Benzenesulfonyl chloride

H302 (98.7%): Harmful if swallowed [Warning Acute toxicity, oral]

H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

H317 (27.7%): May cause an allergic skin reaction [Warning Sensitization, Skin]

H318 (27%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

H319 (14.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H332 (27%): Harmful if inhaled [Warning Acute toxicity, inhalation]

H334 (27.7%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]

P233, P260, P261, P264, P264+P265, P270, P271, P272, P280, P284, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P321, P330, P333+P317, P337+P317, P342+P316, P362+P364, P363, P403, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 159 reports by companies from 17 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

H302: Harmful if swallowed [Warning Acute toxicity, oral]

H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]

H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure]

P260, P264, P264+P265, P270, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P308+P316, P316, P317, P321, P330, P363, P405, and P501 (click each P-code to see the statement)

INHALATION: Move victim to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

EYES OR SKIN: Flush with running water for at least 15 min.; hold eyelids open if necessary. Wash skin with soap and water. Remove and isolate contaminated clothing and shoes at the site. Maintain normal body temperature and keep victim quiet. Keep victim under observation for delayed effects.

INGESTION: If unconscious or having convulsions, do nothing except keep victim warm. (USCG, 1999)

General First Aid:

· Call 911 or emergency medical service.

· Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.

· Move victim to fresh air if it can be done safely.

· Administer oxygen if breathing is difficult.

· If victim is not breathing:

-- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.

-- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).

-- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.

· Remove and isolate contaminated clothing and shoes.

· For minor skin contact, avoid spreading material on unaffected skin.

· In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.

· For severe burns, immediate medical attention is required.

· Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed.

· Keep victim calm and warm.

· Keep victim under observation.

· For further assistance, contact your local Poison Control Center.

· Note: Basic Life Support (BLS) and Advanced Life Support (ALS) should be done by trained professionals.

Specific First Aid:

· For corrosives, in case of contact, immediately flush skin or eyes with running water for at least 30 minutes. Additional flushing may be required.

· Removal of solidified molten material from skin requires medical assistance.

In Canada, an Emergency Response Assistance Plan (ERAP) may be required for this product. Please consult the shipping paper and/or the "ERAP" section.

Excerpt from ERG Guide 156 [Substances - Toxic and/or Corrosive (Combustible / Water-Sensitive)]:

Note: Most foams will react with the material and release corrosive/toxic gases. CAUTION: For Acetyl bromide (UN1716), use CO2 or dry chemical only.

SMALL FIRE: CO2, dry chemical, dry sand, alcohol-resistant foam.

LARGE FIRE: Water spray, fog or alcohol-resistant foam. FOR CHLOROSILANES, DO NOT USE WATER; use alcohol-resistant foam. If it can be done safely, move undamaged containers away from the area around the fire. Avoid aiming straight or solid streams directly onto the product.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. (ERG, 2024)

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Keep unauthorized personnel away.

· Stay upwind, uphill and/or upstream.

· Ventilate closed spaces before entering, but only if properly trained and equipped.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

· All equipment used when handling the product must be grounded.

· Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.

· Stop leak if you can do it without risk.

· A vapor-suppressing foam may be used to reduce vapors.

· FOR CHLOROSILANES, use alcohol-resistant foam to reduce vapors.

· DO NOT GET WATER on spilled substance or inside containers.

· Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material.

· Prevent entry into waterways, sewers, basements or confined areas.

Small Spill

· Cover with DRY earth, DRY sand or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain.

· Use clean, non-sparking tools to collect material and place it into loosely covered plastic containers for later disposal.

Excerpt from ERG Guide 156 [Substances - Toxic and/or Corrosive (Combustible / Water-Sensitive)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Immediate precautionary measure

· Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

· For highlighted materials: see Table 1 - Initial Isolation and Protective Action Distances.

· For non-highlighted materials: increase the immediate precautionary measure distance, in the downwind direction, as necessary.

· If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number U020, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.

A potential candidate for liquid injection incineration at a temperature range of 650 to 1,600 °C and a residence time of 0.1 to 2 seconds. A potential candidate for rotary kiln incineration at a temperature range of 820 to 1,600 °C and residence times of seconds for liquids and gases, and hours for solids.

Excerpt from ERG Guide 156 [Substances - Toxic and/or Corrosive (Combustible / Water-Sensitive)]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. A vapor-suppressing foam may be used to reduce vapors. FOR CHLOROSILANES, use alcohol-resistant foam to reduce vapors. DO NOT GET WATER on spilled substance or inside containers. Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material. Prevent entry into waterways, sewers, basements or confined areas.

