2,4-dinitroaniline

H300: Fatal if swallowed [Danger Acute toxicity, oral]

H310: Fatal in contact with skin [Danger Acute toxicity, dermal]

H330: Fatal if inhaled [Danger Acute toxicity, inhalation]

H373 **: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P260, P262, P264, P270, P271, P273, P280, P284, P301+P316, P302+P352, P304+P340, P316, P319, P320, P321, P330, P361+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral]

H310 (100%): Fatal in contact with skin [Danger Acute toxicity, dermal]

H330 (100%): Fatal if inhaled [Danger Acute toxicity, inhalation]

H373 (98.4%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

H411 (100%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

Aggregated GHS information provided per 63 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

H302: Harmful if swallowed [Warning Acute toxicity, oral]

H320: Causes eye irritation [Warning Serious eye damage/eye irritation]

H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

P203, P260, P264, P264+P265, P270, P280, P301+P317, P305+P351+P338, P318, P319, P330, P337+P317, P405, and P501 (click each P-code to see the statement)

Fresh air, rest. Refer for medical attention.

Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Give one or two glasses of water to drink. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention .

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

Fire Extinguishing Agents Not to Be Used: Water or foam may cause frothing

Fire Extinguishing Agents: For small fires, use water, dry chemical, foam or carbon dioxide (USCG, 1999)

Use water spray, powder, foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.

WATER, CARBON DIOXIDE, DRY CHEMICAL

Use water spray, dry chemical, foam, or carbon dioxide. Water or foam may cause frothing. Approach fire from upwind to avoid hazardous vapors and toxic decomposition products. /Nitropropanes/

Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

SRP: Local exhaust ventilation should be applied wherever there is an incidence of point source emissions or dispersion of regulated contaminants in the work area. Ventilation control of the contaminant as close to its point of generation is both the most economical and safest method to minimize personnel exposure to airborne contaminants.

SMALL SPILLS AND LEAKAGE: If a spill of this chemical occurs, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with acetone and transfer the dampened material to a suitable container. Use absorbent paper dampened with acetone to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with acetone followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

STORAGE PRECAUTIONS: You should store this chemical under refrigerated temperatures, and keep it away from oxidizing materials. STORE AWAY FROM SOURCES OF IGNITION. (NTP, 1992)

Separated from strong oxidants and food and feedstuffs. Well closed.

Store in a cool, dry, well ventilated location. Separate from acids and oxidizing materials. Detached storage must be used.

MATERIALS WHICH ARE TOXIC AS STORED OR WHICH CAN DECOMPOSE INTO TOXIC COMPONENTS ... SHOULD BE STORED IN A COOL WELL VENTILATED PLACE, OUT OF THE DIRECT RAYS OF THE SUN, AWAY FROM AREAS OF HIGH FIRE HAZARD, & SHOULD BE PERIODICALLY INSPECTED. INCOMPATIBLE MATERIALS SHOULD BE ISOLATED ... .

The compound is currently at the Holding Status AEGLs which have been reviewed by the NAC/AEGL Committee and are on hold due to insufficient data to develop AEGL values.

AEGLs Status: Holding

0.86 [mg/m3]

9.4 [mg/m3]

56 [mg/m3]

No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.

The substance is irritating to the eyes, skin and respiratory tract.

The substance may have effects on the blood. This may result in the formation of methaemoglobin.

Self-contained breathing apparatus; butyl rubber gloves; eye goggles; plastic lab coat; protective shoes. (USCG, 1999)

WEAR SPECIAL PROTECTIVE CLOTHING AND POSITIVE PRESSURE SELF-CONTAINED BREATHING APPARATUS.

NO open flames.

PREVENT DISPERSION OF DUST!

Use local exhaust or breathing protection.

Protective gloves. Protective clothing.

Wear safety goggles.

Do not eat, drink, or smoke during work. Wash hands before eating.

2,4-dinitroaniline appears as yellow powder or crystals with a musty odor. Sinks in water. (USCG, 1999)

Yellow or greenish-yellow solid; [Merck Index] Yellow powder; [Alfa Aesar MSDS]

YELLOW NEEDLE-LIKE CRYSTALS OR GREENISH-YELLOW PLATES OR BRIGHT YELLOW SOLID WITH CHARACTERISTIC ODOUR.

YELLOW NEEDLES FROM DIL ACETONE, GREENISH-YELLOW PLATES FROM ALCOHOL.

