 mg/l) was not biodegraded over a 2 week period using an activated sludge inoculum; in river and sea water 11% of the initial concentration of 4-t-butylphenol was biodegraded over 3 days. An estimated BCF value of 190 indicates bioconcentration in aquatic organisms may be an important fate process. This compound was rapidly taken up by zebra fish with a steady state concentration reached within 5 hours; the clearance phase required 6 hours. 2-t-Butylphenol may volatilize from water surfaces given its estimated Henry's Law constant. Estimated volatilization half-lives for a model river and model lake are 31 and 230 days, respectively. Exposure to 2-t-butylphenol may occur occupationally during its production or use in the manufacture of other products. (SRC)
2-t-Butylphenol's production and use as an intermediate in the manufacture of synthetic resins, plasticizers, surface-active agents, and perfumes(1) or as a starting material for antioxidants and agrochemicals(2) may result in its release to the environment through various waste streams(SRC).
TERRESTRIAL FATE: Based on a recommended classification scheme(1), an estimated Koc value of 1500(SRC), determined from an experimental log Kow(2) and a recommended regression-derived equation(3), indicates that 2-t-butylphenol will have low mobility in soil(SRC). Limited data, mainly derived by analogy to 4-t-butylphenol, indicate that 2-t-butylphenol may be resistant to biodegradation(SRC). 4-t-Butylphenol (at 30 mg/L) was not biodegraded over a 2 week period using an activated sludge inoculum(4); in river and sea water 4-t-butylphenol showed 11% biodegradation over 3 days(5). However, resting cells of a Pseudomonas strain obtained by selective enrichment with 4-hydroxybenzoate as the sole carbon source, were able to biodegrade 2-t-butylphenol (oxygen uptake rate 26 nmol O2/min/mg protein)(6). Volatilization of 2-t-butylphenol from moist soil surfaces would be slow(SRC) given an estimated Henry's Law constant of 1.4X10-6 atm-cu m/mole(7,SRC).
AQUATIC FATE: Based on a recommended classification scheme(1), an estimated Koc value of 1500(SRC), determined from an experimental log Kow(2) and a recommended regression-derived equation(3), indicates that 2-t-butylphenol would adsorb to suspended solids and sediment(SRC) in the water. 2-t-Butylphenol would volatilize slowly from water surfaces based on an estimated Henry's Law constant of 1.4X10-6 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). Estimated half-lives for a model river and model lake are 31 and 230 days, respectively(3,SRC). An estimated BCF value of 190(3,SRC), from an experimental log Kow(2), suggests that 2-t-butylphenol may bioconcentrate in aquatic organisms(SRC) according to a recommended classification scheme(5). Limited data, mainly derived by analogy to 4-t-butylphenol, indicate that 2-t-butylphenol may be resistant to biodegradation(SRC). 4-t-Butylphenol (at 30 mg/L) was not biodegraded over a 2 week period using an activated sludge inoculum(6); in river and sea water 4-t-butylphenol showed 11% biodegradation over 3 days(7).
ATMOSPHERIC FATE: According to a suggested classification scheme(1), an experimental vapor pressure of 1.5X10-4 mm Hg at 25 °C(2) indicates that 2-t-butylphenol will exist in both the vapor and particulate phases in the ambient atmosphere(SRC). Vapor-phase 2-t-butylphenol is degraded in the atmosphere by reaction with photochemically produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be about 9.5 hours(3,SRC). Particulate-phase 2-t-butylphenol may be physically removed from the air by wet and dry deposition(SRC).
Resting cells of a Pseudomonas strain obtained by selective enrichment with 4-hydroxybenzoate as the sole carbon source, were able to biodegrade 2-t-butylphenol (oxygen uptake rate 26 nmol O2/min/mg protein)(1). 4-t-Butylphenol (at 30 mg/l) was not biodegraded over a 2 week period using an activated sludge inoculum; in river and sea water 4-t-butylphenol showed 11% biodegradation over 3 days(3). By analogy to 4-t-butylphenol, 2-t-butylphenol may be recalcitrant to biodegradation in the environment(SRC).
The rate constant for the vapor-phase reaction of 2-t-butylphenol with photochemically produced hydroxyl radicals has been estimated as 4.1X10-11 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1,SRC). This corresponds to an atmospheric half-life of about 9.5 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1,SRC). 2-t-Butylphenol has a measured pKa of 10.28(2) indicating that this compound will exist mainly in the non-dissociated form at environmental pH's(SRC).
An estimated BCF value of 190 was calculated for 2-t-butylphenol(SRC), using an experimental log Kow of 3.31(1) and a recommended regression-derived equation(2). According to a recommended classification scheme(3), this BCF value suggests that bioconcentration in aquatic organisms may be an important fate process(SRC). This compound was rapidly taken up by zebra fish with a steady state concentration reached within 5 hours; the clearance phase required 6 hours(3).
The Koc of 2-t-butylphenol is estimated as approximately 1500(SRC), using an experimental log Kow of 3.31(1) and a regression-derived equation(2,SRC). According to a recommended classification scheme(3), this Koc value suggests that 2-t-butylphenol has low mobility in soil(SRC).
The Henry's Law constant for 2-t-butylphenol is estimated as 1.4X10-6 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This value indicates that 2-t-butylphenol will volatilize from water surfaces(2,SRC). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec) is estimated as approximately 31 days(2,SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec) is estimated as approximately 230 days(2,SRC). 2-t-Butylphenol's estimated Henry's Law constant(1,SRC) indicates that volatilization from moist soil may occur(SRC).
SURFACE WATER: 2-t-Butylphenol was detected in Rhine River water at 2 of 6 sites measured in the Rhine River delta, The Netherlands (concentrations of 0.015-0.022 ug/L)(1).
2-t-Butylphenol was reported in the finished water from an advanced wastewater treatment plant at Lake Tahoe, CA at unreported concentrations(1).
NIOSH (NOES Survey 1981-1983) has statistically estimated that 8300 workers (239 of these are female) are potentially exposed to 2-t-butylphenol in the USA(1).
SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
UN 3145; Alkyl phenols, liquid, NOS
UN 2430; Alkyl phenols, solid, NOS
IMO 8.0; Alkyl phenols, liquid or solid, NOS
No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./
The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.
The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.
Do not transport with food and feedstuffs. Marine pollutant.
UN Hazard Class: 8; UN Pack Group: III