SMALL SPILL: Cover with DRY earth, DRY sand or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain. Use clean, non-sparking tools to collect material and place it into loosely covered plastic containers for later disposal. (ERG, 2024)

· Wear positive pressure self-contained breathing apparatus (SCBA).

· Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE.

· Structural firefighters' protective clothing provides thermal protection but only limited chemical protection.

0.77 [mg/m3]

8.4 [mg/m3]

51 [mg/m3]

· Note: Most foams will react with the material and release corrosive/toxic gases.

CAUTION: For Acetyl bromide (UN1716), use CO2 or dry chemical only.

Small Fire

· CO2, dry chemical, dry sand, alcohol-resistant foam.

Large Fire

· Water spray, fog or alcohol-resistant foam.

· FOR CHLOROSILANES, DO NOT USE WATER; use alcohol-resistant foam.

· If it can be done safely, move undamaged containers away from the area around the fire.

· Avoid aiming straight or solid streams directly onto the product.

Fire Involving Tanks, Rail Tank Cars or Highway Tanks

· Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.

· Do not get water inside containers.

· Cool containers with flooding quantities of water until well after fire is out.

· Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.

· ALWAYS stay away from tanks in direct contact with flames.

/IN USSR/ MAX ALLOWABLE CONCN OF 0.3 MG/CU M AIR.

Wear positive pressure breathing apparatus and special protective clothing. (USCG, 1999)

Benzenesulfonyl chloride appears as a colorless to slightly yellow solid that melts at approximately 40 °F. Very irritating to skin, eyes and mucous membranes. May emit toxic fumes when heated to high temperatures. Used to make dyes and other chemicals.

Clear, oily liquid; [HSDB]

COLORLESS, OILY LIQUID

484.7 °F at 760 mmHg (USCG, 1999)

177 °C AT 100 MM HG; 120 °C AT 10 MM HG; DECOMP 251-252 °C AT 760 MM HG

58.1 °F (USCG, 1999)

greater than 233.6 °F (USCG, 1999)

Flash point > 233 °F

INSOL IN WATER; SOL IN ETHER, ALCOHOL

1.3842 at 59 °F (USCG, 1999) - Denser than water; will sink

SP GR: 1.3842 AT 15 °C/15 °C

1.384 @ 15°C

0.06 [mmHg]

0.068 [mm Hg] @25 °C

STABLE TOWARD COLD WATER

DECOMP 251-252 °C AT 760 MM HG

SOLIDIFIES AT 0 °C

Schoenflies notation

Boiling point

Chemical bond

Chemical shift

Dielectric constant

Heat of sublimation

Internuclear distance

Lineshape

Molecular structure

Nuclear quadrupole resonance spectroscopy

Optical coefficient

Phase transition

Point group

Quadrupole coupling

Refractive index

Rotational excitation cross section

Surface tension

Vapor pressure

Vibrational mode frequency

Toxic Gases & Vapors -> Acid Halides

Corrosives

Reactive agents - 1st degree

Insoluble and stable in cold water [Merck]. Decomposes in hot water to produce corrosive and toxic hydrochloric acid and benzenesulfonic acid. Rate of reaction decreases as temperature decreases.

Acyl Halides, Sulfonyl Halides, and Chloroformates

Water-Reactive

BENZENESULFONYL CHLORIDE is incompatible with strong oxidizing agents and bases, including amines. Corrodes metals in the presence of water due to slow formation of hydrochloric acid and benzenesulfonic acid (USCG, 1999). May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

IN ABSENCE OF DILUENT OR OTHER EFFECTIVE CONTROL OF REACTION RATE, /DIMETHYL/ SULFOXIDE REACTS VIOLENTLY OR EXPLOSIVELY WITH ... BENZENESULFONYL CHLORIDE ... .

Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

Dermatotoxin - Skin burns.

Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.

LCLo (rat) = 1,870 mg/m3/1h

LD50 Mouse acute oral 0.4 to 3.2 g/kg /Benzenesulfonic acid/

PERCUTANEOUS ABSORPTION WHICH CAN OCCUR ON MUCOUS MEMBRANES HAS BIOLOGICAL EFFECT ON SKIN & RESULTS IN REVERSIBLE TOXIC DAMAGE TO LIVER; 3 SUCH CASES ARE DESCRIBED. 2 PATIENTS EXPERIENCED VERY SEVERE SHOCK WHICH WAS BROUGHT UNDER CONTROL AFTER 1 TO 1.5 HR. POSSIBILITY THAT IMMEDIATE TYPE ALLERGIC REACTION OCCURS IS DISCUSSED.