Musty odor

349 to 352 °F (NTP, 1992)

187.5-188 °C

187-188 °C

435 °F (NTP, 1992)

435 °F (CLOSED CUP)

222-224 °C c.c.

less than 0.1 mg/mL at 73 °F (NTP, 1992)

SOL IN HOT HYDROCHLORIC ACID

PRACTICALLY INSOL IN COLD WATER; VERY SPARINGLY SOL IN BOILING WATER; 5.8 PARTS SOL IN 100 PARTS 88% ALCOHOL @ 18 °C; 1 PART SOL IN 132.6 PARTS OF 95% ALCOHOL @ 21 °C

Solubility in water: none

1.615 at 59 °F (USCG, 1999) - Denser than water; will sink

1.615 g/ml @ 14 °C

1.62 g/cm³

1.615 @25 °C

6.31 (NTP, 1992) - Heavier than air; will sink (Relative to Air)

6.31 (AIR= 1)

0.0000268 [mmHg]

0.000000594 [mm Hg] @25 °C

1.84 (estimated)

WHEN HEATED TO DECOMP, IT EMITS HIGHLY TOXIC FUMES.

Positive

Agilent XCT

Electrospray ionization

formic acid (5.3nM)

MeCN (80%)

DOI:10.1007/s13361-016-1563-1

pKa: 18.46

UV: 3120 (Sadtler Research Laboratories Spectral Collection) /2,3-Dinitroaniline/

UV: 5551 (Sadtler Research Laboratories Spectral Collection) /2,6-Dinitroaniline/

Chemical shift

Crystal structure

Formula unit

Lineshape

Magnetic anisotropy

Space group

Insoluble in water.

Nitro, Nitroso, Nitrate, and Nitrite Compounds, Organic

Amines, Aromatic

Explosive

2,4-DINITROANILINE may decompose violently at elevated temperatures. This compound can react with oxidizing materials, i.e. chlorine/hydrochloric acid. (NTP, 1992). In mixture with powdered charcoal ignited upon heating, [Cahiers, 1980, (99), 278].

DISASTER HAZARD: ... IT CAN REACT WITH OXIDIZING MATERIALS.

The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

Cough. Sore throat.

MAY BE ABSORBED! Redness. Pain.

Redness. Pain.

Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

Methemoglobinemia - The presence of increased methemoglobin in the blood; the compound is classified as secondary toxic effect

LC50 (rat) > 170 mg/m3/4h

2,4-DINITROANILINE ADMIN ORALLY TO RATS SHOWED LOW TOXICITY. AFFECTED NERVOUS SYSTEM, CAUSED WEAK MET- & SULF-HEMOGLOBINEMIA, & DECR LEVEL OF THIOL GROUPS IN BLOOD.

THE DNA DAMAGE INDUCED BY IN VIVO ADMINISTRATION OF 2,4-DINITROANILINE WAS DETERMINED ... . THE TARGET ORGANS FOR ULTIMATE CARCINOGENS PRODUCED IN MICE APPEAR TO BE THE LIVER AND THE KIDNEY. THE VALUES OBTAINED AFTER TREATMENT WITH 2,4-DINITROANILINE FALL IN THE RANGE OF CONTROL MICE.

INHALATION OF 17 MG 2,4-DINITROANILINE/CU M FOR 4 HR/DAY WITHIN THE 1ST 19 OR 7 DAYS OF PREGNANCY INCREASED THE MORTALITY OF RAT EMBRYOS FROM 9.9 TO 18.8 AND 25.3%, RESPECTIVELY, AND DECREASED THE EMBRYO LENGTH ON THE 20TH DAY OF PREGNANCY FROM 29.0 TO 24.9 AND 25.2 MM, RESPECTIVELY. THE 7-DAY EXPOSURE ALSO DECREASED THE ALPHA2-GLOBULIN PERCENTAGE FROM 18.6 TO 14.2%. ...

TWO FRAME-SHIFT HISTIDINE MUTANTS (TA1537 AND TA98) AND 2 BASE-PAIR SUBSTITUTED HISTIDINE MUTANTS (TA1535 AND TA100) OF SALMONELLA TYPHIMURIUM WERE EMPLOYED. BOTH THE SPOT TEST AND PLATE-INCORPORATION ASSAY INDICATED THAT /2,4-DINITROANILINE/ WAS MUTAGENIC WITH THREE OF THE TEST STRAINS. ...