DAMAGE TO LIVER, LUNG, THYROID & CNS IS CHARACTERISTIC OF REPEATED ORAL OR INHALATION ADMIN TO RATS.

LC50 Brown trout yearlings 3 mg/l/48 hr /Static bioassay/

Benzenesulfonyl chloride may be released to the environment as a result of its manufacture and use as a catalyst and as an intermediate in the production of phenol and other organic chemicals. If benzenesulfonyl chloride is released to soil, it will be expected to rapidly hydrolyze if the soil is moist, based upon the rapid hydrolysis observed in aqueous solution. Since it rapidly hydrolyzes, adsorption to and volatilization from moist soil are not expected to be significant processes. Based upon an estimated vapor pressure of 0.068 mm Hg at 25 °C, volatilization from dry near-surface soil or other surfaces may be significant processes. If released to water, it will be expected to rapidly hydrolyze with a half-life of 5.1 min at 21 °C. Since it rapidly hydrolyzes, bioconcentration, volatilization, and adsorption to sediment and suspended solids are not expected to be significant processes. No data were located concerning biodegradation, but benzenesulfonyl chloride probably chemically hydrolyzes significantly faster than it biodegrades. Direct photolysis is not expected to be an important removal process in surface waters. If released to the atmosphere, it will be expected to exist almost entirely in the vapor phase based upon its estimated vapor pressure. It will be susceptible to photooxidation via vapor phase reaction with photochemically hydroxyl radicals. An atmospheric half-life of 7.9 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm has been estimated for this process based upon an estimated rate constant. Hydrolysis of benzenesulfonyl chloride in moist air may be an important removal process based upon its rapid hydrolysis in aqueous solution. Direct photolysis is not expected to be an important removal process in the atmosphere. Exposure to benzenesulfonyl chloride will be primarily occupational via inhalation and possibly dermal contact. (SRC)

Benzenesulfony chloride may be released to the environmet as a result of its manufacture and use as a catalyst and as an intermediate in the production of phenol and other organic chemicals(1). Benzenesulfonyl chloride has been used in the Friedel-Crafts sulfonylation of benzene(2).

TERRESTRIAL FATE: If benzenesulfonyl chloride is released to soil, it will be expected to rapidly hydrolyze if the soil is moist, based upon a half-life of 5.1 min at 21 °C(SRC). Since it rapidly hydrolyzes, adsorption to and volatilization from moist soil are not expected to be significant processes, although no data specifically regarding the fate of benzenesulfonyl chloride in soil were located(SRC). Based upon an estimated vapor pressure of 0.068 mm Hg at 25 deg(2,SRC), volatilization from dry near-surface soil or other surfaces may be significant processes(SRC).

AQUATIC FATE: If benzenesulfonyl chloride is released to water, it will be expected to rapidly hydrolyze with a half-life of 5.1 min at 21 °C(1,SRC). Since it rapidly hydrolyzes, bioconcentration, volatilization, and adsorption to sediment and suspended solids are not expected to be significant processes(SRC). No data were located concerning biodegradation, but benzenesulfonyl chloride probably chemically hydrolyzes significantly faster than it biodegradates(SRC). Direct photolysis is not expected to be an important removal process in surface waters(2,SRC).

ATMOSPHERIC FATE: If benzenesulfonyl chloride is released to the atmosphere, it will be expected to exist almost entirely in the vapor phase(1) based upon an estimated vapor pressure of 0.068 mm Hg at 25 °C(2,SRC). It will be susceptible to photooxidation via vapor phase reaction with photochemically produced hydroxyl radicals. An atmospheric half-life of 7.9 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm has been calculated for this process based upon an estimated rate constant(3,SRC). Hydrolysis of benzenesulfonyl chloride in moist air may be significant based upon its rapid hydrolysis in aqueous solution(4,SRC). Direct photolysis is not expected to be an important removal process in the atmosphere(5,SRC).

No data were located concerning the biodegradation of benzenesulfonyl chloride either in natural systems or in laboratory studies(SRC). Since benzenesulfonyl chloride rapidly hydrolyzes in water(1,SRC), biodegradation probably will not be an important process in the environment(SRC).