For more Non-Human Toxicity Excerpts (Complete) data for 2,4-DINITROANILINE (6 total), please visit the HSDB record page.

LC50 Pimephales promelas (fathead minnow) 14.2 mg/l/96 hr (Confidence limit 13.5 to 15.0 mg/l). Affected fish lost schooling behavior and swam near the tank surface with half being hyperactive and half hypoactive. They had increased respiration and hemorrhaging, were darkly colored, and lost equilibrium prior to death.

The substance is harmful to aquatic organisms.

2,4-Dinitroaniline may be released to the environment during its production and use in the manufacture of azo dyes. If released to the atmosphere, 2,4-dinitroaniline is expected to degrade relatively rapidly (estimated half-life of 17.7 hr) by reaction with photochemically produced hydroxyl radicals. If released to soil, 2,4-dinitroaniline may undergo a covalent chemical bonding with humic materials which can result in its chemical alteration to a latent form and prevent leaching. In the absence of covalent bonding, moderate leaching may be possible. If released to water, covalent bonding with humic materials in the water column and sediments may result in partitioning from the water column to sediments. By analogy to aromatic amine chemical class, 2,4-dinitroaniline in the water column may be susceptible to photooxidation via hydroxyl and peroxy radicals. One screening study suggests that biodegradation in water will not be significant; however, insufficient data are available to assess the relative importance of biodegradation of 2,4-dinitroaniline in soil or water. 2,4-Dinitroaniline is used in the manufacture of synthetic dyes; therefore, workers involved in the use of 2,4-dinitroaniline as a chemical intermediate may be exposed through inhalation of dust and dermal contact. (SRC)

2,4-Dinitroaniline may be released to the environment during its production and use in the preparation of azo dyes(1,SRC).

TERRESTRIAL FATE: When released to soil, 2,4-dinitroaniline may undergo covalent chemical bonding with humic materials which can result in its chemical alteration to a latent form and tight adsorption. When covalently bound in this latent form, leaching in soil systems is not generally expected to occur. This covalent bonding proceeds in two steps; a rapid and reversible bonding followed by a slower and much less reversible reaction(1,SRC). Leaching in soil may be possible prior to the occurrence of the slower bonding reaction. In the absence of covalent bonding, moderate leaching may be possible (estimated Koc value of 240)(3,4,SRC). Although one biological screening study showed no biodegradation in river and sea water(2), insufficient data are available to assess the relative importance of biodegradation of 2,4-dinitroaniline in soil(SRC).

AQUATIC FATE: By analogy to the aromatic amine chemical class(2), 2,4-dinitroaniline in the water column may be susceptible to photooxidation via hydroxyl and peroxy radicals(SRC). Aromatic amines have also been shown to undergo covalent bonding with humic materials in the water column and in sediment(1); partitioning from the water column to sediment and suspended material may therefore be important(SRC). Although one biological degradation study found evidence of no microbial degradation(3), insufficient data are available to assess the relative importance of biodegradation of 2,4-dinitroaniline in water. An estimated BCF value of 15(4,SRC) suggests that it will not bioconcentrate significantly in aquatic organisms(SRC). Aquatic hydrolysis and volatilization do not appear to be environmentally important(SRC).

ATMOSPHERIC FATE: Based upon an estimated vapor pressure of 5.94X10-7 mm Hg at 25 °C(1), 2,4-dinitroaniline may exist in both the vapor and the particulate-phase in the ambient atmosphere(2,SRC). It is degraded relatively rapidly in the vapor phase in an average ambient atmosphere by reaction with photochemically produced hydroxyl radicals at an estimated half-life of about 17.7 hr(3,SRC).

2,4-Dinitroaniline at an initial concn of 100 ppm showed no biodegradation in river and sea water after 3 days using a cultivation test method(1).

The rate constant for the vapor-phase reaction of 2,4-dinitroaniline with photochemically produced hydroxyl radicals has been estimated to be 2.18E-11 cu cm/molecule-sec at 25 °C which corresponds to an atmospheric half-life of about 17.7 hr at an atmospheric concn of 5X10+5 hydroxyl radicals per cu cm(1,SRC). Aromatic amines are generally resistant to aqueous environmental hydrolysis(2); therefore, 2,4-dinitroaniline is not expected to hydrolyze in water(SRC). Photolysis is expected to be significant; 2,4-dinitroaniline does absorb UV light >290 nm(SRC). However, no rate data were located. As a class, aromatic amines react relatively rapidly in sunlit natural water via reaction with photochemically produced hydroxyl radicals and peroxy radicals(3); typical half-lives for hydroxyl radical and peroxy radical reaction are on the order of 19-30 sunlight hours(3); however, rate data specific to 2,4-dinitroaniline were not located(SRC).