The measured overall rate constant for hydrolysis of benzenesulfonyl chloride in a 1% aqueous dioxane solution at 21 °C is 2.25X10-3 sec-1(1) which corresponds to a half-life of 5.1 min(1,SRC). The calculated half-life for hydrolysis at 10 °C is 12.9 min(1,SRC). The products of hydrolysis are benzenesulfonic acid and hydrogen chloride(SRC). The rate constant for the vapor phase reaction of benzenesulfonyl chloride with photochemically produced hydroxyl radicals has been estimated to be 2.04X10-12 cu cm/molecule-sec at 25 °C which corresponds to an atmospheric half-life of 7.9 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm (2,SRC). Direct photolysis is not expected to be a significant removal process since the compound absorbs very little light at wavelengths above 290 nm(3).

Since benzenesulfonyl chloride rapidly hydrolyzes in water(1), bioconcentration in aquatic organisms is not expected to be a significant process(SRC).

Since benzenesulfonyl chloride rapidly hydrolyzes in water(1) and presumably in moist soil(SRC), adsorption to soil is not expected to be a significant process(SRC).

Due to a lack of data, it is not possible to estimate the half-life for volatilization from water or soil. Since benzenesulfonyl chloride rapidly hydrolyzes in water(1), however, volatilization from water and moist soil are not expected to be significant(SRC). Based upon an estimated vapor pressure of 0.068 mm Hg at 25 °C(2,SRC), volatilization of benzenesulfonyl chloride from surfaces and near-surface dry soil may be significant processes(SRC).

Exposure to benzenesulfonyl chloride will be primarily occupational via inhalation and possibly dermal contact. (SRC)

NIOSH (NOES Survey 1981-1983) has statistically estimated that 851 workers are potentially exposed to benzenesulfonyl chloride in the USA(1). NIOSH (NOHS Survey 1972-1974) has statistically estimated that 194 workers are potentially exposed to benzenesulfonyl chloride in the USA(2).

LC50 Brown trout yearlings 3 mg/l/48 hr /Static bioassay/

Benzenesulfonyl chloride may be released to the environment as a result of its manufacture and use as a catalyst and as an intermediate in the production of phenol and other organic chemicals. If benzenesulfonyl chloride is released to soil, it will be expected to rapidly hydrolyze if the soil is moist, based upon the rapid hydrolysis observed in aqueous solution. Since it rapidly hydrolyzes, adsorption to and volatilization from moist soil are not expected to be significant processes. Based upon an estimated vapor pressure of 0.068 mm Hg at 25 °C, volatilization from dry near-surface soil or other surfaces may be significant processes. If released to water, it will be expected to rapidly hydrolyze with a half-life of 5.1 min at 21 °C. Since it rapidly hydrolyzes, bioconcentration, volatilization, and adsorption to sediment and suspended solids are not expected to be significant processes. No data were located concerning biodegradation, but benzenesulfonyl chloride probably chemically hydrolyzes significantly faster than it biodegrades. Direct photolysis is not expected to be an important removal process in surface waters. If released to the atmosphere, it will be expected to exist almost entirely in the vapor phase based upon its estimated vapor pressure. It will be susceptible to photooxidation via vapor phase reaction with photochemically hydroxyl radicals. An atmospheric half-life of 7.9 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm has been estimated for this process based upon an estimated rate constant. Hydrolysis of benzenesulfonyl chloride in moist air may be an important removal process based upon its rapid hydrolysis in aqueous solution. Direct photolysis is not expected to be an important removal process in the atmosphere. Exposure to benzenesulfonyl chloride will be primarily occupational via inhalation and possibly dermal contact. (SRC)

Benzenesulfony chloride may be released to the environmet as a result of its manufacture and use as a catalyst and as an intermediate in the production of phenol and other organic chemicals(1). Benzenesulfonyl chloride has been used in the Friedel-Crafts sulfonylation of benzene(2).

TERRESTRIAL FATE: If benzenesulfonyl chloride is released to soil, it will be expected to rapidly hydrolyze if the soil is moist, based upon a half-life of 5.1 min at 21 °C(SRC). Since it rapidly hydrolyzes, adsorption to and volatilization from moist soil are not expected to be significant processes, although no data specifically regarding the fate of benzenesulfonyl chloride in soil were located(SRC). Based upon an estimated vapor pressure of 0.068 mm Hg at 25 deg(2,SRC), volatilization from dry near-surface soil or other surfaces may be significant processes(SRC).