Based on an estimated log Kow of 1.84(2), the bioconcentration factor (BCF) for 2,4-dinitroaniline can be estimated to be about 15 from a recommended regression-derived equation(1,SRC). This BCF value suggests that bioconcentration in aquatic organisms may not be significant(SRC).

Aromatic amines have been observed to undergo rapid and reversible covalent bonding with humic materials in aqueous solution; the initial bonding reaction is followed by a slower and much less reversible reaction believed to represent the addition of the amine to quinoidal structures followed by oxidation of the product to give an amino-substituted quinone; these processes represent pathways by which aromatic amines may be converted to latent forms in the biosphere(3). In the absence of covalent bonding, a Koc of approximately 240 can be estimated for 2,4-dinitroaniline based on an estimated log Kow of 1.84(2) and a recommended regression-derived equation(1,SRC); this Koc value suggests medium soil mobility(4).

The Henry's Law constant for 2,4-dinitroaniline can be estimated to be approximately 1.51X10-10 atm-cu m/mole at 25 °C using a chemical structure estimation method(2,SRC). This value of Henry's Law constant suggests that 2,4-dinitroaniline is essentially nonvolatile from water(1).

2,4-Dinitroaniline is used in the manufacture of azo dyes(1); therefore, workers involved in the preparation of these dyes may be exposed through dermal contact or inhalation of dust(SRC).

LC50 Pimephales promelas (fathead minnow) 14.2 mg/l/96 hr (Confidence limit 13.5 to 15.0 mg/l). Affected fish lost schooling behavior and swam near the tank surface with half being hyperactive and half hypoactive. They had increased respiration and hemorrhaging, were darkly colored, and lost equilibrium prior to death.

The substance is harmful to aquatic organisms.

2,4-Dinitroaniline may be released to the environment during its production and use in the manufacture of azo dyes. If released to the atmosphere, 2,4-dinitroaniline is expected to degrade relatively rapidly (estimated half-life of 17.7 hr) by reaction with photochemically produced hydroxyl radicals. If released to soil, 2,4-dinitroaniline may undergo a covalent chemical bonding with humic materials which can result in its chemical alteration to a latent form and prevent leaching. In the absence of covalent bonding, moderate leaching may be possible. If released to water, covalent bonding with humic materials in the water column and sediments may result in partitioning from the water column to sediments. By analogy to aromatic amine chemical class, 2,4-dinitroaniline in the water column may be susceptible to photooxidation via hydroxyl and peroxy radicals. One screening study suggests that biodegradation in water will not be significant; however, insufficient data are available to assess the relative importance of biodegradation of 2,4-dinitroaniline in soil or water. 2,4-Dinitroaniline is used in the manufacture of synthetic dyes; therefore, workers involved in the use of 2,4-dinitroaniline as a chemical intermediate may be exposed through inhalation of dust and dermal contact. (SRC)

2,4-Dinitroaniline may be released to the environment during its production and use in the preparation of azo dyes(1,SRC).

TERRESTRIAL FATE: When released to soil, 2,4-dinitroaniline may undergo covalent chemical bonding with humic materials which can result in its chemical alteration to a latent form and tight adsorption. When covalently bound in this latent form, leaching in soil systems is not generally expected to occur. This covalent bonding proceeds in two steps; a rapid and reversible bonding followed by a slower and much less reversible reaction(1,SRC). Leaching in soil may be possible prior to the occurrence of the slower bonding reaction. In the absence of covalent bonding, moderate leaching may be possible (estimated Koc value of 240)(3,4,SRC). Although one biological screening study showed no biodegradation in river and sea water(2), insufficient data are available to assess the relative importance of biodegradation of 2,4-dinitroaniline in soil(SRC).