AQUATIC FATE: If benzenesulfonyl chloride is released to water, it will be expected to rapidly hydrolyze with a half-life of 5.1 min at 21 °C(1,SRC). Since it rapidly hydrolyzes, bioconcentration, volatilization, and adsorption to sediment and suspended solids are not expected to be significant processes(SRC). No data were located concerning biodegradation, but benzenesulfonyl chloride probably chemically hydrolyzes significantly faster than it biodegradates(SRC). Direct photolysis is not expected to be an important removal process in surface waters(2,SRC).

ATMOSPHERIC FATE: If benzenesulfonyl chloride is released to the atmosphere, it will be expected to exist almost entirely in the vapor phase(1) based upon an estimated vapor pressure of 0.068 mm Hg at 25 °C(2,SRC). It will be susceptible to photooxidation via vapor phase reaction with photochemically produced hydroxyl radicals. An atmospheric half-life of 7.9 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm has been calculated for this process based upon an estimated rate constant(3,SRC). Hydrolysis of benzenesulfonyl chloride in moist air may be significant based upon its rapid hydrolysis in aqueous solution(4,SRC). Direct photolysis is not expected to be an important removal process in the atmosphere(5,SRC).

No data were located concerning the biodegradation of benzenesulfonyl chloride either in natural systems or in laboratory studies(SRC). Since benzenesulfonyl chloride rapidly hydrolyzes in water(1,SRC), biodegradation probably will not be an important process in the environment(SRC).

The measured overall rate constant for hydrolysis of benzenesulfonyl chloride in a 1% aqueous dioxane solution at 21 °C is 2.25X10-3 sec-1(1) which corresponds to a half-life of 5.1 min(1,SRC). The calculated half-life for hydrolysis at 10 °C is 12.9 min(1,SRC). The products of hydrolysis are benzenesulfonic acid and hydrogen chloride(SRC). The rate constant for the vapor phase reaction of benzenesulfonyl chloride with photochemically produced hydroxyl radicals has been estimated to be 2.04X10-12 cu cm/molecule-sec at 25 °C which corresponds to an atmospheric half-life of 7.9 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm (2,SRC). Direct photolysis is not expected to be a significant removal process since the compound absorbs very little light at wavelengths above 290 nm(3).

Since benzenesulfonyl chloride rapidly hydrolyzes in water(1), bioconcentration in aquatic organisms is not expected to be a significant process(SRC).

Since benzenesulfonyl chloride rapidly hydrolyzes in water(1) and presumably in moist soil(SRC), adsorption to soil is not expected to be a significant process(SRC).

Due to a lack of data, it is not possible to estimate the half-life for volatilization from water or soil. Since benzenesulfonyl chloride rapidly hydrolyzes in water(1), however, volatilization from water and moist soil are not expected to be significant(SRC). Based upon an estimated vapor pressure of 0.068 mm Hg at 25 °C(2,SRC), volatilization of benzenesulfonyl chloride from surfaces and near-surface dry soil may be significant processes(SRC).

Exposure to benzenesulfonyl chloride will be primarily occupational via inhalation and possibly dermal contact. (SRC)

NIOSH (NOES Survey 1981-1983) has statistically estimated that 851 workers are potentially exposed to benzenesulfonyl chloride in the USA(1). NIOSH (NOHS Survey 1972-1974) has statistically estimated that 194 workers are potentially exposed to benzenesulfonyl chloride in the USA(2).

Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number U020, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.

A potential candidate for liquid injection incineration at a temperature range of 650 to 1,600 °C and a residence time of 0.1 to 2 seconds. A potential candidate for rotary kiln incineration at a temperature range of 820 to 1,600 °C and residence times of seconds for liquids and gases, and hours for solids.

/GUIDE 156: SUBSTANCES - TOXIC and/or CORROSIVE (Combustible/Water-Sensitive)/ Fire or Explosion: Combustible material: may burn but does not ignite readily. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.

/GUIDE 156: SUBSTANCES - TOXIC and/or CORROSIVE (Combustible/Water-Sensitive)/ Health: TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Contact with molten substance may cause severe burns to skin and eyes. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

/GUIDE 156: SUBSTANCES - TOXIC and/or CORROSIVE (Combustible/Water-Sensitive)/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate enclosed areas.

/GUIDE 156: SUBSTANCES - TOXIC and/or CORROSIVE (Combustible/Water-Sensitive)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.

For more DOT Emergency Guidelines (Complete) data for BENZENESULFONYL CHLORIDE (8 total), please visit the HSDB record page.

UN 2225; Benzenesulphonyl chloride

IMO 8.0; Benzenesulphonyl chloride

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./

The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Corrosive