AQUATIC FATE: By analogy to the aromatic amine chemical class(2), 2,4-dinitroaniline in the water column may be susceptible to photooxidation via hydroxyl and peroxy radicals(SRC). Aromatic amines have also been shown to undergo covalent bonding with humic materials in the water column and in sediment(1); partitioning from the water column to sediment and suspended material may therefore be important(SRC). Although one biological degradation study found evidence of no microbial degradation(3), insufficient data are available to assess the relative importance of biodegradation of 2,4-dinitroaniline in water. An estimated BCF value of 15(4,SRC) suggests that it will not bioconcentrate significantly in aquatic organisms(SRC). Aquatic hydrolysis and volatilization do not appear to be environmentally important(SRC).

ATMOSPHERIC FATE: Based upon an estimated vapor pressure of 5.94X10-7 mm Hg at 25 °C(1), 2,4-dinitroaniline may exist in both the vapor and the particulate-phase in the ambient atmosphere(2,SRC). It is degraded relatively rapidly in the vapor phase in an average ambient atmosphere by reaction with photochemically produced hydroxyl radicals at an estimated half-life of about 17.7 hr(3,SRC).

2,4-Dinitroaniline at an initial concn of 100 ppm showed no biodegradation in river and sea water after 3 days using a cultivation test method(1).

The rate constant for the vapor-phase reaction of 2,4-dinitroaniline with photochemically produced hydroxyl radicals has been estimated to be 2.18E-11 cu cm/molecule-sec at 25 °C which corresponds to an atmospheric half-life of about 17.7 hr at an atmospheric concn of 5X10+5 hydroxyl radicals per cu cm(1,SRC). Aromatic amines are generally resistant to aqueous environmental hydrolysis(2); therefore, 2,4-dinitroaniline is not expected to hydrolyze in water(SRC). Photolysis is expected to be significant; 2,4-dinitroaniline does absorb UV light >290 nm(SRC). However, no rate data were located. As a class, aromatic amines react relatively rapidly in sunlit natural water via reaction with photochemically produced hydroxyl radicals and peroxy radicals(3); typical half-lives for hydroxyl radical and peroxy radical reaction are on the order of 19-30 sunlight hours(3); however, rate data specific to 2,4-dinitroaniline were not located(SRC).

Based on an estimated log Kow of 1.84(2), the bioconcentration factor (BCF) for 2,4-dinitroaniline can be estimated to be about 15 from a recommended regression-derived equation(1,SRC). This BCF value suggests that bioconcentration in aquatic organisms may not be significant(SRC).

Aromatic amines have been observed to undergo rapid and reversible covalent bonding with humic materials in aqueous solution; the initial bonding reaction is followed by a slower and much less reversible reaction believed to represent the addition of the amine to quinoidal structures followed by oxidation of the product to give an amino-substituted quinone; these processes represent pathways by which aromatic amines may be converted to latent forms in the biosphere(3). In the absence of covalent bonding, a Koc of approximately 240 can be estimated for 2,4-dinitroaniline based on an estimated log Kow of 1.84(2) and a recommended regression-derived equation(1,SRC); this Koc value suggests medium soil mobility(4).

The Henry's Law constant for 2,4-dinitroaniline can be estimated to be approximately 1.51X10-10 atm-cu m/mole at 25 °C using a chemical structure estimation method(2,SRC). This value of Henry's Law constant suggests that 2,4-dinitroaniline is essentially nonvolatile from water(1).

2,4-Dinitroaniline is used in the manufacture of azo dyes(1); therefore, workers involved in the preparation of these dyes may be exposed through dermal contact or inhalation of dust(SRC).

/GUIDE 153: SUBSTANCES - TOXIC AND/OR CORROSIVE (COMBUSTIBLE)/ Health: TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. /Dinitroanilines/

/GUIDE 153: SUBSTANCES - TOXIC AND/OR CORROSIVE (COMBUSTIBLE)/ Fire or Explosion: Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Those substances designated with a "P" may polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form. /Dinitroanilines/

/GUIDE 153: SUBSTANCES - TOXIC AND/OR CORROSIVE (COMBUSTIBLE)/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate enclosed areas. /Dinitroanilines/

/GUIDE 153: SUBSTANCES - TOXIC AND/OR CORROSIVE (COMBUSTIBLE)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible. /Dinitroanilines/

For more DOT Emergency Guidelines (Complete) data for 2,4-DINITROANILINE (8 total), please visit the HSDB record page.

UN 1596; Dinitroanilines

IMO 6.1; Dinitroanilines

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Do not transport with food and feedstuffs.

Symbol: T+, N; R: 26/27/28-33-51/53; S: (1/2)-28-36/37-45-61

UN Hazard Class: 6.1; UN Pack Group: II